| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heddeke Snoek, Stephanie H M van Goozen, Walter Matthys, Hein O Sigling, Hans P F Koppeschaar, Herman G M Westenberg, Herman van Engelan. Serotonergic functioning in children with oppositional defiant disorder: a sumatriptan challenge study. Biological psychiatry. vol 51. issue 4. 2002-05-30. PMID:11958783. |
there is recent evidence from studies on 5-ht(1b) knock-out mice that this specific receptor is involved in impulsive aggressive behavior. |
2002-05-30 |
2023-08-12 |
mouse |
| Robert D Oade. Dopamine may be 'hyper' with respect to noradrenaline metabolism, but 'hypo' with respect to serotonin metabolism in children with attention-deficit hyperactivity disorder. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864724. |
serotonin: the relevance for adhd of an association of impulsivity with low serotonin (5-ht) metabolism (behav brain sci 1986;9:319) has long been played down. |
2002-05-16 |
2023-08-12 |
Not clear |
| Don R Cherek, Scott D Lane, Cynthia J Pietras, Joel L Steinber. Effects of chronic paroxetine administration on measures of aggressive and impulsive responses of adult males with a history of conduct disorder. Psychopharmacology. vol 159. issue 3. 2002-05-07. PMID:11862359. |
the role of serotonin in human aggression and impulsivity was evaluated by administering paroxetine or placebo for 3 weeks and comparing the effects on laboratory measures of aggression and impulsivity among male subjects with a history of conduct disorder. |
2002-05-07 |
2023-08-12 |
human |
| M Kamali, M A Oquendo, J J Man. Understanding the neurobiology of suicidal behavior. Depression and anxiety. vol 14. issue 3. 2002-04-18. PMID:11747126. |
this deficiency in turn can lead to a predisposition to impulsive and aggressive behavior, probably due to a breakdown in the inhibitory function of the ventral prefrontal cortex as a result of less serotonin input. |
2002-04-18 |
2023-08-12 |
Not clear |
| Tuija Mantere, Erkki Tupala, Håkan Hall, Terttu Särkioja, Pirkko Räsänen, Kim Bergström, James Callaway, Jari Tiihone. Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography study. The American journal of psychiatry. vol 159. issue 4. 2002-04-18. PMID:11925298. |
lesions of the medial prefrontal cortex and dysfunctions in serotonin turnover are two well-established factors associated with impulsive and sociopathic behaviors, but no firm neuroanatomical data have linked these pathophysiological findings. |
2002-04-18 |
2023-08-12 |
human |
| H Soderstrom, K Blennow, A Manhem, A Forsma. CSF studies in violent offenders. I. 5-HIAA as a negative and HVA as a positive predictor of psychopathy. Journal of neural transmission (Vienna, Austria : 1996). vol 108. issue 7. 2002-01-22. PMID:11515752. |
low serotonin activity in man has been related to impulsive, self-destructive violence but not to instrumental aggression aimed at dominance. |
2002-01-22 |
2023-08-12 |
Not clear |
| D R Cherek, S D Lan. Acute effects of D-fenfluramine on simultaneous measures of aggressive escape and impulsive responses of adult males with and without a history of conduct disorder. Psychopharmacology. vol 157. issue 3. 2001-12-20. PMID:11605076. |
the role of serotonin in human aggression was evaluated by administering d-fenfluramine and comparing the effects on laboratory measures of aggression, escape and impulsivity among subjects with and without a history of conduct disorder. |
2001-12-20 |
2023-08-12 |
human |
| J Tiihonen, M Virkkunen, P Räsänen, S Pennanen, E L Sainio, J Callaway, P Halonen, J Liesivuor. Free L-tryptophan plasma levels in antisocial violent offenders. Psychopharmacology. vol 157. issue 4. 2001-12-19. PMID:11605099. |
several studies have shown that impulsive violent behavior is associated with reduced serotonin metabolism in the brain, but no data exist on possible alterations of the serotonin precursor (free l-tryptophan) levels among violent offenders. |
2001-12-19 |
2023-08-12 |
Not clear |
| G Zalsman, A Frisch, M Bromberg, J Gelernter, E Michaelovsky, A Campino, Z Erlich, S Tyano, A Apter, A Weizma. Family-based association study of serotonin transporter promoter in suicidal adolescents: no association with suicidality but possible role in violence traits. American journal of medical genetics. vol 105. issue 3. 2001-12-04. PMID:11353442. |
suicide and suicide-related behaviors such as violence, aggression, and impulsivity have been reproducibly associated with serotonin dysfunction and are partially genetic. |
2001-12-04 |
2023-08-12 |
Not clear |
| I Manor, J Eisenberg, S Tyano, Y Sever, H Cohen, R P Ebstein, M Kotle. Family-based association study of the serotonin transporter promoter region polymorphism (5-HTTLPR) in attention deficit hyperactivity disorder. American journal of medical genetics. vol 105. issue 1. 2001-10-25. PMID:11425009. |
low serotonin activity has been associated in both animal and human studies with measures of impulsivity, aggression, and disinhibited behaviors. |
2001-10-25 |
2023-08-12 |
human |
| A S New, J Gelernter, M Goodman, V Mitropoulou, H Koenigsberg, J Silverman, L J Sieve. Suicide, impulsive aggression, and HTR1B genotype. Biological psychiatry. vol 50. issue 1. 2001-10-25. PMID:11457425. |
suicidality and impulsive aggression are partially heritable, and postmortem brain studies suggest that abnormalities in serotonin 1b may be associated with suicide. |
2001-10-25 |
2023-08-12 |
mouse |
| M Goodman, A Ne. Impulsive aggression in borderline personality disorder. Current psychiatry reports. vol 2. issue 1. 2001-08-09. PMID:11122933. |
the underlying biologic basis for impulsive aggression is centered on the serotonin hypothesis; that central 5-ht function is inversely related to aggression and suicidality. |
2001-08-09 |
2023-08-12 |
Not clear |
| O Spreux-Varoquaux, J C Alvarez, I Berlin, G Batista, P G Despierre, A Gilton, D Cremnite. Differential abnormalities in plasma 5-HIAA and platelet serotonin concentrations in violent suicide attempters: relationships with impulsivity and depression. Life sciences. vol 69. issue 6. 2001-08-09. PMID:11476186. |
differential abnormalities in plasma 5-hiaa and platelet serotonin concentrations in violent suicide attempters: relationships with impulsivity and depression. |
2001-08-09 |
2023-08-12 |
Not clear |
| O Spreux-Varoquaux, J C Alvarez, I Berlin, G Batista, P G Despierre, A Gilton, D Cremnite. Differential abnormalities in plasma 5-HIAA and platelet serotonin concentrations in violent suicide attempters: relationships with impulsivity and depression. Life sciences. vol 69. issue 6. 2001-08-09. PMID:11476186. |
plasma 5-hiaa concentration was inversely associated with the degree of impulsivity and platelet 5-ht with the intensity of depression. |
2001-08-09 |
2023-08-12 |
Not clear |
| C Reist, C Mazzanti, R Vu, D Tran, D Goldma. Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine. American journal of medical genetics. vol 105. issue 4. 2001-07-19. PMID:11378851. |
disturbances in central serotonin (5-ht) function may have a role in impulsive aggression in patients with a wide range of psychiatric diagnoses. |
2001-07-19 |
2023-08-12 |
human |
| C Reist, C Mazzanti, R Vu, D Tran, D Goldma. Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine. American journal of medical genetics. vol 105. issue 4. 2001-07-19. PMID:11378851. |
in the present study, we examined the relationship between polymorphisms in the promoter region of the gene coding for the neuronal 5-ht transporter, fenfluramine-induced prolactin release, and aggressive impulsivity (as measured by barratt impulsivity scale, buss-durkee hostility inventory, and brown-goodwin aggression scale scores), in a group of abstinent alcoholic patients and healthy volunteers. |
2001-07-19 |
2023-08-12 |
human |
| C Reist, C Mazzanti, R Vu, D Tran, D Goldma. Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine. American journal of medical genetics. vol 105. issue 4. 2001-07-19. PMID:11378851. |
we found no relationship between aggressive, hostile, or impulsive traits and fenfluramine-induced prolactin release or between these traits and polymorphisms in the 5-ht transporter promoter. |
2001-07-19 |
2023-08-12 |
human |
| P H Soloff, K G Lynch, H B Mos. Serotonin, impulsivity, and alcohol use disorders in the older adolescent: a psychobiological study. Alcoholism, clinical and experimental research. vol 24. issue 11. 2001-05-31. PMID:11104107. |
serotonin, impulsivity, and alcohol use disorders in the older adolescent: a psychobiological study. |
2001-05-31 |
2023-08-12 |
Not clear |
| M Dolan, I M Anderson, J F Deaki. Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. The British journal of psychiatry : the journal of mental science. vol 178. 2001-05-31. PMID:11282815. |
relationship between 5-ht function and impulsivity and aggression in male offenders with personality disorders. |
2001-05-31 |
2023-08-12 |
Not clear |
| L A Fairbanks, W P Melega, M J Jorgensen, J R Kaplan, M T McGuir. Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 4. 2001-05-24. PMID:11182532. |
in the first study, an index of impulsivity in response to an unfamiliar adult male intruder (including latency to approach and aggressive and assertive interactions) was inversely correlated with levels of the serotonin metabolite, 5-hydroxyindoleacetic acid (5-hiaa) in cisternal cerebrospinal fluid (r = -0.33, p <.01, n = 138). |
2001-05-24 |
2023-08-12 |
human |