| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Terry C Yin, Ayushi Mittal, Paul Buscaglia, Wenxian Li, Julien A Seba. Activation of Amygdala Prokineticin receptor 2 neurons drives the anorexigenic activity of the neuropeptide PK2. The Journal of biological chemistry. 2022-12-20. PMID:36539034. |
while pkr1 and pkr2 are both expressed in the hypothalamus, a central region involved in the control of energy homeostasis, pkr2 is also present in the amygdala, which has recently been shown to regulate food intake in response to several anorexigenic signals. |
2022-12-20 |
2023-08-14 |
Not clear |
| Mariangela Pucci, Claudio D'Addario, Emanuela Micioni Di Bonaventura, Francesca Mercante, Eugenia Annunzi, Federico Fanti, Manuel Sergi, Luca Botticelli, Giacomo Einaudi, Carlo Cifani, Maria Vittoria Micioni Di Bonaventur. Endocannabinoid System Regulation in Female Rats with Recurrent Episodes of Binge Eating. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499556. |
the hypothalamus is a brain region which is sensitive to stress and relevant in motivated behaviors, such as food intake. |
2022-12-11 |
2023-08-14 |
rat |
| Jesús Fernández-Felipe, Lucía L López, Victoria Cano, Enrique Sánchez-Hita, A Belén Sanz, Julie A Chowen, Nuria Del Olmo, Mariano Ruiz-Gayo, Beatriz Merin. Regional specific effect of saturated vs unsaturated fat on leptin receptor signalling in mice brain areas regulating feeding. Neuroscience letters. 2022-12-08. PMID:36481371. |
leptin receptors (lepr) are expressed in brain areas controlling food intake homeostasis, such as the hypothalamus, the hippocampus and the prefrontal cortex. |
2022-12-08 |
2023-08-14 |
mouse |
| Thayana de Oliveira Micheletti, Andressa Cassia Dos Santos, Guilherme Zweig Rocha, Vagner Ramon Rodrigues Silva, Paula Gabriele Fernandes Quaresma, Heloisa Balan Assalin, Felipe Silva Junqueira, Eduardo Rochete Ropelle, Alexandre Gabarra Oliveira, Mario Jose Abdalla Saad, Patricia de Oliveira Prad. Acute exercise reduces feeding by activating IL-6/Tubby axis in the mouse hypothalamus. Frontiers in physiology. vol 13. 2022-12-01. PMID:36452038. |
acute exercise reduces feeding by activating il-6/tubby axis in the mouse hypothalamus. |
2022-12-01 |
2023-08-14 |
mouse |
| Pilar Vigil, Jaime Meléndez, Grace Petkovic, Juan Pablo Del Rí. The importance of estradiol for body weight regulation in women. Frontiers in endocrinology. vol 13. 2022-11-24. PMID:36419765. |
this change in food intake is largely mediated by estradiol, which acts directly upon anorexigenic and orexigenic neurons, largely in the hypothalamus. |
2022-11-24 |
2023-08-14 |
Not clear |
| Huiyuan Kang, Min Lai, Yan'er Yao, Bin Wang, Xin Su, Ye Chen. Novel Insights into the Important Role of Leptin in Modulating the Pathological Development of Fibrotic-related Diseases. Current molecular medicine. 2022-11-22. PMID:36411554. |
leptin, as one of the most important cytokines within the circulation, has been confirmed to play a vital role in the hypothalamus of the central nervous system (cns), which could modulate energy homeostasis by suppressing food intake. |
2022-11-22 |
2023-08-14 |
human |
| Fengyan Meng, Yu Yu, Jinxuan Li, Xingfa Han, Xiaogang Du, Xiaohan Cao, Qiuxia Liang, Anqi Huang, Fanli Kong, Linyan Huang, Xianyin Zeng, Guixian B. Characterization of spexin (SPX) in chickens: molecular cloning, functional analysis, tissue expression and its involvement in appetite regulation. Poultry science. vol 102. issue 1. 2022-11-19. PMID:36402041. |
collectively, our findings not only provide the evidences that spx can act as a satiety factor by orchestrating the expression of key feeding regulators in the chicken hypothalamus but also help to facilitate a better understanding of its functional evolution across vertebrates. |
2022-11-19 |
2023-08-14 |
chicken |
| Guangpin Chu, Hualing Peng, Nana Yu, Yuejin Zhang, Xueling Lin, Yisheng L. Involvement of POMC neurons in LEAP2 regulation of food intake and body weight. Frontiers in endocrinology. vol 13. 2022-11-17. PMID:36387867. |
the effects of ghrelin administration on feeding behavior, body weight, and energy metabolism involve the activation of orexigenic neurons in the arcuate nucleus (arc) of the hypothalamus. |
2022-11-17 |
2023-08-14 |
mouse |
| Isabella Gaziano, Svenja Corneliussen, Nasim Biglari, René Neuhaus, Linyan Shen, Tamara Sotelo-Hitschfeld, Paul Klemm, Lukas Steuernagel, Alain J De Solis, Weiyi Chen, F Thomas Wunderlich, Peter Kloppenburg, Jens C Brünin. Dopamine-inhibited POMCDrd2+ neurons in the ARC acutely regulate feeding and body temperature. JCI insight. vol 7. issue 21. 2022-11-08. PMID:36345942. |
dopamine acts on neurons in the arcuate nucleus (arc) of the hypothalamus, which controls homeostatic feeding responses. |
2022-11-08 |
2023-08-14 |
mouse |
| Lei Zhao, Yanling Ding, Chaoyun Yang, Pengfei Wang, Zhiyan Zhao, Ying Ma, Yuangang Shi, Xiaolong Kan. Identification and characterization of hypothalamic circular RNAs associated with bovine residual feed intake. Gene. vol 851. 2022-11-07. PMID:36341726. |
as the core center of regulation of animal feeding, the hypothalamus is closely associated with rfi. |
2022-11-07 |
2023-08-14 |
cattle |
| Lei Zhao, Yanling Ding, Chaoyun Yang, Pengfei Wang, Zhiyan Zhao, Ying Ma, Yuangang Shi, Xiaolong Kan. Identification and characterization of hypothalamic circular RNAs associated with bovine residual feed intake. Gene. vol 851. 2022-11-07. PMID:36341726. |
the study results illustrate the complex biological functions of the hypothalamus in regulating feed efficiency and showing the potential role of circrnas in the feeding behavior regulation of livestock, which would contributing to expanding the understanding of circrna. |
2022-11-07 |
2023-08-14 |
cattle |
| Yoshimitsu Ouchi, Yoshinori Komaki, Kensuke Shimizu, Natsuki Fukano, Toshihisa Sugino, Jun-Ichi Shiraishi, Vishwajit S Chowdhury, Takashi Bung. Comparison of oral administration of fructose and glucose on food intake and physiological parameters in broiler chicks. Poultry science. vol 102. issue 1. 2022-11-06. PMID:36335736. |
after treatment, measurements of food intake (at 0, 30, and 60 min), and blood glucose as well as insulin concentrations were measured over time; however, diencephalic (hypothalamus) gene expression and plasma metabolites were measured at 30 min. |
2022-11-06 |
2023-08-14 |
Not clear |
| Anzela Niraula, Rachael D Fasnacht, Kelly M Ness, Jeremy M Frey, Sophia A Cuschieri, Mauricio D Dorfman, Joshua P Thale. Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity. Diabetes. 2022-11-01. PMID:36318114. |
prostaglandin e2 (pge2) levels increase in the mediobasal hypothalamus during high fat diet (hfd) feeding, and the pge2 receptor ep4 regulates microglial activation state and phagocytic activity, suggesting a potential role for microglial ep4 signaling in obesity pathogenesis. |
2022-11-01 |
2023-08-14 |
mouse |
| Renli Qi, Jing Wang, Jing Sun, Xiaoyu Qiu, Xin Liu, Qi Wang, Feiyun Yang, Liangpeng Ge, Zuohua Li. The effects of gut microbiota colonizing on the porcine hypothalamus revealed by whole transcriptome analysis. Frontiers in microbiology. vol 13. 2022-10-31. PMID:36312924. |
the hypothalamus integrates the higher nerve center system and functions to regulate energy balance, feeding, biological rhythms and mood. |
2022-10-31 |
2023-08-14 |
Not clear |
| Ken-Yu Hironao, Hitoshi Ashida, Yoko Yamashit. Black soybean seed coat polyphenol ameliorates the abnormal feeding pattern induced by high-fat diet consumption. Frontiers in nutrition. vol 9. 2022-10-27. PMID:36299984. |
high-fat diet (hfd) consumption induces chronic inflammation and microglial accumulation in the mediobasal hypothalamus (mbh), the central regulator of feeding behavior and peripheral metabolism. |
2022-10-27 |
2023-08-14 |
mouse |
| Ken-Yu Hironao, Hitoshi Ashida, Yoko Yamashit. Black soybean seed coat polyphenol ameliorates the abnormal feeding pattern induced by high-fat diet consumption. Frontiers in nutrition. vol 9. 2022-10-27. PMID:36299984. |
in the present study, we found that polyphenols derived from black soybean seed coat (be) significantly ameliorated the accumulation of activated microglia and pro-inflammatory cytokine expression in the arcuate nucleus of the hypothalamus of hfd-fed mice, and restored their feeding pattern to one comparable to that of standard diet-fed mice, thereby ameliorating dio. |
2022-10-27 |
2023-08-14 |
mouse |
| Brett M Culbert, Isaac Y Ligocki, Matthew G Salena, Marian Y L Wong, Ian M Hamilton, Nicholas J Bernier, Sigal Balshin. Galanin expression varies with parental care and social status in a wild cooperatively breeding fish. Hormones and behavior. vol 146. 2022-10-22. PMID:36272180. |
here, we assessed how expression of the galanin system varied in two brain regions, the hypothalamus (which regulates feeding) and the preoptic area (which modulates social behaviours including care) in a wild cichlid fish, neolamprologus pulcher. |
2022-10-22 |
2023-08-14 |
Not clear |
| Yuki Kambe, Thanh Trung Nguyen, Toshiharu Yasaka, Thu Thi Nguyen, Yoshimune Sameshima, Kohei Hashiguchi, Norihito Shintani, Hitoshi Hashimoto, Takashi Kurihara, Atsuro Miyat. The Pivotal Role of Neuropeptide Crosstalk from Ventromedial-PACAP to Dorsomedial-Galanin in the Appetite Regulation in the Mouse Hypothalamus. Molecular neurobiology. 2022-10-17. PMID:36251233. |
on the other hand, galanin is highly expressed in the hypothalamus and has been reported to be involved in feeding regulation. |
2022-10-17 |
2023-08-14 |
mouse |
| Xu Wang, Haohong L. Chronic high-fat diet induces overeating and impairs synaptic transmission in feeding-related brain regions. Frontiers in molecular neuroscience. vol 15. 2022-10-13. PMID:36226318. |
we found that lipid droplets accumulated on the ependyma of the third ventricle (3v), which is surrounded by key areas of the hypothalamus that are involved in feeding. |
2022-10-13 |
2023-08-14 |
mouse |
| Hongyu Wang, Pengke Xia, Zhiyang Lu, Yong Su, Weiyun Zh. Time-restricted feeding affects transcriptomic profiling of hypothalamus in pigs through regulating aromatic amino acids metabolism. Journal of the science of food and agriculture. 2022-10-07. PMID:36207281. |
time-restricted feeding affects transcriptomic profiling of hypothalamus in pigs through regulating aromatic amino acids metabolism. |
2022-10-07 |
2023-08-14 |
Not clear |