| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christian Brabant, Livia Alleva, Etienne Quertemont, Ezio Tirell. Involvement of the brain histaminergic system in addiction and addiction-related behaviors: a comprehensive review with emphasis on the potential therapeutic use of histaminergic compounds in drug dependence. Progress in neurobiology. vol 92. issue 3. 2011-02-28. PMID:20638439. |
pharmacological and brain lesion experiments initially led to the proposition that the histaminergic system exerts an inhibitory influence on drug reward processes, opposed to that of the dopaminergic system. |
2011-02-28 |
2023-08-12 |
Not clear |
| Sophie Bayard, Huan Yu, Muriel Croisier Langenier, Bertrand Carlander, Yves Dauvillier. Decision making in restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 15. 2011-02-25. PMID:20669306. |
rls provides an opportunity to test the dopaminergic hypothesis in a drug-free population and to characterize reward processing using decision-making paradigms. |
2011-02-25 |
2023-08-12 |
human |
| Estela Camara, Ulrike M Krämer, Toni Cunillera, Josep Marco-Pallarés, David Cucurell, Wido Nager, Anna Mestres-Missé, Peter Bauer, Rebecca Schüle, Ludger Schöls, Claus Tempelmann, Antoni Rodriguez-Fornells, Thomas F Münt. The effects of COMT (Val108/158Met) and DRD4 (SNP -521) dopamine genotypes on brain activations related to valence and magnitude of rewards. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 8. 2011-02-18. PMID:20038544. |
these findings emphasize the differential contribution of genetic variants in the dopaminergic system to various aspects of reward processing. |
2011-02-18 |
2023-08-12 |
human |
| David K Miller, Abdalla Bowirrat, Matthew Manka, Merlene Miller, Stanley Stokes, Debra Manka, Cameron Allen, Charles Gant, B William Downs, Andrew Smolen, Emily Stevens, Swetha Yeldandi, Kenneth Blu. Acute intravenous synaptamine complex variant KB220™ "normalizes" neurological dysregulation in patients during protracted abstinence from alcohol and opiates as observed using quantitative electroencephalographic and genetic analysis for reward polymorphisms: part 1, pilot study with 2 case reports. Postgraduate medicine. vol 122. issue 6. 2011-02-14. PMID:21084795. |
both patients were genotyped for a number of neurotransmitter reward genes to determine to what extent they carry putative dopaminergic risk alleles that may predispose them for alcohol or heroin dependence, respectively. |
2011-02-14 |
2023-08-12 |
Not clear |
| Carsten Nicolas Boehler, Nico Bunzeck, Ruth M Krebs, Toemme Noesselt, Mircea A Schoenfeld, Hans-Jochen Heinze, Thomas F Münte, Marty G Woldorff, Jens-Max Hop. Substantia nigra activity level predicts trial-to-trial adjustments in cognitive control. Journal of cognitive neuroscience. vol 23. issue 2. 2011-02-11. PMID:20465358. |
in that dopaminergic involvement has been strongly implicated in reinforcement learning, these ideas suggest functional links between reinforcement learning, where the outcome of actions shapes behavior over time, and cognitive control in a more general context, where no direct reward is involved. |
2011-02-11 |
2023-08-12 |
Not clear |
| Carsten Nicolas Boehler, Nico Bunzeck, Ruth M Krebs, Toemme Noesselt, Mircea A Schoenfeld, Hans-Jochen Heinze, Thomas F Münte, Marty G Woldorff, Jens-Max Hop. Substantia nigra activity level predicts trial-to-trial adjustments in cognitive control. Journal of cognitive neuroscience. vol 23. issue 2. 2011-02-11. PMID:20465358. |
this link between sn activity and subsequent behavioral adjustments lends support to theoretical accounts that propose dopaminergic control signals that shape behavior both in the presence and in the absence of direct reward. |
2011-02-11 |
2023-08-12 |
Not clear |
| Gabriela Rodríguez-Manzo, Francisco Pellice. Electrical stimulation of dorsal and ventral striatum differentially alters the copulatory behavior of male rats. Behavioral neuroscience. vol 124. issue 5. 2011-02-09. PMID:20939668. |
sexual behavior is a natural reward that activates striatal dopaminergic (da) circuits, and dopamine exerts a facilitative influence on copulation. |
2011-02-09 |
2023-08-12 |
rat |
| Anne Lingford-Hughes, Ben Watson, Nicola Kalk, Alastair Rei. Neuropharmacology of addiction and how it informs treatment. British medical bulletin. vol 96. 2011-01-21. PMID:21044987. |
although the dopaminergic mesolimbic system plays a central role in 'liking', reward and motivation, medications directly targeting it have not proved a very fruitful approach to treating addictions. |
2011-01-21 |
2023-08-12 |
Not clear |
| Jessica E Sturgess, Ryan A Ting-A-Kee, Dominik Podbielski, Laurie H L Sellings, Jiang-Fan Chen, Derek van der Koo. Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20576036. |
we show that caffeine has an atypical reward mechanism, independent of the dopaminergic system and the tegmental pedunculopontine nucleus, and provide additional evidence in support of a role for the dopaminergic system in aversive learning. |
2011-01-13 |
2023-08-12 |
mouse |
| Zivjena Vucetic, Teresa M Reye. Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity. Wiley interdisciplinary reviews. Systems biology and medicine. vol 2. issue 5. 2011-01-12. PMID:20836049. |
central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity. |
2011-01-12 |
2023-08-12 |
Not clear |
| Gerard P Smith, James C Smit. The inhibitory potency of SCH 23390 and raclopride on licking for sucrose increases across brief-access tests. Physiology & behavior. vol 101. issue 3. 2011-01-05. PMID:20515702. |
one aspect of the pharmacological evidence for dopaminergic mediation of sweet reward is unclear. |
2011-01-05 |
2023-08-12 |
rat |
| Jie W. Double target concept for smoking cessation. Acta pharmacologica Sinica. vol 31. issue 9. 2011-01-04. PMID:20711220. |
through the nachrs in brain reward circuits, nicotine alters dopaminergic (da) neuronal function in the ventral tegmental area (vta) and increases dopamine release from vta to nuclear accumbens (na), which leads to nicotine reward, tolerance and dependence. |
2011-01-04 |
2023-08-12 |
Not clear |
| Jakob Linnet, E Peterson, D J Doudet, A Gjedde, A Mølle. Dopamine release in ventral striatum of pathological gamblers losing money. Acta psychiatrica Scandinavica. vol 122. issue 4. 2010-12-22. PMID:20712823. |
to investigate dopaminergic neurotransmission in relation to monetary reward and punishment in pathological gambling. |
2010-12-22 |
2023-08-12 |
Not clear |
| José Manuel Trigo, Elena Martin-García, Fernando Berrendero, Patricia Robledo, Rafael Maldonad. The endogenous opioid system: a common substrate in drug addiction. Drug and alcohol dependence. vol 108. issue 3. 2010-12-13. PMID:19945803. |
opioid receptors and endogenous opioid peptides are largely distributed in the mesolimbic system and modulate dopaminergic activity within these reward circuits. |
2010-12-13 |
2023-08-12 |
Not clear |
| Julia P Dunn, Ronald L Cowan, Nora D Volkow, Irene D Feurer, Rui Li, D Brandon Williams, Robert M Kessler, Naji N Abumra. Decreased dopamine type 2 receptor availability after bariatric surgery: preliminary findings. Brain research. vol 1350. 2010-12-06. PMID:20362560. |
diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. |
2010-12-06 |
2023-08-12 |
Not clear |
| Michele Poletti, Daniela Frosini, Claudio Lucetti, Paolo Del Dotto, Roberto Ceravolo, Ubaldo Bonuccell. Decision making in de novo Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 10. 2010-12-02. PMID:20629139. |
two principal causal hypotheses have been proposed to explain this phenomenon: the overdosing effects of dopaminergic therapy on the orbital frontostriatal circuit that is involved in reward processing, or an amygdala dysfunction, as suggested by similar skin conductance responses of patients with pd and amygdala-damaged patients while performing this task. |
2010-12-02 |
2023-08-12 |
Not clear |
| Toshihiko Aosaki, Masami Miura, Takeo Suzuki, Kinya Nishimura, Masao Masud. Acetylcholine-dopamine balance hypothesis in the striatum: an update. Geriatrics & gerontology international. vol 10 Suppl 1. 2010-10-21. PMID:20590830. |
during sensorimotor learning, the arrival of a conditioned stimulus reporting a reward evokes a pause response in the firing of the tonically active cholinergic interneurons in targeted areas of the striatum, whereas the same stimulus triggers an increase in the firing frequency of the dopaminergic neurons in the substantia nigra pars compacta. |
2010-10-21 |
2023-08-12 |
Not clear |
| Mitul A Mehta, Emma Gore-Langton, Nicole Golembo, Emma Colvert, Steven C R Williams, Edmund Sonuga-Bark. Hyporesponsive reward anticipation in the basal ganglia following severe institutional deprivation early in life. Journal of cognitive neuroscience. vol 22. issue 10. 2010-09-22. PMID:19929329. |
based on these studies and known dopaminergic abnormalities from studies in experimental animals using social isolation, we used a task of monetary reward anticipation to examine the functional integrity of brain regions previously shown to be implicated in reward processing. |
2010-09-22 |
2023-08-12 |
Not clear |
| Andreas Heinz, Florian Schlagenhau. Dopaminergic dysfunction in schizophrenia: salience attribution revisited. Schizophrenia bulletin. vol 36. issue 3. 2010-09-16. PMID:20453041. |
the dopaminergic signal has been conceptualized to represent a prediction error that indicates the difference between received and predicted reward. |
2010-09-16 |
2023-08-12 |
Not clear |
| Borwin Bandelow, Christian Schmahl, Peter Falkai, Dirk Wedekin. Borderline personality disorder: a dysregulation of the endogenous opioid system? Psychological review. vol 117. issue 2. 2010-09-14. PMID:20438240. |
the alarming symptoms and self-destructive behaviors of the affected patients may be explained by uncontrollable and unconscious attempts to stimulate their endogenous opioid system (eos) and the dopaminergic reward system, regardless of the possible harmful consequences. |
2010-09-14 |
2023-08-12 |
human |