| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
surprisingly, 3) post-devaluation reconditioning, by additional pairing of cs with devalued reward, rapidly reinstated cs-induced dopamine signals to pre-devaluation levels. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
taken together, we identify distinct, divergent adaptations in dopamine-signal magnitude when reward value is decreased: cs dopamine diminishes but reinstates fast, whereas reward dopamine is resistant to change. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
this implies that, respective to above-mentioned findings, 1) cs dopamine may be governed by a model-based mechanism, and 2) reward dopamine by a model-free one, where 3) the latter may contribute to swift reinstatement of the former. |
2024-06-25 |
2024-06-29 |
rat |
| Rhiannon Robke, Tara Arbab, Rachel Smith, Ingo Willuh. Value-driven adaptations of mesolimbic dopamine release are governed by both model-based and model-free mechanisms. eNeuro. 2024-06-25. PMID:38918053. |
however, changes in cs dopamine were not selective for sensory-specificity of reward devaluation, which is inconsistent with model-based processes. |
2024-06-25 |
2024-06-29 |
rat |
| Stephanie M Matt, Rachel Nolan, Samyuktha Manikandan, Yash Agarwal, Breana Channer, Oluwatofunmi Oteju, Marzieh Daniali, Joanna A Canagarajah, Teresa LuPone, Krisna Mompho, Kaitlyn Runner, Emily Nickoloff-Bybel, Benjamin Li, Meng Niu, Johannes C M Schlachetzki, Howard S Fox, Peter J Gaskil. Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIV. bioRxiv : the preprint server for biology. 2024-06-25. PMID:38915663. |
the catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (cns) functions such as reward, movement, and cognition. |
2024-06-25 |
2024-06-27 |
human |
| Nick Augustat, Dominik Endres, Erik M Muelle. Uncertainty of treatment efficacy moderates placebo effects on reinforcement learning. Scientific reports. vol 14. issue 1. 2024-06-22. PMID:38909105. |
moreover, experiments in humans and animals indicate that reward uncertainty increases striatal dopamine, which is presumably involved in placebo responses and reward learning. |
2024-06-22 |
2024-06-25 |
human |
| Jihui Dong, Xiaoyan Wei, Ziran Huang, Jing Tian, Wen Zhan. Age-related changes of dopamine D1 and D2 receptors expression in parvalbumin-positive cells of the orbitofrontal and prelimbic cortices of mice. Frontiers in neuroscience. vol 18. 2024-06-21. PMID:38903598. |
dopamine (da) plays a pivotal role in reward processing, cognitive functions, and emotional regulation. |
2024-06-21 |
2024-06-23 |
mouse |
| Matthew R Kleinman, David J Foste. Spatial localization of hippocampal replay requires dopamine signaling. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895442. |
here we combined chemogenetic silencing of dopamine neurons in ventral tegmental area (vta) and simultaneous electrophysiological recordings in dorsal hippocampal ca1, in freely behaving rats experiencing changes to reward magnitude and environmental novelty. |
2024-06-19 |
2024-06-21 |
rat |
| Damian M Herz, Michael J Frank, Huiling Tan, Sergiu Gropp. Subthalamic control of impulsive actions: insights from deep brain stimulation in Parkinson's disease. Brain : a journal of neurology. 2024-06-13. PMID:38869168. |
while subthalamic deep brain stimulation renders patients susceptible to making decisions without proper forethought, this can be disentangled from effects related to dopamine comprising sensitivity to benefits vs. costs, reward delay aversion and learning from outcomes. |
2024-06-13 |
2024-06-15 |
human |
| Annaelle Zietz, Josefin E Kaufmann, Karin Wiesner, Sandro Kevin Fischer, Martina Wiegert, Wilma Dj Verhagen-Kamerbeek, Yannik Rottenberger, Anne Schwarz, Nils Peters, Henrik Gensicke, Friedrich Medlin, Jens Carsten Möller, Bartosz Bujan, Leo H Bonati, Marcel Arnold, Sabine Schaedelin, René M Müri, Lars G Hemkens, Patrik Michel, Philippe A Lyrer, Jeremia P Held, Gary A Ford, Andreas R Luft, Christopher Traenka, Stefan T Engelte. Enhancement of STroke REhabilitation with Levodopa (ESTREL): Rationale and design of a randomized placebo-controlled, double blind superiority trial. European stroke journal. 2024-06-10. PMID:38853524. |
dopamine is a neurotransmitter involved in motor learning, reward, and brain plasticity. |
2024-06-10 |
2024-06-14 |
Not clear |
| Collin M Lehmann, Nora E Miller, Varun S Nair, Kauê M Costa, Geoffrey Schoenbaum, Khaled Moussaw. Generalized cue reactivity in dopamine neurons after opioids. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853878. |
the leading hypothesis is that dopamine release by addictive drugs represents a persistently positive reward prediction error that causes runaway enhancement of dopamine responses to drug cues, leading to their pathological overvaluation compared to non-drug reward alternatives. |
2024-06-10 |
2024-06-14 |
Not clear |
| Collin M Lehmann, Nora E Miller, Varun S Nair, Kauê M Costa, Geoffrey Schoenbaum, Khaled Moussaw. Generalized cue reactivity in dopamine neurons after opioids. bioRxiv : the preprint server for biology. 2024-06-10. PMID:38853878. |
here we developed pavlovian and operant procedures to measure firing responses, within the same dopamine neurons, to drug versus natural reward cues, which we found to be similarly enhanced compared to cues predicting natural rewards in drug-naïve controls. |
2024-06-10 |
2024-06-14 |
Not clear |
| Mackenzie M Spicer, Matthew A Weber, Zili Luo, Jianqi Yang, Nandakumar S Narayanan, Rory A Fishe. Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse. Psychopharmacology. 2024-06-10. PMID:38856764. |
regulator of g protein signaling 6 (rgs6) in dopamine neurons promotes etoh seeking, behavioral reward, and susceptibility to relapse. |
2024-06-10 |
2024-06-14 |
Not clear |
| Mackenzie M Spicer, Matthew A Weber, Zili Luo, Jianqi Yang, Nandakumar S Narayanan, Rory A Fishe. Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse. Psychopharmacology. 2024-06-10. PMID:38856764. |
mesolimbic dopamine (da) transmission is believed to play a critical role in mediating reward responses to drugs of abuse, including alcohol (etoh). |
2024-06-10 |
2024-06-14 |
Not clear |
| Tousif Jamal, Xuan Yan, Angelica da Silva Lantyer, Judith G Ter Horst, Tansu Celike. Experience-dependent regulation of dopaminergic signaling in the somatosensory cortex. Progress in neurobiology. 2024-06-04. PMID:38834131. |
dopamine critically influences reward processing, sensory perception, and motor control. |
2024-06-04 |
2024-06-07 |
human |
| Eric Garr, Yifeng Cheng, Huijeong Jeong, Sara Brooke, Laia Castell, Aneesh Bal, Robin Magnard, Vijay Mohan K Namboodiri, Patricia H Jana. Mesostriatal dopamine is sensitive to changes in specific cue-reward contingencies. Science advances. vol 10. issue 22. 2024-05-29. PMID:38809978. |
conditioned responding was attenuated for the cue-reward contingency that was degraded, as was dopamine neuron activity in the midbrain and dopamine release in the ventral striatum in response to the cue and subsequent reward. |
2024-05-29 |
2024-06-02 |
rat |
| Fulvio Lauretani, Francesco Giallauria, Crescenzo Testa, Claudia Zinni, Beatrice Lorenzi, Irene Zucchini, Marco Salvi, Raffaele Napoli, Marcello Giuseppe Maggi. Dopamine Pharmacodynamics: New Insights. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791331. |
dopamine is a key neurotransmitter involved in physiological processes such as motor control, motivation, reward, cognitive function, and maternal and reproductive behaviors. |
2024-05-25 |
2024-05-27 |
human |
| Fulvio Lauretani, Francesco Giallauria, Crescenzo Testa, Claudia Zinni, Beatrice Lorenzi, Irene Zucchini, Marco Salvi, Raffaele Napoli, Marcello Giuseppe Maggi. Dopamine Pharmacodynamics: New Insights. International journal of molecular sciences. vol 25. issue 10. 2024-05-25. PMID:38791331. |
dopamine, via different circuitries implicated in compulsive behavior, reward, and habit formation, also represents a key player in substance use disorder and the formation and perpetuation of mechanisms leading to addiction. |
2024-05-25 |
2024-05-27 |
human |
| Susanne E la Fleur, Aurea S Blancas-Velazquez, Dirk Jan Stenvers, Andries Kalsbee. Circadian influences on feeding behavior. Neuropharmacology. 2024-05-25. PMID:38795953. |
however the scn projects only indirectly to the different reward regions, such as the ventral tegmental area where dopamine neurons are located. |
2024-05-25 |
2024-05-31 |
human |
| Kenneth Blum, David Baron, Thomas McLaughlin, Panayotis K Thanos, Catherine Dennen, Mauro Ceccanti, Eric R Braverman, Alireza Sharafshah, Kai-Uwe Lewandrowski, John Giordano, Rajendra D Badgaiya. Summary Document Research on RDS Anti-addiction Modeling: Annotated Bibliography. Journal of addiction psychiatry. vol 8. issue 1. 2024-05-21. PMID:38765881. |
further research is required to encourage the field to consider "reward deficiency syndrome (rds) anti-addiction modeling" which involves early risk identification by means of genetic assessment similar to gars, followed by induction of dopamine homeostasis by means of genetically guided pro-dopamine regulation similar to kb220. |
2024-05-21 |
2024-05-27 |
Not clear |