| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jakob Linne. The anticipatory dopamine response in addiction: A common neurobiological underpinning of gambling disorder and substance use disorder? Progress in neuro-psychopharmacology & biological psychiatry. vol 98. 2021-11-22. PMID:31678482. |
second, it is suggested that dopaminergic reward response may be not a common pathway, since substance use disorder is associated with a blunted dopamine response toward drugs, while conflicting findings of reward response has been reported in gambling disorder. |
2021-11-22 |
2023-08-13 |
Not clear |
| Patrick Bach, Anne Koopmann, Falk Kiefe. The Impact of Appetite-Regulating Neuropeptide Leptin on Alcohol Use, Alcohol Craving and Addictive Behavior: A Systematic Review of Preclinical and Clinical Data. Alcohol and alcoholism (Oxford, Oxfordshire). vol 56. issue 2. 2021-11-22. PMID:32490525. |
this suggests that leptin plays a role in the processing of rewards in the context of substance use disorders such as alcohol use disorder, especially through attenuation of dopaminergic activity in the mesolimbic reward system. |
2021-11-22 |
2023-08-13 |
Not clear |
| Dan P Covey, Edith Hernandez, Miguel Á Luján, Joseph F Chee. Chronic Augmentation of Endocannabinoid Levels Persistently Increases Dopaminergic Encoding of Reward Cost and Motivation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 32. 2021-11-22. PMID:34230105. |
chronic augmentation of endocannabinoid levels persistently increases dopaminergic encoding of reward cost and motivation. |
2021-11-22 |
2023-08-13 |
mouse |
| Xiaolin Tia. Enhancing mask activity in dopaminergic neurons extends lifespan in flies. Aging cell. vol 20. issue 11. 2021-11-20. PMID:34626525. |
dopaminergic neurons (dans) are essential modulators for brain functions involving memory formation, reward processing, and decision-making. |
2021-11-20 |
2023-08-13 |
Not clear |
| Sanjay N Awathale, Amit G Choudhary, Nishikant K Subhedar, Dadasaheb M Kokar. Neuropeptide CART modulates dopamine turnover in the nucleus accumbens: Insights into the anatomy of rewarding circuits. Journal of neurochemistry. vol 158. issue 5. 2021-11-17. PMID:34287909. |
neuropeptide cocaine- and amphetamine-regulated transcript (cart) is known to influence the activity of the canonical mesolimbic dopaminergic pathway and modulate reward seeking behaviour. |
2021-11-17 |
2023-08-13 |
rat |
| Robert G Lewis, Ermanno Florio, Daniela Punzo, Emiliana Borrell. The Brain's Reward System in Health and Disease. Advances in experimental medicine and biology. vol 1344. 2021-11-16. PMID:34773226. |
in this chapter, we will discuss the influence of the dopaminergic reward pathways on circadian system and the implication of this interplay on human health. |
2021-11-16 |
2023-08-13 |
human |
| Rui Zhang, Peter Manza, Dardo Tomasi, Sung Won Kim, Ehsan Shokri-Kojori, Sukru B Demiral, Danielle S Kroll, Dana E Feldman, Katherine L McPherson, Catherine L Biesecker, Gene-Jack Wang, Nora D Volko. Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward. The Journal of clinical investigation. vol 131. issue 18. 2021-11-15. PMID:34264865. |
dopaminergic (da) signaling has been hypothesized to mediate the associations, though clinical evidence is lacking.methodswe examined associations between rhythm components and striatal d1 (d1r) and d2/3 receptor (d2/3r) availability in 32 healthy adults (12 female, 20 male; age 42.40 ± 12.22 years) and its relationship to drug reward. |
2021-11-15 |
2023-08-13 |
Not clear |
| Aqilah M McCane, Meredyth A Wegener, Mojdeh Faraji, Maria T Rivera-Garcia, Kathryn G Wallin-Miller, Vincent D Costa, Bita Moghadda. Adolescent Dopamine Neurons Represent Reward Differently during Action and State Guided Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 45. 2021-11-14. PMID:34611024. |
static characteristics of dopamine neurons, such as dopamine cell number and size, were similar in the vta and sn of both ages, but there were age-related differences in stimulated dopamine release and correlated spike activity, suggesting that differences in reward responsiveness by adolescent dopamine neurons are not because of differences in intrinsic properties of these neurons but engagement of different dopaminergic networks. |
2021-11-14 |
2023-08-13 |
rat |
| Tina Kazemi, Shuyan Huang, Naze G Avci, Yasemin M Akay, Metin Aka. Investigating the effects of chronic perinatal alcohol and combined nicotine and alcohol exposure on dopaminergic and non-dopaminergic neurons in the VTA. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33888815. |
the ventral tegmental area (vta) is the origin of dopaminergic neurons and the dopamine (da) reward pathway. |
2021-11-12 |
2023-08-13 |
rat |
| Mirjam Wolfschlag, Anders Håkansso. Increased risk for developing gambling disorder under the treatment with pramipexole, ropinirole, and aripiprazole: A nationwide register study in Sweden. PloS one. vol 16. issue 6. 2021-11-12. PMID:34061895. |
gambling disorder (gd) has recently been reclassified from an impulse-control disorder to a behavioural addiction and, as in other addictive disorders, the dopaminergic reward system is involved. |
2021-11-12 |
2023-08-13 |
Not clear |
| Ming-Shuo Shao, Xiao Yang, Chen-Chun Zhang, Chang-You Jiang, Ying Mao, Wen-Dong Xu, Lan Ma, Fei-Fei Wan. O-GlcNAcylation in Ventral Tegmental Area Dopaminergic Neurons Regulates Motor Learning and the Response to Natural Reward. Neuroscience bulletin. 2021-11-06. PMID:34741260. |
o-glcnacylation in ventral tegmental area dopaminergic neurons regulates motor learning and the response to natural reward. |
2021-11-06 |
2023-08-13 |
mouse |
| Yusuf S Althobaiti, Farooq M Almutairi, Fahad S Alshehri, Ebtehal Altowairqi, Aliyah M Marghalani, Amal A Alghorabi, Walaa F Alsanie, Ahmed Gaber, Hashem O Alsaab, Atiah H Almalki, Alqassem Y Hakami, Turki Alkhalifa, Ahmad D Almalki, Ana M G Hardy, Zahoor A Sha. Involvement of the dopaminergic system in the reward-related behavior of pregabalin. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34011976. |
notably, the dopaminergic reward circuitry is also known to play a crucial role in medication-seeking behavior. |
2021-11-05 |
2023-08-13 |
mouse |
| Akira Mizoguchi, Ryoichi Banno, Runan Sun, Hiroshi Yaginuma, Keigo Taki, Tomoko Kobayashi, Mariko Sugiyama, Taku Tsunekawa, Takeshi Onoue, Hiroshi Takagi, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Hidetaka Suga, Taku Nagai, Kiyofumi Yamada, Hiroshi Arim. Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34145364. |
the reward system, which consists of dopaminergic neurons projecting from the ventral tegmental area (vta) to the nucleus accumbens and caudate-putamen in the striatum, has an important role in the pathogenesis of not only drug addiction but also diet-induced obesity. |
2021-11-05 |
2023-08-13 |
mouse |
| Nihaad Paraouty, Catherine R Rizzuto, Dan H Sane. Dopaminergic signaling supports auditory social learning. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34162951. |
to test whether a dopaminergic signal was sufficient to enhance social learning, we administered a d1/d5 receptor agonist during the exposure sessions in which no reward was present and found that the rate of learning occurred significantly faster. |
2021-11-05 |
2023-08-13 |
Not clear |
| Warren D Taylor, David H Zald, Jennifer C Felger, Seth Christman, Daniel O Claassen, Guillermo Horga, Jeffrey M Miller, Katherine Gifford, Baxter Rogers, Sarah M Szymkowicz, Bret R Rutherfor. Influences of dopaminergic system dysfunction on late-life depression. Molecular psychiatry. 2021-11-05. PMID:34404915. |
we propose a unified model incorporating the effects of aging and low-grade inflammation on dopaminergic functioning, with a resulting negative effect on cognition, reward processing, and motor function. |
2021-11-05 |
2023-08-13 |
Not clear |
| Krzysztof Chmielowiec, Monika Michałowska-Sawczyn, Jolanta Masiak, Jolanta Chmielowiec, Grzegorz Trybek, Marta Niewczas, Wojciech Czarny, Paweł Cieszczyk, Myosotis Massidda, Patrizia Proia, Anna Grzywac. Analysis of DRD2 Gene Polymorphism in the Context of Personality Traits in a Group of Athletes. Genes. vol 12. issue 8. 2021-11-05. PMID:34440393. |
in the studied athletes, the features related to reward addiction and harm avoidance are particularly important in connection with the dopaminergic reward system in the brain. |
2021-11-05 |
2023-08-13 |
human |
| Brant P Hasler, Colleen A McClun. Delayed circadian rhythms and substance abuse: dopamine transmission's time has come. The Journal of clinical investigation. vol 131. issue 18. 2021-11-05. PMID:34523611. |
human studies that investigate relationships between sleep, circadian rhythm, and substance use reward generally rely on indirect means to infer dopaminergic function, such as functional magnetic resonance imaging. |
2021-11-05 |
2023-08-13 |
human |
| Kenneth Blum, Thomas McLaughlin, Edward J Modestino, David Baron, Abdalla Bowirrat, Raymond Brewer, Bruce Steinberg, A Kenison Roy, Marcello Febo, Rajendra D Badgaiyan, Marks S Gol. Epigenetic Repair of Terrifying Lucid Dreams by Enhanced Brain Reward Functional Connectivity and Induction of Dopaminergic Homeostatic Signaling. Current psychopharmacology. vol 10. 2021-10-30. PMID:34707968. |
epigenetic repair of terrifying lucid dreams by enhanced brain reward functional connectivity and induction of dopaminergic homeostatic signaling. |
2021-10-30 |
2023-08-13 |
Not clear |
| Leonardo Bontempi, Antonello Bonc. µ-Opioid receptor-induced synaptic plasticity in dopamine neurons mediates the rewarding properties of anabolic androgenic steroids. Science signaling. vol 13. issue 647. 2021-10-29. PMID:32873724. |
these data suggest that aas indirectly stimulate a dopaminergic reward center of the brain through activation of endogenous opioid signaling and that this mechanism mediates the addictive effects of aas. |
2021-10-29 |
2023-08-13 |
mouse |
| Marjan Alizadeh Asfestani, Valentin Brechtmann, João Santiago, Andreas Peter, Jan Born, Gordon Benedikt Fel. Consolidation of Reward Memory during Sleep Does Not Require Dopaminergic Activation. Journal of cognitive neuroscience. vol 32. issue 9. 2021-10-28. PMID:32459129. |
consolidation of reward memory during sleep does not require dopaminergic activation. |
2021-10-28 |
2023-08-13 |
human |