| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Carli, R Samani. The 5-HT(1A) receptor agonist 8-OH-DPAT reduces rats' accuracy of attentional performance and enhances impulsive responding in a five-choice serial reaction time task: role of presynaptic 5-HT(1A) receptors. Psychopharmacology. vol 149. issue 3. 2000-08-29. PMID:10823407. |
the 5-ht(1a) receptor agonist 8-oh-dpat reduces rats' accuracy of attentional performance and enhances impulsive responding in a five-choice serial reaction time task: role of presynaptic 5-ht(1a) receptors. |
2000-08-29 |
2023-08-12 |
rat |
| U D McCann, V Eligulashvili, G A Ricaurt. (+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: clinical studies. Neuropsychobiology. vol 42. issue 1. 2000-08-29. PMID:10867551. |
functional abnormalities seen in mdma users that may be related to 5- ht injury include cognitive deficits, altered sleep architecture, altered neuroendocrine function, altered behavioral responses to 5-ht selective drugs, and increased impulsivity. |
2000-08-29 |
2023-08-12 |
human |
| F Askenazy, H Caci, M Myquel, G Darcourt, Y Lecrubie. Relationship between impulsivity and platelet serotonin content in adolescents. Psychiatry research. vol 94. issue 1. 2000-08-07. PMID:10788674. |
relationship between impulsivity and platelet serotonin content in adolescents. |
2000-08-07 |
2023-08-12 |
human |
| F Askenazy, H Caci, M Myquel, G Darcourt, Y Lecrubie. Relationship between impulsivity and platelet serotonin content in adolescents. Psychiatry research. vol 94. issue 1. 2000-08-07. PMID:10788674. |
the relationship between impulsivity and serotonin function was explored in impulsive and non-depressed adolescents. |
2000-08-07 |
2023-08-12 |
human |
| F Askenazy, H Caci, M Myquel, G Darcourt, Y Lecrubie. Relationship between impulsivity and platelet serotonin content in adolescents. Psychiatry research. vol 94. issue 1. 2000-08-07. PMID:10788674. |
mean platelet serotonin concentration was significantly higher in the impulsive group than in the control group. |
2000-08-07 |
2023-08-12 |
human |
| F Askenazy, H Caci, M Myquel, G Darcourt, Y Lecrubie. Relationship between impulsivity and platelet serotonin content in adolescents. Psychiatry research. vol 94. issue 1. 2000-08-07. PMID:10788674. |
platelet serotonin concentration was positively correlated with the intensity of impulsivity in the patient group. |
2000-08-07 |
2023-08-12 |
human |
| E Balaban, J S Alper, Y L Kasamo. Mean genes and the biology of aggression: a critical review of recent animal and human research. Journal of neurogenetics. vol 11. issue 1-2. 2000-07-21. PMID:10876648. |
recent genetic work has suggested that abnormalities in serotonin biochemistry are directly causally linked to aggressive behavior, and there appears to be a consensus in the psychiatric literature that low levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa) in cerebrospinal fluid are specifically associated with impulsive violent behavior. |
2000-07-21 |
2023-08-12 |
human |
| J Evans, H Platts, S Lightman, D Nut. Impulsiveness and the prolactin response to d-fenfluramine. Psychopharmacology. vol 149. issue 2. 2000-07-17. PMID:10805609. |
a number of studies have reported abnormalities of serotonin function in aggressive and impulsive behaviours in psychiatric and forensic populations. |
2000-07-17 |
2023-08-12 |
Not clear |
| J Evans, H Platts, S Lightman, D Nut. Impulsiveness and the prolactin response to d-fenfluramine. Psychopharmacology. vol 149. issue 2. 2000-07-17. PMID:10805609. |
it is unknown whether this is because serotonin function plays a part in determining the dimension of trait impulsiveness in the general population or whether this is restricted to these behaviourally extreme groups. |
2000-07-17 |
2023-08-12 |
Not clear |
| S N Young, M Leyton, C Benkelfa. Pet studies of serotonin synthesis in the human brain. Advances in experimental medicine and biology. vol 467. 2000-05-09. PMID:10721033. |
patients with borderline personality disorder, who exhibit emotional lability and impulsivity, may have lower brain serotonin synthesis rates than healthy controls. |
2000-05-09 |
2023-08-12 |
human |
| L Buydens-Branchey, M Branchey, J Hudson, P Fergeso. Low HDL cholesterol, aggression and altered central serotonergic activity. Psychiatry research. vol 93. issue 2. 2000-05-09. PMID:10725526. |
this study was designed to explore the relationship between plasma cholesterol, measures of impulsivity and aggression, and indices of 5-ht function in personality disordered cocaine addicts. |
2000-05-09 |
2023-08-12 |
Not clear |
| J L Carrasco, M Díaz-Marsá, E Hollander, J César, J Saiz-Rui. Decreased platelet monoamine oxidase activity in female bulimia nervosa. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 2. 2000-05-08. PMID:10706992. |
platelet mao activity is an index of brain serotonin activity and lowered platelet mao levels have been found in association with impulsive behaviors. |
2000-05-08 |
2023-08-12 |
Not clear |
| M A Oquendo, J J Man. The biology of impulsivity and suicidality. The Psychiatric clinics of North America. vol 23. issue 1. 2000-04-20. PMID:10729928. |
abnormalities of 5-ht and noradrenergic functioning have been implicated in aggressive impulsivity, sib, and suicidal behavior. |
2000-04-20 |
2023-08-12 |
human |
| M A Oquendo, J J Man. The biology of impulsivity and suicidality. The Psychiatric clinics of North America. vol 23. issue 1. 2000-04-20. PMID:10729928. |
most studies suggest that impulsive aggression is related to lower levels of cns 5-ht. |
2000-04-20 |
2023-08-12 |
human |
| M A Oquendo, J J Man. The biology of impulsivity and suicidality. The Psychiatric clinics of North America. vol 23. issue 1. 2000-04-20. PMID:10729928. |
suicidal behaviors and the lethality of suicide attempts may also be linked to the abnormalities in neurotransmitter systems similar to those found in patients with impulsive aggression and sib, namely, lowered 5-ht transmission and enhanced da and ne functioning. |
2000-04-20 |
2023-08-12 |
human |
| S M Southwick, S Paige, C A Morgan, J D Bremner, J H Krystal, D S Charne. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Seminars in clinical neuropsychiatry. vol 4. issue 4. 1999-12-13. PMID:10553029. |
evidence of serotonergic dysregulation in ptsd includes frequent symptoms of aggression, impulsivity, depression and suicidality, decreased platelet paroxetine binding, blunted prolactin response to fenfluramine, exaggerated reactivity to m-chloro-phenyl-piperazine, and clinical efficacy of serotonin reuptake inhibitors. |
1999-12-13 |
2023-08-12 |
Not clear |
| S M Southwick, S Paige, C A Morgan, J D Bremner, J H Krystal, D S Charne. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Seminars in clinical neuropsychiatry. vol 4. issue 4. 1999-12-13. PMID:10553029. |
it has been suggested that alterations in ne, e, and 5-ht may have relevance for symptoms commonly seen in survivors with ptsd, including hypervigilance, exaggerated startle, irritability, impulsivity, aggression, intrusive memories, depressed mood, and suicidality. |
1999-12-13 |
2023-08-12 |
Not clear |
| J Bizot, C Le Bihan, A J Puech, M Hamon, M Thiébo. Serotonin and tolerance to delay of reward in rats. Psychopharmacology. vol 146. issue 4. 1999-11-30. PMID:10550490. |
tolerance to delay of gratification, taken to reflect impulsiveness, has been proposed to be under the preferential control of central serotonin (5-ht) processes. |
1999-11-30 |
2023-08-12 |
rat |
| D R Cherek, S D Lan. Effects of d,l-fenfluramine on aggressive and impulsive responding in adult males with a history of conduct disorder. Psychopharmacology. vol 146. issue 4. 1999-11-30. PMID:10550498. |
the role of serotonin in aggression and impulsivity was examined by administering the serotonin-releasing drug, d, l-fenfluramine and measuring effects on aggressive and impulsive responding under controlled laboratory conditions. |
1999-11-30 |
2023-08-12 |
Not clear |
| A Rotondo, K Schuebel, A Bergen, R Aragon, M Virkkunen, M Linnoila, D Goldman, D Nielse. Identification of four variants in the tryptophan hydroxylase promoter and association to behavior. Molecular psychiatry. vol 4. issue 4. 1999-10-18. PMID:10483053. |
one of the most replicated findings in biological psychiatry is the observation of lower 5-hydroxyindoleacetic acid concentrations, the major metabolite of serotonin, in the brain and cerebrospinal fluid of subjects with impulsive aggression. |
1999-10-18 |
2023-08-12 |
human |