| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S G Cella, G B Picotti, M Morgese, P Mantegazza, E E Mülle. Presynaptic alpha 2 -adrenergic stimulation leads to growth hormone release in the dog. Life sciences. vol 34. issue 5. 1984-03-21. PMID:6141513. |
in previous studies we have shown that the alpha 2 -adrenergic receptor agonist clonidine (clon) releases growth hormone (gh) in conscious dogs, an effect abolished by the selective alpha 2-receptor antagonist yohimbine (yoh) and by reserpine, but not by the alpha 1-receptor antagonist prazosin (1). |
1984-03-21 |
2023-08-12 |
dog |
| K Ishikawa, M Suzuki, T Kakegaw. Localization of alpha 2-adrenergic agonist sensitive area in the hypothalamus for growth hormone release in the rat. Endocrinologia japonica. vol 30. issue 3. 1984-03-06. PMID:6141046. |
to determine the localization of the clonidine sensitive area responsible for gh release, a minute amount of the alpha 2-agonist (67 ng/0.2 microliter) was injected into the hypothalamus and vicinity of adult male conscious rats. |
1984-03-06 |
2023-08-12 |
rat |
| J Puurune. Central nervous system effects of arachidonic acid, PGE2, PGF2 alpha, PGD2 and PGI2 on gastric secretion in the rat. British journal of pharmacology. vol 80. issue 2. 1984-02-14. PMID:6360279. |
the results indicate that pge2 and pgf2 alpha have a potent central antisecretory action in conscious, pylorus-ligated rats, whereas arachidonic acid, pgd2 and pgi2 do not have any central effects on gastric secretion. |
1984-02-14 |
2023-08-12 |
rat |
| O Khorram, L R DePalatis, S M McCan. The effect and possible mode of action of alpha-melanocyte-stimulating hormone on gonadotropin release in the ovariectomized rat: an in vivo and in vitro analysis. Endocrinology. vol 114. issue 1. 1984-02-14. PMID:6418525. |
injection of alpha msh into the third ventricle of the brain and sampling at 5, 10, 15, 30, and 60 min postinjection produced a significant lowering of plasma lh, but not of fsh, in conscious ovariectomized (ovx) rats. |
1984-02-14 |
2023-08-12 |
rat |
| W Schramm, L Bovaird, M E Glew, G Schramm, J A McCracke. Corpus luteum regression induced by ultra-low pulses of prostaglandin F2 alpha. Prostaglandins. vol 26. issue 3. 1984-02-14. PMID:6581508. |
to mimic physiological conditions, hour-long infusions of pgf2 alpha in increasing concentrations were given either 4 times in 19 h or 5 times in 25 h into the arterial supply of the autotransplanted ovary in conscious sheep on day 12 of an induced cycle. |
1984-02-14 |
2023-08-12 |
Not clear |
| K Hashimoto, T Shibuya, S Ima. Effects of prostaglandins on late coronary ligation arrhythmias in the dog. Japanese journal of pharmacology. vol 33. issue 5. 1984-01-27. PMID:6358586. |
effects of an intravenous injection of indomethacin, prostaglandins (pgs) e1, e2 and f2 alpha and prostacyclin were examined by the use of a model of two-stage coronary ligation arrhythmias in conscious dogs. |
1984-01-27 |
2023-08-12 |
dog |
| H Majewski, L Hedler, K Stark. Modulation of noradrenaline release in the conscious rabbit through alpha-adrenoceptors. European journal of pharmacology. vol 93. issue 3-4. 1984-01-07. PMID:6139286. |
the effects of selective alpha 1- and alpha 2-adrenoceptor antagonists and agonists on the noradrenaline release rate and plasma catecholamine levels were studied in the conscious rabbit. |
1984-01-07 |
2023-08-12 |
human |
| H Majewski, L Hedler, K Stark. Modulation of noradrenaline release in the conscious rabbit through alpha-adrenoceptors. European journal of pharmacology. vol 93. issue 3-4. 1984-01-07. PMID:6139286. |
the results are compatible with, but of course do not prove the hypothesis that in the conscious rabbit, noradrenaline release from sympathetic nerves is modulated through presynaptic alpha 2-adrenoceptors. |
1984-01-07 |
2023-08-12 |
human |
| C A Hamilton, J L Reid, D J Sumne. Acute effects of phenoxybenzamine on alpha-adrenoceptor responses in vivo and in vitro: relation of in vivo pressor responses to the number of specific adrenoceptor binding sites. Journal of cardiovascular pharmacology. vol 5. issue 5. 1983-12-20. PMID:6195478. |
pressor responses to intravenous phenylephrine, an adrenoceptor agonist, and to the alpha 2-adrenoceptor-selective agonist guanabenz were examined in conscious rabbits 30 min after treatment with a range of doses of phenoxybenzamine (10(-5) to 5 mg/kg). |
1983-12-20 |
2023-08-12 |
Not clear |
| A Auriac, J Azam, J C Dumas, G Roux, J L Montastru. [Role of alpha 1 adrenergic receptors in water balance in the rat]. Journal de pharmacologie. vol 14. issue 3. 1983-12-20. PMID:6314053. |
the effects of phenylephrine (alpha 1 +) and prazosin (alpha 1 -) on water intake, diuresis, food intake and blood pressure were compared in conscious normal and diabetic insipidus (di) long evans rats. |
1983-12-20 |
2023-08-12 |
rat |
| C Advenier, A Floch, B Mallar. Bronchopulmonary effects of clonidine on the bronchomotor responses of the guinea-pig. European journal of pharmacology. vol 89. issue 1-2. 1983-08-17. PMID:6861893. |
a specific involvement of alpha 2-adrenoceptors stimulated by clonidine with subsequent reduction of the adrenergic activity associated with bronchospasm could therefore be demonstrated in the conscious guinea-pig during bronchomotor reactions. |
1983-08-17 |
2023-08-12 |
Not clear |
| J A Hannah, C A Hamilton, J L Rei. RX781094, a new potent alpha 2 adrenoceptor antagonist. In vivo and in vitro studies in the rabbit. Naunyn-Schmiedeberg's archives of pharmacology. vol 322. issue 3. 1983-08-11. PMID:6135163. |
its effects on cardiovascular response "in vivo" before and after administration of alpha 1 and alpha 2 adrenoceptor agonists have been studied in conscious and anaesthetized rabbits. |
1983-08-11 |
2023-08-12 |
rabbit |
| P Christensen, K Gréen, P P Leyssa. The relationship between urinary prostaglandin excretion rates and urine flow in conscious rats. Evaluation of the radioimmunoassay by gas chromatography-mass spectrometry. Acta physiologica Scandinavica. vol 117. issue 1. 1983-07-15. PMID:6574691. |
in conscious rats prostaglandin e2- and f2 alpha excretion rates increased from about 20 to more than 100 pg/min/g kidney weight as urine flow decreased from about 10 to below 1 microliter/min/g kidney weight following 24 h of water deprivation confirming previous data from surgically prepared rats (leyssac & christensen 1981 b). |
1983-07-15 |
2023-08-12 |
rat |
| P Soding, J P Coghlan, D A Denton, W F Graham, T J Humphery, B A Scoggin. The effect of ACTH on the blood clearance rate of aldosterone, cortisol, 17 alpha-hydroxyprogesterone and 17 alpha, 20 alpha-dihydroxy-4-pregnen-3-one in the sheep. Journal of steroid biochemistry. vol 18. issue 2. 1983-06-10. PMID:6302397. |
the blood clearance rate (bcr) of aldosterone, cortisol, 17 alpha-hydroxyprogesterone (17 alpha ohp) and 17 alpha, 20 alpha-dihydroxy-4-pregnen-3-one (17 alpha 20 alpha ohp) has been measured in conscious sheep prior to and after 5 or 6 days acth treatment. |
1983-06-10 |
2023-08-12 |
Not clear |
| B G Zimmerman, R D Largen. Relationship of alpha receptor types to hypotension and renal vasodilation caused by alpha blockers in conscious dogs. Hypertension (Dallas, Tex. : 1979). vol 5. issue 2 Pt 2. 1983-04-21. PMID:6131031. |
relationship of alpha receptor types to hypotension and renal vasodilation caused by alpha blockers in conscious dogs. |
1983-04-21 |
2023-08-12 |
Not clear |
| L Proulx-Ferland, M Breault, J Cot. Alpha 1-adrenergic stimulation of ACTH secretion in vivo in the rat. Progress in neuro-psychopharmacology & biological psychiatry. vol 6. issue 4-6. 1983-04-07. PMID:6298888. |
while having no effect alone under basal conditions (conscious freely-moving animals), the highly specific alpha 1-adrenergic antagonist prazosin (0.25 micrograms) almost completely reverses the stimulatory effect of phenylephrine. |
1983-04-07 |
2023-08-12 |
rat |
| P J Beckett, L Finc. The alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat. European journal of pharmacology. vol 82. issue 3-4. 1982-12-21. PMID:6127223. |
the alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat. |
1982-12-21 |
2023-08-12 |
cat |
| P J Beckett, L Finc. The alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat. European journal of pharmacology. vol 82. issue 3-4. 1982-12-21. PMID:6127223. |
an attempt has been made to characterise the alpha-adrenoceptor subtype (alpha 1 or alpha 2) mediating the hypotensive and bradycardic action of clonidine in conscious renal hypertensive cats. |
1982-12-21 |
2023-08-12 |
cat |
| C A Hamilton, J L Rei. The effects of intravenous 6-hydroxydopamine on peripheral alpha-adrenoreceptors. Journal of autonomic pharmacology. vol 2. issue 1. 1982-09-10. PMID:6284763. |
5 in conscious animals 6-hydroxydopamine pretreatment causes alteration in responses mediated by postsynaptic alpha 1-but not postsynaptic alpha 2-adrenoreceptors. |
1982-09-10 |
2023-08-12 |
Not clear |
| P Macho, S F Vatne. Effects of prazosin on coronary and left ventricular dynamics in conscious dogs. Circulation. vol 65. issue 6. 1982-07-19. PMID:7074779. |
the left ventricular (lv) and coronary vascular effects of prazosin, a drug that reduces peripheral vascular resistance by blocking postsynaptic alpha receptors, were examined in conscious dogs. |
1982-07-19 |
2023-08-12 |
Not clear |