| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ti-Fei Yuan, Nuno Barbosa Ferreira Rocha, Flávia Paes, Oscar Arias-Carrión, Sergio Machado, Alberto Souza de Sá Filh. Neural Mechanisms of Exercise: Effects on Gut Miccrobiota and Depression. CNS & neurological disorders drug targets. vol 14. issue 10. 2016-09-26. PMID:26556075. |
gut microbiota could as well contribute to the beneficial effects of exercise on cognition and emotion, either directly through serotonin signaling or indirectly by modulating metabolism and exercise performance. |
2016-09-26 |
2023-08-13 |
human |
| Emma Komulainen, Roope Heikkilä, Katarina Meskanen, Tuukka T Raij, Lauri Nummenmaa, Jari Lahti, Pekka Jylhä, Tarja Melartin, Catherine J Harmer, Erkki Isometsä, Jesper Ekelun. A single dose of mirtazapine attenuates neural responses to self-referential processing. Journal of psychopharmacology (Oxford, England). vol 30. issue 1. 2016-09-26. PMID:26577062. |
mirtazapine, an antidepressant that increases serotonin and norepinephrine release, enhances processing of positive and attenuates processing of negative emotional information in healthy volunteers after a single dose. |
2016-09-26 |
2023-08-13 |
human |
| Irene Gracia-Rubio, Maria Moscoso-Castro, Oscar J Pozo, Josep Marcos, Roser Nadal, Olga Valverd. Maternal separation induces neuroinflammation and long-lasting emotional alterations in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 65. 2016-09-14. PMID:26382758. |
emotional alterations like depression result in reduced serotonin availability and enhanced kynurenine metabolism through the action of indoleamine 2, 3-dioxygenase in response to neuroinflammatory factors. |
2016-09-14 |
2023-08-13 |
mouse |
| Tiago Souza Dos Santos, Jéssica Krüger, Fernando Falkenburger Melleu, Christina Herold, Karl Zilles, Anicleto Poli, Onur Güntürkün, José Marino-Net. Distribution of serotonin 5-HT1A-binding sites in the brainstem and the hypothalamus, and their roles in 5-HT-induced sleep and ingestive behaviors in rock pigeons (Columba livia). Behavioural brain research. vol 295. 2016-09-05. PMID:25843559. |
serotonin 1a receptors (5-ht1ars), which are widely distributed in the mammalian brain, participate in cognitive and emotional functions. |
2016-09-05 |
2023-08-13 |
pigeon |
| Alberto Montalbano, Jonas Waider, Mario Barbieri, Ozan Baytas, Klaus-Peter Lesch, Renato Corradetti, Boris Mlina. Cellular resilience: 5-HT neurons in Tph2(-/-) mice retain normal firing behavior despite the lack of brain 5-HT. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 11. 2016-08-26. PMID:26409296. |
considerable evidence links dysfunction of serotonin (5-hydroxytryptamine, 5-ht) transmission to neurodevelopmental and psychiatric disorders characterized by compromised "social" cognition and emotion regulation. |
2016-08-26 |
2023-08-13 |
mouse |
| Kaori Yamakawa, Masahiro Matsunaga, Tokiko Isowa, Hideki Ohir. Serotonin transporter gene polymorphism modulates inflammatory cytokine responses during acute stress. Scientific reports. vol 5. 2016-08-19. PMID:26349674. |
a short (s) variant, compared with a long (l) variant, of the promoter region of the 5htt gene-linked polymorphic region (5httlpr) has been related to emotional and stress hyper-reactivity. |
2016-08-19 |
2023-08-13 |
human |
| Jennifer S Yokoyama, Luke W Bonham, Virginia E Sturm, Babu Adhimoolam, Anna Karydas, Giovanni Coppola, Bruce L Miller, Katherine P Ranki. The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia. NeuroImage. Clinical. vol 9. 2016-07-21. PMID:26509115. |
the 5-httlpr variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia. |
2016-07-21 |
2023-08-13 |
Not clear |
| Jennifer S Yokoyama, Luke W Bonham, Virginia E Sturm, Babu Adhimoolam, Anna Karydas, Giovanni Coppola, Bruce L Miller, Katherine P Ranki. The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia. NeuroImage. Clinical. vol 9. 2016-07-21. PMID:26509115. |
5-httlpr-s modifies the serotonergic systems that support emotion and behavioral regulation by reducing gene expression, which slows the reuptake of serotonin, and is associated with distinct morphological and functional effects. |
2016-07-21 |
2023-08-13 |
Not clear |
| C R Markus, W I Klöpping-Ketelaars, W Pasman, B Klarenbeek, H van den Ber. Dose-Dependent Effect of α-Lactalbumin in Combination with Two Different Doses of Glucose on the Plasma Trp/LNAA Ratio. Nutritional neuroscience. vol 3. issue 5. 2016-07-16. PMID:27414133. |
a deficient brain serotonin function has been demonstrated in psychiatric disorders and increases in brain serotonin ameliorate emotional and behavioural abnormalities found in depression. |
2016-07-16 |
2023-08-13 |
human |
| Sudhakar Selvaraj, Elias Mouchlianitis, Paul Faulkner, Federico Turkheimer, Philip J Cowen, Jonathan P Roiser, Oliver Howe. Presynaptic Serotoninergic Regulation of Emotional Processing: A Multimodal Brain Imaging Study. Biological psychiatry. vol 78. issue 8. 2016-06-09. PMID:24882568. |
the amygdala is a central node in the brain network that processes aversive emotions and is extensively innervated by dorsal raphe nucleus (drn) serotonin (5-hydroxytryptamine [5-ht]) neurons. |
2016-06-09 |
2023-08-13 |
Not clear |
| Anna Castañé, Lucila Kargieman, Pau Celada, Analía Bortolozzi, Francesc Artiga. 5-HT2A receptors are involved in cognitive but not antidepressant effects of fluoxetine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 8. 2016-05-06. PMID:25914158. |
here we examine the role of 5-ht2a receptors in the processing of emotional and cognitive signals evoked by increasing the 5-ht tone after acute blockade of the 5-ht transporter. |
2016-05-06 |
2023-08-13 |
mouse |
| Markus Wöhr, Marcel M van Gaalen, Rainer K W Schwartin. Affective communication in rodents: serotonin and its modulating role in ultrasonic vocalizations. Behavioural pharmacology. vol 26. issue 6. 2016-05-05. PMID:26221830. |
5-ht plays a prominent role in regulating various types of psychological processes and functions, including mood and emotion, particularly anxiety, but also in regulating social behavior. |
2016-05-05 |
2023-08-13 |
mouse |
| Klaus-Peter Lesc. When the serotonin transporter gene meets adversity: the contribution of animal models to understanding epigenetic mechanisms in affective disorders and resilience. Current topics in behavioral neurosciences. vol 7. 2016-04-23. PMID:21225411. |
for example, a remarkable number of studies reported an association of variation in the human serotonin (5-ht) transporter gene (slc6a4, 5-htt, sert) with emotional and cognitive traits as well as increased risk for depression in interaction with psychosocial adversity. |
2016-04-23 |
2023-08-12 |
mouse |
| Vincent Beliveau, Claus Svarer, Vibe G Frokjaer, Gitte M Knudsen, Douglas N Greve, Patrick M Fishe. Functional connectivity of the dorsal and median raphe nuclei at rest. NeuroImage. vol 116. 2016-04-08. PMID:25963733. |
our results provide evidence for a resting-state network related to dr and mr and comprising regions receiving serotonergic innervation and centrally involved in 5-ht related behaviors including emotion, cognition and reward processing. |
2016-04-08 |
2023-08-13 |
human |
| Y Liu, M A Kelly, T J Sexton, J F Neumaie. 5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner. Neuroscience. vol 298. 2016-03-21. PMID:25907441. |
located in the nerve terminals of serotonergic neurons, 5-ht1b autoreceptors are poised to modulate synaptic 5-ht levels with precise temporal and spatial control, and play an important role in various emotional behaviors. |
2016-03-21 |
2023-08-13 |
mouse |
| Gunnar Flik, Joost H A Folgering, Thomas I H F Cremers, Ben H C Westerink, Eliyahu Dremenco. Interaction Between Brain Histamine and Serotonin, Norepinephrine, and Dopamine Systems: In Vivo Microdialysis and Electrophysiology Study. Journal of molecular neuroscience : MN. vol 56. issue 2. 2016-03-14. PMID:25820671. |
brain monoamines (serotonin, norepinephrine, dopamine, and histamine) play an important role in emotions, cognition, and pathophysiology and treatment of mental disorders. |
2016-03-14 |
2023-08-13 |
rat |
| Roger M Lan. Antidepressant drug development: Focus on triple monoamine reuptake inhibition. Journal of psychopharmacology (Oxford, England). vol 29. issue 5. 2016-02-23. PMID:25315829. |
a tri should more effectively activate mesolimbic dopamine-related reward-networks, restore positive mood and reduce potent 5-ht reuptake blockade associated "hypodopaminergic" adverse effects of decreased libido, weight gain and "blunting" of emotions. |
2016-02-23 |
2023-08-13 |
Not clear |
| K Helmbold, M Zvyagintsev, B Dahmen, S Bubenzer-Busch, T J Gaber, M J Crockett, M Klasen, C L Sánchez, A Eisert, K Konrad, U Habel, B Herpertz-Dahlmann, F D Zep. Effects of serotonin depletion on punishment processing in the orbitofrontal and anterior cingulate cortices of healthy women. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25869157. |
the results indicate reduced neural sensitivity to punishment after short-term depletion of 5-ht in brain areas related to emotion regulation (subgenual acc) increasing with depletion magnitude and in brain areas related to appraisal and expression of emotions (mofc and dorsal acc), increasing with trait impulsivity. |
2016-02-16 |
2023-08-13 |
human |
| Andrée-Anne Bouvette-Turcot, Michael Pluess, Annie Bernier, Marie-Hélène Pennestri, Robert Levitan, Marla B Sokolowski, James L Kennedy, Klaus Minde, Meir Steiner, Irina Pokhvisneva, Michael J Meaney, Hélène Gaudrea. Effects of Genotype and Sleep on Temperament. Pediatrics. vol 136. issue 4. 2016-01-28. PMID:26371199. |
we investigated whether a polymorphism in the serotonin transporter gene, which is linked to emotional function, is a potential moderator of the influences of sleep duration on infant temperament using longitudinal data. |
2016-01-28 |
2023-08-13 |
Not clear |
| Ran Ye, Meagan A Quinlan, Hideki Iwamoto, Hsiao-Huei Wu, Noah H Green, Christopher S Jetter, Douglas G McMahon, Jeremy Veestra-VanderWeele, Pat Levitt, Randy D Blakel. Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters. Frontiers in synaptic neuroscience. vol 7. 2016-01-21. PMID:26793096. |
the neurotransmitter serotonin [5-hydroxytryptamine (5-ht)] modulates many key brain functions including those subserving sensation, emotion, reward, and cognition. |
2016-01-21 |
2023-08-13 |
mouse |