Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mei-See Man, Yevheniia Mikheenko, Katrin Braesicke, Gemma Cockcroft, Angela C Robert. Serotonin at the level of the amygdala and orbitofrontal cortex modulates distinct aspects of positive emotion in primates. The international journal of neuropsychopharmacology. vol 15. issue 1. 2015-01-22. PMID:21726490. |
this study investigated the role of 5-ht within the amygdala and the orbitofrontal cortex (ofc), on the expression of appetitive pavlovian conditioned emotional responses and their reversal in a primate, the common marmoset. |
2015-01-22 |
2023-08-12 |
marmoset |
Mei-See Man, Yevheniia Mikheenko, Katrin Braesicke, Gemma Cockcroft, Angela C Robert. Serotonin at the level of the amygdala and orbitofrontal cortex modulates distinct aspects of positive emotion in primates. The international journal of neuropsychopharmacology. vol 15. issue 1. 2015-01-22. PMID:21726490. |
similar infusions into the ofc, producing marked reductions in post-mortem 5-ht tissue levels, had no overall effect on autonomic or behavioural responses, either at retention or during reversal learning, but caused an uncoupling of these responses, thereby fractionating emotional output. |
2015-01-22 |
2023-08-12 |
marmoset |
Mei-See Man, Yevheniia Mikheenko, Katrin Braesicke, Gemma Cockcroft, Angela C Robert. Serotonin at the level of the amygdala and orbitofrontal cortex modulates distinct aspects of positive emotion in primates. The international journal of neuropsychopharmacology. vol 15. issue 1. 2015-01-22. PMID:21726490. |
these data demonstrate the critical role of the amygdala in the expression of appetitive autonomic conditioning, and the region-selective contribution of 5-ht in the amygdala and ofc, respectively, to the expression of conditioned behaviour and the overall coordination of the emotional response. |
2015-01-22 |
2023-08-12 |
marmoset |
Kwokming James Chen. Neurobiological mechanisms of acupuncture for some common illnesses: a clinician's perspective. Journal of acupuncture and meridian studies. vol 7. issue 3. 2015-01-13. PMID:24929454. |
acupuncture may also change the levels of neurotransmitters such as serotonin and dopamine, thereby affecting the emotional state and craving. |
2015-01-13 |
2023-08-13 |
Not clear |
Aimée E M Capello, C Rob Marku. Effect of sub chronic tryptophan supplementation on stress-induced cortisol and appetite in subjects differing in 5-HTTLPR genotype and trait neuroticism. Psychoneuroendocrinology. vol 45. 2015-01-12. PMID:24845181. |
brain 5-ht function can be manipulated by dietary administration of its amino acid precursor tryptophan (trp), and the beneficial effects of dietary trp on stress experience and emotional eating may be greatest following repeated administration in both stress- and 5-ht-vulnerable subjects. |
2015-01-12 |
2023-08-13 |
human |
Q Yu, C M Teixeira, D Mahadevia, Y Huang, D Balsam, J J Mann, J A Gingrich, M S Ansorg. Dopamine and serotonin signaling during two sensitive developmental periods differentially impact adult aggressive and affective behaviors in mice. Molecular psychiatry. vol 19. issue 6. 2015-01-09. PMID:24589889. |
it therefore appears that genetic and pharmacologic factors impacting dopamine and serotonin signaling during sensitive developmental periods can modulate adult monoaminergic function and thereby alter risk for aggressive and emotional dysfunction. |
2015-01-09 |
2023-08-12 |
mouse |
Jennifer A Sumner, Suzanne Vrshek-Schallhorn, Susan Mineka, Richard E Zinbarg, Michelle G Craske, Eva E Redei, Kate Wolitzky-Taylor, Emma K Ada. Effects of the serotonin transporter polymorphism and history of major depression on overgeneral autobiographical memory. Cognition & emotion. vol 28. issue 5. 2015-01-05. PMID:24341893. |
we investigated whether a polymorphism in the promoter region of the serotonin transporter gene (5-httlpr) was associated with ogm in interaction with a lifetime history of mdd in 370 young adults in a longitudinal study of risk for emotional disorders. |
2015-01-05 |
2023-08-12 |
Not clear |
A V Akhmadeev, L B Kalimullin. [Serotonine and sex steroids in the system of neuroendocrine regulation of amygdala functions]. Uspekhi fiziologicheskikh nauk. vol 44. issue 4. 2014-12-31. PMID:25438560. |
systematizes the data on the role of serotonin and sex steroids in the mechanisms involved in the stress response of amygdala, and its participation in the formation of mood, emotions and the genesis of depression. |
2014-12-31 |
2023-08-13 |
Not clear |
Jonas Waider, Florian Proft, Georg Langlhofer, Esther Asan, Klaus-Peter Lesch, Lise Gutknech. GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice. Histochemistry and cell biology. vol 139. issue 2. 2014-12-17. PMID:23052836. |
the changes likely reflect a combination of developmental alterations and functional adaptations of emotion circuits to balance the lack of 5-ht, and may underlie altered emotional behavior in 5-ht-deficient mice. |
2014-12-17 |
2023-08-12 |
mouse |
Ji S Lee, Hyun S Le. Reciprocal connections between CART-immunoreactive, hypothalamic paraventricular neurons and serotonergic dorsal raphe cells in the rat: Light microscopic study. Brain research. vol 1560. 2014-12-15. PMID:24642272. |
the present observation provided an anatomical basis for accumulating evidence in the literature that suggests a functional interaction between the cart and serotonin systems during the regulation of energy balance, emotional behavior, and arousal. |
2014-12-15 |
2023-08-12 |
rat |
Theodore A Slotkin, Jennifer Card, Frederic J Seidle. Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: sex-selective effects on cerebrocortical serotonergic function. Brain research bulletin. vol 102. 2014-12-03. PMID:24487013. |
we gave nicotine to adolescent rats (postnatal days pn30-47), simulating plasma levels in smokers, and then examined the subsequent effects of nicotine given again in adulthood (pn90-107), focusing on cerebrocortical serotonin levels and utilization (turnover) as an index of presynaptic activity of circuits involved in emotional state. |
2014-12-03 |
2023-08-12 |
rat |
Julian Macovean. Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies. Brain research. vol 1556. 2014-11-06. PMID:24508910. |
the new findings may have implications in understanding psychiatric disorders such as major depression which is characterized by abnormal serotonergic function and reward-related processing and may also provide a neural correlated for the emotional blunting observed in the clinical treatment of psychiatric disorders with selective serotonin reuptake inhibitors. |
2014-11-06 |
2023-08-12 |
human |
Benjamin D Sachs, Jason R Ni, Marc G Caro. Sex differences in response to chronic mild stress and congenital serotonin deficiency. Psychoneuroendocrinology. vol 40. 2014-10-09. PMID:24485484. |
overall, these results highlight the importance of interactions between psychiatric disease risk factors such as sex, chronic stress and congenital 5-ht deficiency in the development of aberrant emotional behavior. |
2014-10-09 |
2023-08-12 |
mouse |
Hsiang Yu Huang, I Hui Lee, Kao Chin Chen, Shih-Hsien Lin, Tzung Lieh Yeh, Po See Chen, Nan-Tsing Chiu, We Jen Yao, Chia-Chieh Chen, Mei-Hsiu Liao, Yen Kuang Yan. Serotonin transporter availability in the midbrain and perceived social support in healthy volunteers. Journal of psychosomatic research. vol 75. issue 6. 2014-10-07. PMID:24290049. |
serotonin modulates human behavior and emotion. |
2014-10-07 |
2023-08-12 |
human |
Bernardo Nardi, Alessandra Marini, Chiara Turchi, Emidio Arimatea, Adriano Tagliabracci, Cesario Bellantuon. Role of 5-HTTLPR polymorphism in the development of the inward/outward personality organization: a genetic association study. PloS one. vol 8. issue 12. 2014-09-30. PMID:24358153. |
the presence of different, consistent clinical patterns in inward and outward subjects is paralleled by differences in cerebral activation during emotional tasks on fmri and by different expression of some polymorphisms in serotonin pathways. |
2014-09-30 |
2023-08-12 |
human |
Antonella Gasbarri, Assunta Pompil. Serotonergic 5-HT7 receptors and cognition. Reviews in the neurosciences. vol 25. issue 3. 2014-09-25. PMID:24486730. |
the abundant distribution of serotonin (5-ht) in different areas of the central nervous system can explain the involvement of this neurotransmitter in the regulation of several functions, such as sleep, pain, feeding, and sexual and emotional behaviors. |
2014-09-25 |
2023-08-12 |
Not clear |
Weihai Chen, Qi Zhang, Wenxin Su, Haorong Zhang, Yu Yang, Jing Qiao, Nan Sui, Ming L. Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats. Pharmacology, biochemistry, and behavior. vol 117. 2014-09-25. PMID:24321440. |
given the known roles of serotonin (5-ht) in emotion, motivation, social behavior, and major depression - and its known interaction with dopamine - it is likely that serotonin also plays a crucial role in this behavior. |
2014-09-25 |
2023-08-12 |
rat |
Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
a vast number of imaging studies have demonstrated the impact of serotonin (5-ht) and brain-derived neurotrophic factor (bdnf) on emotion and memory-related networks in the context of major depressive disorder (mdd). |
2014-09-19 |
2023-08-12 |
human |
Jing Zhang, Andrea Jaquins-Gerstl, Kathryn M Nesbitt, Sarah C Rutan, Adrian C Michael, Stephen G Webe. In vivo monitoring of serotonin in the striatum of freely moving rats with one minute temporal resolution by online microdialysis-capillary high-performance liquid chromatography at elevated temperature and pressure. Analytical chemistry. vol 85. issue 20. 2014-08-19. PMID:24020786. |
this system is simple, efficient, reliable, and suitable for the study of serotonin neurochemistry associated with emotion and behavior. |
2014-08-19 |
2023-08-12 |
rat |
Sabrina Boll, Matthias Game. 5-HTTLPR modulates the recognition accuracy and exploration of emotional facial expressions. Frontiers in behavioral neuroscience. vol 8. 2014-08-07. PMID:25100964. |
individual genetic differences in the serotonin transporter-linked polymorphic region (5-httlpr) have been associated with variations in the sensitivity to social and emotional cues as well as altered amygdala reactivity to facial expressions of emotion. |
2014-08-07 |
2023-08-13 |
human |