| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Leyton, H Okazawa, M Diksic, J Paris, P Rosa, S Mzengeza, S N Young, P Blier, C Benkelfa. Brain Regional alpha-[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. The American journal of psychiatry. vol 158. issue 5. 2001-05-24. PMID:11329401. |
neurotransmission of serotonin (or 5-hydroxytryptamine [5-ht]) is thought to be disturbed in patients exhibiting impulsive behaviors. |
2001-05-24 |
2023-08-12 |
human |
| A I Svensson, A Berntsson, J A Engel, B Söderpal. Disinhibitory behavior and GABA(A) receptor function in serotonin-depleted adult male rats are reduced by gonadectomy. Pharmacology, biochemistry, and behavior. vol 67. issue 3. 2001-04-19. PMID:11164093. |
impulsive and aggressive behaviors in, e.g., personality or substance abuse disorders in man and corresponding behaviors in rats may involve serotonin (5-ht), gamma-amino-butyric acid(a)/benzodiazepine receptor complexes (gaba(a)/bdz-rc) and steroid hormones, e.g., testosterone. |
2001-04-19 |
2023-08-12 |
rat |
| R Lee, E Coccar. The neuropsychopharmacology of criminality and aggression. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 46. issue 1. 2001-04-19. PMID:11221488. |
serotonin is not the only aspect of brain function implicated in impulsive aggression, and further work is being done on other neurotransmitters and neuropeptides. |
2001-04-19 |
2023-08-12 |
Not clear |
| S Chiavegatto, V L Dawson, L A Mamounas, V E Koliatsos, T M Dawson, R J Nelso. Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 3. 2001-04-12. PMID:11158630. |
we now demonstrate that the excessive aggressiveness and impulsiveness of nnos knockout mice is caused by selective decrements in serotonin (5-ht) turnover and deficient 5-ht(1a) and 5-ht(1b) receptor function in brain regions regulating emotion. |
2001-04-12 |
2023-08-12 |
mouse |
| S Chiavegatto, V L Dawson, L A Mamounas, V E Koliatsos, T M Dawson, R J Nelso. Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 3. 2001-04-12. PMID:11158630. |
these results indicate an important role for no in normal brain 5-ht function and may have significant implications for the treatment of psychiatric disorders characterized by aggressiveness and impulsivity. |
2001-04-12 |
2023-08-12 |
mouse |
| K A Nolan, J Volavka, H M Lachman, T Sait. An association between a polymorphism of the tryptophan hydroxylase gene and aggression in schizophrenia and schizoaffective disorder. Psychiatric genetics. vol 10. issue 3. 2001-04-12. PMID:11204346. |
polymorphisms in the regulatory region of the serotonin transporter (5-htt), in intron 7 of the tryptophan hydroxylase (tph) gene and in the maoa gene were previously reported to be associated with mood and anxiety disorders, impulsivity and aggression. |
2001-04-12 |
2023-08-12 |
Not clear |
| H Steiger, S N Young, N M Kin, N Koerner, M Israel, P Lageix, J Pari. Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa. Psychological medicine. vol 31. issue 1. 2001-03-29. PMID:11200963. |
implications of impulsive and affective symptoms for serotonin function in bulimia nervosa. |
2001-03-29 |
2023-08-12 |
Not clear |
| H Steiger, S N Young, N M Kin, N Koerner, M Israel, P Lageix, J Pari. Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa. Psychological medicine. vol 31. issue 1. 2001-03-29. PMID:11200963. |
bulimic, impulsive and depressive syndromes have all been associated with abnormalities in brain serotonin (5-hydroxytryptamine; 5-ht) mechanisms. |
2001-03-29 |
2023-08-12 |
Not clear |
| J Evans, B Reeves, H Platt, A Leibenau, D Goldman, K Jefferson, D Nut. Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH). Psychological medicine. vol 30. issue 6. 2001-02-22. PMID:11097073. |
impulsiveness, serotonin genes and repetition of deliberate self-harm (dsh). |
2001-02-22 |
2023-08-12 |
Not clear |
| J Evans, B Reeves, H Platt, A Leibenau, D Goldman, K Jefferson, D Nut. Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH). Psychological medicine. vol 30. issue 6. 2001-02-22. PMID:11097073. |
serotonin function has been linked to impulsive and suicidal behaviour and genetic polymorphisms have been identified within the serotonin system that could account for this link. |
2001-02-22 |
2023-08-12 |
Not clear |
| D R Cherek, S D Lan. Fenfluramine effects on impulsivity in a sample of adults with and without history of conduct disorder. Psychopharmacology. vol 152. issue 2. 2001-02-08. PMID:11057518. |
the role of serotonin in impulsivity was examined by administering the serotonin-releasing drug, d,l-fenfluramine, and measuring effects on impulsive responding of male subjects with and without a history of conduct disorder (cd) under controlled laboratory conditions. |
2001-02-08 |
2023-08-12 |
human |
| K P Lesch, U Merschdor. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behavioral sciences & the law. vol 18. issue 5. 2001-02-08. PMID:11113963. |
impulsivity, aggression, and serotonin: a molecular psychobiological perspective. |
2001-02-08 |
2023-08-12 |
mouse |
| K P Lesch, U Merschdor. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behavioral sciences & the law. vol 18. issue 5. 2001-02-08. PMID:11113963. |
although special emphasis is given to the molecular psychobiology of 5ht in aggression-related behavior in rodents, nonhuman primates, and humans, relevant conceptual and methodological issues in the search for candidate genes for impulsivity and aggressiveness and for the development of mouse models of aggressive and antisocial behavior in humans are also considered. |
2001-02-08 |
2023-08-12 |
mouse |
| A K Johansson, S Hanse. Increased alcohol intake and behavioral disinhibition in rats with ventral striatal neuron loss. Physiology & behavior. vol 70. issue 5. 2001-02-01. PMID:11110998. |
a previous study of ours reported excessive alcohol intake, enhanced defensive aggressiveness (hyperreactivity towards the experimenter), impulsive behavior, and reduced cortical serotonin levels in rats following extensive basal forebrain axon-sparing lesions involving the septal area and the ventral striatum. |
2001-02-01 |
2023-08-12 |
rat |
| E Hollander, J Rose. Impulsivity. Journal of psychopharmacology (Oxford, England). vol 14. issue 2 Suppl 1. 2000-11-16. PMID:10888030. |
the link between serotonergic dysfunction and the pathophysiology of impulsivity is discussed, and studies that examine the efficacy of various selective serotonin reuptake inhibitors and other alternatives in the treatment of impulsive disorders such as pathological gambling, sexual addictions and borderline personality disorder are presented. |
2000-11-16 |
2023-08-12 |
Not clear |
| b' T Koskinen, S Ruotsalainen, J Sirvi\\xc3\\xb. The 5-HT(2) receptor activation enhances impulsive responding without increasing motor activity in rats. Pharmacology, biochemistry, and behavior. vol 66. issue 4. 2000-11-07. PMID:10973510.' |
the 5-ht(2) receptor activation enhances impulsive responding without increasing motor activity in rats. |
2000-11-07 |
2023-08-12 |
rat |
| S M Dursun, A Szemis, H Andrews, P Whitaker, M A Revele. Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study. Journal of psychiatry & neuroscience : JPN. vol 25. issue 4. 2000-11-07. PMID:11022399. |
effects of clozapine and typical antipsychotic drugs on plasma 5-ht turnover and impulsivity in patients with schizophrenia: a cross-sectional study. |
2000-11-07 |
2023-08-12 |
Not clear |
| S M Dursun, A Szemis, H Andrews, P Whitaker, M A Revele. Effects of clozapine and typical antipsychotic drugs on plasma 5-HT turnover and impulsivity in patients with schizophrenia: a cross-sectional study. Journal of psychiatry & neuroscience : JPN. vol 25. issue 4. 2000-11-07. PMID:11022399. |
to compare the efficacy of clozapine with typical antipsychotic drugs in controlling impulsivity and to explore the possible correlation of impulsivity with plasma 5-hydroxytryptamine (5-ht) levels, plasma 5-hydroxyindoleacetic acid (5-hiaa) levels and plasma 5-ht turnover. |
2000-11-07 |
2023-08-12 |
Not clear |
| U W Preuss, M Soyka, M Bahlmann, K Wenzel, S Behrens, S de Jonge, M Krüger, B Bond. Serotonin transporter gene regulatory region polymorphism (5-HTTLPR), [3H]paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity. Psychiatry research. vol 96. issue 1. 2000-10-31. PMID:10980326. |
serotonin transporter gene regulatory region polymorphism (5-httlpr), [3h]paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity. |
2000-10-31 |
2023-08-12 |
human |
| U W Preuss, M Soyka, M Bahlmann, K Wenzel, S Behrens, S de Jonge, M Krüger, B Bond. Serotonin transporter gene regulatory region polymorphism (5-HTTLPR), [3H]paroxetine binding in healthy control subjects and alcohol-dependent patients and their relationships to impulsivity. Psychiatry research. vol 96. issue 1. 2000-10-31. PMID:10980326. |
the aim of this study was to investigate [3h]paroxetine binding and impulsivity in alcohol-dependent and age-matched control subjects in relation to a 5'-promoter region serotonin transporter (5-htt) polymorphism (5-httlpr). |
2000-10-31 |
2023-08-12 |
human |