| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J K Zubieta, N E Aless. Is there a role of serotonin in the disruptive behavior disorders? A literature review. Journal of child and adolescent psychopharmacology. vol 3. issue 1. 2012-10-02. PMID:19630594. |
there is substantial evidence implicating 5ht systems in the modulation of motor activity, impulsive aggression, and learning and memory. |
2012-10-02 |
2023-08-12 |
human |
| David J Hellerstei. Review of the american psychiatric publishing textbook of personality disorders. Psychotherapy (Chicago, Ill.). vol 44. issue 1. 2012-10-02. PMID:22122175. |
with all its exciting insights into the impact of trauma, the interaction between genes, serotonin and impulsive behavior, and so forth, and with its occasional frustrations, the textbook of personality disorders provides an accurate, in-depth depiction of a true frontier of psychiatry. |
2012-10-02 |
2023-08-12 |
Not clear |
| Royce J Lee, Andrew Gill, Bing Chen, Michael McCloskey, Emil F Coccar. Modulation of central serotonin affects emotional information processing in impulsive aggressive personality disorder. Journal of clinical psychopharmacology. vol 32. issue 3. 2012-09-19. PMID:22544009. |
modulation of central serotonin affects emotional information processing in impulsive aggressive personality disorder. |
2012-09-19 |
2023-08-12 |
Not clear |
| Royce J Lee, Andrew Gill, Bing Chen, Michael McCloskey, Emil F Coccar. Modulation of central serotonin affects emotional information processing in impulsive aggressive personality disorder. Journal of clinical psychopharmacology. vol 32. issue 3. 2012-09-19. PMID:22544009. |
the mechanistic model whereby serotonin affects impulsive aggression is not completely understood. |
2012-09-19 |
2023-08-12 |
Not clear |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Catherine E Sykes, Mrudang M Shah, Dina M Francescutti, David R Rosenberg, David M Thomas, Donald M Kuh. Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity. Journal of neurochemistry. vol 121. issue 6. 2012-08-14. PMID:22443164. |
genetic depletion of brain 5ht reveals a common molecular pathway mediating compulsivity and impulsivity. |
2012-08-14 |
2023-08-12 |
mouse |
| Mariana Angoa-Pérez, Michael J Kane, Denise I Briggs, Catherine E Sykes, Mrudang M Shah, Dina M Francescutti, David R Rosenberg, David M Thomas, Donald M Kuh. Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity. Journal of neurochemistry. vol 121. issue 6. 2012-08-14. PMID:22443164. |
mice lacking tph2 (and brain 5ht) show intense compulsive and impulsive behaviors to include extreme aggression. |
2012-08-14 |
2023-08-12 |
mouse |
| Guy A Higgins, Leo B Silenieks, Anne Rossmann, Zoe Rizos, Kevin Noble, Ashlie D Soko, Paul J Fletche. The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 5. 2012-07-20. PMID:22189292. |
importantly, these results indicate that lorcaserin, and likely other selective 5-ht(2c) receptor agonists, similarly affect both food- and nicotine-motivated behaviors, and nicotine-induced impulsivity. |
2012-07-20 |
2023-08-12 |
rat |
| Yasumasa Okamoto, Go Okada, Kazuhiro Shishida, Takuji Fukumoto, Akihiko Machino, Hidehisa Yamashita, Saori C Tanaka, Kenji Doya, Shigeto Yamawak. [Effects of serotonin on delay discounting for rewards--an application for understanding of pathophysiology in psychiatric disorders]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 114. issue 2. 2012-07-19. PMID:22568113. |
our proposed role of serotonin may explain certain aspects of impulsivity in psychiatric disorders such as major depression, panic disorder or obsessive-compulsive disorder, that are known to effectively relieve symptoms by selective serotonin reuptake inhibitors. |
2012-07-19 |
2023-08-12 |
human |
| Simon Vermeire, Kurt Audenaert, Rudy De Meester, Eva Vandermeulen, Tim Waelbers, Bart De Spiegeleer, Jos Eersels, André Dobbeleir, Kathelijne Pereman. Neuro-imaging the serotonin 2A receptor as a valid biomarker for canine behavioural disorders. Research in veterinary science. vol 91. issue 3. 2012-07-10. PMID:21051063. |
the serotonergic system is disturbed in different mood and affective disorders, with especially the serotonin (5-ht) 2a receptor involved in impulsive aggressiveness and anxiety. |
2012-07-10 |
2023-08-12 |
dog |
| Simon Vermeire, Kurt Audenaert, Rudy De Meester, Eva Vandermeulen, Tim Waelbers, Bart De Spiegeleer, Jos Eersels, André Dobbeleir, Kathelijne Pereman. Neuro-imaging the serotonin 2A receptor as a valid biomarker for canine behavioural disorders. Research in veterinary science. vol 91. issue 3. 2012-07-10. PMID:21051063. |
significantly (p<0.0056) altered 5-ht 2a receptor binding indices were found in bilateral frontal, temporal and occipital cortical brain areas of the dogs behaving abnormally, with consistently increased bi in impulsive aggressive dogs and decreased bi in anxious dogs. |
2012-07-10 |
2023-08-12 |
dog |
| Simon Vermeire, Kurt Audenaert, Rudy De Meester, Eva Vandermeulen, Tim Waelbers, Bart De Spiegeleer, Jos Eersels, André Dobbeleir, Kathelijne Pereman. Neuro-imaging the serotonin 2A receptor as a valid biomarker for canine behavioural disorders. Research in veterinary science. vol 91. issue 3. 2012-07-10. PMID:21051063. |
we conclude that spect imaging with the radioligand (123)i-r91150 can be a helpful tool in evaluating the involvement of the serotonin 2a receptor in the complex mechanisms of impulsive aggressive and anxious behaviour. |
2012-07-10 |
2023-08-12 |
dog |
| Anne Matthys, Kathleen Van Craenenbroeck, Béatrice Lintermans, Guy Haegeman, Peter Vanhoenacke. RhoBTB3 interacts with the 5-HT7a receptor and inhibits its proteasomal degradation. Cellular signalling. vol 24. issue 5. 2012-06-06. PMID:22245496. |
the 5-hydroxytryptamine (5-ht)7 receptor is the most recently identified serotonin receptor and is involved in a wide variety of central nervous system (cns) functions, namely circadian rhythm, rem sleep, depression, thermoregulation, obsessive-compulsive disorder (ocd), anxiety, schizophrenia, epilepsy, nociception, migraine, sensation-seeking behavior, impulsivity, learning and memory. |
2012-06-06 |
2023-08-12 |
Not clear |
| Yoshihiko Demoto, Go Okada, Yasumasa Okamoto, Yoshihiko Kunisato, Shiori Aoyama, Keiichi Onoda, Ayumi Munakata, Michio Nomura, Saori C Tanaka, Nicolas Schweighofer, Kenji Doya, Shigeto Yamawak. Neural and personality correlates of individual differences related to the effects of acute tryptophan depletion on future reward evaluation. Neuropsychobiology. vol 65. issue 2. 2012-06-04. PMID:22222380. |
although deficits in the serotonergic system are implicated in this reward-delay impulsivity, there is individual variation in response to serotonin depletion. |
2012-06-04 |
2023-08-12 |
Not clear |
| K Luan Phan, Royce Lee, Emil F Coccar. Personality predictors of antiaggressive response to fluoxetine: inverse association with neuroticism and harm avoidance. International clinical psychopharmacology. vol 26. issue 5. 2012-05-29. PMID:21795983. |
although selective serotonin reuptake inhibitors (ssri) are generally effective in reducing impulsive aggression in individuals with intermittent explosive disorder, a large proportion of intermittent explosive disorder patients fail to achieve full remission despite adequate dosage and duration of treatment. |
2012-05-29 |
2023-08-12 |
human |
| Robert Marseille, Royce Lee, Emil F Coccar. Inter-relationship between different platelet measures of 5-HT and their relationship to aggression in human subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 36. issue 2. 2012-05-08. PMID:22019855. |
the objective of this study was to explore the inter-relationship of three platelet measures of serotonergic function (5-ht): 5-ht transporter binding, 5-ht-2 receptor binding and 5-ht content and to explore their inter-relationship with measures of aggression and impulsivity. |
2012-05-08 |
2023-08-12 |
human |
| Nathasha Moallem, Lara A Ra. Quetiapine improves response inhibition in alcohol dependent patients: a placebo-controlled pilot study. Pharmacology, biochemistry, and behavior. vol 100. issue 3. 2012-05-04. PMID:22037407. |
as an atypical antipsychotic medication with antagonist activity at d1 and d2, 5-ht(1a) and 5-ht(2a), h(1) and α1 and α2 receptors, quetiapine has been found to decrease impulsivity in other psychiatric disorders but its effects on impulsivity have not been studied in alcohol dependent patients. |
2012-05-04 |
2023-08-12 |
Not clear |
| Lena Wischhof, Michael Koc. Pre-treatment with the mGlu2/3 receptor agonist LY379268 attenuates DOI-induced impulsive responding and regional c-Fos protein expression. Psychopharmacology. vol 219. issue 2. 2012-05-01. PMID:21863235. |
overactivation of serotonin (5-hydroxytryptamine, 5-ht)(2a) receptors causes impulsivity and attentional deficits. |
2012-05-01 |
2023-08-12 |
Not clear |
| M J Crockett, L Clark, L D Smillie, T W Robbin. The effects of acute tryptophan depletion on costly information sampling: impulsivity or aversive processing? Psychopharmacology. vol 219. issue 2. 2012-05-01. PMID:22094531. |
the neurotransmitter serotonin (5-ht) has been implicated in both aversive processing and impulsivity. |
2012-05-01 |
2023-08-12 |
Not clear |
| Petra J J Baarendse, Louk J M J Vanderschure. Dissociable effects of monoamine reuptake inhibitors on distinct forms of impulsive behavior in rats. Psychopharmacology. vol 219. issue 2. 2012-05-01. PMID:22134476. |
the effectiveness of drugs targeting dopamine (da), noradrenaline (na) and/or serotonin (5-ht) in the treatment of impulse control disorders emphasizes the role of monoaminergic neurotransmission in impulsivity. |
2012-05-01 |
2023-08-12 |
rat |
| Judith R Homber. Serotonin and decision making processes. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:21693132. |
5-ht(2a) agonists and 5-ht2c antagonists decrease compulsivity, whereas 5-ht(2a) antagonists and 5-ht(2c) agonists decrease impulsivity. |
2012-04-19 |
2023-08-12 |
Not clear |