| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joshua W Buckholtz, Michael T Treadway, Ronald L Cowan, Neil D Woodward, Stephen D Benning, Rui Li, M Sib Ansari, Ronald M Baldwin, Ashley N Schwartzman, Evan S Shelby, Clarence E Smith, David Cole, Robert M Kessler, David H Zal. Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits. Nature neuroscience. vol 13. issue 4. 2010-04-22. PMID:20228805. |
these findings suggest that neurochemical and neurophysiological hyper-reactivity of the dopaminergic reward system may comprise a neural substrate for impulsive-antisocial behavior and substance abuse in psychopathy. |
2010-04-22 |
2023-08-12 |
Not clear |
| Xingu He, Lin Xiao, Nan Su. Effects of SCH23390 and spiperone administered into medial striatum and intermediate medial mesopallium on rewarding effects of morphine in day-old chicks. European journal of pharmacology. vol 627. issue 1-3. 2010-04-05. PMID:19878668. |
however, it is not yet clear whether the dopaminergic system of these regions is responsible for associative learning underlying cue-elicited drug reward. |
2010-04-05 |
2023-08-12 |
Not clear |
| K Wu, M Politis, P Piccin. Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management. Postgraduate medical journal. vol 85. issue 1009. 2010-03-12. PMID:19892894. |
the pathophysiology of underlying mechanisms is not fully understood, but recent evidence suggests that dopaminergic drugs, particularly dopamine agonists, coupled with changes in reward pathways involving the ventral striatal and related circuitry, may play a role. |
2010-03-12 |
2023-08-12 |
Not clear |
| A Michaeli, R Yak. Dopamine inhibits GABA(A) currents in ventral tegmental area dopamine neurons via activation of presynaptic G-protein coupled inwardly-rectifying potassium channels. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19944748. |
dopamine (da) neurons in the ventral tegmental area (vta) constitute the origin of major dopaminergic neural pathways associated with essential functions including reward, motivation and cognition. |
2010-03-12 |
2023-08-12 |
rat |
| Natsuko Tsujino, Takeshi Sakura. Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system. Pharmacological reviews. vol 61. issue 2. 2010-03-05. PMID:19549926. |
orexin neurons also have a link with the dopaminergic reward system in the ventral tegmental nucleus. |
2010-03-05 |
2023-08-12 |
Not clear |
| Anna Machoy-Mokrzyńska, Krzysztof Borowiak, Monika Białeck. [Molecular and neuronal mechanisms of drug addiction]. Annales Academiae Medicae Stetinensis. vol 53 Suppl 2. 2010-03-05. PMID:20143672. |
considering the mechanisms of the formation of addictions recent research draws attention not only to the neuronal role of mezolimbical dopaminergic transmition, but also to the anatomical ground which is the limbic system (localization of the reward system) in the addiction progress. |
2010-03-05 |
2023-08-12 |
human |
| Eric Stice, Alain Daghe. Genetic variation in dopaminergic reward in humans. Forum of nutrition. vol 63. 2010-03-04. PMID:19955785. |
genetic variation in dopaminergic reward in humans. |
2010-03-04 |
2023-08-12 |
Not clear |
| A Castillo-Ruiz, J P Nixon, L Smale, A A Nune. Neural activation in arousal and reward areas of the brain in day-active and night-active grass rats. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19837140. |
we also measured fos expression in dopaminergic and non-dopaminergic cells of two components of the reward system that also participate in arousal - the ventral tegmental area (vta) and supramammillary nucleus (sum). |
2010-02-24 |
2023-08-12 |
human |
| J Ng, A J Rashid, C H So, B F O'Dowd, S R Georg. Activation of calcium/calmodulin-dependent protein kinase IIalpha in the striatum by the heteromeric D1-D2 dopamine receptor complex. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19837142. |
the identification of this novel mechanism by which dopamine may modulate synaptic plasticity has implications for our understanding of striatal-mediated reward and motor function, as well as neuronal disorders in which striatal dopaminergic neurotransmission is involved. |
2010-02-24 |
2023-08-12 |
Not clear |
| Michael J Frank, D James Surmeie. Do substantia nigra dopaminergic neurons differentiate between reward and punishment? Journal of molecular cell biology. vol 1. issue 1. 2010-02-18. PMID:19770170. |
do substantia nigra dopaminergic neurons differentiate between reward and punishment? |
2010-02-18 |
2023-08-12 |
Not clear |
| Michael J Frank, D James Surmeie. Do substantia nigra dopaminergic neurons differentiate between reward and punishment? Journal of molecular cell biology. vol 1. issue 1. 2010-02-18. PMID:19770170. |
the activity of dopaminergic neurons are thought to be increased by stimuli that predict reward and decreased by stimuli that predict aversive outcomes. |
2010-02-18 |
2023-08-12 |
Not clear |
| D A Peterson, C Elliott, D D Song, S Makeig, T J Sejnowski, H Poizne. Probabilistic reversal learning is impaired in Parkinson's disease. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19628022. |
collectively, the results implicate the nigral dopaminergic system in learning to make choices in environments with probabilistic and dynamic reward contingencies. |
2010-02-12 |
2023-08-12 |
human |
| Samuel D Gale, David J Perke. A basal ganglia pathway drives selective auditory responses in songbird dopaminergic neurons via disinhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089911. |
dopaminergic neurons in mammals respond to rewards and reward-predicting cues, and are thought to play an important role in learning actions or sensory cues that lead to reward. |
2010-02-05 |
2023-08-12 |
Not clear |
| Martin Darvas, Richard D Palmite. Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 3. 2010-02-05. PMID:20089924. |
dopaminergic projections to the ventral and dorsomedial striatum are important for reward, motivation, and goal-directed learning, whereas projections to the dorsolateral striatum are implicated in motor control, habitual enactment of motor skills, visuospatial learning, and memory. |
2010-02-05 |
2023-08-12 |
mouse |
| Alan C Swan. Impulsivity in mania. Current psychiatry reports. vol 11. issue 6. 2010-02-02. PMID:19909671. |
manic individuals have abnormal dopaminergic reactions to reward and abnormal responses in the ventral prefrontal cortex that are consistent with impulsive behavior. |
2010-02-02 |
2023-08-12 |
Not clear |
| Valtteri Kaasinen, Jukka Halme, Hannu Alh. [Neurobiology of pathological gambling]. Duodecim; laaketieteellinen aikakauskirja. vol 125. issue 19. 2010-01-26. PMID:19938411. |
an essential factor affecting the genesis of pathological gambling is a dysfunction of the dopaminergic reward system. |
2010-01-26 |
2023-08-12 |
Not clear |
| Julien Vezoli, Emmanuel Procy. Frontal feedback-related potentials in nonhuman primates: modulation during learning and under haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016082. |
feedback monitoring and adaptation of performance involve a medial reward system including medial frontal cortical areas, the medial striatum, and the dopaminergic system. |
2010-01-26 |
2023-08-12 |
monkey |
| Christopher A Deister, Mark A Teagarden, Charles J Wilson, Carlos A Paladin. An intrinsic neuronal oscillator underlies dopaminergic neuron bursting. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016105. |
dopaminergic neurons of the ventral midbrain fire high-frequency bursts when animals are presented with unexpected rewards, or stimuli that predict reward. |
2010-01-26 |
2023-08-12 |
Not clear |
| Thilo van Eimeren, Bénédicte Ballanger, Giovanna Pellecchia, Janis M Miyasaki, Anthony E Lang, Antonio P Strafell. Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 13. 2010-01-19. PMID:19741594. |
we tested the hypothesis that tonic stimulation of dopamine receptors specifically desensitizes the dopaminergic reward system by preventing decreases in dopaminergic transmission that occurs with negative feedback. |
2010-01-19 |
2023-08-12 |
Not clear |
| Rex M Philpot, Lynn Wecker, Cheryl L Kirstei. Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 27. issue 8. 2010-01-15. PMID:19712739. |
the nucleus accumbens septi undergoes dramatic developmental transitions during the adolescent period, and dopaminergic activity within this region has been identified as a central neurochemical mediator of drug reward, addiction and dependence. |
2010-01-15 |
2023-08-12 |
rat |