Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Lucia Caffino, Michel M M Verheij, Lin Que, Chao Guo, Judith R Homberg, Fabio Fumagall. Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30144237. |
serotonin (5-ht) and the habenula (hb) contribute to motivational and emotional states such as depression and drug abuse. |
2020-10-28 |
2023-08-13 |
rat |
Paul A Lapcha. Neuronal Dysregulation in Stroke-Associated Pseudobulbar Affect (PBA): Diagnostic Scales and Current Treatment Options. Journal of neurology & neurophysiology. vol 6. issue 5. 2020-10-01. PMID:26693049. |
pba is now understood to be a disinhibition syndrome in which specific pathways involving serotonin and glutamate are disrupted or modulated causing reduced cortical inhibition of a cerebellar/brainstem-situated "emotional" laughing or crying focal center. |
2020-10-01 |
2023-08-13 |
Not clear |
Rahel Pearson, John McGeary, W Todd Maddox, Christopher G Beever. Serotonin promoter polymorphism (5-HTTLPR) predicts biased attention for emotion stimuli: Preliminary evidence of moderation by the social environment. Clinical psychological science : a journal of the Association for Psychological Science. vol 4. issue 1. 2020-10-01. PMID:26779397. |
serotonin promoter polymorphism (5-httlpr) predicts biased attention for emotion stimuli: preliminary evidence of moderation by the social environment. |
2020-10-01 |
2023-08-13 |
Not clear |
Antonios I Christou, Yvonne Wallis, Hayley Bair, Maurice Zeegers, Joseph P McCleer. Serotonin 5-HTTLPR Genotype Modulates Reactive Visual Scanning of Social and Non-social Affective Stimuli in Young Children. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:28690502. |
previous studies have documented the 5-httlpr polymorphisms as genetic variants that are involved in serotonin availability and also associated with emotion regulation and facial emotion processing. |
2020-09-30 |
2023-08-13 |
human |
Yong Li, Qian Jiao, Xixun Du, Mingxia Bi, Shuaishuai Han, Lingling Jiao, Hong Jian. Investigation of Behavioral Dysfunctions Induced by Monoamine Depletions in a Mouse Model of Parkinson's Disease. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30135645. |
our data highlighted the interactive role of na, 5-ht and da in the motor, emotional and cognitive deficits, providing new insight into the complex orchestration of impaired monoaminergic systems that related to the pathology of pd. |
2020-09-30 |
2023-08-13 |
mouse |
Craig H. Mallinckrodt, David J. Goldstein, Michael J. Detke, Yili Lu, John G. Watkin, Pierre V. Tra. Duloxetine: A New Treatment for the Emotional and Physical Symptoms of Depression. Primary care companion to the Journal of clinical psychiatry. vol 5. issue 1. 2020-09-29. PMID:15156243. |
duloxetine, a dual-reuptake inhibitor of serotonin and norepinephrine, may have a positive effect on physical symptoms in addition to efficacy in treating emotional symptoms of depression. |
2020-09-29 |
2023-08-12 |
Not clear |
Giuseppe Riv. Neurobiology of Anorexia Nervosa: Serotonin Dysfunctions Link Self-Starvation with Body Image Disturbances through an Impaired Body Memory. Frontiers in human neuroscience. vol 10. 2020-09-29. PMID:27932968. |
the review suggests that serotonin disturbances may: (a) facilitate the encoding of third person (allocentric) episodic memories; (b) facilitate the consolidation of emotional episodic memories (e.g., teasing), if preceded by repeated stress; (c) reduce voluntary inhibition of mnestic contents; (d) impair allocentric spatial memory. |
2020-09-29 |
2023-08-13 |
Not clear |
Anne Teissier, Mariano Soiza-Reilly, Patricia Gaspa. Refining the Role of 5-HT in Postnatal Development of Brain Circuits. Frontiers in cellular neuroscience. vol 11. 2020-09-29. PMID:28588453. |
the latter are of particular relevance to understand the impact of transient 5-ht dysfunction during postnatal life on psychiatric illnesses and emotional disorders in adult life. |
2020-09-29 |
2023-08-13 |
mouse |
Xinyang Liu, Andrea Hildebrandt, Guillermo Recio, Werner Sommer, Xinxia Cai, Oliver Wilhel. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence. Frontiers in behavioral neuroscience. vol 11. 2020-09-29. PMID:28848411. |
however, the 5-httlpr/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. |
2020-09-29 |
2023-08-13 |
Not clear |
Andrey V Bocharov, Alexander N Savostyanov, Sergey S Tamozhnikov, Alexander E Saprigyn, Ekaterina A Proshina, Tatiana N Astakhova, Gennady G Knyaze. Impact of Polymorphisms in the Serotonin Transporter Gene on Oscillatory Dynamics during Inhibition of Planned Movement in Children. Brain sciences. vol 9. issue 11. 2020-09-28. PMID:31698879. |
it is known that polymorphisms in the serotonin transporter gene are linked to the dysregulation of emotions. |
2020-09-28 |
2023-08-13 |
human |
Stefano Espinoza, Ilya Sukhanov, Evgeniya V Efimova, Alena Kozlova, Kristina A Antonova, Placido Illiano, Damiana Leo, Natalia Merkulyeva, Daria Kalinina, Pavel Musienko, Anna Rocchi, Liudmila Mus, Tatiana D Sotnikova, Raul R Gainetdino. Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32194374. |
trace amine-associated receptor 5 provides olfactory input into limbic brain areas and modulates emotional behaviors and serotonin transmission. |
2020-09-28 |
2023-08-13 |
mouse |
Frances M Nilsen, Nicolle S Tulv. A systematic review and meta-analysis examining the interrelationships between chemical and non-chemical stressors and inherent characteristics in children with ADHD. Environmental research. vol 180. 2020-09-09. PMID:31706600. |
monoamine oxidase a (maoa) aids in serotonin uptake and is often implicated in behavioral and emotional disorders, including adhd. |
2020-09-09 |
2023-08-13 |
Not clear |
Jenna L Wells, Casey L Brown, Alice Y Hua, Peter D Soyster, Kuan-Hua Chen, Deepika R Dokuru, Giovanni Coppola, Claudia M Haase, Robert W Levenso. Neurodegenerative Disease Caregivers' 5-HTTLPR Genotype Moderates the Effect of Patients' Empathic Accuracy Deficits on Caregivers' Well-Being. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 27. issue 10. 2020-09-02. PMID:31133468. |
to test the hypothesis that a functional polymorphism of the serotonin transporter gene (serotonin-transporter-linked polymorphic region [5-httlpr]), which is thought to be associated with differential environmental sensitivity, moderates the association between low levels of empathic accuracy (i.e., ability to recognize emotions in others) in patients with neurodegenerative disease and caregivers' well-being. |
2020-09-02 |
2023-08-13 |
Not clear |
Eric W Prouty, Daniel J Chandler, Wen-Jun Gao, Barry D Waterhous. Selective vulnerability of dorsal raphe-medial prefrontal cortex projection neurons to corticosterone-induced hypofunction. The European journal of neuroscience. vol 50. issue 1. 2020-08-14. PMID:30687960. |
our results suggest that the serotonergic regulation of cognitive and emotional networks in the mpfc may be more sensitive to the effects of glucocorticoid excess than visual sensory circuits in the lgn and that reduced 5-ht transmission in the mpfc may underlie the association between glucocorticoid excess and depression. |
2020-08-14 |
2023-08-13 |
rat |
Kamyar Khoshnevisan, Elham Honarvarfard, Farzad Torabi, Hassan Maleki, Hadi Baharifar, Farnoush Faridbod, Bagher Larijani, Mohammad Reza Khorramizade. Electrochemical detection of serotonin: A new approach. Clinica chimica acta; international journal of clinical chemistry. vol 501. 2020-07-29. PMID:31715139. |
serotonin (5-hydroxytryptamine, 5-ht) is an important neurotransmitter which plays a significant role in various functions in the body, such as appetite, emotions, and autonomic functions. |
2020-07-29 |
2023-08-13 |
Not clear |
Teresa M Karrer, Casey L McLaughlin, Carmela P Guaglianone, Gregory R Samanez-Larki. Reduced serotonin receptors and transporters in normal aging adults: a meta-analysis of PET and SPECT imaging studies. Neurobiology of aging. vol 80. 2020-04-30. PMID:31055162. |
alterations in serotonin (5-ht) function have been hypothesized to underlie a range of physiological, emotional, and cognitive changes in older age. |
2020-04-30 |
2023-08-13 |
Not clear |
Ji Sun Kim, Do-Won Kim, Young Joon Kwon, Hwa Young Lee, Sungkean Kim, Se Hoon Shi. The relationship between auditory evoked potentials and symptoms of attention-deficit/hyperactivity disorder in adult patients with major depressive disorder. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 142. 2020-04-15. PMID:31207261. |
a recent study has suggested that serotonin plays an important role in impulsivity and emotional sensitivity that are prominent clinical manifestations in attention deficit and hyperactivity disorder (adhd). |
2020-04-15 |
2023-08-13 |
Not clear |
Stephanie M Gorka, Christina B Young, Heide Klumpp, Amy E Kennedy, Jennifer Francis, Olusola Ajilore, Scott A Langenecker, Stewart A Shankman, Michelle G Craske, Murray B Stein, K Luan Pha. Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 9. 2020-03-17. PMID:31060042. |
in this study, we evaluated the utility of three widely used neural probes of emotion (experience, regulation, and perception) in their ability to predict symptom improvement and correlate with symptom change following two first-line treatments-selective serotonin reuptake inhibitors (ssris) and cognitive-behavioral therapy (cbt). |
2020-03-17 |
2023-08-13 |
Not clear |
Yafang Yang, Chunlan Wang, Xiaohan Li, Rongjun Yu, Mengfei Zhang, Mengying Xue, Wenxuan Guo, Linlin He, Xiaocai Gao, Pingyuan Gon. The 5-HTTLPR polymorphism impacts moral permissibility of impersonal harmful behaviors. Social cognitive and affective neuroscience. vol 14. issue 8. 2020-03-09. PMID:31506681. |
inspired by the roles of serotonin in an emotional aversion to harmful actions, we examined to what extent serotonin transporter gene (5-htt)-linked polymorphic region (5-httlpr), a proxy for measuring serotonin function, underpinned the individual differences in moral judgment through cross-sectional analysis and two-wave comparison. |
2020-03-09 |
2023-08-13 |
Not clear |
Luis Javier Ramírez-Jirano, Sandra Fabiola Velasco-Ramírez, Gloria Aleida Pérez-Carranza, Carolina Domínguez-Díaz, Oscar Kurt Bitzer-Quinter. Cytokines and nervous system: relationship with schizophrenia Revista medica del Instituto Mexicano del Seguro Social. vol 57. issue 2. 2020-03-05. PMID:31618565. |
numerous neurotransmitters have been implicated in this disease, as is the case of dopamine, serotonin and glutamate.the role of the inflammatory process in the pathogenesis of schizophrenia has been postulated, where a prenatal immune "challenge" during the second trimester of pregnancy can be key to the development of the disease.some of the pro-inflammatory cytokines (tnf-alpha, il-1beta and il-6) play a key role in the processes of modulation of the nervous system functions related to affective, emotional and social alterations in subjects with schizophrenia.the mechanisms associated with inflammation and the anti-inflammatory defense system that may be associated with the development of schizophrenia are still unknown.this review was intended to address schizophrenia, in regards to the mechanisms associated with inflammation and the anti-inflammatory defense system in its development. |
2020-03-05 |
2023-08-13 |
human |