| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Rob Markus, Rudi De Raed. Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 4. 2011-12-12. PMID:21150915. |
although attentional bias for emotional information has been reliably observed in depression, the interaction between 5-ht transporter-linked promoter region (5-httlpr), brain 5-ht vulnerability, and acute stress on affective information processing has not yet been investigated. |
2011-12-12 |
2023-08-12 |
human |
| C Rob Markus, Rudi De Raed. Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 4. 2011-12-12. PMID:21150915. |
this study examines the effects of tryptophan (trp) augmentation (indicating 5-ht manipulation) on inhibition of negative emotional information under stress in mainly female s'/s'- vs l'/l'-allele carriers. |
2011-12-12 |
2023-08-12 |
human |
| Venu Narayanan, Rebecca S Heiming, Friederike Jansen, Jörg Lesting, Norbert Sachser, Hans-Christian Pape, Thomas Seidenbeche. Social defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice. PloS one. vol 6. issue 7. 2011-12-06. PMID:21818344. |
in this context, the 5-htt plays a key role in the regulation of central 5-ht neurotransmission, which is critically involved in the physiological regulation of emotions including fear and anxiety. |
2011-12-06 |
2023-08-12 |
mouse |
| F Gao, Y S Zhu, S G Wei, S B Li, J H La. Polymorphism G861C of 5-HT receptor subtype 1B is associated with heroin dependence in Han Chinese. Biochemical and biophysical research communications. vol 412. issue 3. 2011-11-21. PMID:21839728. |
the serotoninergic (5-ht) system regulates neuronal activity in broad brain regions, and appears to be particularly important for modulating behavioral and physiological functions such as mood, emotion, sleep and appetite. |
2011-11-21 |
2023-08-12 |
human |
| Nicolas Salomé, Magdalena Taube, Emil Egecioglu, Caroline Hansson, Björn Stenström, Duan Chen, Daniel R Andersson, H Georg Kuhn, Claes Ohlsson, Suzanne L Dickso. Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. The European journal of neuroscience. vol 33. issue 9. 2011-09-16. PMID:21535247. |
thus, gsx induces an alteration of emotional reactivity and a memory/cognitive deficit that is associated with reduced turnover of serotonin and dopamine in the nucleus accumbens and decreased expression of egr-1 in the hippocampus and amygdala. |
2011-09-16 |
2023-08-12 |
rat |
| Gabor Varga, Anna Szekely, Maria Sasvari-Szekel. Candidate gene studies of dopaminergic and serotonergic polymorphisms. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 13. issue 2. 2011-09-16. PMID:21677323. |
the most researched candidate genes of psychiatric genetic association studies are the components of the monoamine neurotransmitter systems, out of which serotonin and dopamine transmitter systems gained particular attention due to their major role in regulating emotional functions and cognitive processes. |
2011-09-16 |
2023-08-12 |
Not clear |
| Ping Zhong, Zhen Ya. Differential regulation of the excitability of prefrontal cortical fast-spiking interneurons and pyramidal neurons by serotonin and fluoxetine. PloS one. vol 6. issue 2. 2011-09-01. PMID:21383986. |
in this study, we investigated the effects of serotonin on different neuronal populations in prefrontal cortex (pfc), a major area controlling emotion and cognition. |
2011-09-01 |
2023-08-12 |
rat |
| Harumasa Takano, Hiroshi Ito, Hidehiko Takahashi, Ryosuke Arakawa, Masaki Okumura, Fumitoshi Kodaka, Tatsui Otsuka, Motoichiro Kato, Tetsuya Suhar. Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [¹¹C]dasb and [¹¹C]WAY100635 in young healthy men. Synapse (New York, N.Y.). vol 65. issue 7. 2011-08-16. PMID:21484882. |
the central serotonergic (5-ht) system is closely involved in regulating various mental functions such as mood and emotion. |
2011-08-16 |
2023-08-12 |
human |
| Ross A McDevitt, Ryoko Hiroi, Scott M Mackenzie, Nicholas C Robin, Aaron Cohn, Jeansok J Kim, John F Neumaie. Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior. Biological psychiatry. vol 69. issue 8. 2011-08-08. PMID:21353664. |
expression of 5-ht(1b) in the drn inversely correlates with behavioral measures of emotion, and viral-mediated overexpression of 5-ht(1b) receptors in the middle drn inversely reduces measures of fear and anxiety in unstressed rats. |
2011-08-08 |
2023-08-12 |
rat |
| Ann Pakalnis, Mark Splaingard, Deborah Splaingard, Donna Kring, Andrew Colvi. Serotonin effects on sleep and emotional disorders in adolescent migraine. Headache. vol 49. issue 10. 2011-08-04. PMID:19486363. |
serotonin effects on sleep and emotional disorders in adolescent migraine. |
2011-08-04 |
2023-08-12 |
Not clear |
| Elisabeth A H von dem Hagen, Luca Passamonti, Sarah Nutland, Jennifer Sambrook, Andrew J Calde. The serotonin transporter gene polymorphism and the effect of baseline on amygdala response to emotional faces. Neuropsychologia. vol 49. issue 4. 2011-07-26. PMID:21167188. |
previous research has found that a common polymorphism in the serotonin transporter gene (5-httlpr) is an important mediator of individual differences in brain responses associated with emotional behaviour. |
2011-07-26 |
2023-08-12 |
human |
| Ian M Anderson, Gabriella Juhasz, Emma Thomas, Darragh Downey, Shane McKie, J F William Deakin, Rebecca Elliot. The effect of acute citalopram on face emotion processing in remitted depression: a pharmacoMRI study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 1. 2011-07-20. PMID:20599362. |
both reduced serotonergic (5-ht) function and negative emotional biases have been associated with vulnerability to depression. |
2011-07-20 |
2023-08-12 |
human |
| Yasuhiro Katoh, Shinya Uchida, Masayoshi Kawai, Noriyoshi Takei, Norio Mori, Junichi Kawakami, Yoshiyuki Kagawa, Shizuo Yamada, Noriyuki Namiki, Hisakuni Hashimot. Onset of clinical effects and plasma concentration of fluvoxamine in Japanese patients. Biological & pharmaceutical bulletin. vol 33. issue 12. 2011-07-19. PMID:21139240. |
it is widely accepted that selective serotonin reuptake inhibitors (ssris) require 2 to 4 weeks of administration before improvements in emotional symptoms of depression are seen. |
2011-07-19 |
2023-08-12 |
Not clear |
| Randy A Sansone, Lori A Sanson. SSRI-Induced Indifference. Psychiatry (Edgmont (Pa. : Township)). vol 7. issue 10. 2011-07-14. PMID:21103140. |
in the existing literature, selective serotonin reuptake inhibitor exposure has been occasionally associated with both behavioral apathy and emotional blunting. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shreela Palit, Robert J Sheaff, Christopher R France, Sarah T McGlone, William T Potter, Allan R Harkness, John L McNulty, Emily J Bartley, Rachel Hoffmann, Julie K Monda, Jamie L Rhud. Serotonin transporter gene (5-HTTLPR) polymorphisms are associated with emotional modulation of pain but not emotional modulation of spinal nociception. Biological psychology. vol 86. issue 3. 2011-07-01. PMID:21291949. |
serotonin transporter gene (5-httlpr) polymorphisms are associated with emotional modulation of pain but not emotional modulation of spinal nociception. |
2011-07-01 |
2023-08-12 |
human |
| Christopher G Beevers, C Nathan Marti, Han-Joo Lee, Deborah L Stote, Robert E Ferrell, Ahmad R Hariri, Michael J Telc. Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information. Journal of abnormal psychology. vol 120. issue 1. 2011-06-30. PMID:21319930. |
associations between serotonin transporter gene promoter region (5-httlpr) polymorphism and gaze bias for emotional information. |
2011-06-30 |
2023-08-12 |
Not clear |
| Christopher G Beevers, C Nathan Marti, Han-Joo Lee, Deborah L Stote, Robert E Ferrell, Ahmad R Hariri, Michael J Telc. Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information. Journal of abnormal psychology. vol 120. issue 1. 2011-06-30. PMID:21319930. |
the serotonin transporter promoter region polymorphism (5-httlpr) is associated with neural response to negative images in brain regions involved in the experience of emotion. |
2011-06-30 |
2023-08-12 |
Not clear |
| Jonas Waider, Naozumi Araragi, Lise Gutknecht, Klaus-Peter Lesc. Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: a perspective. Psychoneuroendocrinology. vol 36. issue 3. 2011-06-21. PMID:21257271. |
based on genetic variation, there is accumulating evidence that altered function of tryptophan hydroxylase-2 (tph2), the enzyme critical for synthesis of serotonin (5-ht) in the brain, plays a role in anxiety-, aggression- and depression-related personality traits and in the pathogenesis of disorders featuring deficits in cognitive control and emotion regulation. |
2011-06-21 |
2023-08-12 |
mouse |
| Ai Koizumi, Norimichi Kitagawa, Miho S Kitamura, Hirohito M Kondo, Takao Sato, Makio Kashin. Serotonin transporter gene and inhibition of conflicting emotional information. Neuroreport. vol 21. issue 6. 2011-05-31. PMID:20216333. |
serotonin transporter gene and inhibition of conflicting emotional information. |
2011-05-31 |
2023-08-12 |
Not clear |
| Jennifer A Minnix, Jason D Robinson, Cho Y Lam, Brian L Carter, Jennifer E Foreman, David J Vandenbergh, Gail E Tomlinson, David W Wetter, Paul M Cinciripin. The serotonin transporter gene and startle response during nicotine deprivation. Biological psychology. vol 86. issue 1. 2011-04-20. PMID:20888887. |
affective startle probe methodology was used to examine the effects of nicotine administration and deprivation on emotional processes among individuals carrying at least one s allele versus those with the l/l genotype of the 5-hydroxytryptamine (serotonin) transporter linked polymorphic region, 5-httlpr in the promoter region of the serotonin transporter gene [solute ligand carrier family 6 member a4 (slc6a4) or sert]. |
2011-04-20 |
2023-08-12 |
human |