| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rémy Burcelin, Marc Uldry, Marc Foretz, Christophe Perrin, Anabela Dacosta, Monique Nenniger-Tosato, Josiane Seydoux, Susanna Cotecchia, Bernard Thoren. Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype. The Journal of biological chemistry. vol 279. issue 2. 2004-02-10. PMID:14581480. |
altogether, our results indicate that in the absence of the alpha1b-ar the expression of hypotalamic npy and the parasympathetic nervous activity are both increased resulting in hyperinsulinemia and insulin resistance as well as favoring obesity and glucose intolerance development during high fat feeding. |
2004-02-10 |
2023-08-12 |
mouse |
| Robert H Knopp, Barbara Retzlaff, Brian Fish, Carolyn Walden, Shari Wallick, Melissa Anderson, Keiko Aikawa, Steven E Kah. Effects of insulin resistance and obesity on lipoproteins and sensitivity to egg feeding. Arteriosclerosis, thrombosis, and vascular biology. vol 23. issue 8. 2004-01-29. PMID:12816878. |
effects of insulin resistance and obesity on lipoproteins and sensitivity to egg feeding. |
2004-01-29 |
2023-08-12 |
Not clear |
| M Vestergaard, S Purup, J Frystyk, P Løvendahl, M T Sørensen, P M Riis, D J Flint, K Sejrse. Effects of growth hormone and feeding level on endocrine measurements, hormone receptors, muscle growth and performance of prepubertal heifers. Journal of animal science. vol 81. issue 9. 2004-01-29. PMID:12968693. |
the high feeding level increased insulin, free and total igf-i, and igfbp-3 (all p < 0.001), but decreased gh and igfbp-2 (both p < 0.001). |
2004-01-29 |
2023-08-12 |
Not clear |
| R M Hoffman, R C Boston, D Stefanovski, D S Kronfeld, P A Harri. Obesity and diet affect glucose dynamics and insulin sensitivity in Thoroughbred geldings. Journal of animal science. vol 81. issue 9. 2004-01-29. PMID:12968709. |
feeding a diet rich in sugar and starch decreased insulin sensitivity of horses. |
2004-01-29 |
2023-08-12 |
Not clear |
| James E Jordan, Steven A Simandle, Christina D Tulbert, David W Busija, Allison W Mille. Fructose-fed rats are protected against ischemia/reperfusion injury. The Journal of pharmacology and experimental therapeutics. vol 307. issue 3. 2004-01-29. PMID:14534360. |
this study examines the relationship between insulin resistance (ir) induced by fructose feeding (ff) and susceptibility to myocardial ischemia/reperfusion injury (mi/r). |
2004-01-29 |
2023-08-12 |
rat |
| V Thirunavukkarasu, A T Anitha Nandhini, C V Anuradh. Lipoic acid restores antioxidant system in tissues of hyperinsulinaemic rats. The Indian journal of medical research. vol 118. 2004-01-23. PMID:14700347. |
feeding rats with high fructose induces insulin resistance, hyperinsulinaemia, elevation of blood glucose level and impaired glucose tolerance. |
2004-01-23 |
2023-08-12 |
rat |
| G Marchesini, U Pagotto, E Bugianesi, R De Iasio, R Manini, E Vanni, R Pasquali, N Melchionda, M Rizzett. Low ghrelin concentrations in nonalcoholic fatty liver disease are related to insulin resistance. The Journal of clinical endocrinology and metabolism. vol 88. issue 12. 2004-01-15. PMID:14671152. |
several physiological and pathophysiological conditions, including changes in body fat, food intake, and insulin resistance, are known to be associated with variations in plasma ghrelin concentrations. |
2004-01-15 |
2023-08-12 |
human |
| Stephen C Benoit, Deborah J Clegg, Jason G Barrera, Randy J Seeley, Stephen C Wood. Learned meal initiation attenuates the anorexic effects of the melanocortin agonist MTII. Diabetes. vol 52. issue 11. 2004-01-14. PMID:14578286. |
administration of melanocortin agonists reduces food intake and adiposity, and the central melanocortin system is demonstrated to mediate the anorexic effects of both leptin and insulin. |
2004-01-14 |
2023-08-12 |
rat |
| I Vervuert, M Coenen, C Both. Effects of oat processing on the glycaemic and insulin responses in horses. Journal of animal physiology and animal nutrition. vol 87. issue 3-4. 2004-01-05. PMID:14511133. |
oat feeding resulted in a significant increase in mean plasma glucose and insulin concentration. |
2004-01-05 |
2023-08-12 |
Not clear |
| I Vervuert, M Coenen, C Both. Effects of oat processing on the glycaemic and insulin responses in horses. Journal of animal physiology and animal nutrition. vol 87. issue 3-4. 2004-01-05. PMID:14511133. |
the insulin reaction to oat feeding showed a high variability between the horses. |
2004-01-05 |
2023-08-12 |
Not clear |
| Jing-Ning Huan, Ji Li, Yiping Han, Ke Chen, Nancy Wu, Allan Z Zha. Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance. The Journal of biological chemistry. vol 278. issue 46. 2003-12-24. PMID:12925533. |
despite a normal level of leptin receptors in the hypothalamus and normal food intake, mutant mice developed increased adiposity, decreased body temperature, hyperinsulinemia, hypertriglyceridemia, impaired glucose tolerance and insulin sensitivity, as well as elevated hepatic and skeletal muscle triglyceride levels. |
2003-12-24 |
2023-08-12 |
mouse |
| Jing-Ning Huan, Ji Li, Yiping Han, Ke Chen, Nancy Wu, Allan Z Zha. Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance. The Journal of biological chemistry. vol 278. issue 46. 2003-12-24. PMID:12925533. |
furthermore, the mutant mice are significantly more sensitive to high fat feeding with regard to developing obesity and severe insulin resistance. |
2003-12-24 |
2023-08-12 |
mouse |
| Naruhiro Fujita, Hiroyuki Sakamaki, Shigeo Uotani, Ryoko Takahashi, Hironaga Kuwahara, Atsushi Kita, Katsuya Oshima, Hironori Yamasaki, Yoshihiko Yamaguchi, Katsumi Eguch. Intracerebroventricular administration of insulin and glucose inhibits the anorectic action of leptin in rats. Experimental biology and medicine (Maywood, N.J.). vol 228. issue 10. 2003-12-23. PMID:14610254. |
high insulin or glucose levels in the brain could result in leptin resistance as manifested by food intake, which is probably due to the attenuation of stat3 phosphorylation downstream the leptin receptor. |
2003-12-23 |
2023-08-12 |
human |
| Bernard Thoren. [Gluco-incretin hormones in insulin secretion and diabetes]. Medecine sciences : M/S. vol 19. issue 8-9. 2003-12-19. PMID:14593618. |
although the beta cell secretory response is mainly controlled by blood glucose levels, gut hormones secreted in response to food intake have an important role in potentiating glucose-stimulated insulin secretion. |
2003-12-19 |
2023-08-12 |
Not clear |
| Norika Tamaya-Mori, Kazumasa Uemura, Shin Tanaka, Akihisa Iguch. Aging accelerates dietary lard-induced increase in blood pressure in rats. Experimental gerontology. vol 38. issue 8. 2003-12-15. PMID:12915212. |
after 4 weeks of lard feeding, increases in sbp, plasma insulin, leptin level, sspg and epi-fw/bw were observed in the older lard-fed group. |
2003-12-15 |
2023-08-12 |
rat |
| Charles Plut, Catherine Ribière, Yves Giudicelli, Jean-Pierre Dauss. Hypothalamic leptin receptor and signaling molecule expressions in cafeteria diet-fed rats. The Journal of pharmacology and experimental therapeutics. vol 307. issue 2. 2003-12-10. PMID:12966151. |
because hyperinsulinemia was reported to counteract the leptin-induced stimulation of the sympathetic tone and because socs-1 and -3 are potential inhibitors of insulin signaling, our results suggest that the hypothalamic overexpression of socs-1 or socs-3 found in male or t-treated female rats after cafeteria diet feeding could block the negative influence of the hyperinsulinemia on the central pressor action of leptin, thereby contributing to their hypertensive state. |
2003-12-10 |
2023-08-12 |
rat |
| F Tassone, F Broglio, S Destefanis, S Rovere, A Benso, C Gottero, F Prodam, R Rossetto, C Gauna, A J van der Lely, E Ghigo, M Maccari. Neuroendocrine and metabolic effects of acute ghrelin administration in human obesity. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602793. |
ghrelin levels are inversely associated with body mass index (bmi), increased by fasting and decreased by food intake, glucose load, insulin, and somatostatin. |
2003-12-09 |
2023-08-12 |
human |
| J K Ropp, R H Raub, J E Minto. The effect of dietary energy source on serum concentration of insulin-like growth factor-I growth hormone, insulin, glucose, and fat metabolites in weanling horses. Journal of animal science. vol 81. issue 6. 2003-12-08. PMID:12817507. |
there were consistent increases in glucose and insulin in response to feeding on d 0, 30, and 60 for both groups. |
2003-12-08 |
2023-08-12 |
Not clear |
| J K Ropp, R H Raub, J E Minto. The effect of dietary energy source on serum concentration of insulin-like growth factor-I growth hormone, insulin, glucose, and fat metabolites in weanling horses. Journal of animal science. vol 81. issue 6. 2003-12-08. PMID:12817507. |
on d 60, the insulin response to feeding was less (p < 0.05) over time in fat compared with carb; however, there was no treatment x time effect on d 0 or 30. |
2003-12-08 |
2023-08-12 |
Not clear |
| J K Ropp, R H Raub, J E Minto. The effect of dietary energy source on serum concentration of insulin-like growth factor-I growth hormone, insulin, glucose, and fat metabolites in weanling horses. Journal of animal science. vol 81. issue 6. 2003-12-08. PMID:12817507. |
fat substitution increased serum chol and variably affected serum gh, glucose, and insulin concentrations in response to feeding. |
2003-12-08 |
2023-08-12 |
Not clear |