| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Zoratto, Amanda L Tringle, Giancarlo Bellenchi, Luisa Speranza, Domenica Travaglini, Umberto di Porzio, Carla Perrone-Capano, Giovanni Laviola, Jean-Luc Dreyer, Walter Adrian. Impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. Neuroscience letters. vol 548. 2014-02-07. PMID:23769733. |
impulsivity and home-cage activity are decreased by lentivirus-mediated silencing of serotonin transporter in the rat hippocampus. |
2014-02-07 |
2023-08-12 |
rat |
| Simon Trent, Rachel Dean, Bonnie Veit, Tommaso Cassano, Gaurav Bedse, Obah A Ojarikre, Trevor Humby, William Davie. Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology. vol 38. issue 8. 2014-01-31. PMID:23276394. |
subsequently, to specify potential behavioural correlates of elevated hippocampal 5-ht arising due to the genetic lesion, we compared 39,x(y*)o mf1 mice to 40,xy mf1 mice on behavioural tasks taxing hippocampal and/or 5-ht function (a 'foraging' task, an object-location task, and the 1-choice serial reaction time task of impulsivity). |
2014-01-31 |
2023-08-12 |
mouse |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
these data suggest that serotonin is selectively involved in pavlovian inhibition due to aversive expectations and have implications for our understanding of the mechanisms underlying a range of affective, impulsive, and aggressive neuropsychiatric disorders. |
2014-01-28 |
2023-08-12 |
Not clear |
| Sophie da Cunha-Bang, Dea Siggaard Stenbæk, Klaus Holst, Cecilie Löe Licht, Peter Steen Jensen, Vibe Gedsø Frokjaer, Erik Lykke Mortensen, Gitte Moos Knudse. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry research. vol 212. issue 2. 2013-11-19. PMID:23137806. |
numerous studies indicate that the serotonergic (5-ht) transmitter system is involved in the regulation of impulsive aggression and there is from post-mortem, in vivo imaging and genetic studies evidence that the 5-ht2a receptor may be involved. |
2013-11-19 |
2023-08-12 |
Not clear |
| Sophie da Cunha-Bang, Dea Siggaard Stenbæk, Klaus Holst, Cecilie Löe Licht, Peter Steen Jensen, Vibe Gedsø Frokjaer, Erik Lykke Mortensen, Gitte Moos Knudse. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry research. vol 212. issue 2. 2013-11-19. PMID:23137806. |
our findings are not supportive of a selective role for 5-ht2ar in mediating the 5-ht related effects on aggression and impulsivity in psychiatrically healthy individuals. |
2013-11-19 |
2023-08-12 |
Not clear |
| Bianca Jupp, Daniele Caprioli, Niel Saigal, Ingrid Reverte, Saurav Shrestha, Paul Cumming, Barry J Everitt, Trevor W Robbins, Jeffrey W Dalle. Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23368520. |
although decreased da d2/d3 receptor availability in the nucleus accumbens (nacb) predicts trait-like impulsivity in rats it is unclear whether this neurochemical marker extends to both the nacb core (nacbc) and shell (nacbs) and whether markers for other neurotransmitter systems implicated in impulsivity such as serotonin (5-ht), endogenous opioids and γ-amino-butyric acid (gaba) are likewise altered in impulsive rats. |
2013-10-28 |
2023-08-12 |
rat |
| Bianca Jupp, Daniele Caprioli, Niel Saigal, Ingrid Reverte, Saurav Shrestha, Paul Cumming, Barry J Everitt, Trevor W Robbins, Jeffrey W Dalle. Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23368520. |
we therefore used autoradiography to investigate da transporter (dat), 5-ht transporter (5-htt) and d1, d2/d3, μ-opioid and gaba(a) receptor binding in selected regions of the prefrontal cortex and striatum in rats expressing low and high impulsive behaviour on the five-choice serial reaction-time task. |
2013-10-28 |
2023-08-12 |
rat |
| b' Linn T Fikke, Annika Melinder, Nils I Landr\\xc3\\xb. The effects of acute tryptophan depletion on impulsivity and mood in adolescents engaging in non-suicidal self-injury. Human psychopharmacology. vol 28. issue 1. 2013-10-21. PMID:23359467.' |
low serotonin (5-hydroxytryptamine) function is associated with nssi, impaired emotion regulation and impulsivity. |
2013-10-21 |
2023-08-12 |
Not clear |
| b' Linn T Fikke, Annika Melinder, Nils I Landr\\xc3\\xb. The effects of acute tryptophan depletion on impulsivity and mood in adolescents engaging in non-suicidal self-injury. Human psychopharmacology. vol 28. issue 1. 2013-10-21. PMID:23359467.' |
we investigated the effects of experimentally lowered 5-hydroxytryptamine activity, via acute tryptophan depletion (atd), on impulsive action, reflection impulsivity and mood in female adolescents engaging in nssi. |
2013-10-21 |
2023-08-12 |
Not clear |
| Paul R Albert, Chawki Benkelfa. The neurobiology of depression--revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 368. issue 1615. 2013-09-12. PMID:23440469. |
indeed, it has become evident from therapeutic strategies that affect serotonin activity, that alterations in serotonin may not only predispose to depression, but also to aggressive behaviour, impulsivity, obsessive-compulsive behaviour and suicide. |
2013-09-12 |
2023-08-12 |
Not clear |
| J John Man. The serotonergic system in mood disorders and suicidal behaviour. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 368. issue 1615. 2013-09-12. PMID:23440471. |
the same neural circuitry and serotonin deficiency may contribute to impulsive aggressive traits that are part of the diathesis for suicidal behaviour and are associated with early onset mood disorders and greater risk for suicidal behaviour. |
2013-09-12 |
2023-08-12 |
Not clear |
| Paul J Fletcher, Ashlie D Soko, Guy A Higgin. Impulsive action in the 5-choice serial reaction time test in 5-HT₂c receptor null mutant mice. Psychopharmacology. vol 226. issue 3. 2013-08-29. PMID:23192316. |
depletion of brain serotonin (5-ht) results in impulsive behaviour as measured by increased premature responding in the five-choice serial reaction time (5-csrt) test. |
2013-08-29 |
2023-08-12 |
mouse |
| Jerzy Vetulan. [Neurochemistry of impulsiveness and aggression]. Psychiatria polska. vol 47. issue 1. 2013-08-22. PMID:23888748. |
aggression is modulated by several neurotransmitter and hormonal systems, of which the key role is seemingly played by testosterone, a hormone involved in domination behaviour, and serotonin, whose deficit results in increased impulsiveness. |
2013-08-22 |
2023-08-12 |
human |
| Enrica Audero, Boris Mlinar, Gilda Baccini, Zhiva K Skachokova, Renato Corradetti, Cornelius Gros. Suppression of serotonin neuron firing increases aggression in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678112. |
numerous studies link decreased serotonin metabolites with increased impulsive and aggressive traits. |
2013-08-02 |
2023-08-12 |
mouse |
| Menelaos L Batrino. Testosterone and aggressive behavior in man. International journal of endocrinology and metabolism. vol 10. issue 3. 2013-07-11. PMID:23843821. |
the degree of impulsivity is regulated by serotonin inhibiting receptors, and with the intervention of this neurotransmitter the major agents of the neuroendocrine influence on the brain process of aggression forms a triad. |
2013-07-11 |
2023-08-12 |
human |
| Kathryn A Cunningham, Noelle C Anastasio, Robert G Fox, Sonja J Stutz, Marcy J Bubar, Sarah E Swinford, Cheryl S Watson, Scott R Gilbertson, Kenner C Rice, Sharon Rosenzweig-Lipson, F Gerard Moelle. Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336050. |
these factors have been mechanistically linked to serotonin (5-hydroxytryptamine, 5-ht) signaling through the 5-ht(2a) receptor (5-ht(2a)r) and 5-ht(2c)r; either a selective 5-ht(2a)r antagonist or a 5-ht(2c)r agonist suppresses impulsivity and cocaine-seeking in preclinical models. |
2013-07-02 |
2023-08-12 |
Not clear |
| Kathryn A Cunningham, Noelle C Anastasio, Robert G Fox, Sonja J Stutz, Marcy J Bubar, Sarah E Swinford, Cheryl S Watson, Scott R Gilbertson, Kenner C Rice, Sharon Rosenzweig-Lipson, F Gerard Moelle. Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336050. |
combined administration of a dose of the selective 5-ht(2a)r antagonist m100907 plus the 5-ht(2c)r agonist way163909, each ineffective alone, synergistically suppressed cocaine-induced hyperactivity, inherent and cocaine-evoked impulsive action, as well as cue- and cocaine-primed reinstatement of cocaine-seeking behavior. |
2013-07-02 |
2023-08-12 |
Not clear |
| Alfredo Meneses, Gustavo Liy-Salmero. Serotonin and emotion, learning and memory. Reviews in the neurosciences. vol 23. issue 5-6. 2013-06-18. PMID:23104855. |
serotonin (5-hydroxytryptamien, 5-ht) has been linked to emotional and motivational aspects of human behavior, including anxiety, depression, impulsivity, etc. |
2013-06-18 |
2023-08-12 |
human |
| Iku Tsutsui-Kimura, Yu Ohmura, Takeshi Izumi, Haruko Kumamoto, Taku Yamaguchi, Takayuki Yoshida, Mitsuhiro Yoshiok. Milnacipran enhances the control of impulsive action by activating D₁-like receptors in the infralimbic cortex. Psychopharmacology. vol 225. issue 2. 2013-06-10. PMID:22892727. |
milnacipran increases not only extracellular serotonin and noradrenaline but also dopamine specifically in the medial prefrontal cortex, which is one of the brain regions responsible for impulsive action. |
2013-06-10 |
2023-08-12 |
rat |
| Angela J Rylands, Rainer Hinz, Matthew Jones, Sophie E Holmes, Maria Feldmann, Gavin Brown, Adam W McMahon, Peter S Talbo. Pre- and postsynaptic serotonergic differences in males with extreme levels of impulsive aggression without callous unemotional traits: a positron emission tomography study using (11)C-DASB and (11)C-MDL100907. Biological psychiatry. vol 72. issue 12. 2013-04-23. PMID:22835812. |
impulsive aggression (ia) in adults is associated with brain serotonin (5-ht) system abnormalities and is more common following childhood adversity. |
2013-04-23 |
2023-08-12 |
Not clear |