| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisa A Kilpatrick, Emeran A Mayer, Jennifer S Labus, Arpana Gupta, Toyohiro Hamaguchi, Tomoko Mizuno, Hazuki Komuro, Michiko Kano, Motoyori Kanazawa, Masashi Aoki, Shin Fukud. Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus. PloS one. vol 10. issue 4. 2016-01-13. PMID:25893242. |
the 5-hydroxytryptamine transporter gene-linked polymorphic region (5-httlpr) has been linked to increased stress responsiveness and negative emotional states. |
2016-01-13 |
2023-08-13 |
Not clear |
| Saroj Kumar Das, Kalpana Barhwal, Sunil Kumar Hota, Mahendra Kumar Thakur, Ravi Bihari Srivastav. Disrupting monotony during social isolation stress prevents early development of anxiety and depression like traits in male rats. BMC neuroscience. vol 16. 2016-01-12. PMID:25880744. |
serotonin was depleted by administering para-chlorophenylalanine (pcpa) to a separate ph group (phpcpa), phno group (phnopcpa) and shno group (shnopcpa) to determine the role of serotonin in mediating monotony induced emotional mal-adaptations. |
2016-01-12 |
2023-08-13 |
rat |
| M E Glover, P C Pugh, N L Jackson, J L Cohen, A D Fant, H Akil, S M Clinto. Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats. Neuroscience. vol 284. 2015-12-30. PMID:25451292. |
selective serotonin reuptake inhibitor (ssri) antidepressants are the mainstay treatment for the 10-20% of pregnant and postpartum women who suffer major depression, but the effects of ssris on their children's developing brain and later emotional health are poorly understood. |
2015-12-30 |
2023-08-13 |
rat |
| M J Herrmann, J Bogon, S Quester, A Cordes, P Stenneken, A Reif, A-C Ehli. Serotonin transporter polymorphism modulates neural correlates of real-life joint action. An investigation with functional near-infrared spectroscopy (fNIRS). Neuroscience. vol 292. 2015-12-16. PMID:25711941. |
a functional polymorphism (5-httlpr) within the serotonin transporter gene (sert) has been associated with personality dimensions such as neuroticism, with emotional reactivity to negative events, and with an increased risk of affective disorders. |
2015-12-16 |
2023-08-13 |
human |
| Lucero Rengifo Ramos, Duverney Gaviria Arias, Liliana Salazar Salazar, Juan Pablo Vélez, Stella Lozano Pard. [Polymorphism in the Serotonin Transporter Gene (SLC6A4) and Emotional Bipolar Disorder in Two Regional Mental Health Centers from the Eje Cafetero (Colombia)]. Revista colombiana de psiquiatria. vol 41. issue 1. 2015-11-24. PMID:26573471. |
[polymorphism in the serotonin transporter gene (slc6a4) and emotional bipolar disorder in two regional mental health centers from the eje cafetero (colombia)]. |
2015-11-24 |
2023-08-13 |
Not clear |
| Zhoumeng Lin, Celia A Dodd, Shuo Xiao, Saritha Krishna, Xiaoqin Ye, Nikolay M Filipo. Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring. Toxicological sciences : an official journal of the Society of Toxicology. vol 141. issue 1. 2015-10-23. PMID:24913803. |
these results suggest that perinatal dw exposure to atr targets the nigrostriatal da pathway in dams and, especially, juvenile offspring, alters dams' cognitive performance, induces sex-selective changes involving motor and emotional functions in juvenile offspring, and decreases cognitive ability of adult female offspring, with the latter possibly associated with altered perirhinal cortex serotonin homeostasis. |
2015-10-23 |
2023-08-13 |
mouse |
| E L Gibson, K Vargas, E Hogan, A Holmes, P J Rogers, J Wittwer, J Kloek, R Goralczyk, M H Mohajer. Effects of acute treatment with a tryptophan-rich protein hydrolysate on plasma amino acids, mood and emotional functioning in older women. Psychopharmacology. vol 231. issue 24. 2015-10-13. PMID:24858376. |
effective functioning of the neurotransmitter serotonin is important for optimal cognitive and emotional function. |
2015-10-13 |
2023-08-13 |
Not clear |
| Yasufumi Sakakibara, Yoshiyuki Kasahara, F Scott Hall, Klaus-Peter Lesch, Dennis L Murphy, George R Uhl, Ichiro Sor. Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice. Psychopharmacology. vol 231. issue 21. 2015-10-12. PMID:24728652. |
a promoter variant of the serotonin transporter (sert) gene is known to affect emotional and cognitive regulation. |
2015-10-12 |
2023-08-13 |
mouse |
| Michael Winkelma. Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca. Current drug abuse reviews. vol 7. issue 2. 2015-09-28. PMID:25563446. |
serotonin has been long recognized as central to the psychedelics' well-known phenomenological, physical, emotional and cognitive dynamics. |
2015-09-28 |
2023-08-13 |
human |
| Liang Hu, Qin Wang, Zhen Qin, Kaiqi Su, Liquan Huang, Ning Hu, Ping Wan. Detection of 5-hydroxytryptamine (5-HT) in vitro using a hippocampal neuronal network-based biosensor with extracellular potential analysis of neurons. Biosensors & bioelectronics. vol 66. 2015-08-28. PMID:25530536. |
5-hydroxytryptamine (5-ht) is an important neurotransmitter in regulating emotions and related behaviors in mammals. |
2015-08-28 |
2023-08-13 |
Not clear |
| A V Ahmadeev, L B Kalimullin. [Paleoamygdala as the Neuroendocrine Center of Regulation of Reproductive Processis]. Uspekhi fiziologicheskikh nauk. vol 46. issue 2. 2015-08-04. PMID:26155668. |
systematizes the data on the role of serotonin and sex steroids in the mechanisms involved in the stress response of amygdala, and its participation in the formation of mood, emotions and the genesis of depression. |
2015-08-04 |
2023-08-13 |
Not clear |
| Jessica M Sales, Jennifer L Brown, Andrea L Swartzendruber, Erica L Smearman, Gene H Brody, Ralph DiClement. Genetic sensitivity to emotional cues, racial discrimination and depressive symptoms among African-American adolescent females. Frontiers in psychology. vol 6. 2015-07-09. PMID:26157407. |
specifically, genetic variation within the linked promoter region of the serotonin transporter gene (5-httlpr) is related to heightened reactivity to emotional environmental cues. |
2015-07-09 |
2023-08-13 |
human |
| Kazuko Hayashi, Kazuko Nakao, Kae Nakamur. Appetitive and aversive information coding in the primate dorsal raphé nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 15. 2015-06-18. PMID:25878290. |
serotonin is known to play a key role in the regulation of emotional behavior. |
2015-06-18 |
2023-08-13 |
monkey |
| Pierre-Eric Lutz, Gulebru Ayranci, Paul Chu-Sin-Chung, Audrey Matifas, Pascale Koebel, Dominique Filliol, Katia Befort, Abdel-Mouttalib Ouagazzal, Brigitte L Kieffe. Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 11. 2015-06-15. PMID:24874714. |
altogether, our findings reveal crucial and distinct roles for all three opioid receptors in the development of emotional alterations that follow a history of heroin exposure and open the way towards understanding opioid system-mediated serotonin homeostasis in heroin abuse. |
2015-06-15 |
2023-08-13 |
mouse |
| Jill D Waring, Amit Etkin, Joachim F Hallmayer, Ruth O'Har. Connectivity underlying emotion conflict regulation in older adults with 5-HTTLPR short allele: a preliminary investigation. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 22. issue 9. 2015-04-22. PMID:24119861. |
the serotonin transporter polymorphism short (s) allele is associated with heightened emotional reactivity and reduced emotion regulation, which increases vulnerability to depression and anxiety disorders. |
2015-04-22 |
2023-08-12 |
Not clear |
| Joaquim Radua, Wissam El-Hage, Gemma C Monté, Benedicte Gohier, Maria Tropeano, Mary L Phillips, Simon A Surguladz. COMT Val158Met × SLC6A4 5-HTTLPR interaction impacts on gray matter volume of regions supporting emotion processing. Social cognitive and affective neuroscience. vol 9. issue 8. 2015-04-10. PMID:23748501. |
there have been several reports on the association between the val(158)met genetic polymorphism of the catechol-o-methyltransferase (comt) gene, as well as the serotonin transporter-linked polymorphic region (5-httlpr) of the serotonin transporter gene (slc6a4), and frontolimbic region volumes, which have been suggested to underlie individual differences in emotion processing or susceptibility to emotional disorders. |
2015-04-10 |
2023-08-12 |
human |
| Valentina Mosienko, Susann Matthes, Natalie Hirth, Daniel Beis, Michael Flinders, Michael Bader, Anita C Hansson, Natalia Alenin. Adaptive changes in serotonin metabolism preserve normal behavior in mice with reduced TPH2 activity. Neuropharmacology. vol 85. 2015-03-30. PMID:24863038. |
progressive reduction in tph2 activity had no effect on emotional behavior, and only slightly affected brain serotonin levels. |
2015-03-30 |
2023-08-13 |
mouse |
| Marcos Gonçalves de Rezende, Cybele Garcia-Leal, Frederico Guilherme Graeff, Cristina Marta Del-Be. The 5-HT1D/1B receptor agonist sumatriptan enhances fear of simulated speaking and reduces plasma levels of prolactin. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:23325368. |
because sumatriptan decreases 5-ht release into the extracellular space, the potentiation of spst-induced fear caused by the drug supports the hypothesis that 5-ht attenuates this emotional state. |
2015-01-27 |
2023-08-12 |
human |
| Marcos Gonçalves de Rezende, Cybele Garcia-Leal, Frederico Guilherme Graeff, Cristina Marta Del-Be. The 5-HT1D/1B receptor agonist sumatriptan enhances fear of simulated speaking and reduces plasma levels of prolactin. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:23325368. |
as acute administration of antidepressants has also been shown to enhance speaking fear and increase plasma prolactin, in contrast to sumatriptan, the 5-ht regulation of stress-hormone release is likely to be different from that of emotion. |
2015-01-27 |
2023-08-12 |
human |
| Scott J Moeller, Muhammad A Parvaz, Elena Shumay, Salina Wu, Nicasia Beebe-Wang, Anna B Konova, Michail Misyrlis, Nelly Alia-Klein, Rita Z Goldstei. Monoamine polygenic liability in health and cocaine dependence: imaging genetics study of aversive processing and associations with depression symptomatology. Drug and alcohol dependence. vol 140. 2015-01-23. PMID:24837582. |
gene polymorphisms that affect serotonin signaling modulate reactivity to salient stimuli and risk for emotional disturbances. |
2015-01-23 |
2023-08-13 |
Not clear |