| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liting Sun, Changgeng Peng, Elbert Joosten, Chi Wai Cheung, Fei Tan, Wencheng Jiang, Xiafeng She. Spinal Cord Stimulation and Treatment of Peripheral or Central Neuropathic Pain: Mechanisms and Clinical Application. Neural plasticity. vol 2021. 2021-11-24. PMID:34721569. |
evidence from recent research publications indicates that nociceptive processing at peripheral and central sensory systems is thought to be modulated by scs through (i) inhibition of the ascending nociceptive transmission by the release of analgesic neurotransmitters such as gaba and endocannabinoids at the spinal dorsal horn; (ii) facilitation of the descending inhibition by release of noradrenalin, dopamine, and serotonin acting on their receptors in the spinal cord; and (iii) activation of a variety of supraspinal brain areas related to pain perception and emotion. |
2021-11-24 |
2023-08-13 |
Not clear |
| Roberto Colangeli, G Campbell Teskey, Giuseppe Di Giovann. Endocannabinoid-serotonin systems interaction in health and disease. Progress in brain research. vol 259. 2021-11-24. PMID:33541682. |
surprising parallelism between the behavioral effects of 5-ht and ecb activity has been widely reported, including the regulation of emotional states, stress homeostasis, cognitive functions, food intake and sleep. |
2021-11-24 |
2023-08-13 |
Not clear |
| B Aboagye, T Weber, H L Merdian, D Bartsch, K P Lesch, J Waide. Serotonin deficiency induced after brain maturation rescues consequences of early life adversity. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33686115. |
brain serotonin (5-ht) system dysfunction is implicated in depressive disorders and acute depletion of 5-ht precursor tryptophan has frequently been used to model the influence of 5-ht deficiency on emotion regulation. |
2021-11-22 |
2023-08-13 |
mouse |
| B Aboagye, T Weber, H L Merdian, D Bartsch, K P Lesch, J Waide. Serotonin deficiency induced after brain maturation rescues consequences of early life adversity. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33686115. |
the impact of tph2 icko in interaction with ms stress (tph2 icko × ms) on physiological parameters, emotional behavior and expression of 5-ht system-related marker genes were assessed. |
2021-11-22 |
2023-08-13 |
mouse |
| V Zamoscik, S N L Schmidt, R Bravo, L Ugartemendia, T Plieger, A B Rodríguez, M Reuter, P Kirsc. Tryptophan-enriched diet or 5-hydroxytryptophan supplementation given in a randomized controlled trial impacts social cognition on a neural and behavioral level. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34737364. |
understanding of emotions and intentions are key processes in social cognition at which serotonin is an important neuromodulator. |
2021-11-08 |
2023-08-13 |
human |
| Jingsheng Gu, Zhijie Hou, Xiaotao Zhou, Qinglei Wang, Yanmei Chen, Jichuan Zhan. Activation of 5-HT Neuroscience letters. 2021-10-26. PMID:34699942. |
activation of 5-ht serotonin (5-hydroxytraptamine, 5-ht) is a neurotransmitter plays important roles in emotion and motivation. |
2021-10-26 |
2023-08-13 |
Not clear |
| Arianna Patacchini, Fiammetta Cosc. Exposure to serotonin selective reuptake inhibitors or serotonin noradrenaline reuptake inhibitors and sexual dysfunction: Results from an online survey. The International journal of risk & safety in medicine. vol 32. issue 3. 2021-10-25. PMID:33579876. |
post-ssri sexual dysfunction (pssd) is characterized by sexual and emotional symptoms associated to the exposure to selective serotonin reuptake inhibitors (ssri) or serotonin noradrenaline reuptake inhibitors (snri). |
2021-10-25 |
2023-08-13 |
Not clear |
| Jeannette M Reid, Eric A Storch, Tanya K Murphy, Danielle Bodzin, P Jane Mutch, Heather Lehmkuhl, Michael Aman, Wayne K Goodma. Development and Psychometric Evaluation of the Treatment-Emergent Activation and Suicidality Assessment Profile. Child & youth care forum. vol 39. issue 2. 2021-10-20. PMID:20473344. |
although effective in treating a range of childhood psychiatric conditions, selective serotonin reuptake inhibitors (ssri) have been implicated in the induction of an "activation syndrome" (characterized by symptoms of irritability, restlessness, emotional labiality, etc.) |
2021-10-20 |
2023-08-12 |
Not clear |
| Marie-Laure Ancelin, Isabelle Carrière, Sylvaine Artero, Jerome J Maller, Chantal Meslin, Anne-Marie Dupuy, Karen Ritchie, Joanne Ryan, Isabelle Chaudie. Structural brain alterations in older adults exposed to early-life adversity. Psychoneuroendocrinology. vol 129. 2021-10-11. PMID:34023732. |
this study examines whether exposure related to physical or sexual maltreatment, emotional maltreatment, and global adverse environment during childhood are associated with specific alterations in grey matter volumes and if this varies according to sex and serotonin transporter-linked promoter region (5-httlpr) genotype. |
2021-10-11 |
2023-08-13 |
Not clear |
| Yéssica P López-Echeverri, Kelly J Cardona-Londoño, Jhonny F Garcia-Aguirre, Mary Orrego-Cardoz. Effects of Serotonin Transporter and Receptor Polymorphisms on Depression. Revista Colombiana de psiquiatria (English ed.). 2021-10-07. PMID:34493397. |
serotonin is highly implicated in the regulation of emotional state and the execution of cognitive tasks, so much so that the serotonin transporter genes (5-htt, slc6a4) and the serotonin receptor genes (htr1a, htr1b, htr2a) have become the perfect candidates when studying the effects that these genes and their polymorphic variations have on depression characteristics. |
2021-10-07 |
2023-08-13 |
Not clear |
| Xiaohong Huang, Shihuan Kuang, Todd J Applegate, Tsang-Long Lin, Heng-Wei Chen. Prenatal Serotonin Fluctuation Affects Serotoninergic Development and Related Neural Circuits in Chicken Embryos. Neuroscience. vol 473. 2021-10-01. PMID:34425158. |
these results may offer a novel sight for understanding the function of 5-ht during neurodevelopment and raise the possibility for using selective 5-ht reuptake inhibitors to regulate emotional and mental wellness during early pregnancy and possible risks of complications for babies. |
2021-10-01 |
2023-08-13 |
chicken |
| Xiaofei Ruan, Suwen Fang, Qi Zheng, Senqing Qi, Yingfang Tian, Wei Re. The Association between 5-Hydroxytryptamine Receptor 1B rs13212041 Polymorphism and Trait Anxiety in Chinese Han College Subjects. Life (Basel, Switzerland). vol 11. issue 9. 2021-10-01. PMID:34575031. |
there is evidence that 5-hydroxytryptamine receptor 1b (5-ht1b) gene polymorphisms play an important role in emotional disorders. |
2021-10-01 |
2023-08-13 |
human |
| Grzegorz Ślifirski, Marek Król, Jadwiga Turł. 5-HT Receptors and the Development of New Antidepressants. International journal of molecular sciences. vol 22. issue 16. 2021-09-28. PMID:34445721. |
serotonin modulates several physiological and cognitive pathways throughout the human body that affect emotions, memory, sleep, and thermal regulation. |
2021-09-28 |
2023-08-13 |
human |
| Iulia Zoicas, Sabine E Huber, Liubov S Kalinichenko, Erich Gulbins, Christian P Müller, Johannes Kornhube. Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region- and ceramide species-specific way in male mice. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31828921. |
our results revealed that c16, but not c8 and c20, ceramide altered alcohol drinking and emotional behavior in a brain region-specific way without altering tissue noradrenaline, dopamine, and serotonin levels in the prefrontal cortex, ventral striatum, and dorsal mesencephalon. |
2021-09-28 |
2023-08-13 |
mouse |
| April Contreras, Matthew Khumnark, Rochelle M Hines, Dustin J Hine. Behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT Scientific reports. vol 11. issue 1. 2021-09-23. PMID:33479368. |
behavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-ht perception, emotion, and mood are powerfully modulated by serotonin receptor (5-htr) agonists including hallucinogens. |
2021-09-23 |
2023-08-13 |
Not clear |
| Vibe G Frokjae. Pharmacological sex hormone manipulation as a risk model for depression. Journal of neuroscience research. vol 98. issue 7. 2021-08-26. PMID:32399989. |
the gnrha model work points to an estradiol-dependent depressive response in healthy women undergoing short-term sex hormone manipulation with gnrha, which is linked to serotonin transporter changes (a key regulator of synaptic serotonin), a disengagement of hippocampus, and overengagement of brain networks recruited when processing emotional salient information. |
2021-08-26 |
2023-08-13 |
human |
| Jung Eun Kim, Sujin Chae, Sungsoo Kim, Yeon-Joo Jung, Myoung-Goo Kang, Won Do Heo, Daesoo Ki. Cerebellar 5HT-2A receptor mediates stress-induced onset of dystonia. Science advances. vol 7. issue 10. 2021-08-26. PMID:33658190. |
while the serotonin (5ht) system is known to control emotional responses to stress, its role in dystonia remains unclear. |
2021-08-26 |
2023-08-13 |
mouse |
| Isabel Ellerbrock, Angelica Sandström, Jeanette Tour, Silvia Fanton, Diana Kadetoff, Martin Schalling, Karin B Jensen, Rouslan Sitnikov, Eva Kose. Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:33980291. |
the neurotransmitter serotonin, involved in the regulation of pain and emotion, is critically regulated by the 5-ht |
2021-08-12 |
2023-08-13 |
human |
| Emmanuelle Courtiol, Edenia C Menezes, Catia M Teixeir. Serotonergic regulation of the dopaminergic system: Implications for reward-related functions. Neuroscience and biobehavioral reviews. vol 128. 2021-08-04. PMID:34139249. |
finally, given the importance of serotonin during development on adult emotion, the effect of abnormal early-life levels of serotonin on the dopaminergic system will also be discussed. |
2021-08-04 |
2023-08-13 |
Not clear |
| Surojit Karmakar, Girdhari La. Role of serotonin receptor signaling in cancer cells and anti-tumor immunity. Theranostics. vol 11. issue 11. 2021-07-28. PMID:33859748. |
serotonin or 5-hydroxytryptamine (5-ht) is a neurotransmitter known to affect emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases. |
2021-07-28 |
2023-08-13 |
Not clear |