| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beren Millidge, Yuhang Song, Armin Lak, Mark E Walton, Rafal Bogac. Reward Bases: A simple mechanism for adaptive acquisition of multiple reward types. PLoS computational biology. vol 20. issue 11. 2024-11-19. PMID:39561186. |
this model predicts that individual dopamine neurons should encode the errors associated with some reward dimensions more than with others. |
2024-11-19 |
2024-11-23 |
Not clear |
| Beren Millidge, Yuhang Song, Armin Lak, Mark E Walton, Rafal Bogac. Reward Bases: A simple mechanism for adaptive acquisition of multiple reward types. PLoS computational biology. vol 20. issue 11. 2024-11-19. PMID:39561186. |
we observed that in addition to subjective economic value, dopamine neurons encode a gradient of reward dimensions; some neurons respond most to stimuli predicting food rewards while the others respond more to stimuli predicting fluids. |
2024-11-19 |
2024-11-23 |
Not clear |
| Rini Gusya Liza, Yaslinda Yaunin, Yanwirasti, Rauza Sukma Rit. Association Between Opioid Receptor Kappa 1 Gene Polymorphism, Kappa Opioid Receptor Level and Dynorphin Level with Non-Suicidal Self-Injury. Pakistan journal of biological sciences : PJBS. vol 27. issue 11. 2024-11-18. PMID:39551954. |
it is assumed that nssi is involved in the mesocortical dopamine reward system, the endogenous opioid system and the overstimulation of the stress system. |
2024-11-18 |
2024-11-22 |
human |
| Michelle A Carroll Turpin, Steven M Starks, Maureen O Grissom, Brian C Ree. Addiction Medicine: Opioid Use Disorder. FP essentials. vol 546. 2024-11-18. PMID:39556473. |
substance use disorders share neurobiological dysregulation of the central motivation and reward pathway (powered by dopamine) that manifests as a cycle of addiction driven by impulse and compulsion. |
2024-11-18 |
2024-11-22 |
Not clear |
| Farhan Mohammad, Yishan Mai, Joses Ho, Xianyuan Zhang, Stanislav Ott, James Charles Stewart, Adam Claridge-Chan. Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion. PLoS biology. vol 22. issue 11. 2024-11-18. PMID:39556592. |
while both immediate actions and reinforcement learning are instructed by dopamine, how dopaminergic systems maintain coherence between these 2 reward functions is unknown. |
2024-11-18 |
2024-11-22 |
drosophila_melanogaster |
| Mahsa Mohammadi, Seyed Erfan Omidiani, Ronak Azizbeigi, Abbas Haghparas. Cannabidiol Plays a Modulatory Function on the Methamphetamine-Induced Reward Through Hippocampal D2-Like Dopamine Receptors. Neurochemical research. vol 50. issue 1. 2024-11-14. PMID:39540967. |
cannabidiol plays a modulatory function on the methamphetamine-induced reward through hippocampal d2-like dopamine receptors. |
2024-11-14 |
2024-11-17 |
rat |
| Zarah Le Houcq Corbi, Alexander Soutsche. Neural reward system reflects individual value comparison strategy in cost-benefit decisions. Communications biology. vol 7. issue 1. 2024-11-13. PMID:39533059. |
strikingly, manipulating activation in the dopaminergic reward system reveals that dopamine antagonism counteracts the engagement in an individual's dominant value comparison strategy. |
2024-11-13 |
2024-11-17 |
Not clear |
| Sonia Aroni, Claudia Sagheddu, Marco Pistis, Anna Lisa Munton. Functional Adaptation in the Brain Habenulo-Mesencephalic Pathway During Cannabinoid Withdrawal. Cells. vol 13. issue 21. 2024-11-08. PMID:39513916. |
the mesolimbic reward system originating from dopamine neurons in the ventral tegmental area (vta) of the midbrain shows a profound reduction in function during cannabinoid withdrawal. |
2024-11-08 |
2024-11-16 |
Not clear |
| Zhen Tian, Jiachen Song, Xuying Zhao, Yiming Zhou, Xi Chen, Qiumin Le, Feifei Wang, Lan Ma, Xing Li. The interhemispheric amygdala-accumbens circuit encodes negative valence in mice. Science (New York, N.Y.). vol 386. issue 6722. 2024-11-07. PMID:39509508. |
selective activation of contralateral bla-nac projections activated d2-positive medium spiny neurons (d2-msns), reduced nac dopamine levels, and caused aversion, whereas selective activation of ipsilateral bla-nac projections activated d1-msns, increased nac dopamine levels, and induced reward. |
2024-11-07 |
2024-11-16 |
mouse |
| Silvia Giatti, Lucia Cioffi, Silvia Diviccaro, Gabriela Chrostek, Rocco Piazza, Roberto Cosimo Melcang. Transcriptomic Profile of the Male Rat Hypothalamus and Nucleus Accumbens After Paroxetine Treatment and Withdrawal: Possible Causes of Sexual Dysfunction. Molecular neurobiology. 2024-11-04. PMID:39495228. |
moreover, degs related to neurotransmitters with a role in sexual behavior and the reward system, such as dopamine (e.g., sialyltransferase 8b-st8sia3), glutamate (e.g., glutamate receptor ionotropic delta-2-grid2) and gaba (e.g., glutamate decarboxylase type 2-gad2) or associated with neurexin and neuroligin pathways and brain-derived neurotrophic factor (bdnf) signaling, were reported to be dysregulated in the nac, further confirming dysfunction in this brain area. |
2024-11-04 |
2024-11-06 |
rat |
| Merridee J Lefner, Bita Moghadda. Reward and punishment contingency shifting reveals distinct roles for VTA dopamine and GABA neurons in behavioral flexibility. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416212. |
reward and punishment contingency shifting reveals distinct roles for vta dopamine and gaba neurons in behavioral flexibility. |
2024-10-17 |
2024-10-19 |
rat |
| Merridee J Lefner, Bita Moghadda. Reward and punishment contingency shifting reveals distinct roles for VTA dopamine and GABA neurons in behavioral flexibility. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416212. |
dopamine and gaba neurons in the ventral tegmental area (vta) are implicated in reward and punishment learning, yet little is known about how each population adapts when the predicted outcome valence changes. |
2024-10-17 |
2024-10-19 |
rat |
| Merridee J Lefner, Bita Moghadda. Reward and punishment contingency shifting reveals distinct roles for VTA dopamine and GABA neurons in behavioral flexibility. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416212. |
we measured vta dopamine and gaba population activity while male and female rats learned to associate three discrete auditory cues to three distinct outcomes: reward, punishment, or no outcome within the same session. |
2024-10-17 |
2024-10-19 |
rat |
| Tate A Pollock, Alexander V Margetts, Samara J Vilca, Luis M Tuest. Cocaine taking and craving produce distinct transcriptional profiles in dopamine neurons. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416214. |
dopamine (da) signaling plays an essential role in reward valence attribution and in encoding the reinforcing properties of natural and artificial rewards. |
2024-10-17 |
2024-10-19 |
mouse |
| Tate A Pollock, Alexander V Margetts, Samara J Vilca, Luis M Tuest. Cocaine taking and craving produce distinct transcriptional profiles in dopamine neurons. bioRxiv : the preprint server for biology. 2024-10-17. PMID:39416214. |
drug-induced changes in gene expression are one such adaptation that can determine the activity of dopamine signaling in projection regions of the brain reward system. |
2024-10-17 |
2024-10-19 |
mouse |
| Xintong Cai, Changliang Liu, Iku Tsutsui-Kimura, Joon-Hyuk Lee, Chong Guo, Aditi Banerjee, Jinoh Lee, Ryunosuke Amo, Yudi Xie, Tommaso Patriarchi, Yulong Li, Mitsuko Watabe-Uchida, Naoshige Uchida, Pascal S Kaese. Dopamine dynamics are dispensable for movement but promote reward responses. Nature. 2024-10-16. PMID:39415006. |
dopamine dynamics are dispensable for movement but promote reward responses. |
2024-10-16 |
2024-10-19 |
Not clear |
| Karin Ademar, Lisa Ulenius, Anna Loftén, Bo Söderpalm, Louise Adermark, Mia Ericso. Separate mechanisms regulating accumbal taurine levels during baseline conditions and following ethanol exposure in the rat. Scientific reports. vol 14. issue 1. 2024-10-15. PMID:39406746. |
ethanol-induced dopamine release in the nucleus accumbens (nac) is associated with reward and reinforcement, and for ethanol to elevate nac dopamine levels, a simultaneous increase in endogenous taurine is required within the same brain region. |
2024-10-15 |
2024-10-18 |
rat |
| Nicole Luengo, Gary S Goldfield, Ana M Obregó. Association between dopamine genes, adiposity, food addiction, and eating behavior in Chilean adult. Frontiers in nutrition. vol 11. 2024-10-10. PMID:39385779. |
a frequent consumption of high sugar/fat foods can affect dopamine signaling in the brain and cause sustained stimulation of the reward system. |
2024-10-10 |
2024-10-12 |
Not clear |
| Greg Perlman, Kenneth Wengler, Scott J Moeller, Roman Kotov, Daniel N Klein, Jodi J Weinstein, Guillermo Horga, Anissa Abi-Dargha. Association of Neuromelanin-Sensitive MRI Signal With Lifetime Substance Use in Young Women. The American journal of psychiatry. 2024-10-09. PMID:39380373. |
whether midbrain dopamine function is associated with substance use frequency and severity or reward function in 20-24 year-olds remains a critical gap in knowledge. |
2024-10-09 |
2024-10-11 |
Not clear |
| Maximilian Tufvesson-Alm, Cajsa Aranäs, Sebastian Blid Sköldheden, Jesper Vestlund, Christian E Edvardsson, Elisabet Jerlha. LEAP2, a ghrelin receptor inverse agonist, and its effect on alcohol-related responses in rodents. Translational psychiatry. vol 14. issue 1. 2024-10-02. PMID:39358354. |
into the third ventricle) prevented the ability of alcohol to cause locomotor stimulation in male mice, suppressed the memory of alcohol reward and attenuated the dopamine release in the nucleus accumbens caused by alcohol. |
2024-10-02 |
2024-10-05 |
mouse |