| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hu-Ping Wang, Yun-Yun Hu, Yu-Jie Lyu, Zhi-Peng Meng, Yi-Qin Chen, Jiao Yan. [Effect of Hei Xiaoyaosan regulating p38MAPK/Beclin-1/Bcl-2 pathway on autophagy level in Alzheimer's disease model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 12. 2024-07-23. PMID:39041098. |
morris water maze was used to detect the learning and memory ability of rats, and hoechst staining was used to observe the pathological changes of nerve cells in the hippocampal ca1 region. |
2024-07-23 |
2024-07-25 |
rat |
| Alicia C Wells, Celina Mojica, Shahrdad Lotfipou. Hypersensitivity of the nicotinic acetylcholine receptor subunit (CHRNA2 Neurobiology of learning and memory. vol 213. 2024-07-05. PMID:38964600. |
chrna2 encodes for the α2 subunit of nicotinic acetylcholine receptors associated with ca1 oriens lacunosum moleculare gabaergic interneurons and is associated with learning and memory. |
2024-07-05 |
2024-07-08 |
Not clear |
| Amelia M Burch, Joshua D Garcia, Heather O'Leary, Ami Haas, James E Orfila, Erika Tiemeier, Nicholas Chalmers, Katharine R Smith, Nidia Quillinan, Paco S Herso. TRPM2 and CaMKII signaling drives excessive GABAergic synaptic inhibition following ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-04-02. PMID:38565288. |
we previously demonstrated sustained impairment of long-term potentiation (ltp) in hippocampal ca1 neurons correlating with deficits in learning and memory tasks in a murine model of cardiac arrest/ cardiopulmonary resuscitation (ca/cpr). |
2024-04-02 |
2024-04-05 |
Not clear |
| Hye-Ji Kim, Eun-A Ko, Oh-Bin Kwon, Sung-Cherl Jun. Prenatal treatment with corticosterone via maternal injection induces learning and memory impairments via delaying postsynaptic development in hippocampal CA1 neurons of rats. Journal of neuroscience research. vol 102. issue 4. 2024-03-30. PMID:38553948. |
prenatal treatment with corticosterone via maternal injection induces learning and memory impairments via delaying postsynaptic development in hippocampal ca1 neurons of rats. |
2024-03-30 |
2024-04-01 |
rat |
| Hye-Ji Kim, Eun-A Ko, Oh-Bin Kwon, Sung-Cherl Jun. Prenatal treatment with corticosterone via maternal injection induces learning and memory impairments via delaying postsynaptic development in hippocampal CA1 neurons of rats. Journal of neuroscience research. vol 102. issue 4. 2024-03-30. PMID:38553948. |
these results indicated that the prenatal treatment with corticosterone to elevate cortisol level might potently downregulate the bdnf-mediated signaling critical for the synaptic development of hippocampal ca1 neurons during brain development, and subsequently, induce learning and memory impairment. |
2024-03-30 |
2024-04-01 |
rat |
| Heng Kong, Yuan-Yuan Han, Gai-Ling Yang, Kang Li, Lu Yu, Xun-Kai Xie, Guang-Yuan Xia, Peng-Ju Wei, Wan-Rong Zhang, Chu-Hua L. Tenuifolin improves learning and memory by regulating long-term potentiation and dendritic structure of hippocampal CA1 area in healthy female mice but not male mice. Behavioural brain research. 2024-03-30. PMID:38554850. |
tenuifolin improves learning and memory by regulating long-term potentiation and dendritic structure of hippocampal ca1 area in healthy female mice but not male mice. |
2024-03-30 |
2024-04-02 |
mouse |
| Heng Kong, Yuan-Yuan Han, Gai-Ling Yang, Kang Li, Lu Yu, Xun-Kai Xie, Guang-Yuan Xia, Peng-Ju Wei, Wan-Rong Zhang, Chu-Hua L. Tenuifolin improves learning and memory by regulating long-term potentiation and dendritic structure of hippocampal CA1 area in healthy female mice but not male mice. Behavioural brain research. 2024-03-30. PMID:38554850. |
collectively, the results of the current study showed that ten improved learning and memory by regulating long-term potentiation (ltp) and dendritic structure of hippocampal ca1 area in female mice but not in males. |
2024-03-30 |
2024-04-02 |
mouse |
| Zhe Zhao, Hui Ji, Jiamin Pei, Jiaqing Yan, Xiangjian Zhang, Yi Yuan, Mengyang Li. Transcranial Ultrasound Stimulation Improves Memory Performance of Parkinsonian Mice. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 32. 2024-03-22. PMID:38498744. |
we found that ultrasound stimulation of the pd mice ca1 for 4 days: 1) significantly increased their learning and memory ability, although the learning and memory ability on the 7th day after the stimulation stopped was not significantly different from that before stimulation (p>0.05); 2) significantly increased the relative power of theta, low gamma, and high gamma frequency bands of the local field potential, and the phase amplitude coupling strength between theta and low gamma and between theta and high gamma; and 3) modulated the phase-locking angle between the spike of interneuron and theta wave to a 180°-360° rise cycle. |
2024-03-22 |
2024-03-24 |
mouse |
| Zhe Zhao, Hui Ji, Jiamin Pei, Jiaqing Yan, Xiangjian Zhang, Yi Yuan, Mengyang Li. Transcranial Ultrasound Stimulation Improves Memory Performance of Parkinsonian Mice. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 32. 2024-03-22. PMID:38498744. |
transcranial ultrasound stimulation can improve the learning and memory abilities of pd mice, and evoking neural oscillations in the ca1 is the potential mechanism. |
2024-03-22 |
2024-03-24 |
mouse |
| Qiao Ye, Gocylen Gast, Erik George Wilfley, Hanh Huynh, Chelsea Hays, Todd C Holmes, Xiangmin X. Monosynaptic rabies tracing reveals sex- and age-dependent dorsal subiculum connectivity alterations in an Alzheimer's disease mouse model. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-19. PMID:38503494. |
significant sex differences for sub inputs are found in 5xfad mice for ca1, ca2, ca3, postsub, prh, lec, and mec: all areas critical for learning and memory. |
2024-03-19 |
2024-03-23 |
mouse |
| Rebecca L Suthard, Ryan A Senne, Michelle D Buzharsky, Anh H Diep, Angela Y Pyo, Steve Ramire. Engram reactivation mimics cellular signatures of fear. Cell reports. vol 43. issue 3. 2024-02-24. PMID:38401120. |
to understand how artificial stimulation of fear affects intra-hippocampal neuron-astrocyte dynamics as well as their behavioral consequences, we express channelrhodopsin-2 in an activity-dependent manner within dentate gyrus neurons while recording both cell types with fiber photometry in hippocampal ventral ca1 across learning and memory. |
2024-02-24 |
2024-02-27 |
Not clear |
| Narjes Taherian, Gholamhassan Vaezi, Ali Neamati, Vida Hojjati, Faezeh Ghorbani-Taherdehi, Amirhossein Sahebkar, Mahmoud Gorji-Valokol. The dose-dependent neuroprotective effect of norepinephrine in improving memory retrieval in an experimental model of multiple sclerosis, experimental autoimmune encephalomyelitis. Brain research bulletin. 2024-02-23. PMID:38395110. |
the aim of this study was to assess the neuroprotective effects of nep on learning and memory disorders in an experimental animal model of ms. two guide cannulas were bilaterally implanted in the rat hippocampal ca1 regions. |
2024-02-23 |
2024-02-26 |
rat |
| Qionghua Hu, Lingqin Qiu, Li Ge, Yi We. Sevoflurane postconditioning alleviates hypoxic-ischemic brain damage in rats by inhibiting the endoplasmic reticulum stress PERK/ATF4/CHOP pathway. Tissue & cell. vol 86. 2024-01-09. PMID:38194851. |
following spc treatment, hibd rats exhibited improved spatial learning and memory abilities, reduced neuronal apoptosis, increased neuronal density in the hippocampal ca1 area, elevated bcl-2 protein level, decreased bax protein levels, and decreased levels of endoplasmic reticulum stress pathway related proteins (p-perk/perk, p-eif2/eif2, atf4, chop and grp78). |
2024-01-09 |
2024-01-13 |
rat |
| Glaucia Mara MenezesdaSilva, Eduardo Carvalho de Arruda Veiga, Manuel Jesus Simões, Ricardo Santos Simões, Marcos Eiji Shiroma, Maria Cândida Pinheiro Baracat, Givanna Santos Cavalcanti, Jose Maria Soares Junior, Edmund Chada Baraca. Effects of estrogen and raloxifene on synaptic density in the hippocampal CA1 region of ovariectomized rats. Clinics (Sao Paulo, Brazil). vol 78. 2023-11-28. PMID:38016196. |
the ca1 region of the hippocampus has an important role in learning and memory. |
2023-12-06 |
2023-12-07 |
rat |
| Glaucia Mara MenezesdaSilva, Eduardo Carvalho de Arruda Veiga, Manuel Jesus Simões, Ricardo Santos Simões, Marcos Eiji Shiroma, Maria Cândida Pinheiro Baracat, Givanna Santos Cavalcanti, Jose Maria Soares Junior, Edmund Chada Baraca. Effects of estrogen and raloxifene on synaptic density in the hippocampal CA1 region of ovariectomized rats. Clinics (Sao Paulo, Brazil). vol 78. 2023-11-28. PMID:38016196. |
the ca1 region of the hippocampus has an important role in learning and memory. |
2023-11-28 |
2023-12-07 |
rat |
| Xiao-Yan Zhang, Xie Wang, Ting Ye, Nan Shao, Jie Wang, Biao Cai, Dao-Jun Xi. Network pharmacology-based approach to understand the effect and mechanism of chrysophanol against cognitive impairment in Wilson disease. Metabolic brain disease. 2023-11-24. PMID:37999884. |
the rats fed with copper-laden diet for 12 weeks, and the effect of chr on the copper content in liver and 24-h urine, the learning and memory ability, the morphological changes and the apoptosis level of neurons in hippocampal ca1 region, the expression level of bax, bcl-2, cleaved caspase-3, p-pi3k, pi3k, p-akt, and akt proteins were detected. |
2023-11-24 |
2023-11-29 |
human |
| Yukitoshi Izumi, Kazuko A O'Dell, Charles F Zorumsk. The herbicide glyphosate inhibits hippocampal long-term potentiation and learning through activation of pro-inflammatory signaling. Scientific reports. vol 13. issue 1. 2023-10-21. PMID:37865669. |
in the ca1 region of rat hippocampal slices, we investigated whether glyphosate alters synaptic transmission and long-term potentiation (ltp), a cellular model of learning and memory. |
2023-10-21 |
2023-11-08 |
rat |
| Hongmei Wu, Dongyu Min, Buxun Sun, Yifan Ma, Hongpeng Chen, Jing Wu, Ping Ren, Jiabi Wu, Yonggang Cao, Baoshan Zhao, Peng Wan. Effect of WiFi signal exposure in utero and early life on neurodevelopment and behaviors of rats. Environmental science and pollution research international. 2023-08-10. PMID:37561300. |
the results showed that wifi signal exposure in utero and early life (1) increased the body weight of wifi + m (wifi + male) group; (2) no change in neuro-behavioral development was observed in wifi group; (3) increased learning and memory function in wifi + m group; (4) enhanced comparative levels of bdnf and p-creb proteins in the hippocampus of wifi + m group; (5) no neuronal loss or degeneration was detected, and neuronal numbers in hippocampal ca1 were no evidently differences in each group; (6) no change in the apoptosis-related proteins (caspase-3 and bax) levels; and (7) no difference in gsh-px and sod activities in the hippocampus. |
2023-08-10 |
2023-08-16 |
rat |
| Mo-Li Zhu, Jie Zhang, Li-Juan Guo, Rui-Zhu Yue, Shan-Shan Li, Bao-Yue Cui, Shuang Guo, Qian-Qian Niu, Ya-Nan Yu, Huan-Huan Wang, Lin Yang, Ya-Ling Yin, Shuang-Xi Wang, He-Qin Zhan, Zhi-Tao Gao, Peng L. Amorphous selenium inhibits oxidative stress injury of neurons in vascular dementia rats by activating NMDAR pathway. European journal of pharmacology. 2023-07-02. PMID:37394029. |
the results showed that a sends could significantly improve the learning and memory ability of vd rats, restore the posterior arterial blood flow of the brain, improve the neuronal morphology and dendritic remodeling of pyramidal cells in hippocampal ca1 area, reduce the level of oxidative stress in vd rats, increase the expression of nr2a, psd95, camk ii proteins and reduce intracellular calcium ion concentration, but the addition of selective nr2a antagonist nvp-aamo77 eliminated these benefits. |
2023-07-02 |
2023-08-14 |
rat |
| Xiao-Ling Zhong, Bo-Ying Tong, Yi-Han Yang, Hui-Ling Zeng, Chi Lin, Yuan Jing, Ling-Ling He, Shi-Jing Yo. [Effect of transcutaneous electrical acupoint stimulation on learning and memory ability of chronic fatigue syndrome rats and its mechanisms]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 4. 2023-05-15. PMID:37186194. |
to observe the effect of transcutaneous electrical acupoint stimulation (teas) on the histomorphological manifestations of hippocampal ca1 region and the expression of extracellular regulatory protein kinase (erk), cyclic adenosine response element binding protein (creb) and brain-derived neurotrophic factor (bdnf) in chronic fatigue syndrome (cfs) rats, so as to explore the mechanisms of teas in improving the learning and memory abilities of cfs rats. |
2023-05-15 |
2023-08-14 |
rat |