| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samuel J Gershman, Armin La. Policy complexity suppresses dopamine responses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2025-01-09. PMID:39788740. |
in support of this hypothesis, we find that policy complexity suppresses midbrain dopamine responses to reward outcomes. |
2025-01-09 |
2025-01-13 |
mouse |
| Thorsten Kahnt, Geoffrey Schoenbau. The curious case of dopaminergic prediction errors and learning associative information beyond value. Nature reviews. Neuroscience. 2025-01-08. PMID:39779974. |
however, whereas an abundance of work has now shown how well dopamine responses conform to the predictions of this hypothesis, far fewer studies have challenged its implicit assumption that dopamine is not involved in learning value-neutral features of reward. |
2025-01-08 |
2025-01-13 |
rat |
| Collin M Lehmann, Nora E Miller, Varun S Nair, Kauê M Costa, Geoffrey Schoenbaum, Khaled Moussaw. Generalized cue reactivity in rat dopamine neurons after opioids. Nature communications. vol 16. issue 1. 2025-01-02. PMID:39747036. |
here, we develop pavlovian and operant procedures in male rats to measure firing responses within the same dopamine neurons to drug versus natural reward cues, which we find to be similarly enhanced compared to cues predicting natural rewards in drug-naive controls. |
2025-01-02 |
2025-01-05 |
rat |
| Laetitia Imbert, Cécilia Neige, Maylis Dumas, Moustafa Bensafi, Nathalie Mandairon, Jérôme Bruneli. Combining pleasant Olfactory and BRAin stimulations in treatment-resistant depression (COBRA): study protocol for a randomized controlled trial. Frontiers in psychology. vol 15. 2025-01-02. PMID:39744036. |
at the neurobiological level, anhedonia has been associated with abnormal activity within the reward system, suggesting a key role for dopamine. |
2025-01-02 |
2025-01-04 |
Not clear |
| Sushruta Koppula, Nitu L Wankhede, Ashishkumar Kyada, Suhas Ballal, Renu Arya, Anurag Kumar Singh, Monica Gulati, Astha P Sute, Sanskruti N Sarode, Shruti P Polshettiwar, Vaibhav S Marde, Brijesh G Taksande, Aman B Upaganlawar, Mohammad Fareed, Milind J Umekar, Spandana Rajendra Kopalli, Mayur B Kal. The gut-brain axis: Unveiling the impact of xenobiotics on neurological health and disorders. Progress in neuro-psychopharmacology & biological psychiatry. 2024-12-28. PMID:39732317. |
xenobiotics also contribute to the pathophysiology of neurological disorders, with changes in serotonin levels linked to mood disorders and imbalances in gaba and dopamine associated with anxiety, stress, and reward pathway disorders. |
2024-12-28 |
2024-12-31 |
Not clear |
| Quézia Teixeira Rodrigues, Lucas Rios Drummond, Paulo Marcelo Andrade Lima, Frederico Sander Mansur Machado, Helton Oliveira Campos, Raphael Escorsim Szawka, Laura Hora Rios Leite, Cândido Celso Coimbr. Exercise performance effect of central dopamine is mediated by hypothalamic neuronal activation. Behavioural brain research. vol 480. 2024-12-26. PMID:39722282. |
acting centrally, dopamine has been shown to induce ergogenic effects derived from its influence on thermoregulation, motivation, reward, and motor control. |
2024-12-26 |
2024-12-29 |
rat |
| Alexis M Oppman, William J Paradee, Nandakumar S Narayanan, Young-Cho Ki. Generation and validation of a D1 dopamine receptor Flpo knock-in mouse. Journal of neuroscience methods. 2024-12-19. PMID:39701542. |
dopamine is a powerful neuromodulator of diverse brain functions, including movement, motivation, reward, and cognition. |
2024-12-19 |
2024-12-22 |
mouse |
| Dooti Kundu, Srijan Acharya, Shujie Wang, Yongkai Cao, Hee Jin Kim, Jae Hoon Cheong, Kyeong-Man Ki. Roles of metabotropic signaling of nicotine receptors in the development and maintenance of nicotine reward through regulation of dopamine D Journal of neurochemistry. vol 169. issue 1. 2024-12-19. PMID:39696743. |
roles of metabotropic signaling of nicotine receptors in the development and maintenance of nicotine reward through regulation of dopamine d the α4β2 nicotinic acetylcholine receptor (nachr), an ionophore, has been suggested to signal through metabotropic pathways and interact with other receptor families, such as dopamine receptors. |
2024-12-19 |
2024-12-21 |
rat |
| Myrela Ribeiro Teixeira, Tamara Silva, Rafaela de Freitas Martins Felício, Patrícia Torres Bozza, Verônica Marques Zembrzuski, Cicero Brasileiro de Mello Neto, Ana Carolina Proença da Fonseca, Fabiana Barzotto Kohlrausch, Kaio Cezar Rodrigues Salu. Exploring the Genetic Contribution in Obesity: an overview of dopaminergic system genes. Behavioural brain research. 2024-12-17. PMID:39689745. |
various neurotransmitters play an essential role in regulating food intake, such as dopamine which controls through mesolimbic circuits in the brain that modulate food reward. |
2024-12-17 |
2024-12-21 |
Not clear |
| Myrela Ribeiro Teixeira, Tamara Silva, Rafaela de Freitas Martins Felício, Patrícia Torres Bozza, Verônica Marques Zembrzuski, Cicero Brasileiro de Mello Neto, Ana Carolina Proença da Fonseca, Fabiana Barzotto Kohlrausch, Kaio Cezar Rodrigues Salu. Exploring the Genetic Contribution in Obesity: an overview of dopaminergic system genes. Behavioural brain research. 2024-12-17. PMID:39689745. |
appetite stimulation, including primary reinforcers such as food, leads to an increase in dopamine release in the reward centers of the brain. |
2024-12-17 |
2024-12-21 |
Not clear |
| Chao Gu, Yu-Chang Geng, Li-Na Zh. Dysregulation of dopamine neurotransmission in drug addicts: implications for criminal behavior and corrective interventions. Frontiers in psychiatry. vol 15. 2024-12-10. PMID:39655202. |
substances such as heroin, morphine, methamphetamine and other drugs can cause abnormal dopamine secretion when people are addicted to them, which promotes changes in the brain's reward circuit and emotional balance, thereby increasing susceptibility to criminal behavior. |
2024-12-10 |
2024-12-12 |
Not clear |
| Chao Gu, Yu-Chang Geng, Li-Na Zh. Dysregulation of dopamine neurotransmission in drug addicts: implications for criminal behavior and corrective interventions. Frontiers in psychiatry. vol 15. 2024-12-10. PMID:39655202. |
the pivotal role of dopamine within the reward pathway and its regulatory function in emotional processes exert profound influence on behavior following drug simulation. |
2024-12-10 |
2024-12-12 |
Not clear |
| Juan Enriquez-Traba, Miguel Arenivar, Hector E Yarur-Castillo, Chloe Noh, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Huikun Wang, Valerie S Tsai, Damien Kerspern, Amy E Moritz, David R Sibley, Andrew Lutas, Rosario Moratalla, Zachary Freyberg, Hugo A Tejed. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. Nature neuroscience. 2024-12-09. PMID:39653808. |
dopamine (da) release in striatal circuits, including the nucleus accumbens medial shell (mnacsh), tracks separable features of reward like motivation and reinforcement. |
2024-12-09 |
2024-12-12 |
mouse |
| Zeynep Kalaycıoğlu, Defne Bile. Capillary Electrophoresis-Frontal Analysis (CE-FA) and Molecular Docking Studies on the Albumin-Binding Properties of Dopamine and Serotonin. Journal of separation science. vol 47. issue 23. 2024-12-03. PMID:39623556. |
dopamine and serotonin are neurotransmitters that are crucial for numerous physiological processes, including mood regulation, reward, and motor function. |
2024-12-03 |
2024-12-06 |
cattle |
| Edward Justin Modestino, Abdalla Bowirrat, David Baron, Panayotis K Thanos, Colin Hanna, Debasis Bagchi, Eric R Braverman, Catherine A Dennen, Rajendra D Badgaiyan, Aryeh R Pollack, Kai-Uwe Lewandrowski, Alireza Sharafshah, Mark S Gold, Kenneth Blu. Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 Analogs. Journal of addiction psychiatry. vol 8. issue 1. 2024-12-02. PMID:39618491. |
we suggest that kb220 (and its variants) demonstrate superiority over glp-1 analogs for addressing all these issues, as evidenced by various reasons outlined herein, particularly their impact on the brain's reward cascade and dopamine homeostasis, all while avoiding antagonism of the reward system. |
2024-12-02 |
2024-12-06 |
Not clear |
| Zhigang Chen, Shaoyi Duan, Jialu Li, Jianming Su, Hongyu Le. T-2 toxin triggers depression-like behaviors via upregulation of dopamine transporter in nucleus accumbens of male mice. Ecotoxicology and environmental safety. vol 289. 2024-12-01. PMID:39616663. |
in addition, the reduced dopamine (da) level and elevated dopamine transporter (dat) level were found in reward center nucleus accumbens (nac) receiving daergic projection from ventral tegmental area (vta) in brain after t-2 toxin administration, while there was no significant alteration in da synthesis-related tyrosine hydroxylase (th) and aromatic l-amino acid decarboxylase (aadc) in vta and da storage-related vesicle monoamine transporter 2 (vmat2) in nac. |
2024-12-01 |
2024-12-06 |
mouse |
| Refugio Cruz-Trujillo, Daniel Díaz-Urbina, José Alfredo Díaz-Gandarilla, Dolores Guadalupe Vidal-López, Rodrigo Erick Escartín-Pérez, Juan Manuel Mancilla-Diaz, Benjamín Florán, Juan Gabriel Tejas-Juáre. Stimulation of Dopamine D4 Receptors in the Nucleus Accumbens Shell Increases Palatable Food Intake in Satiated Male Rats: Modulation by NMDA and AMPA Receptors. Brain sciences. vol 14. issue 11. 2024-11-27. PMID:39595865. |
the nucleus accumbens (nac) plays a central role in this process, modulating reward mechanisms primarily via dopamine through d2-like receptors (d2r, d3r, d4r). |
2024-11-27 |
2024-11-29 |
rat |
| Marialuisa de Ceglia, Adele Romano, Maria Vittoria Micioni Di Bonaventura, Ana Gavito, Luca Botticelli, Emanuela Micioni Di Bonaventura, Marzia Friuli, Carlo Cifani, Fernando Rodríguez de Fonseca, Silvana Gaetan. Cafeteria Diet Abstinence Induces Depressive Behavior and Disrupts Endocannabinoid Signaling in Dopaminergic Areas: A Preclinical Study. Current neuropharmacology. 2024-11-25. PMID:39582223. |
alterations of dopamine (da) transmission in the brain reward system can be associated with an addictive-like state defined as food addiction (fa), common in obese individuals. |
2024-11-25 |
2024-11-27 |
human |
| Bianca A Schuster, Claus Lam. How dopamine shapes trust beliefs. Progress in neuro-psychopharmacology & biological psychiatry. 2024-11-25. PMID:39586370. |
research findings strongly suggest a conceptual shift, from dopamine as a reward mechanism to a teaching signal indicating which information is relevant for learning, and shed light on the neurocomputational mechanisms via which antipsychotics may alleviate symptoms of aberrant social learning processes such as persecutory delusions. |
2024-11-25 |
2024-11-28 |
Not clear |
| John P Grogan, Matthias Raemaekers, Maaike M H van Swieten, Alexander L Green, Martin J Gillies, Sanjay G Manoha. Muscarinic receptors mediate motivation via preparatory neural activity in humans. eLife. vol 13. 2024-11-20. PMID:39565722. |
reward and dopamine make us more ready to respond, as indexed by reaction times (rt), and move faster, sometimes termed vigour. |
2024-11-20 |
2024-11-23 |
human |