| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R R Miller, E A Hermann, J T Young, L L Calhoun, P E Kast. Propylene glycol monomethyl ether acetate (PGMEA) metabolism, disposition, and short-term vapor inhalation toxicity studies. Toxicology and applied pharmacology. vol 75. issue 3. 1984-10-25. PMID:6474479. |
however, histopathologic examination did reveal changes in the olfactory portions of the nasal mucosa of rats and mice exposed to pgmea, which may be related to acetic acid resulting from hydrolysis of pgmea in the nasal epithelium. |
1984-10-25 |
2023-08-12 |
mouse |
| T Nakashima, C P Kimmelman, J B Sno. Structure of human fetal and adult olfactory neuroepithelium. Archives of otolaryngology (Chicago, Ill. : 1960). vol 110. issue 10. 1984-10-24. PMID:6477257. |
in the fetus, the olfactory neuroepithelium extends from the roof of the nasal cavity to the midportion of the nasal septum and onto the superior turbinate in a continuous fashion. |
1984-10-24 |
2023-08-12 |
human |
| C L Moor. Maternal contributions to the development of masculine sexual behavior in laboratory rats. Developmental psychobiology. vol 17. issue 4. 1984-08-31. PMID:6745497. |
maternal licking was manipulated by lining the nasal passages of rat dams with polyethylene tubing to interfere with their olfactory competence. |
1984-08-31 |
2023-08-12 |
rat |
| E B Brittebo, M Ahlma. Metabolism of a nasal carcinogen, phenacetin, in the mucosa of the upper respiratory tract. Chemico-biological interactions. vol 50. issue 2. 1984-08-24. PMID:6744467. |
microautoradiography showed that tissue-bound radioactivity was present in the epithelium of the nasal and tracheo-bronchial mucosa and in subepithelial glands in the olfactory mucosa. |
1984-08-24 |
2023-08-12 |
rat |
| M P Schreibman, H Margolis-Kazan, L Halpern-Sebold, P A O'Neill, R C Silverma. Structural and functional links between olfactory and reproductive systems: puberty-related changes in olfactory epithelium. Brain research. vol 302. issue 1. 1984-08-20. PMID:6375812. |
the structural and functional link between olfactory reproductive systems in male and female platyfish (xiphophorus maculatus) is demonstrated by the connection of receptors in the nasal epithelium to a center in the brain that has a primary role in the development and functioning of the reproductive system. |
1984-08-20 |
2023-08-12 |
Not clear |
| M P Schreibman, H Margolis-Kazan, L Halpern-Sebold, P A O'Neill, R C Silverma. Structural and functional links between olfactory and reproductive systems: puberty-related changes in olfactory epithelium. Brain research. vol 302. issue 1. 1984-08-20. PMID:6375812. |
profound morphological changes occur in the nasal epithelium, and lh-rh content increases in tracts of the olfactory lobe, at specific stages of sexual maturation and not according to chronological age. |
1984-08-20 |
2023-08-12 |
Not clear |
| E B Brittebo, J J Rafte. Steroid metabolism by rat nasal mucosa: studies on progesterone and testosterone. Journal of steroid biochemistry. vol 20. issue 5. 1984-06-28. PMID:6727365. |
autoradiography of the nasal region of rats injected with [4-14c]progesterone or [4-14c]testosterone showed a selective localization of radioactivity in the mucosa covering the olfactory region of the nasal cavity. |
1984-06-28 |
2023-08-12 |
rat |
| B Löfberg, H Tjälv. The disposition and metabolism of N-nitrosodiethylamine in adult, infant and foetal tissues of the Syrian golden hamster. Acta pharmacologica et toxicologica. vol 54. issue 2. 1984-05-24. PMID:6711317. |
experiments in vitro with tissues of adult hamsters showed a capacity of the nasal olfactory and respiratory mucosa, the trachea, the lung, the lateral nasal gland, the liver and the kidney to degrade the n-nitrosodiethylamine. |
1984-05-24 |
2023-08-12 |
Not clear |
| B Löfberg, H Tjälv. The disposition and metabolism of N-nitrosodiethylamine in adult, infant and foetal tissues of the Syrian golden hamster. Acta pharmacologica et toxicologica. vol 54. issue 2. 1984-05-24. PMID:6711317. |
the main targets for the n-nitrosodiethylamine carcinogenicity - the nasal olfactory and respiratory mucosa and the trachea - were found to be very active in degrading the substance, and it was shown that cytochrome p450 is present in these tissues. |
1984-05-24 |
2023-08-12 |
Not clear |
| B Löfberg, H Tjälv. The disposition and metabolism of N-nitrosodiethylamine in adult, infant and foetal tissues of the Syrian golden hamster. Acta pharmacologica et toxicologica. vol 54. issue 2. 1984-05-24. PMID:6711317. |
microautoradiography of the nasal mucosa showed the highest labelling over the subepithelial glands (bowman's glands) in the olfactory region, but other areas were also labelled. |
1984-05-24 |
2023-08-12 |
Not clear |
| M Casanova-Schmitz, R M David, H D Hec. Oxidation of formaldehyde and acetaldehyde by NAD+-dependent dehydrogenases in rat nasal mucosal homogenates. Biochemical pharmacology. vol 33. issue 7. 1984-05-23. PMID:6477684. |
homogenates of respiratory and olfactory tissue from the rat nasal cavity were examined for their capacity to catalyze the nad+-dependent oxidation of formaldehyde (in the presence and absence of glutathione) and of acetaldehyde. |
1984-05-23 |
2023-08-12 |
rat |
| C C Morse, M R Boyd, H Witsch. The effect of 3-methylfuran inhalation exposure on the rat nasal cavity. Toxicology. vol 30. issue 3. 1984-05-17. PMID:6710544. |
subsequent resolution of the acute olfactory necrosis was not complete and resulted in partial occlusive fibrosis of the nasal cavity as seen at 30 days. |
1984-05-17 |
2023-08-12 |
rat |
| B P Menc. Ciliated and microvillous structures of rat olfactory and nasal respiratory epithelia. A study using ultra-rapid cryo-fixation followed by freeze-substitution or freeze-etching. Cell and tissue research. vol 235. issue 2. 1984-05-02. PMID:6367994. |
ciliated and microvillous structures of rat olfactory and nasal respiratory epithelia. |
1984-05-02 |
2023-08-12 |
rat |
| R R Anholt, K M Murphy, G E Mack, S H Snyde. Peripheral-type benzodiazepine receptors in the central nervous system: localization to olfactory nerves. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 2. 1984-04-13. PMID:6321699. |
thus, [3h]ro5-4864 binding sites in the olfactory bulb appear in large part to be localized to olfactory nerves which originate in the nasal epithelium. |
1984-04-13 |
2023-08-12 |
Not clear |
| A Tamada, K Makimoto, M Okawa, Y Hirono, H Yamab. Olfactory neuroblastoma: presentation of a case and review of the Japanese literature. The Laryngoscope. vol 94. issue 2 Pt 1. 1984-03-16. PMID:6694503. |
olfactory neuroblastoma is an uncommon malignant tumor arising from the nasal cavity. |
1984-03-16 |
2023-08-12 |
Not clear |
| J F De Jonckheere, M Aerts, A J Martine. Naegleria australiensis: experimental meningoencephalitis in mice. Transactions of the Royal Society of Tropical Medicine and Hygiene. vol 77. issue 5. 1984-02-14. PMID:6659050. |
the involvement of the nasal mucosa, olfactory neuroepithelium and lobes, cerebrum and cerebellum was detected in haematoxylin-eosin stained paraffin-embedded sections. |
1984-02-14 |
2023-08-12 |
mouse |
| H Tjälve, B Löfber. Extrahepatic sites of metabolism of carbon tetrachloride in rats. Chemico-biological interactions. vol 46. issue 3. 1984-01-27. PMID:6416689. |
the structures identified to have a marked carbon tetrachloride-metabolizing capacity were, besides the liver, the mucosa of the bronchial tree, the tracheal mucosa, the olfactory and respiratory nasal mucosa, the oesophageal mucosa, the mucosa of the larynx, the tongue and the cheeks, the lateral nasal gland and the kidney cortex. |
1984-01-27 |
2023-08-12 |
rat |
| H Tjälve, B Löfber. Extrahepatic sites of metabolism of carbon tetrachloride in rats. Chemico-biological interactions. vol 46. issue 3. 1984-01-27. PMID:6416689. |
the nasal olfactory mucosa was found to be the tissue with the highest capacity to form 14co2 from the [14c]carbon tetrachloride and microautoradiography indicated that in this tissue the cells of the subepithelial glands of the lamina propria mucosae are most actively engaged in the metabolism. |
1984-01-27 |
2023-08-12 |
rat |
| H Tjälve, B Löfber. Extrahepatic sites of metabolism of carbon tetrachloride in rats. Chemico-biological interactions. vol 46. issue 3. 1984-01-27. PMID:6416689. |
it was also shown that cytochrome p-450 is present in the nasal olfactory mucosa. |
1984-01-27 |
2023-08-12 |
rat |
| B W Jafe. Ultrastructure of human nasal mucosa. The Laryngoscope. vol 93. issue 12. 1984-01-07. PMID:6645759. |
the intent of the study is to characterize the normal ultrastructure of human nasal mucosa with emphasis upon the difference between olfactory and respiratory epithelia. |
1984-01-07 |
2023-08-12 |
human |