| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tetsushi Nasu, Ryoko Suzuki, Yoshihisa Okamoto, Kaori Miyata, Akiko Uno, Ryutaro Nakao, Akira Kawashima, Taisei Nakao, Michi Kond. Late postprandial hypoglycemia due to bioactive insulin dissociation from autoantibody leading to unconsciousness in a patient with insulin autoimmune syndrome. Internal medicine (Tokyo, Japan). vol 50. issue 4. 2011-06-14. PMID:21325768. |
reactive hypoglycemia occurred due to immediate association followed by dissociation between insulin and insulin autoantibodies after glucose or food intake. |
2011-06-14 |
2023-08-12 |
Not clear |
| W Wayne Lautt, Joshua Schafer, M Paula Macedo, Dallas J Legar. Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats. Canadian journal of physiology and pharmacology. vol 89. issue 2. 2011-06-09. PMID:21326345. |
bethanechol and n-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats. |
2011-06-09 |
2023-08-12 |
rat |
| W Wayne Lautt, Joshua Schafer, M Paula Macedo, Dallas J Legar. Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats. Canadian journal of physiology and pharmacology. vol 89. issue 2. 2011-06-09. PMID:21326345. |
in the presence of two "feeding signals," a pulse of insulin results in the release of hiss from the liver. |
2011-06-09 |
2023-08-12 |
rat |
| W Wayne Lautt, Joshua Schafer, M Paula Macedo, Dallas J Legar. Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats. Canadian journal of physiology and pharmacology. vol 89. issue 2. 2011-06-09. PMID:21326345. |
we tested the hypothesis that provision of both feeding signals allows insulin to cause hiss release in both the normal fasted and the diabetic model. |
2011-06-09 |
2023-08-12 |
rat |
| W Wayne Lautt, Joshua Schafer, M Paula Macedo, Dallas J Legar. Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats. Canadian journal of physiology and pharmacology. vol 89. issue 2. 2011-06-09. PMID:21326345. |
both "feeding signals" are necessary and sufficient for insulin to stimulate hiss release. |
2011-06-09 |
2023-08-12 |
rat |
| Craig W Spellma. Pharmacology of GLP-1 agonists: describing the therapeutic potential to patients. The Journal of the American Osteopathic Association. vol 111. issue 2 Suppl 1. 2011-06-09. PMID:21389294. |
glucagon-like peptide-1 (glp-1) agonists, which improve insulin secretion, decrease glucagon secretion, increase satiety (and therefore decrease food intake), and may have beneficial effects on β-cell function, represent an important addition to treatment options. |
2011-06-09 |
2023-08-12 |
Not clear |
| Ludger Scheja, Barbara Heese, Klaus Seedor. Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice. Biochemical and biophysical research communications. vol 407. issue 2. 2011-06-03. PMID:21371440. |
chronic feeding of a high fat diet induced equal obesity and insulin resistance, and similarly induced inflammatory markers, in ikkε(-/-) and wild-type mice, indicating that under high caloric conditions the inflammatory and metabolic effects of ikkε deficiency were overridden. |
2011-06-03 |
2023-08-12 |
mouse |
| Meena Asma. New physiological effects of the incretin hormones GLP-1 and GIP. Danish medical bulletin. vol 58. issue 2. 2011-06-02. PMID:21299928. |
currently, it is not known whether the inhibiting effects of glp-1 on gastric emptying, appetite and food intake are directly mediated by glp-1, or if the effects are secondary to the robust insulin responses, and thereby amylin responses, elicited by glp-1. |
2011-06-02 |
2023-08-12 |
Not clear |
| Robert C Cooksey, Donald A McClai. Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. Amino acids. vol 40. issue 3. 2011-05-24. PMID:20658157. |
increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. |
2011-05-24 |
2023-08-12 |
mouse |
| Robert C Cooksey, Donald A McClai. Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. Amino acids. vol 40. issue 3. 2011-05-24. PMID:20658157. |
we report here that hexosamine-induced insulin resistance is not additive with that induced by high fat feeding. |
2011-05-24 |
2023-08-12 |
mouse |
| Chen Li, Peter M Jones, Shanta J Persau. Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas. Pharmacology & therapeutics. vol 129. issue 3. 2011-05-19. PMID:21055418. |
we propose that under normal physiological conditions cannabinoid signalling in the endocrine pancreas is a bona fide mechanism of regulating insulin secretion to maintain blood glucose levels, but that energy balance becomes dysregulated with excessive food intake, leading to adipogenesis and fat accumulation through enhanced cannabinoid synthesis. |
2011-05-19 |
2023-08-12 |
Not clear |
| Ruth Vilà, Cristina Cabot, Laura Villarreal, Ana Monegal, Eva Ayet, María del Mar Romero, Maria del Mar Grasa, Montserrat Esteve, José Antonio Fernández-López, Xavier Remesar, Marià Aleman. Oleoyl-estrone is a precursor of an estrone-derived ponderostat signal. The Journal of steroid biochemistry and molecular biology. vol 124. issue 3-5. 2011-05-19. PMID:21310232. |
oleoyl-estrone (oe) is a powerful anti-obesity compound that decreases food intake, decreases insulin resistance and circulating cholesterol. |
2011-05-19 |
2023-08-12 |
rat |
| Jonathan R S Arc. Thermogenesis and related metabolic targets in anti-diabetic therapy. Handbook of experimental pharmacology. issue 203. 2011-05-18. PMID:21484574. |
cannabinoid 1-receptor antagonists and β-adrenoceptor agonists improve insulin sensitivity in humans and promote fat oxidation in rodents independently of reduced food intake. |
2011-05-18 |
2023-08-12 |
human |
| A E Radunz, F L Fluharty, H N Zerby, S C Loerc. Winter-feeding systems for gestating sheep I. Effects on pre- and postpartum ewe performance and lamb progeny preweaning performance. Journal of animal science. vol 89. issue 2. 2011-05-12. PMID:21262977. |
plasma glucose concentrations were greater (p ≤ 0.004) in ewes fed cn than in those fed hl or ddgs just before feeding on d 80 and 122 of gestation, whereas ewes fed ddgs vs. cn or hl had greater (p ≤ 0.04) plasma insulin concentrations at 3 h postfeeding. |
2011-05-12 |
2023-08-12 |
Not clear |
| C E Ash, B J Merr. The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation. Mechanisms of ageing and development. vol 132. issue 1-2. 2011-05-09. PMID:21172374. |
the adenine nucleotide translocase (ant) was shown to be the dominant proton leak channel induced under dr feeding regimes in these tissues, while in brown fat mitochondria, ucp1 was activated, but this was not sensitive to exogenous insulin treatment. |
2011-05-09 |
2023-08-12 |
Not clear |
| C E Ash, B J Merr. The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation. Mechanisms of ageing and development. vol 132. issue 1-2. 2011-05-09. PMID:21172374. |
mobilisation of nefa under dr feeding, when insulin plasma concentrations are extremely low, explains the indirect action of insulin to counteract the effects of dr feeding on mitochondrial ros generation. |
2011-05-09 |
2023-08-12 |
Not clear |
| J E de Leeuw van Weenen, H E Auvinen, E T Parlevliet, C P Coomans, J P Schröder-van der Elst, O C Meijer, H Pij. Blocking dopamine D2 receptors by haloperidol curtails the beneficial impact of calorie restriction on the metabolic phenotype of high-fat diet induced obese mice. Journal of neuroendocrinology. vol 23. issue 2. 2011-05-05. PMID:21062378. |
conversely, high-fat feeding is associated with obesity, insulin resistance and a reduced number of drd2 binding sites. |
2011-05-05 |
2023-08-12 |
mouse |
| Rongjie Yu, Huahua Zhang, Lin Huang, Xiaofei Liu, Jiansu Che. Anti-hyperglycemic, antioxidant and anti-inflammatory effects of VIP and a VPAC1 agonist on streptozotocin-induced diabetic mice. Peptides. vol 32. issue 2. 2011-05-05. PMID:21129425. |
intraperitoneal injection of vip and vpac1 agonist (50nmol/kg/day in saline) over a 28-day period (1) decreased food intake, (2) increased body weight, (3) improved visceral index, (4) increased the fasting plasma insulin levels, (5) decreased the fasting plasma glucose, (6) improved the glucose tolerance, (7) decreased pancreas h(2)o(2) and malondialdehyde (mda) and (8) increased total antioxidant activity (t-aoc) in the liver, spleen and pancreas. |
2011-05-05 |
2023-08-12 |
mouse |
| David W Porter, Nigel Irwin, Peter R Flatt, Christian Hölscher, Victor A Gaul. Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice. European journal of pharmacology. vol 650. issue 2-3. 2011-05-02. PMID:21050845. |
(d-ala(2))gip did not affect food intake or plasma insulin levels irrespective of diet. |
2011-05-02 |
2023-08-12 |
mouse |
| Nishan S Kalupahana, Brynn H Voy, Arnold M Saxton, Naima Moustaid-Mouss. Energy-restricted high-fat diets only partially improve markers of systemic and adipose tissue inflammation. Obesity (Silver Spring, Md.). vol 19. issue 2. 2011-04-29. PMID:20847734. |
restricting intake of the hf diet by 30% (hfr) during the last 2 months of the hf feeding trial decreased fasting plasma insulin, homeostasis model assessment of insulin resistance (homa(ir)), and plasma triglyceride levels and improved hepatic steatosis compared to ad libitum hf feeding, indicating an improved metabolic profile. |
2011-04-29 |
2023-08-12 |
mouse |