| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
this suggests that serotonergic fibers to the thalamus may exert a significant influence on affective and cognitive functions, possibly complementing the actions of 5-ht fibers to other parts of the brain involved in emotional and cognitive behaviors. |
2010-09-23 |
2023-08-12 |
rat |
| Hideki Ohira, Masahiro Matsunaga, Tokiko Isowa, Michio Nomura, Naho Ichikawa, Kenta Kimura, Noriaki Kanayama, Hiroki Murakami, Takahiro Osumi, Toshihiro Konagaya, Tsuyoshi Nogimori, Seisuke Fukuyama, Jun Shinoda, Jitsuhiro Yamad. Polymorphism of the serotonin transporter gene modulates brain and physiological responses to acute stress in Japanese men. Stress (Amsterdam, Netherlands). vol 12. issue 6. 2010-09-20. PMID:19658029. |
a short (s) variant, compared to a long (l) variant, of the promoter region of the serotonin transporter gene-linked polymorphic region (5httlpr) has been related to emotional hyper-reactivity. |
2010-09-20 |
2023-08-12 |
human |
| C Kriegebaum, L Gutknecht, A Schmitt, K-P Lesch, A Rei. [Serotonin now: Part 2. Behavioral genetics and psychopathology]. Fortschritte der Neurologie-Psychiatrie. vol 78. issue 6. 2010-09-08. PMID:20217633. |
several lines of evidence implicate a dysregulation of the serotonin (5-ht) system in emotional behavior and stress, and point to its relevance for the etiology and pathogenesis of various neuropsychiatric disorders. |
2010-09-08 |
2023-08-12 |
mouse |
| C Kriegebaum, L Gutknecht, A Schmitt, K-P Lesch, A Rei. [Serotonin now: Part 1. Neurobiology and developmental genetics]. Fortschritte der Neurologie-Psychiatrie. vol 78. issue 6. 2010-09-08. PMID:20340067. |
5-ht is implicated in a variety of cognitive, emotional and vegetative behaviors, as well as in the regulation of circadian rhythms. |
2010-09-08 |
2023-08-12 |
Not clear |
| M S Man, J W Dalley, A C Robert. Opposing effects of 5,7-DHT infusions into the orbitofrontal cortex and amygdala on flexible responding. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 7. 2010-08-31. PMID:19903764. |
central serotonin is implicated in a variety of emotional and behavioral control processes. |
2010-08-31 |
2023-08-12 |
Not clear |
| Hideyuki Inoue, Hidenori Yamasue, Mamoru Tochigi, Kunio Takei, Motomu Suga, Osamu Abe, Haruyasu Yamada, Mark A Rogers, Shigeki Aoki, Tsukasa Sasaki, Kiyoto Kasa. Effect of tryptophan hydroxylase-2 gene variants on amygdalar and hippocampal volumes. Brain research. vol 1331. 2010-08-20. PMID:20331984. |
these results suggest that amygdalar and hippocampal volumes assessed using mri may be a useful intermediate phenotype that will uncover the biological pathway linking 5-ht synthesis and emotional behaviors and affective disorders. |
2010-08-20 |
2023-08-12 |
human |
| Noelle C Anastasio, Maria Fe Lanfranco, Marcy J Bubar, Patricia K Seitz, Sonja J Stutz, Andrew G McGinnis, Cheryl S Watson, Kathryn A Cunningha. Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20345755. |
utilizing multiples tissues (brain, peripheral tissues), protein fractions (synaptosomal, post-synaptic density), and controls (peptide neutralization, 5-ht(2c)r stably-expressing cells), we established the selectivity of two commercially available 5-ht(2c)r antibodies and employed the antibodies in western blot and immunoprecipitation studies of prefrontal cortex (pfc) and motor cortex, two regions implicated in cognitive, emotional and motor dysfunction. |
2010-08-06 |
2023-08-12 |
rat |
| Sikha Saha, Filomena O Gamboa-Esteves, Trevor F C Batte. Differential distribution of 5-HT 1A and 5-HT 1B-like immunoreactivities in rat central nucleus of the amygdala neurones projecting to the caudal dorsomedial medulla oblongata. Brain research. vol 1330. 2010-08-02. PMID:20226766. |
since 5-ht plays an important role in controlling emotional behaviour and the 5-ht(1a) and 5-ht(1b) receptors have been shown to have distinct roles in the regulation of anxiety and depression, the differential expression of these receptors in cea neurones projecting to the caudal dorsomedial medulla suggests that these projection neurones may act differentially in controlling autonomic expression of emotional behaviour. |
2010-08-02 |
2023-08-12 |
rat |
| Kim Hinkelmann, Laura Dragoi, Julia Gompf, Christoph Muhtz, Cüneyt Demiralay, Alexander Yassouridis, Klaus Wiedemann, Michael Kellne. Decreased recognition of negative affect after selective serotonin reuptake inhibition is dependent on genotype. Psychiatry research. vol 177. issue 3. 2010-07-01. PMID:20381161. |
selective serotonin reuptake inhibitors (ssris) are known to influence the information processing of emotional material in depressed patients and healthy controls. |
2010-07-01 |
2023-08-12 |
Not clear |
| Justin H G Williams, David I Perrett, Gordon D Waiter, Stephen Peche. Differential effects of tryptophan depletion on emotion processing according to face direction. Social cognitive and affective neuroscience. vol 2. issue 4. 2010-06-23. PMID:18985132. |
we therefore hypothesized that brain activity associated with emotional representation, would be more susceptible to manipulation of serotonin function by acute tryptophan depletion (atd) for front-viewed than side-viewed faces, measured using functional imaging (fmri). |
2010-06-23 |
2023-08-12 |
Not clear |
| G S Kranz, S Kasper, R Lanzenberge. Reward and the serotonergic system. Neuroscience. vol 166. issue 4. 2010-06-17. PMID:20109531. |
this review provides an argument for serotonin as a fundamental mediator of emotional, motivational and cognitive aspects of reward representation, which makes it possibly as important as dopamine for reward processing. |
2010-06-17 |
2023-08-12 |
human |
| Christopher G Beevers, Alissa J Ellis, Tony T Wells, John E McGear. Serotonin transporter gene promoter region polymorphism and selective processing of emotional images. Biological psychology. vol 83. issue 3. 2010-06-02. PMID:19715738. |
serotonin transporter gene promoter region polymorphism and selective processing of emotional images. |
2010-06-02 |
2023-08-12 |
Not clear |
| Christopher G Beevers, Alissa J Ellis, Tony T Wells, John E McGear. Serotonin transporter gene promoter region polymorphism and selective processing of emotional images. Biological psychology. vol 83. issue 3. 2010-06-02. PMID:19715738. |
several studies have now documented that the serotonin transporter promoter region (5-httlpr) polymorphism predicts neural response to affective images in brain regions involved in the experience of emotion. |
2010-06-02 |
2023-08-12 |
Not clear |
| Diana Armbruster, Anett Mueller, Alexander Strobel, Clemens Kirschbaum, Klaus-Peter Lesch, Burkhard Brock. Influence of functional tryptophan hydroxylase 2 gene variation and sex on the startle response in children, young adults, and older adults. Biological psychology. vol 83. issue 3. 2010-06-02. PMID:20064585. |
serotonin, a key regulator of emotional behavior, is synthesized by tryptophan hydroxylase (tph). |
2010-06-02 |
2023-08-12 |
human |
| Hana Kuzelova, Radek Ptacek, Milan Mace. The serotonin transporter gene (5-HTT) variant and psychiatric disorders: review of current literature. Neuro endocrinology letters. vol 31. issue 1. 2010-05-13. PMID:20150867. |
this repeat length variant in the promoter region of this gene has been shown to affect the rate of serotonin uptake and may play a role in post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma. |
2010-05-13 |
2023-08-12 |
Not clear |
| Daniela Popa, Julie Cerdan, Christelle Repérant, Bruno P Guiard, Jean-Philippe Guilloux, Denis J David, Alain M Gardie. A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. European journal of pharmacology. vol 628. issue 1-3. 2010-04-05. PMID:19944680. |
a longitudinal study of 5-ht outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. |
2010-04-05 |
2023-08-12 |
mouse |
| Liviu G Crişan, Simona Pana, Romana Vulturar, Renata M Heilman, Raluca Szekely, Bogdan Druğa, Nicolae Dragoş, Andrei C Mi. Genetic contributions of the serotonin transporter to social learning of fear and economic decision making. Social cognitive and affective neuroscience. vol 4. issue 4. 2010-03-03. PMID:19535614. |
serotonin (5-ht) modulates emotional and cognitive functions such as fear conditioning (fc) and decision making. |
2010-03-03 |
2023-08-12 |
human |
| Parastoo Hashemi, Elyse C Dankoski, Jelena Petrovic, Richard B Keithley, R M Wightma. Voltammetric detection of 5-hydroxytryptamine release in the rat brain. Analytical chemistry. vol 81. issue 22. 2010-02-22. PMID:19827792. |
5-hydroxytryptamine (5-ht) is an important molecule in the brain that is implicated in mood and emotional processes. |
2010-02-22 |
2023-08-12 |
rat |
| Elin Elvander-Tottie, Therese M Eriksson, Johan Sandin, Sven Ove Ogre. 5-HT(1A) and NMDA receptors interact in the rat medial septum and modulate hippocampal-dependent spatial learning. Hippocampus. vol 19. issue 12. 2010-01-28. PMID:19309036. |
in conclusion, septal 5-ht(1a) receptors appears to play a more prominent role in emotional than in spatial memory. |
2010-01-28 |
2023-08-12 |
rat |
| Peter Zimmermann, Cornelia Mohr, Gottfried Spangle. Genetic and attachment influences on adolescents' regulation of autonomy and aggressiveness. Journal of child psychology and psychiatry, and allied disciplines. vol 50. issue 11. 2010-01-12. PMID:19769585. |
inter-individual differences in emotionality and emotion regulation have been shown to be influenced or moderated by molecular genetic differences in the serotonin transporter gene (5-htt) and by attachment patterns. |
2010-01-12 |
2023-08-12 |
Not clear |