| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Judith R Homber. Serotonin and decision making processes. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:21693132. |
based on 5-ht's evolutionary role, i hypothesize that 5-ht integrates expected, or changes in, relevant sensory and emotional internal/external information, leading to vigilance behaviour affecting various decision making processes. |
2012-04-19 |
2023-08-12 |
Not clear |
| Natalia Jaworska, Andrea Thompson, Dhrasti Shah, Derek Fisher, Vadim Ilivitsky, Verner Knot. Acute tryptophan depletion effects on the vertex and late positive potentials to emotional faces in individuals with a family history of depression. Neuropsychobiology. vol 65. issue 1. 2012-04-10. PMID:22094352. |
depression, which is associated with dysfunctional serotonin (5-ht) activity, may be characterized by impaired emotional information processing. |
2012-04-10 |
2023-08-12 |
Not clear |
| Kazuya Miyagawa, Minoru Tsuji, Kanji Fujimori, Yasuho Saito, Hiroshi Taked. Prenatal stress induces anxiety-like behavior together with the disruption of central serotonin neurons in mice. Neuroscience research. vol 70. issue 1. 2012-04-06. PMID:21320553. |
it has been widely accepted that central serotonin (5-hydroxytryptamine; 5-ht) neurons play a critical role in emotional behaviors. |
2012-04-06 |
2023-08-12 |
mouse |
| Michaela Defrancesco, Harald Niederstätter, Walther Parson, Herbert Oberacher, Hartmann Hinterhuber, Markus Canazei, Judith Bidner, Eberhard A Deisenhammer, Georg Kemmler, Elisabeth M Weiss, Josef Marksteine. Influence of serotonin transporter genotype and catechol-O-methyltransferase Val158Met polymorphism on recognition of emotional faces. Journal of the International Neuropsychological Society : JINS. vol 17. issue 6. 2012-03-12. PMID:22013977. |
in this study, we investigated how polymorphisms of the serotonin transporter (5-htt) and catechol-o-methyltransferase (comt) influence emotion recognition abilities. |
2012-03-12 |
2023-08-12 |
human |
| Mariano Soiza-Reilly, Kathryn G Common. Quantitative analysis of glutamatergic innervation of the mouse dorsal raphe nucleus using array tomography. The Journal of comparative neurology. vol 519. issue 18. 2012-03-08. PMID:21800318. |
serotonin (5-hydroxytryptamine, 5-ht) containing neurons located in the dorsal raphe nucleus (dr) comprise the main source of forebrain 5-ht and regulate emotional states in normal and pathological conditions including affective disorders. |
2012-03-08 |
2023-08-12 |
mouse |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
several lines of evidence indicate that psychostimulant withdrawal can induce negative emotional symptoms, such as anhedonia and dysphoria, which may be due in part, to dysfunction of the serotonin (5-ht) system, including alterations in 5-ht receptors. |
2012-03-07 |
2023-08-12 |
rat |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
these data indicate that region-specific changes in 5-ht(2a) receptor mrna expression occur in limbic system and associated areas following chronic d-amph treatment, supporting the notion that alterations in the 5-ht system may contribute to the negative emotional aspects of psychostimulant withdrawal. |
2012-03-07 |
2023-08-12 |
rat |
| Qing-fang Ge, Hui-yun Zhan. [Effects of Chinese herbal medicines for regulating liver qi on expression of 5-hydroxytryptamine 3B receptor in hypothalamic tissues of rats with anger emotion]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 9. issue 8. 2012-03-07. PMID:21849148. |
[effects of chinese herbal medicines for regulating liver qi on expression of 5-hydroxytryptamine 3b receptor in hypothalamic tissues of rats with anger emotion]. |
2012-03-07 |
2023-08-12 |
rat |
| Qing-fang Ge, Hui-yun Zhan. [Effects of Chinese herbal medicines for regulating liver qi on expression of 5-hydroxytryptamine 3B receptor in hypothalamic tissues of rats with anger emotion]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 9. issue 8. 2012-03-07. PMID:21849148. |
to explore the central mechanisms of anger emotion and the effects of chinese herbal medicines for regulating liver qi on the anger emotion and the expression level of 5-hydroxytryptamine 3b receptor (5-ht3br) in rat hypothalamus. |
2012-03-07 |
2023-08-12 |
rat |
| E S Deneri. Molecular genetics of mouse serotonin neurons across the lifespan. Neuroscience. vol 197. 2012-02-27. PMID:21920412. |
pet-1-based approaches have led to advances in understanding the role of 5-ht neurons in respiration, thermoregulation, emotional behaviors, maternal behavior, and the mechanism of antipsychotic drug actions. |
2012-02-27 |
2023-08-12 |
mouse |
| Raina D Pang, Zhuo Wang, Lauren P Klosinski, Yumei Guo, David H Herman, Tansu Celikel, Hong Wei Dong, Daniel P Holschneide. Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice. PloS one. vol 6. issue 8. 2012-02-24. PMID:21886833. |
we tested the hypothesis that male knockout mice show exaggerated limbic activation during exposure to an emotional stressor, similar to human subjects with genetically reduced transcription of the serotonin transporter. |
2012-02-24 |
2023-08-12 |
mouse |
| Eszter Székely, Catherine M Herba, Pascal P Arp, André G Uitterlinden, Vincent W V Jaddoe, Albert Hofman, Frank C Verhulst, James J Hudziak, Henning Tiemeie. Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study. Journal of child psychology and psychiatry, and allied disciplines. vol 52. issue 12. 2012-02-23. PMID:21864315. |
previous research highlights the significance of a functional polymorphism located in the promoter region (5-httlpr) of the serotonin transporter gene in emotional behaviour. |
2012-02-23 |
2023-08-12 |
Not clear |
| Ross A McDevitt, John F Neumaie. Regulation of dorsal raphe nucleus function by serotonin autoreceptors: a behavioral perspective. Journal of chemical neuroanatomy. vol 41. issue 4. 2012-02-22. PMID:21620956. |
this review provides an overview of 5-ht autoreceptors, focusing on their contribution in animal behavioral models of stress and emotion. |
2012-02-22 |
2023-08-12 |
Not clear |
| F F da Rocha, L Malloy-Diniz, N V Lage, H Corrê. The relationship between the Met allele of the BDNF Val66Met polymorphism and impairments in decision making under ambiguity in patients with obsessive-compulsive disorder. Genes, brain, and behavior. vol 10. issue 5. 2012-02-13. PMID:21401876. |
brain-derived neurotrophic factor (bdnf) gene has an important link to neurotransmitter systems, including serotonin, and seems to play a major role in emotional decision making. |
2012-02-13 |
2023-08-12 |
Not clear |
| Darakhshan J Halee. Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats. Pharmacological reports : PR. vol 63. issue 4. 2012-02-10. PMID:22001976. |
serotonin (5-hydroxytryptamine, 5-ht), acting via the hippocampus, is thought to be critical for the neuroadaptation that alleviates the adverse effects of stress on emotion and behavior. |
2012-02-10 |
2023-08-12 |
rat |
| Paulina Rok-Bujko, Paweł Krząścik, Janusz Szyndler, Wojciech Kostowski, Roman Stefańsk. The influence of neonatal serotonin depletion on emotional and exploratory behaviours in rats. Behavioural brain research. vol 226. issue 1. 2012-02-09. PMID:21893103. |
the influence of neonatal serotonin depletion on emotional and exploratory behaviours in rats. |
2012-02-09 |
2023-08-12 |
rat |
| Paulina Rok-Bujko, Paweł Krząścik, Janusz Szyndler, Wojciech Kostowski, Roman Stefańsk. The influence of neonatal serotonin depletion on emotional and exploratory behaviours in rats. Behavioural brain research. vol 226. issue 1. 2012-02-09. PMID:21893103. |
the aim of the present study was to examine the influence of neonatal 5-ht depletion on emotional and exploratory behaviours in adult rats. |
2012-02-09 |
2023-08-12 |
rat |
| Catherine J Harmer, Christian de Bodinat, Gerard R Dawson, Colin T Dourish, Lara Waldenmaier, Sally Adams, Philip J Cowen, Guy M Goodwi. Agomelatine facilitates positive versus negative affective processing in healthy volunteer models. Journal of psychopharmacology (Oxford, England). vol 25. issue 9. 2012-02-08. PMID:20660010. |
consequently, the current experimental study assessed the effect of agomelatine on emotional processing in healthy volunteers using an emotional test battery shown to be sensitive to serotonin and noradrenaline reuptake inhibitors. |
2012-02-08 |
2023-08-12 |
human |
| Boris B Gorzalka, Matthew N Hil. Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 7. 2012-02-08. PMID:21111017. |
specifically, a deficiency in endocannabinoid signaling is sufficient to produce a "depressive-like" phenotype at the preclinical level (including changes in rewarding, emotional and cognitive behavior and biological changes such as increased hpa axis activity, impaired stress adaptation, reduced neurogenesis and altered serotonin negative feedback), and capable of inducing symptoms of depression in humans at a clinical level. |
2012-02-08 |
2023-08-12 |
Not clear |
| Marielle Hess, Georg Höfner, Klaus T Wanne. (S)- and (R)-fluoxetine as native markers in mass spectrometry (MS) binding assays addressing the serotonin transporter. ChemMedChem. vol 6. issue 10. 2012-01-26. PMID:21793219. |
a recently established and validated lc-esi-ms/ms method for quantification of fluoxetine was used to implement ms binding assays for the human serotonin transporter (hsert)-the primary target in the treatment of depression and emotional disorders. |
2012-01-26 |
2023-08-12 |
human |