| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Nagahama, R Dawson, S Opari. Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 180. issue 2. 1985-11-20. PMID:4048165. |
to elucidate the role of the central gamma-aminobutyric acid (gaba) system in the maintenance of deoxycorticosterone (doca)nacl hypertension, the responses of mean arterial pressure (map), plasma norepinephrine (ne), and epinephrine (ep) to intracerebroventricular (icv) administration of muscimol, a gaba agonist, and the responses of map to bicuculline, a gaba antagonist, and to clonidine, an alpha 2-adrenoceptor agonist known to lower blood pressure by inhibiting sympathetic tone, were examined in conscious, unrestrained 4 week doca/nacl hypertensive rats and age-matched uninephrectomized control rats. |
1985-11-20 |
2023-08-11 |
rat |
| S F Vatne. Regulation of coronary resistance vessels and large coronary arteries. The American journal of cardiology. vol 56. issue 9. 1985-10-28. PMID:2864851. |
stimulation of alpha 1- and alpha 2-adrenergic receptors with phenylephrine and b-ht 920, respectively, also increased calculated coronary vascular resistance in the conscious animal. |
1985-10-28 |
2023-08-11 |
Not clear |
| M Hiwatari, C I Johnsto. Importance of endogenous vasopressin in the hypertensive and bradycardic response to central alpha 1-adrenergic stimulation. Clinical and experimental pharmacology & physiology. vol 12. issue 3. 1985-10-15. PMID:2863022. |
administration of the alpha 1-agonists, methoxamine and phenylephrine, were examined in conscious long-evans (le) rats and brattleboro rats with hereditary hypothalamic diabetes insipidus (di). |
1985-10-15 |
2023-08-11 |
rat |
| P Falardeau, M Robillard, A Martinea. Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat. Prostaglandins. vol 29. issue 4. 1985-07-12. PMID:3890022. |
in order to do so, we monitored the urinary excretion of pgi2-m during paired intravenous infusions of 6-oxo-pgf1 alpha (the stable product of the spontaneous hydrolysis of pgi2) in conscious, unrestrained shr and wky rats aged 12-15 weeks, in doses ranging from 250 to 700 ng. |
1985-07-12 |
2023-08-11 |
rat |
| L Pichler, W Kobinge. Possible function of alpha 1-adrenoceptors in the CNS in anaesthetized and conscious animals. European journal of pharmacology. vol 107. issue 3. 1985-05-10. PMID:2984009. |
possible function of alpha 1-adrenoceptors in the cns in anaesthetized and conscious animals. |
1985-05-10 |
2023-08-11 |
mouse |
| C E Wright, J A Angu. Haemodynamic response to ketanserin in rabbits with Page hypertension: comparison with prazosin. Journal of hypertension. vol 1. issue 2. 1985-04-26. PMID:6681038. |
the role of alpha 1-adrenoceptors in the hypotensive response to ketanserin was studied in conscious normotensive (sham-operated) and page hypertensive (two-kidney, two wrapped) rabbits. |
1985-04-26 |
2023-08-12 |
Not clear |
| R W Lappe, B A Saslow, R L Wend. Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. Journal of cardiovascular pharmacology. vol 6 Suppl 5. 1985-03-13. PMID:6084118. |
effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. |
1985-03-13 |
2023-08-12 |
rat |
| M E Langha. The intraocular pressure and the pupillary responses of conscious rabbits to racemic erythro-alpha-methylnorepinephrine. Experimental eye research. vol 39. issue 6. 1985-03-05. PMID:6151514. |
the intraocular pressure and the pupillary responses in conscious rabbits to racemic erythro-alpha-methylnorepinephrine (alpha mene) have been investigated and its activity compared to l-norepinephrine (ne). |
1985-03-05 |
2023-08-12 |
Not clear |
| D W Harron, W Kobinger, C Lilli. Effects of peripheral alpha 1- and alpha 2-adrenoceptor agonists on baroreceptor responsiveness in conscious dogs. European journal of pharmacology. vol 104. issue 1-2. 1985-01-03. PMID:6149945. |
effects of peripheral alpha 1- and alpha 2-adrenoceptor agonists on baroreceptor responsiveness in conscious dogs. |
1985-01-03 |
2023-08-12 |
Not clear |
| S D Romero, D Chyatte, D E Byer, J C Romero, T L Yaks. Measurement of prostaglandins in the cerebrospinal fluid in cat, dog, and man. Journal of neurochemistry. vol 43. issue 6. 1984-12-20. PMID:6593432. |
although the prostaglandin profile for a given species remained constant (cat, pge2:6-keto-pgf1 alpha:txb2:pgf2 alpha; dog, txb2:pge2:6-keto-pgf1 alpha:pgf2 alpha), the absolute levels were found to be lower in the pentobarbital-anesthetized animals than in conscious cats. |
1984-12-20 |
2023-08-12 |
human |
| M Saeed, J Holtz, O Sommer, G Kühne, E Basseng. Beta-adrenergic activation of the renin-angiotensin system following alpha 2-, alpha 1-, or nonselective alpha-blockade in conscious dogs: no relation to the changes in blood pressure. Journal of cardiovascular pharmacology. vol 6. issue 4. 1984-09-24. PMID:6206326. |
beta-adrenergic activation of the renin-angiotensin system following alpha 2-, alpha 1-, or nonselective alpha-blockade in conscious dogs: no relation to the changes in blood pressure. |
1984-09-24 |
2023-08-12 |
Not clear |
| M Saeed, J Holtz, O Sommer, G Kühne, E Basseng. Beta-adrenergic activation of the renin-angiotensin system following alpha 2-, alpha 1-, or nonselective alpha-blockade in conscious dogs: no relation to the changes in blood pressure. Journal of cardiovascular pharmacology. vol 6. issue 4. 1984-09-24. PMID:6206326. |
in conscious dogs, alpha 2-blockade (0.3 mg/kg rauwolscine, n = 10) increased mean arterial pressure by 40 mm hg, while hypotension by 8 mm hg occurred following nonselective alpha-blockade (1.5 mg/kg phentolamine, n = 9) and by 20 mm hg following alpha 1-blockade (1.2 mg/kg prazosin, n = 10). |
1984-09-24 |
2023-08-12 |
Not clear |
| J A Hannah, C A Hamilton, J L Rei. An analysis of the pressor responses to putative alpha 1 and alpha 2-adrenoreceptor agonists given intravenously to conscious rabbits. Journal of autonomic pharmacology. vol 4. issue 2. 1984-09-19. PMID:6146624. |
an analysis of the pressor responses to putative alpha 1 and alpha 2-adrenoreceptor agonists given intravenously to conscious rabbits. |
1984-09-19 |
2023-08-12 |
rabbit |
| J A Hannah, C A Hamilton, J L Rei. An analysis of the pressor responses to putative alpha 1 and alpha 2-adrenoreceptor agonists given intravenously to conscious rabbits. Journal of autonomic pharmacology. vol 4. issue 2. 1984-09-19. PMID:6146624. |
the selectivity of a range of alpha 1 and alpha 2-adrenoreceptor agonists was examined in the conscious rabbit. |
1984-09-19 |
2023-08-12 |
rabbit |
| J A Hannah, C A Hamilton, J L Rei. Pretreatment with aspirin does not influence the pressor response to alpha 2-adrenoceptor agonists in conscious rabbits. The Journal of pharmacy and pharmacology. vol 36. issue 6. 1984-08-31. PMID:6146681. |
pretreatment with aspirin does not influence the pressor response to alpha 2-adrenoceptor agonists in conscious rabbits. |
1984-08-31 |
2023-08-12 |
Not clear |
| T FitzGibbon, J S Hayward, D Walke. EEG and visual evoked potentials of conscious man during moderate hypothermia. Electroencephalography and clinical neurophysiology. vol 58. issue 1. 1984-08-20. PMID:6203702. |
five conscious, normal humans were cooled by water immersion until their core temperatures were near 33.5 degrees c. when hypothermic at this level, small shifts of eeg frequencies to more theta and beta and less alpha activity occurred in comparison to normothermia. |
1984-08-20 |
2023-08-12 |
human |
| G R Heyndrickx, J P Vilaine, E J Moerman, I Leuse. Role of prejunctional alpha 2-adrenergic receptors in the regulation of myocardial performance during exercise in conscious dogs. Circulation research. vol 54. issue 6. 1984-08-07. PMID:6145527. |
role of prejunctional alpha 2-adrenergic receptors in the regulation of myocardial performance during exercise in conscious dogs. |
1984-08-07 |
2023-08-12 |
Not clear |
| G R Heyndrickx, J P Vilaine, E J Moerman, I Leuse. Role of prejunctional alpha 2-adrenergic receptors in the regulation of myocardial performance during exercise in conscious dogs. Circulation research. vol 54. issue 6. 1984-08-07. PMID:6145527. |
we examined, in conscious dogs, the potential role of prejunctional alpha 2-adrenergic receptors for the regulation of heart rate and contractility response to exercise through modulation of the neurotransmitter release. |
1984-08-07 |
2023-08-12 |
Not clear |
| G R Heyndrickx, J P Vilaine, E J Moerman, I Leuse. Role of prejunctional alpha 2-adrenergic receptors in the regulation of myocardial performance during exercise in conscious dogs. Circulation research. vol 54. issue 6. 1984-08-07. PMID:6145527. |
these observations indicate that, in the intact conscious animal, prejunctional alpha 2-adrenoreceptors are stimulated during exercise, thereby modulating the norepinephrine release through a negative feedback inhibitory mechanism. |
1984-08-07 |
2023-08-12 |
Not clear |
| S L Pfister, T K Keeto. Yohimbine induces sympathetically mediated renin release in the conscious rat. European journal of pharmacology. vol 97. issue 3-4. 1984-05-07. PMID:6323192. |
the preferential alpha 2-adrenergic antagonist yohimbine (4 mg/kg s.c.) caused a time-related increase in serum renin activity and heart rate in conscious sprague-dawley rats. |
1984-05-07 |
2023-08-12 |
rat |