| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adrie W Bruijnzeel, Lu W Corrie, Jessica A Rogers, Hidetaka Yamad. Effects of insulin and leptin in the ventral tegmental area and arcuate hypothalamic nucleus on food intake and brain reward function in female rats. Behavioural brain research. vol 219. issue 2. 2011-07-13. PMID:21255613. |
a relatively large increase in insulin or leptin levels in the vta or arc decreases food intake. |
2011-07-13 |
2023-08-12 |
rat |
| Masamitsu Nakazat. [Development of the novel delivery system of GLP-1 administration for the treatment of diabetes mellitus]. Nihon rinsho. Japanese journal of clinical medicine. vol 69. issue 5. 2011-07-08. PMID:21595282. |
glp-1(7-36)nh2 is a major molecular form that stimulates insulin release, reduces food intake, and has a potential to promote beta-cell regeneration. |
2011-07-08 |
2023-08-12 |
Not clear |
| Min Lu, David A Sarruf, Saswata Talukdar, Shweta Sharma, Pingping Li, Gautam Bandyopadhyay, Sarah Nalbandian, WuQiang Fan, Jiaur R Gayen, Sushil K Mahata, Nicholas J Webster, Michael W Schwartz, Jerrold M Olefsk. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature medicine. vol 17. issue 5. 2011-07-05. PMID:21532596. |
hyperinsulinemic euglycemic clamp studies showed that the increase in hepatic insulin sensitivity induced by rosiglitazone treatment during hfd feeding was completely abolished in pparg-bko mice, an effect associated with the failure of rosiglitazone to improve liver insulin receptor signal transduction. |
2011-07-05 |
2023-08-12 |
mouse |
| Timothy H Moran, Ellen E Ladenhei. Adiposity signaling and meal size control. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21110992. |
beginning with seminal studies by woods and colleagues identifying insulin as an adiposity signal, it has become clear that such factors affect food intake by modulating the efficacy of within meal feedback satiety signals. |
2011-07-01 |
2023-08-12 |
Not clear |
| Annette D de Kloet, Gustavo Pacheco-López, Wolfgang Langhans, Lynda M Brow. The effect of TNFα on food intake and central insulin sensitivity in rats. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21163282. |
the effect of tnfα on food intake and central insulin sensitivity in rats. |
2011-07-01 |
2023-08-12 |
rat |
| Annette D de Kloet, Gustavo Pacheco-López, Wolfgang Langhans, Lynda M Brow. The effect of TNFα on food intake and central insulin sensitivity in rats. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21163282. |
the present study evaluated the role of tnfα in the central nervous system control of food intake by insulin in adult male long evans rats. |
2011-07-01 |
2023-08-12 |
rat |
| Annette D de Kloet, Gustavo Pacheco-López, Wolfgang Langhans, Lynda M Brow. The effect of TNFα on food intake and central insulin sensitivity in rats. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21163282. |
subsequently, we assessed the ability of a subthreshold dose of tnfα to modulate the effect of i3vt insulin on food intake in male rats fed a low-fat chow or a high-fat (hf) diet. |
2011-07-01 |
2023-08-12 |
rat |
| Annette D de Kloet, Gustavo Pacheco-López, Wolfgang Langhans, Lynda M Brow. The effect of TNFα on food intake and central insulin sensitivity in rats. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21163282. |
moreover, a low, sub-threshold dose of tnfα diminished the reduction in food intake by insulin in rats maintained on a chow diet, but enhanced insulin action in rats maintained on a hf diet. |
2011-07-01 |
2023-08-12 |
rat |
| Deborah J Clegg, Koro Gotoh, Christopher Kemp, Matthew D Wortman, Stephen C Benoit, Lynda M Brown, David D'Alessio, Patrick Tso, Randy J Seeley, Stephen C Wood. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21241723. |
plasma insulin enters the cns where it interacts with insulin receptors in areas that are related to energy homeostasis and elicits a decrease of food intake and body weight. |
2011-07-01 |
2023-08-12 |
rat |
| Deborah J Clegg, Koro Gotoh, Christopher Kemp, Matthew D Wortman, Stephen C Benoit, Lynda M Brown, David D'Alessio, Patrick Tso, Randy J Seeley, Stephen C Wood. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21241723. |
insulin administered into the 3rd-cerebral ventricle (i3vt) decreased food intake and body weight of lf and chow rats but had no effect on hf rats in either the chronic or the acute experiment. |
2011-07-01 |
2023-08-12 |
rat |
| Deborah J Clegg, Koro Gotoh, Christopher Kemp, Matthew D Wortman, Stephen C Benoit, Lynda M Brown, David D'Alessio, Patrick Tso, Randy J Seeley, Stephen C Wood. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21241723. |
rats chronically pair-fed the hf diet to match the caloric intake of lf rats, and with body weights and adiposity levels comparable to those of lf rats, were also unresponsive to i3vt insulin when returned to ad libitum food whereas rats pair-fed the lf diet had reduced food intake and body weight when administered i3vt insulin. |
2011-07-01 |
2023-08-12 |
rat |
| Deborah J Clegg, Koro Gotoh, Christopher Kemp, Matthew D Wortman, Stephen C Benoit, Lynda M Brown, David D'Alessio, Patrick Tso, Randy J Seeley, Stephen C Wood. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & behavior. vol 103. issue 1. 2011-07-01. PMID:21241723. |
insulin's inability to reduce food intake in the presence of the high-fat diet was associated with a reduced ability of insulin to activate its signaling cascade, as measured by pakt. |
2011-07-01 |
2023-08-12 |
rat |
| François R Jornayvaz, Andreas L Birkenfeld, Michael J Jurczak, Shoichi Kanda, Blas A Guigni, Debbie C Jiang, Dongyan Zhang, Hui-Young Lee, Varman T Samuel, Gerald I Shulma. Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 14. 2011-07-01. PMID:21436037. |
importantly, hepatic insulin resistance in liv-dgat2 mice was independent of differences in body composition, energy expenditure, or food intake. |
2011-07-01 |
2023-08-12 |
mouse |
| Daniel J West, Jeffrey W Stephens, Stephen C Bain, Liam P Kilduff, Stephen Luzio, Rachel Still, Richard M Bracke. A combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus. Journal of sports sciences. vol 29. issue 3. 2011-06-28. PMID:21154013. |
a combined insulin reduction and carbohydrate feeding strategy 30 min before running best preserves blood glucose concentration after exercise through improved fuel oxidation in type 1 diabetes mellitus. |
2011-06-28 |
2023-08-12 |
human |
| Xiaoyan Sheng, Min Wang, Meng Lu, Beili Xi, Hongguang Sheng, Ying Qin Zan. Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice. American journal of physiology. Endocrinology and metabolism. vol 300. issue 5. 2011-06-28. PMID:21364120. |
we found that oral administration of rhein for 40 days significantly increased energy expenditure, reduced body weight, particularly body fat content, improved insulin resistance, and lowered circulating cholesterol levels in dio mice without affecting food intake. |
2011-06-28 |
2023-08-12 |
mouse |
| Kathryn Beardsall, Claire L Pesterfield, Carlo L Acerin. Neonatal diabetes and insulin pump therapy. Archives of disease in childhood. Fetal and neonatal edition. vol 96. issue 3. 2011-06-24. PMID:21115555. |
the need for delivery of small doses of insulin, together with unpredictable feeding patterns and frequent changes in nutrient intake, makes the management of neonatal diabetes challenging. |
2011-06-24 |
2023-08-12 |
Not clear |
| Cristina Lăcătuşu, B Mihai, Cătălina Mihai, Cristina Cijevschi-Prelipcean, Mariana Grau. [Adipocytokines and nonalcoholic steatohepatitis]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 113. issue 2. 2011-06-24. PMID:21495339. |
the most substantial information collected until now concerns the tumor necrosis factor alpha (a proinflammatory cytokine that induces insulin resistance, fat accumulation in the liver and even fibrosis and necrosis), adiponectin (an anti-inflammatory adipokine that acts as an insulin sensitizer and a hepatic protector) and leptin (a signal from the adipose tissue mass with effects on the appetite and food intake, but also acting upon insulin secretion and action and perhaps upon the liver fat accumulation). |
2011-06-24 |
2023-08-12 |
Not clear |
| James S McTaggart, Rebecca H Clark, Frances M Ashcrof. The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. The Journal of physiology. vol 588. issue Pt 17. 2011-06-20. PMID:20519313. |
they are essential for glucose-stimulated insulin secretion from pancreatic beta-cells, contribute to the mechanisms by which hypoglycaemia stimulates glucagon release from pancreatic alpha-cells, and are involved in glucose uptake into skeletal muscle, glucose production and release from the liver, and feeding behaviour. |
2011-06-20 |
2023-08-12 |
Not clear |
| Susana Sangiao-Alvarellos, Steffen Helmling, María J Vázquez, Sven Klussmann, Fernando Cordid. Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism. Molecular and cellular endocrinology. vol 335. issue 2. 2011-06-20. PMID:21241769. |
ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. |
2011-06-20 |
2023-08-12 |
rat |
| P Anagnostis, V G Athyros, F Adamidou, A Panagiotou, M Kita, A Karagiannis, D P Mikhailidi. Glucagon-like peptide-1-based therapies and cardiovascular disease: looking beyond glycaemic control. Diabetes, obesity & metabolism. vol 13. issue 4. 2011-06-17. PMID:21205117. |
glp-1 exerts its glucose-regulatory action via stimulation of insulin secretion and glucagon suppression by a glucose-dependent way, as well as by weight loss via inhibition of gastric emptying and reduction of appetite and food intake. |
2011-06-17 |
2023-08-12 |
human |