| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sofi da Cunha-Bang, Brenda Mc Mahon, Patrick MacDonald Fisher, Peter Steen Jensen, Claus Svarer, Gitte Moos Knudse. High trait aggression in men is associated with low 5-HT levels, as indexed by 5-HT4 receptor binding. Social cognitive and affective neuroscience. vol 11. issue 4. 2016-12-13. PMID:26772668. |
as cerebral 5-ht4 receptor (5-ht4r) binding has recently been recognized as a proxy for stable brain levels of 5-ht, we here test the hypothesis in healthy men and women that brain 5-ht levels, as indexed by cerebral 5-ht4r, are inversely correlated with trait aggression and impulsivity. |
2016-12-13 |
2023-08-13 |
human |
| Daan van Rooij, Catharina A Hartman, Marjolein M J van Donkelaar, Janita Bralten, Daniel von Rhein, Marina Hakobjan, Barbara Franke, Dirk J Heslenfeld, Jaap Oosterlaan, Nanda Rommelse, Jan K Buitelaar, Pieter J Hoekstr. Variation in serotonin neurotransmission genes affects neural activation during response inhibition in adolescents and young adults with ADHD and healthy controls. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 16. issue 8. 2016-09-21. PMID:26428549. |
given the role of serotonin in adhd and impulsivity, we postulated that genetic variants within the serotonin pathway might influence response inhibition. |
2016-09-21 |
2023-08-13 |
Not clear |
| Amy R Glic. The role of serotonin in impulsive aggression, suicide, and homicide in adolescents and adults: a literature review. International journal of adolescent medicine and health. vol 27. issue 2. 2016-08-29. PMID:25924230. |
the role of serotonin in impulsive aggression, suicide, and homicide in adolescents and adults: a literature review. |
2016-08-29 |
2023-08-13 |
Not clear |
| Amy R Glic. The role of serotonin in impulsive aggression, suicide, and homicide in adolescents and adults: a literature review. International journal of adolescent medicine and health. vol 27. issue 2. 2016-08-29. PMID:25924230. |
the review demonstrates that there is a clear association between low cerebrospinal fluid serotonin and impulsive aggression. |
2016-08-29 |
2023-08-13 |
Not clear |
| Amy R Glic. The role of serotonin in impulsive aggression, suicide, and homicide in adolescents and adults: a literature review. International journal of adolescent medicine and health. vol 27. issue 2. 2016-08-29. PMID:25924230. |
serotonin supplementation studies suggest that selective serotonin reuptake inhibitors may reduce impulsive aggression in some adults but are less effective in adults with pathological aggression and also in children and adolescents. |
2016-08-29 |
2023-08-13 |
Not clear |
| Pothitos M Pitychoutis, Arnauld Belmer, Imane Moutkine, Joëlle Adrien, Luc Maroteau. Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 12. 2016-08-02. PMID:25936642. |
recently, a population-specific serotonin 2b (5-ht2b) receptor stop codon (ie, htr2b q20*) was reported to segregate with severely impulsive individuals, whereas 5-ht2b mutant (htr2b(-/-)) mice also showed high impulsivity. |
2016-08-02 |
2023-08-13 |
mouse |
| R Tikkanen, J Tiihonen, M R Rautiainen, T Paunio, L Bevilacqua, R Panarsky, D Goldman, M Virkkune. Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon. Translational psychiatry. vol 5. 2016-07-19. PMID:26575222. |
impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2b receptor stop codon. |
2016-07-19 |
2023-08-13 |
Not clear |
| R Tikkanen, J Tiihonen, M R Rautiainen, T Paunio, L Bevilacqua, R Panarsky, D Goldman, M Virkkune. Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon. Translational psychiatry. vol 5. 2016-07-19. PMID:26575222. |
a relatively common stop codon (q20*) was identified in the serotonin 2b receptor gene (htr2b) in a finnish founder population in 2010 and it was associated with impulsivity. |
2016-07-19 |
2023-08-13 |
Not clear |
| Qi Ye, Jonghan Ki. Effect of olfactory manganese exposure on anxiety-related behavior in a mouse model of iron overload hemochromatosis. Environmental toxicology and pharmacology. vol 40. issue 1. 2016-06-07. PMID:26189056. |
moreover, hfe deficiency attenuated manganese-associated impulsivity and modified the effect of manganese on the expression of tyrosine hydroxylase, vesicular monoamine transporter and serotonin transporter. |
2016-06-07 |
2023-08-13 |
mouse |
| Mahesh Darna, Jonathan J Chow, Justin R Yates, Richard J Charnigo, Joshua S Beckmann, Michael T Bardo, Linda P Dwoski. Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice. Behavioural brain research. vol 293. 2016-06-02. PMID:26183652. |
dysregulation of 5-hydroxytryptamine (serotonin, 5-ht) systems in subregions of the prefrontal cortex has been implicated in impulsivity. |
2016-06-02 |
2023-08-13 |
rat |
| Mahesh Darna, Jonathan J Chow, Justin R Yates, Richard J Charnigo, Joshua S Beckmann, Michael T Bardo, Linda P Dwoski. Role of serotonin transporter function in rat orbitofrontal cortex in impulsive choice. Behavioural brain research. vol 293. 2016-06-02. PMID:26183652. |
extracellular 5-ht concentrations are regulated by 5-ht transporters (serts), indicating that these transporters may be important molecular targets underlying individual differences in impulsivity and drug abuse vulnerability. |
2016-06-02 |
2023-08-13 |
rat |
| Shijing Liu, Lorena Maili, Scott D Lane, Joy M Schmitz, Catherine J Spellicy, Kathryn A Cunningham, F Gerard Moeller, David A Nielse. Serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity. Psychiatric genetics. vol 25. issue 5. 2016-05-19. PMID:26110342. |
serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity. |
2016-05-19 |
2023-08-13 |
Not clear |
| Noelle C Anastasio, Sonja J Stutz, Latham H L Fink, Sarah E Swinford-Jackson, Robert M Sears, Ralph J DiLeone, Kenner C Rice, F Gerard Moeller, Kathryn A Cunningha. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26120876. |
serotonin (5-ht) 5-ht2a receptor (5-ht2ar):5-ht2cr imbalance in medial prefrontal cortex associates with motor impulsivity. |
2016-04-19 |
2023-08-13 |
rat |
| Noelle C Anastasio, Sonja J Stutz, Latham H L Fink, Sarah E Swinford-Jackson, Robert M Sears, Ralph J DiLeone, Kenner C Rice, F Gerard Moeller, Kathryn A Cunningha. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26120876. |
recent studies have implicated serotonin (5-ht) systems in medial prefrontal cortex (mpfc) in mediating individual differences in motor impulsivity, notably the 5-ht2ar receptor (5-ht2ar) and 5-ht2cr. |
2016-04-19 |
2023-08-13 |
rat |
| C L Bethea, K Phu, A Kim, A P Redd. Androgen metabolites impact CSF amines and axonal serotonin via MAO-A and -B in male macaques. Neuroscience. vol 301. 2016-04-18. PMID:26086546. |
a number of studies have shown that mutations or deletions of the monoamine oxidase-a (mao-a) gene cause elevated cns serotonin and elevated impulsive aggression in humans and animal models. |
2016-04-18 |
2023-08-13 |
monkey |
| Molly J Crockett, Jenifer Z Siegel, Zeb Kurth-Nelson, Olga T Ousdal, Giles Story, Carolyn Frieband, Johanna M Grosse-Rueskamp, Peter Dayan, Raymond J Dola. Dissociable Effects of Serotonin and Dopamine on the Valuation of Harm in Moral Decision Making. Current biology : CB. vol 25. issue 14. 2016-04-18. PMID:26144968. |
crucially, neither drug influenced the physical perception of pain or other components of choice such as motor impulsivity or loss aversion, suggesting a direct and specific influence of serotonin and dopamine on the valuation of harm. |
2016-04-18 |
2023-08-13 |
human |
| Adrian G Fischer, Tanja Endrass, Ingrid Goebel, Martin Reuter, Christian Montag, Christian Kubisch, Markus Ullsperge. Interactive effects of citalopram and serotonin transporter genotype on neural correlates of response inhibition and attentional orienting. NeuroImage. vol 116. 2016-04-08. PMID:25957993. |
the brain's serotonergic (5-ht) system has been implicated in controlling impulsive behavior and attentional orienting and linked to impulse control and anxiety related disorders. |
2016-04-08 |
2023-08-13 |
human |
| Justin R Yates, Mahesh Darna, Cassandra D Gipson, Linda P Dwoskin, Michael T Bard. Dissociable roles of dopamine and serotonin transporter function in a rat model of negative urgency. Behavioural brain research. vol 291. 2016-03-28. PMID:26005123. |
several brain regions within the mesocorticolimbic pathway, as well as the neurotransmitters dopamine (da) and serotonin (5-ht), have been implicated in impulsivity. |
2016-03-28 |
2023-08-13 |
rat |
| M Hansenne, W Pitchot, M Anssea. Serotonin, personality and borderline personality disorder. Acta neuropsychiatrica. vol 14. issue 2. 2016-03-18. PMID:26983967. |
indeed, several reports have demonstrated the efficacy of selective serotonin re-uptake drugs in treating the depressive and impulsive symptoms of patients with bpd. |
2016-03-18 |
2023-08-13 |
Not clear |
| W M Verhoeven, S Tuinie. Biological and psychopharmacological aspects of impulse-control disorders. Acta neuropsychiatrica. vol 9. issue 2. 2016-03-14. PMID:26972136. |
concerning aggression and other types of disruptive or impulsive behavior, research on their neurobiological determinants has been focussed mainly on indicators of central 5-ht function. |
2016-03-14 |
2023-08-13 |
Not clear |