| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rahim Ullah, Yi Shen, Yu-Dong Zhou, Junfen F. Perinatal metabolic inflammation in the hypothalamus impairs the development of homeostatic feeding circuitry. Metabolism: clinical and experimental. 2023-08-05. PMID:37543245. |
within the hypothalamus and other brain areas, there exists a wide range of interconnected neuronal populations that regulate various aspects of feeding. |
2023-08-05 |
2023-08-14 |
Not clear |
| Luca Botticelli, Emanuela Micioni Di Bonaventura, Fabio Del Bello, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Alessandro Bonifazi, Carlo Cifani, Maria Vittoria Micioni Di Bonaventur. The Neuromedin U system: pharmacological implications for the treatment of obesity and binge eating behavior. Pharmacological research. 2023-07-30. PMID:37517560. |
in the brain, nmu and nmu-r2 are consistently present in the hypothalamus, commonly recognized as the main "feeding center". |
2023-07-30 |
2023-08-14 |
Not clear |
| Evanthia A Makrygianni, George P Chrouso. Neural Progenitor Cells and the Hypothalamus. Cells. vol 12. issue 14. 2023-07-29. PMID:37508487. |
there is evidence that npcs are also present in the postnatal/adult hypothalamus, a highly conserved brain region involved in the regulation of core homeostatic processes, such as feeding, metabolism, reproduction, neuroendocrine integration and autonomic output. |
2023-07-29 |
2023-08-14 |
Not clear |
| Arash Kamali, Mahdie Hosseini, Anusha Gandhi, John A Lincoln, Khader M Hasa. Unfolding the direct connectivity of the occipital cortex with the hypothalamic, septal and BNST nuclei of the human brain. Brain research. 2023-07-24. PMID:37488033. |
the hypothalamus plays essential roles in the human brain by regulating feeding, fear, aggression, reproductive behaviors, and autonomic activities. |
2023-07-24 |
2023-08-14 |
human |
| Seul Ki Kim, Le Trung Tran, Cherl NamKoong, Hyung Jin Choi, Hye Jin Chun, Yong-Ho Lee, MyungHyun Cheon, ChiHye Chung, Junmo Hwang, Hyun-Ho Lim, Dong Min Shin, Yun-Hee Choi, Ki Woo Ki. Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons. Nature communications. vol 14. issue 1. 2023-07-19. PMID:37468558. |
in addition, the activation of pro-opiomelanocortin (pomc) neurons by shlp2 in the arcuate nucleus of the hypothalamus (arc) is involved in the suppression of food intake and the promotion of thermogenesis. |
2023-07-19 |
2023-08-14 |
mouse |
| Shulan Qiu, Sijia He, Jianing Wang, Hu Wang, Anindita Bhattacharjee, Xin Li, Moawiz Saeed, Jeffrey L Dupree, Xianlin Ha. Adult-Onset CNS Sulfatide Deficiency Causes Sex-Dependent Metabolic Disruption in Aging. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445661. |
mechanistically, we found that increased body weight was associated with increased food intake and elevated neuroinflammation, especially in the hypothalamus, in a sex-specific manner. |
2023-07-14 |
2023-08-14 |
mouse |
| Hyeyoon Eo, Seong Hye Kim, In Gyoung Ju, Eugene Huh, Sinyeon Kim, Jin Gyu Choi, Se Woong Kim, Miwon Son, Myung Sook O. Longan extract suppresses food intake through regulation of POMC/AgRP neuronal activities and endoplasmic reticulum stress in hypothalamus of db/db mice. Frontiers in nutrition. vol 10. 2023-07-07. PMID:37415911. |
longan extract suppresses food intake through regulation of pomc/agrp neuronal activities and endoplasmic reticulum stress in hypothalamus of db/db mice. |
2023-07-07 |
2023-08-14 |
mouse |
| Rachel A Ross, Angela Kim, Priyanka Das, Yan Li, Yong Kee Choi, Andy T Thompson, Ella Douglas, Siva Subramanian, Kat Ramos, Kathryn Callahan, Vadim Y Bolshakov, Kerry J Ressle. Prefrontal cortex melanocortin 4 receptors (MC4R) mediate food intake behavior in male mice. Physiology & behavior. 2023-06-27. PMID:37369302. |
melanocortin 4 receptor (mc4r) activity in the hypothalamus is crucial for regulation of metabolism and food intake. |
2023-06-27 |
2023-08-14 |
mouse |
| Mahardian Rahmadi, Ahmad D Nurhan, Retno I A Rahmawati, Theresia F Damayanti, Djoko A Purwanto, Junaidi Khoti. Epigallocatechin Gallate Ameliorates Nicotine Withdrawal Conditions-Induced Somatic and Affective Behavior Changes in Mice and Its Molecular Mechanism. Behavioural neurology. vol 2023. 2023-06-22. PMID:37346971. |
in nicotine withdrawal (nw) conditions, molecular changes, such as increasing corticotropin-releasing factor (crf) in the amygdala, and melanocortin signaling in the hypothalamus, can occur in the brain, leading to increased feeding behavior and body weight as somatic changes as well as high anxiety-like behavior as an affective changes. |
2023-06-22 |
2023-08-14 |
mouse |
| Rafie Belali, Seyyed Ali Mard, Seyed Esmaeil Khoshnam, Kowsar Bavarsad, Alireza Sarkaki, Yaghoob Farboo. Anandamide improves food intake and orexinergic neuronal activity in the chronic sleep deprivation induction model in rats by modulating the expression of the CB1 receptor in the lateral hypothalamus. Neuropeptides. vol 101. 2023-06-08. PMID:37290176. |
weight gain, food intake, the electrical power of orexin neurons, cb1r mrna expression in hypothalamus, cb1r protein expression in the lh, tnf-α, il-6, il-4 levels and antioxidant activity in hypothalamus were measured after sd induction. |
2023-06-08 |
2023-08-14 |
rat |
| Rafie Belali, Seyyed Ali Mard, Seyed Esmaeil Khoshnam, Kowsar Bavarsad, Alireza Sarkaki, Yaghoob Farboo. Anandamide improves food intake and orexinergic neuronal activity in the chronic sleep deprivation induction model in rats by modulating the expression of the CB1 receptor in the lateral hypothalamus. Neuropeptides. vol 101. 2023-06-08. PMID:37290176. |
our results showed that aea administration significantly improved food intake (p < 0.01), electrical activity of orexin neurons (p < 0.05), cb1r expression in the hypothalamus (p < 0.05), and il-4 levels (p < 0.05). |
2023-06-08 |
2023-08-14 |
rat |
| Kenia L O Cruz, Daniele H Salla, Mariana P Oliveira, Larissa E Silva, Larissa M D Vedova, Talita F Mendes, Catarina B C Bressan, Mariella R Silva, Sheila M L Santos, Hevylin J Soares, Rayane L Mendes, Camila N Vernke, Marina G Silva, Ana O M Laurentino, Fabiana D Medeiros, Thais C Vilela, Isabela Lemos, Rafael M Bitencourt, Gislaine Z Réus, Emilio L Streck, Aline H Mello, Gislaine T Rezi. Energy metabolism and behavioral parameters in female mice subjected to obesity and offspring deprivation stress. Behavioural brain research. 2023-06-04. PMID:37271313. |
thus, it is concluded that obesity and od lead to anhedonia in animals and to mitochondrial dysfunction in the hypothalamus and hippocampus, which may lead to losses in feeding control and cognition of the dams. |
2023-06-04 |
2023-08-14 |
mouse |
| Ruijie Jin, Shanbin Sun, Yang Hu, Hongfei Zhang, Xiangrong Su. Neuropeptides Modulate Feeding via the Dopamine Reward Pathway. Neurochemical research. 2023-05-26. PMID:37233918. |
according to recent literature, neuropeptides released from the hypothalamus and other brain regions regulate reward feeding predominantly through dopaminergic neurons projecting from the vta to the nac. |
2023-05-26 |
2023-08-14 |
Not clear |
| Erika Iervasi, Antonella Strangio, Luigi Greco, Renata Auricchio, Daniele Saverin. Circulating anti-hypothalamus antibodies in celiac patients: tissue transglutaminase friend or foe? Immunologic research. 2023-05-23. PMID:37221348. |
hypothalamus plays a central role in determining eating behaviour, regulating appetite and, consequently, food intake. |
2023-05-23 |
2023-08-14 |
Not clear |
| Clarissa M D Mota, Christopher J Madde. Mediobasal hypothalamic neurons contribute to the control of brown adipose tissue sympathetic nerve activity and cutaneous vasoconstriction. Journal of thermal biology. vol 114. 2023-05-22. PMID:37216765. |
the mediobasal hypothalamus (mbh) contains heterogeneous neuronal populations that regulate food intake and energy expenditure. |
2023-05-22 |
2023-08-14 |
Not clear |
| Emma K McIlwraith, Denise D Belsha. Palmitate alters miR-2137 and miR-503-5p to induce orexigenic Npy in hypothalamic neuronal cell models: Rescue by oleate and docosahexaenoic acid. Journal of neuroendocrinology. 2023-05-20. PMID:37208960. |
palmitate also promotes obesity by acting on the hypothalamus, the central coordinator of energy homeostasis, to dysregulate hypothalamic feeding neuropeptides and induce er stress and inflammatory signaling. |
2023-05-20 |
2023-08-14 |
Not clear |
| Nathan Favalier, Jérôme Roy, Karine Dias, Patrick Maunas, Nicolas Turonnet, Marta Conde-Sieira, Stephane Panserat, José Luis Soengas, Lucie Marande. Sex dimorphism of glucosensing parameters and appetite-regulating peptides in the hypothalamus of rainbow trout broodstocks. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2023-04-21. PMID:37085140. |
therefore, our objective was to assess, for the first time in fish, the short-term consequences in hypothalamus, the glucose sensing and feed intake regulation of feeding mature female and male, and neomale rainbow trout with a diet containing either no or a 33% carbohydrate. |
2023-04-21 |
2023-08-14 |
Not clear |
| Shota Yamamoto, Ryosuke Arakaki, Hiroki Noguchi, Asuka Takeda, Maimi Uchishiba, Shuhei Kamada, Ayuka Mineda, Masafumi Kon, Takako Kawakita, Riyo Kinouchi, Yuri Yamamoto, Kanako Yoshida, Nobuo Shinohara, Takeshi Iwas. New discoveries on the interaction between testosterone and oxytocin in male rats - Testosterone-mediated effects of oxytocin in the prevention of obesity. Physiology & behavior. 2023-04-16. PMID:37062515. |
testosterone also increased the expression of ot receptors in the hypothalamus to increase sensitivity to ot, and perhaps because of this, ot administration had the effect of reducing food intake and body weight gain in both normal and castrated rats, and this effect was stronger in normal rats. |
2023-04-16 |
2023-08-14 |
rat |
| Yong Han, Yang He, Lauren Harris, Yong Xu, Qi W. Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity. eLife. vol 12. 2023-04-12. PMID:37043384. |
the hormone leptin is known to robustly suppress food intake by acting upon the leptin receptor (lepr) signaling system residing within the agouti-related protein (agrp) neurons of the hypothalamus. |
2023-04-12 |
2023-08-14 |
Not clear |
| Jubiao Zhang, Yang Chen, Lihong Yan, Xin Zhang, Xiaoyan Zheng, Junxia Qi, Fen Yang, Juxue L. EphA3 deficiency in the hypothalamus promotes high-fat diet-induced obesity in mice. Journal of biomedical research. 2023-04-04. PMID:37013864. |
in the current study, we demonstrated that the deletion of epha3 in the hypothalamus by crispr/cas9-mediated gene editing promotes obesity in male mice with high-fat diet feeding rather than those with normal chow diet feeding. |
2023-04-04 |
2023-08-14 |
mouse |