| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Sartin, B K Whitlock, J A Danie. Triennial Growth Symposium: neural regulation of feed intake: modification by hormones, fasting, and disease. Journal of animal science. vol 89. issue 7. 2011-11-10. PMID:21148776. |
in addition, satiety signals from the liver and gastrointestinal tract signal through the vagus nerve to the nucleus tractus solitarius to cause meal termination, and in combination with the hypothalamus, integrate the various signals to determine the feeding response. |
2011-11-10 |
2023-08-12 |
Not clear |
| Michelle Murphy, Francis J P Eblin. The role of hypothalamic tri-iodothyronine availability in seasonal regulation of energy balance and body weight. Journal of thyroid research. vol 2011. 2011-11-10. PMID:21765988. |
experimental microimplantation of t3 directly into the hypothalamus during short-days promotes a long-day phenotype by increasing food intake and body weight without affecting the peripheral thyroid axis. |
2011-11-10 |
2023-08-12 |
Not clear |
| Laura M Frago, Eva Baquedano, Jesús Argente, Julie A Chowe. Neuroprotective actions of ghrelin and growth hormone secretagogues. Frontiers in molecular neuroscience. vol 4. 2011-11-10. PMID:21994488. |
ghrelin is a gastric hormone that stimulates growth hormone secretion and food intake to regulate energy homeostasis and body weight by binding to its receptor, growth hormone secretagogues-gh secretagogue-receptor, which is most highly expressed in the pituitary and hypothalamus. |
2011-11-10 |
2023-08-12 |
Not clear |
| Noriyuki Shimizu, Sachiko Chikahisa, Kazuyoshi Kitaoka, Seiji Nishino, Hiroyoshi Sé. Refeeding after a 24-hour fasting deepens NREM sleep in a time-dependent manner. Physiology & behavior. vol 104. issue 3. 2011-11-03. PMID:21605579. |
sleep/wake cycle is regulated by a variety of neuropeptides in the hypothalamus, a brain region that also regulates energy homeostasis and feeding behavior. |
2011-11-03 |
2023-08-12 |
mouse |
| Jessica R Barson, Irene Morganstern, Sarah F Leibowit. Similarities in hypothalamic and mesocorticolimbic circuits regulating the overconsumption of food and alcohol. Physiology & behavior. vol 104. issue 1. 2011-10-14. PMID:21549731. |
historically, studies of food intake regulation started with the hypothalamus and gradually expanded to mesocorticolimbic regions, while studies of drug use began with mesocorticolimbic regions and now include the hypothalamus. |
2011-10-14 |
2023-08-12 |
Not clear |
| Jessica Santollo, Ann-Marie Torregrossa, Lisa A Ecke. Estradiol acts in the medial preoptic area, arcuate nucleus, and dorsal raphe nucleus to reduce food intake in ovariectomized rats. Hormones and behavior. vol 60. issue 1. 2011-10-13. PMID:21439964. |
in order to identify brain regions that are sufficient for e2's anorectic effect, food intake was monitored for 48 h following acute, unilateral, microinfusions of vehicle and two doses (0.25 and 2.5 μg) of a water-soluble form of e2 in multiple brain regions within the hypothalamus and midbrain of ovariectomized rats. |
2011-10-13 |
2023-08-12 |
rat |
| Abhiram Sah. Intracellular leptin-signaling pathways in hypothalamic neurons: the emerging role of phosphatidylinositol-3 kinase-phosphodiesterase-3B-cAMP pathway. Neuroendocrinology. vol 93. issue 4. 2011-10-13. PMID:21464566. |
leptin is secreted primarily by fat cells and acts centrally, particularly in the hypothalamus, to reduce food intake and body weight. |
2011-10-13 |
2023-08-12 |
Not clear |
| Jill S Carmody, Phyllis Wan, Domenico Accili, Lori M Zeltser, Rudolph L Leibe. Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny. Obesity (Silver Spring, Md.). vol 19. issue 3. 2011-10-04. PMID:20948526. |
quantification of proopiomelanocortin (pomc) and neuropeptide-y (npy) populations in the arcuate nucleus of the hypothalamus (arh) of offspring of wild-type vs. insr(+/-) dams was performed to determine whether maternal ir affects the formation of central feeding circuits. |
2011-10-04 |
2023-08-12 |
mouse |
| Joris Wauman, Jan Tavernie. Leptin receptor signaling: pathways to leptin resistance. Frontiers in bioscience (Landmark edition). vol 16. 2011-10-03. PMID:21622208. |
in the hypothalamus, leptin triggers specific neuronal subpopulations, like pomc and agrp/npy neurons, and activates several intracellular signaling events, including the jak/stat, mapk, pi3k and mtor pathway, which eventually translates into decreased food intake and increased energy expenditure. |
2011-10-03 |
2023-08-12 |
Not clear |
| Stefany D Primeau. QRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides. vol 32. issue 6. 2011-09-26. PMID:21473894. |
prepro-qrfp mrna is expressed in localized regions of the mediobasal hypothalamus which are abundant in neurotransmitters, neuropeptides and receptor systems important for food intake regulation and reproductive behaviors. |
2011-09-26 |
2023-08-12 |
rat |
| Takaoki Saneyasu, Kazuhisa Honda, Hiroshi Kamisoyama, Yoko Nakayama, Kengo Ikegami, Shin Hasegaw. Alpha-melanocyte stimulating hormone plays an important role in the regulation of food intake by the central melanocortin system in chicks. Peptides. vol 32. issue 5. 2011-09-23. PMID:21402117. |
proopiomelanocortin (pomc, a precursor of melanocortin peptides) neurons in the hypothalamus play an important role in the central regulation of food intake in mammals. |
2011-09-23 |
2023-08-12 |
human |
| R Orozco-Solís, R J B Matos, S Lopes de Souza, I Grit, B Kaeffer, R Manhães de Castro, F Bolaños-Jiméne. Perinatal nutrient restriction induces long-lasting alterations in the circadian expression pattern of genes regulating food intake and energy metabolism. International journal of obesity (2005). vol 35. issue 7. 2011-09-14. PMID:21060311. |
given the link between the circadian clock and energy metabolism, and the resetting action of food on the circadian clock, in this study, we have investigated whether perinatal undernutrition affects the circadian expression rhythms of genes regulating food intake in the hypothalamus and energy metabolism in the liver. |
2011-09-14 |
2023-08-12 |
Not clear |
| C Catania, E Binder, D Cot. mTORC1 signaling in energy balance and metabolic disease. International journal of obesity (2005). vol 35. issue 6. 2011-09-09. PMID:20877289. |
recent studies have demonstrated that within the central nervous system, and in particular the hypothalamus, mtorc1 represents an essential intracellular target for the actions of hormones and nutrients on food intake and body weight regulation. |
2011-09-09 |
2023-08-12 |
Not clear |
| José Miguel Cerdá-Reverter, Maria Josep Agulleiro, Raúl Guillot R, Elisa Sánchez, Rosa Ceinos, Josep Rotllan. Fish melanocortin system. European journal of pharmacology. vol 660. issue 1. 2011-09-09. PMID:21208603. |
both melanocortin mc(4) and mc(5) receptor are expressed in the hypothalamus, and central melanocortin mc(4) receptor expression is thought to regulate the energy balance through the modulation of feeding behaviour. |
2011-09-09 |
2023-08-12 |
zebrafish |
| Adam Stevens, Ghazala Begum, Anne Whit. Epigenetic changes in the hypothalamic pro-opiomelanocortin gene: a mechanism linking maternal undernutrition to obesity in the offspring? European journal of pharmacology. vol 660. issue 1. 2011-09-09. PMID:21211530. |
thus maternal undernutrition could cause epigenetic changes in the pomc and glucocorticoid receptor genes, in the foetal hypothalamus, which may predispose the offspring to altered regulation of food intake, energy expenditure and glucose homeostasis, later in life. |
2011-09-09 |
2023-08-12 |
Not clear |
| Jun Hou, De-Zhi Zheng, Ji-Yin Zhou, Shi-Wen Zho. Orexigenic effect of cocaine- and amphetamine-regulated transcript (CART) after injection into hypothalamic nuclei in streptozotocin-diabetic rats. Clinical and experimental pharmacology & physiology. vol 37. issue 10. 2011-09-02. PMID:20626417. |
the aim of the present study was to investigate the orexigenic effect of cocaine- and amphetamine-regulated transcript (cart) peptide on feeding regulation following its injection into discrete nuclei of the hypothalamus. |
2011-09-02 |
2023-08-12 |
rat |
| Ligang Zhou, Chen-Yu Yueh, Daniel D Lam, Jill Shaw, Mayowa Osundiji, Alastair S Garfield, Mark Evans, Lora K Heisle. Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons. Behavioural brain research. vol 222. issue 1. 2011-09-02. PMID:21440571. |
here we examine a neurochemical mechanism underlying this effect and report that gsn stimulated food intake is highly correlated with the induction of the neuronal activation marker cfos within two nuclei with a demonstrated role in central glucose sensing and appetite, the arcuate nucleus of the hypothalamus (arc) and lateral hypothalamic area (lha). |
2011-09-02 |
2023-08-12 |
rat |
| Qi-ming Wang, Hui Yang, De-run Tian, Ying Cai, Zhong-nan Wei, Fei Wang, Albert Ch Yu, Ji-sheng Ha. Proteomic analysis of rat hypothalamus revealed the role of ubiquitin-proteasome system in the genesis of DR or DIO. Neurochemical research. vol 36. issue 6. 2011-09-01. PMID:21344186. |
our study reveals that ubiquitin and uchl-1 are obesity-related factors in the hypothalamus that may play an important role in the genesis of dr or dio by interfering with the integrated signaling network that control energy balance and feeding. |
2011-09-01 |
2023-08-12 |
rat |
| Rie Yamamoto, Hiroshi Akazawa, Hiroaki Fujihara, Yukako Ozasa, Noritaka Yasuda, Kaoru Ito, Yoko Kudo, Yingjie Qin, Yoichi Ueta, Issei Komur. Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21525005. |
angiotensin ii type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. |
2011-08-30 |
2023-08-12 |
mouse |
| Rie Yamamoto, Hiroshi Akazawa, Hiroaki Fujihara, Yukako Ozasa, Noritaka Yasuda, Kaoru Ito, Yoko Kudo, Yingjie Qin, Yoichi Ueta, Issei Komur. Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21525005. |
these results thus demonstrate that central at(1) receptor signaling plays a homeostatic role in the regulation of food intake by maintaining gene expression of crh in hypothalamus and suggest a therapeutic potential of central at(1) receptor blockade in feeding disorders. |
2011-08-30 |
2023-08-12 |
mouse |