| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
brain insulin and feeding: a bi-directional communication. |
2004-11-03 |
2023-08-12 |
Not clear |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
this review highlights the complex regulatory loop between dietary nutrients, brain insulin and feeding. |
2004-11-03 |
2023-08-12 |
Not clear |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
it is well documented that brain insulin has a negative, anorexigenic effect on food intake. |
2004-11-03 |
2023-08-12 |
Not clear |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
at present, a specific role for brain insulin on cognitive functions related to feeding is emerging. |
2004-11-03 |
2023-08-12 |
Not clear |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
leptin and melanocortins, peptides that down regulate food intake and are largely affected by nutrients, are highly interactive with insulin in the cns probably via the neurotransmitter serotonin. |
2004-11-03 |
2023-08-12 |
Not clear |
| K Gerozissi. Brain insulin and feeding: a bi-directional communication. European journal of pharmacology. vol 490. issue 1-3. 2004-11-03. PMID:15094073. |
in the hypothalamus, insulin and leptin share a common signaling pathway involved in food intake, namely the insulin receptor substrate, phosphatidylinositol 3-kinase pathway. |
2004-11-03 |
2023-08-12 |
Not clear |
| Loretta L Nielsen, Andrew A Young, David G Parke. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regulatory peptides. vol 117. issue 2. 2004-11-02. PMID:14700743. |
evidence suggests that these agents use a combination of mechanisms which may include glucose-dependent stimulation of insulin secretion, suppression of glucagon secretion, enhancement of beta-cell mass, slowing of gastric emptying, inhibition of food intake, and modulation of glucose trafficking in peripheral tissues. |
2004-11-02 |
2023-08-12 |
Not clear |
| Yasushi Sakai, Koji Nobe, Yoshiaki Maruyama, Kazutaka Momose, Ikuo Homm. A traditional herbal medicine, rikkunshi-to (TJ-43), prevents intracellular signaling disorders in gastric smooth muscle of diabetic rats. The American journal of Chinese medicine. vol 32. issue 2. 2004-11-02. PMID:15315262. |
however, oral administration of tj-43 (1% of food intake) or subcutaneous insulin injection (12 units/kg/day) in streptozotocin-induced diabetic rats (dm) for 2 weeks prevented dgk abnormalities based on the control level. |
2004-11-02 |
2023-08-12 |
rat |
| Manfred Hallschmid, Bernd Schultes, Lisa Marshall, Matthias Mölle, Werner Kern, Julia Bredthauer, Horst L Fehm, Jan Bor. Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain. Diabetes. vol 53. issue 9. 2004-10-26. PMID:15331528. |
circulating insulin is thought to provide a major feedback signal for the hypothalamic regulation of energy homeostasis and food intake, although this signaling appears to be slowed by a time-consuming blood-to-brain transport. |
2004-10-26 |
2023-08-12 |
human |
| Josep A Villena, Benoit Viollet, Fabrizzio Andreelli, Axel Kahn, Sophie Vaulont, Hei Sook Su. Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit. Diabetes. vol 53. issue 9. 2004-10-26. PMID:15331533. |
unlike impaired glucose homeostasis observed on normal diet feeding, when fed a high-fat diet ampkalpha2 ko mice did not show differences in glucose tolerance and insulin sensitivity compared with wild-type mice. |
2004-10-26 |
2023-08-12 |
mouse |
| Laurie L Baggio, Qingling Huang, Theodore J Brown, Daniel J Drucke. A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis. Diabetes. vol 53. issue 9. 2004-10-26. PMID:15331566. |
albugon decreased glycemic excursion and stimulated insulin secretion in wild-type but not glp-1r(-/-) mice and reduced food intake after both intracerebroventricular and intraperitoneal administration. |
2004-10-26 |
2023-08-12 |
mouse |
| John W Bullen, Mary Ziotopoulou, Linda Ungsunan, Jatin Misra, Ilias Alevizos, Efi Kokkotou, Eleftheria Maratos-Flier, Gregory Stephanopoulos, Christos S Mantzoro. Short-term resistance to diet-induced obesity in A/J mice is not associated with regulation of hypothalamic neuropeptides. American journal of physiology. Endocrinology and metabolism. vol 287. issue 4. 2004-10-26. PMID:15361355. |
on and after 1 wk of high-fat feeding, a/j mice adjusted their food intake to consume the same amount of calories as mice fed a low-fat diet; thus their body weight and insulin, corticosterone, free fatty acid, and glucose levels remained unchanged for 4 wk. |
2004-10-26 |
2023-08-12 |
mouse |
| Misato Kobayashi, Fusayo Io, Takahiro Kawai, Masahiko Nishimura, Tamio Ohno, Fumihiko Hori. SMXA-5 mouse as a diabetic model susceptible to feeding a high-fat diet. Bioscience, biotechnology, and biochemistry. vol 68. issue 1. 2004-10-25. PMID:14745189. |
judging from the hyperinsulinemia in smxa-5, this strain showed insulin resistance, an inability of peripheral tissues to respond to insulin, which was strengthened by feeding with a high-fat diet. |
2004-10-25 |
2023-08-12 |
mouse |
| S P Yadav, V Vats, A C Ammini, J K Grove. Brassica juncea (Rai) significantly prevented the development of insulin resistance in rats fed fructose-enriched diet. Journal of ethnopharmacology. vol 93. issue 1. 2004-10-25. PMID:15182915. |
feeding of fructose rich diet for 30 days resulted in rise in blood glucose by 29.4%, insulin by 101.2% and cholesterol by 26.7% indicating development of insulin resistance. |
2004-10-25 |
2023-08-12 |
rat |
| S P Yadav, V Vats, A C Ammini, J K Grove. Brassica juncea (Rai) significantly prevented the development of insulin resistance in rats fed fructose-enriched diet. Journal of ethnopharmacology. vol 93. issue 1. 2004-10-25. PMID:15182915. |
however, feeding of a fructose diet containing 10% brassica juncea seeds powder for 30 days significantly decreased fasting serum glucose, insulin and cholesterol levels but did not normalize them. |
2004-10-25 |
2023-08-12 |
rat |
| Ana Lydia Sawaya, Paula A Martins, Luciane P Grillo, Telma T Florênci. Long-term effects of early malnutrition on body weight regulation. Nutrition reviews. vol 62. issue 7 Pt 2. 2004-10-22. PMID:15387478. |
in the presence of a relative food intake insufficiency, a higher cortisol:insulin ratio, associated with lower levels of igf-1 will lead to lower muscle gain and linear growth, impaired lypolysis and fat oxidation. |
2004-10-22 |
2023-08-12 |
Not clear |
| Andreas Plageman. 'Fetal programming' and 'functional teratogenesis': on epigenetic mechanisms and prevention of perinatally acquired lasting health risks. Journal of perinatal medicine. vol 32. issue 4. 2004-10-21. PMID:15346812. |
data obtained by our group indicate that elevated insulin concentrations during critical periods of perinatal life may induce a lasting 'malprogramming' of neuroendocrine systems regulating body weight, food intake, and metabolism. |
2004-10-21 |
2023-08-12 |
Not clear |
| R S Patton, C E Sorenson, A R Hippe. Effects of dietary glucogenic precursors and fat on feed intake and carbohydrate status of transition dairy cows. Journal of dairy science. vol 87. issue 7. 2004-10-15. PMID:15328225. |
feeding glucose precursors in combination with rumen inert lipids, compared with feeding barley in combination with the lipids for 2 wk before parturition and 3 wk postpartum helped avoid prepartum feed intake depression and increased blood glucose and insulin and decreased blood nefa. |
2004-10-15 |
2023-08-12 |
Not clear |
| Tracy Ann Perry, Nigel H Grei. A new Alzheimer's disease interventive strategy: GLP-1. Current drug targets. vol 5. issue 6. 2004-10-14. PMID:15270203. |
glp-1 receptor stimulation enhances pancreatic islet beta-cell proliferation, glucose-dependent insulin secretion and lowers blood glucose and food intake in patients with type 2 diabetes mellitus. |
2004-10-14 |
2023-08-12 |
mouse |
| Mohammad R Rashidi, Soltanali Mahboob, Reza Sattarivan. Effects of nibbling and gorging on lipid profiles, blood glucose and insulin levels in healthy subjects. Saudi medical journal. vol 24. issue 9. 2004-10-07. PMID:12973474. |
the aim of the present study is to investigate the effects of feeding frequency on blood lipids, glucose and insulin. |
2004-10-07 |
2023-08-12 |
human |