| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Livia Tomova, Kay Tye, Rebecca Sax. The neuroscience of unmet social needs. Social neuroscience. vol 16. issue 3. 2021-06-14. PMID:31729923. |
we focus particularly on the dopaminergic reward system and try to integrate evidence from animal models and human research. |
2021-06-14 |
2023-08-13 |
human |
| Hongyu Ruan, Wei-Dong Ya. Loss of mGluR1-LTD following cocaine exposure accumulates Ca Journal of neurogenetics. 2021-06-14. PMID:34092163. |
loss of mglur1-ltd following cocaine exposure accumulates ca addiction results from drug-elicited alterations of synaptic plasticity mechanisms in dopaminergic reward circuits. |
2021-06-14 |
2023-08-13 |
Not clear |
| Yi-Ying Kuo, Jie-Kuan Lin, Ya-Tin Lin, Jin-Chung Chen, Yu-Ming Kuo, Po-See Chen, Sheng-Nan Wu, Pei-Chun Che. Glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue. Psychoneuroendocrinology. vol 118. 2021-06-04. PMID:32479969. |
glibenclamide restores dopaminergic reward circuitry in obese mice through interscauplar brown adipose tissue. |
2021-06-04 |
2023-08-13 |
mouse |
| Zoe M Lipman, Gil Yosipovitc. Substance use disorders and chronic itch. Journal of the American Academy of Dermatology. vol 84. issue 1. 2021-05-31. PMID:32891774. |
recent literature has uncovered similarities between the general neurologic mechanisms of addiction and chronic itch, largely involving activation of the dopaminergic reward circuits within the brain and imbalances between mu and kappa opioid receptor activation. |
2021-05-31 |
2023-08-13 |
Not clear |
| Sri Mahavir Agarwal, Chantel Kowalchuk, Laura Castellani, Kenya A Costa-Dookhan, Fernando Caravaggio, Roshanak Asgariroozbehani, Araba Chintoh, Ariel Graff-Guerrero, Margaret Hah. Brain insulin action: Implications for the treatment of schizophrenia. Neuropharmacology. vol 168. 2021-05-27. PMID:31152767. |
the development of central insulin resistance is associated with alterations in dopaminergic reward systems and homeostatic signals affecting food intake, glucose metabolism, body weight and cognitive performance. |
2021-05-27 |
2023-08-13 |
Not clear |
| Oliver Grimm, Magdalena Nägele, Lea Küpper-Tetzel, Moritz de Greck, Michael Plichta, Andreas Rei. No effect of a dopaminergic modulation fMRI task by amisulpride and L-DOPA on reward anticipation in healthy volunteers. Psychopharmacology. vol 238. issue 5. 2021-05-19. PMID:33140215. |
dysregulation of dopaminergic neurotransmission, specifically altered reward processing assessed via the reward anticipation in the mid task, plays a central role in the etiopathogenesis of neuropsychiatric disorders. |
2021-05-19 |
2023-08-13 |
human |
| Kenneth Blum, David Baron, Thomas McLaughlin, Mark S Gol. Molecular neurological correlates of endorphinergic/dopaminergic mechanisms in reward circuitry linked to endorphinergic deficiency syndrome (EDS). Journal of the neurological sciences. vol 411. 2021-05-14. PMID:32088516. |
the role of dopamine in terms of alcohol withdrawal symptomology, cocaine craving behavior, dopamine -condensation products (tiqs), and more recently, the genetic aspects of drug-seeking and pro-dopamine regulation, provide compelling evidence of the relevant molecular neurological correlates of dopaminergic /endorphinergic mechanisms in reward circuitry due to genetic polymorphisms and epigenetic insults. |
2021-05-14 |
2023-08-13 |
Not clear |
| Kenneth Blum, David Baron, Thomas McLaughlin, Mark S Gol. Molecular neurological correlates of endorphinergic/dopaminergic mechanisms in reward circuitry linked to endorphinergic deficiency syndrome (EDS). Journal of the neurological sciences. vol 411. 2021-05-14. PMID:32088516. |
as subsets of reward deficiency, we are poised to provide novel, genetically guided therapy for endorphinergic, opioidergic, and dopaminergic deficiencies and related syndromes, utilizing "precision addiction management. |
2021-05-14 |
2023-08-13 |
Not clear |
| Bo-Ryoung Choi, Dong-Hee Kim, Michela Gallagher, Jung-Soo Ha. Engagement of the Lateral Habenula in the Association of a Conditioned Stimulus with the Absence of an Unconditioned Stimulus. Neuroscience. vol 444. 2021-05-14. PMID:32717296. |
neurons in the lateral habenula (lhb) are activated by reward omission and inhibited by reward delivery-reward processing functions opposite those of midbrain dopaminergic neurons. |
2021-05-14 |
2023-08-13 |
rat |
| Rohini Kuner, Thomas Kune. Cellular Circuits in the Brain and Their Modulation in Acute and Chronic Pain. Physiological reviews. vol 101. issue 1. 2021-05-06. PMID:32525759. |
the review summarizes recent breakthroughs and insights on structure-function properties in nociceptive circuits and higher order sub-neocortical modulatory circuits involved in aversion, learning, reward, and mood and their modulation by endogenous gabaergic inhibition, noradrenergic, cholinergic, dopaminergic, serotonergic, and peptidergic pathways. |
2021-05-06 |
2023-08-13 |
Not clear |
| Luis A- Trujillo Villarreal, Marcela Cárdenas-Tueme, Roger Maldonado-Ruiz, Diana Reséndez-Pérez, Alberto Camacho-Morale. Potential role of primed microglia during obesity on the mesocorticolimbic circuit in autism spectrum disorder. Journal of neurochemistry. vol 156. issue 4. 2021-05-04. PMID:32902852. |
therefore, we propose that a positive energy balance during obesity/maternal overnutrition coordinates a systemic and central inflammatory crosstalk that modulates the dopaminergic neurotransmission in selective brain areas of the mesocorticolimbic reward pathway. |
2021-05-04 |
2023-08-13 |
mouse |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (danio rerio) under circumstances of motivational conflict: towards a screening test for anti-compulsive drug action. |
2021-05-03 |
2023-08-13 |
zebrafish |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
towards the development of a zebrafish (danio rerio) screening test for anti-compulsive drug action, we manipulated social reward appraisal under different contexts by means of dopaminergic (apomorphine) and serotonergic (escitalopram) intervention. |
2021-05-03 |
2023-08-13 |
zebrafish |
| C van Staden, G de Brouwer, T L Botha, K Finger-Baier, S J Brand, D Wolmaran. Dopaminergic and serotonergic modulation of social reward appraisal in zebrafish (Danio rerio) under circumstances of motivational conflict: Towards a screening test for anti-compulsive drug action. Behavioural brain research. vol 379. 2021-05-03. PMID:31785362. |
we demonstrate that 1) sight of social conspecifics is an inadequate motivational reinforcer under circumstances of motivational conflict, 2) dopaminergic and serotonergic intervention lessens the importance of an aversive stimulus, increasing the motivational valence of social reward, 3) while serotoninergic intervention maintains reward directed behavior, high-dose dopaminergic intervention bolsters cue-directed responses and 4) high-dose escitalopram reversed apomorphine-induced behavioral inflexibility. |
2021-05-03 |
2023-08-13 |
zebrafish |
| Chieh-Liang Huang, Ping-Ho Chen, Hsien-Yuan Lane, Ing-Kang Ho, Chia-Min Chun. Risk Assessment for Heroin Use and Craving Score Using Polygenic Risk Score. Journal of personalized medicine. vol 11. issue 4. 2021-05-02. PMID:33915886. |
the objective of this study was to identify heroin addicts who carry specific genetic variants in their dopaminergic reward systems. |
2021-05-02 |
2023-08-13 |
Not clear |
| Chieh-Liang Huang, Ping-Ho Chen, Hsien-Yuan Lane, Ing-Kang Ho, Chia-Min Chun. Risk Assessment for Heroin Use and Craving Score Using Polygenic Risk Score. Journal of personalized medicine. vol 11. issue 4. 2021-05-02. PMID:33915886. |
a general linear regression model was used to assess the associations of genetic polymorphisms in one's dopaminergic reward system with heroin-use and craving scores. |
2021-05-02 |
2023-08-13 |
Not clear |
| Mandakh Bekhbat, Michael T Treadway, David R Goldsmith, Bobbi J Woolwine, Ebrahim Haroon, Andrew H Miller, Jennifer C Felge. Gene signatures in peripheral blood immune cells related to insulin resistance and low tyrosine metabolism define a sub-type of depression with high CRP and anhedonia. Brain, behavior, and immunity. vol 88. 2021-04-27. PMID:32198016. |
we have previously shown that high inflammation as measured by c-reactive protein (crp) in mdd patients is associated with symptoms of anhedonia, a core symptom of mdd, along with deficits in dopaminergic reward circuitry. |
2021-04-27 |
2023-08-13 |
Not clear |
| Jodi R Godfrey, Melanie Pincus, Zsofia Kovacs-Balint, Eric Feczko, Eric Earl, Oscar Miranda-Dominguez, Damien A Fair, Sara R Jones, Jason Locke, Mar M Sanchez, Mark E Wilson, Vasiliki Michopoulo. Obesogenic diet-associated C-reactive protein predicts reduced central dopamine and corticostriatal functional connectivity in female rhesus monkeys. Brain, behavior, and immunity. vol 88. 2021-04-27. PMID:32240763. |
alterations in dopamine (da) signaling and reductions in functional connectivity (fc; a measure of temporal correlations of activity between different brain regions) within dopaminergic reward pathways are implicated in the etiology of psychopathology and have been associated with increased concentrations of inflammatory markers, including c-reactive protein. |
2021-04-27 |
2023-08-13 |
monkey |
| Tristan J Hynes, Jacqueline-Marie M Ferland, Tanya L Feng, Wendy K Adams, Mason M Silveira, Melanie Tremblay, Chloe S Chernoff, Hannah G Brodie, Sophie A Ebsary, Brittney Russell, Sukhbir Kaur, Catharine A Winstanle. Chemogenetic inhibition of dopaminergic projections to the nucleus accumbens has sexually dimorphic effects in the rat gambling task. Behavioral neuroscience. vol 134. issue 4. 2021-04-19. PMID:32525335. |
sexual dimorphisms in behavioral control by the mesolimbic dopaminergic reward system may underlie these phenomena, given its sensitivity to gonadal hormones. |
2021-04-19 |
2023-08-13 |
rat |
| Li Yan McCurdy, Preeti Sareen, Pasha A Davoudian, Michael N Nitabac. Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila. Nature communications. vol 12. issue 1. 2021-04-02. PMID:33602917. |
when a cue later occurs without punishment, this unexpected omission of aversive outcome is encoded as reward via activation of reward-encoding dopaminergic neurons. |
2021-04-02 |
2023-08-13 |
drosophila_melanogaster |