| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Whiteis, D D Lund, P G Schmi. Presynaptic regulation of cardiac sympathetic function in hypoxic guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985). vol 70. issue 6. 1991-10-08. PMID:1885451. |
to evaluate presynaptic regulation of kne, conscious guinea pigs subjected to normoxia and then hypoxia (n = 7-8 in each group) were pretreated with 1) vehicle; 2) a cholinergic muscarinic antagonist, methyl atropine; 3) an alpha 2-antagonist, yohimbine; or 4) a combination of the two. |
1991-10-08 |
2023-08-11 |
Not clear |
| E Colombari, W A Saad, L A Camargo, A Renzi, L A de-Luca Júnior, A C Ferrari, J V Menan. The effect of phentolamine on the pressor response to centrally administered clonidine in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 23. issue 8. 1991-09-05. PMID:2101098. |
in the present study we investigate the effect of the previous injection of phentolamine (a nonspecific alpha-adrenergic antagonist) into the lateral hypothalamus (lh) and lateral ventricle (lv) on the pressor and bradycardic responses produced by the injection of clonidine (an alpha 2-adrenergic agonist) into these same areas of conscious rats. |
1991-09-05 |
2023-08-11 |
rat |
| S Vonhof, A L Siré. Reversal of mu-opioid-mediated respiratory depression by alpha 2-adrenoceptor antagonism. Life sciences. vol 49. issue 2. 1991-08-02. PMID:1676481. |
the present study was performed in order to evaluate the effects of the selective alpha 2-adrenoceptor antagonist 6-chloro-2,3,4,5-tetrahydro-3-methyl-1h-3-benzazepine (sk&f 86466) on dermorphin-induced analgesia, respiratory depression and inhibition of locomotor activity in the conscious rat. |
1991-08-02 |
2023-08-11 |
rat |
| M J Ciancio, J Hunt, S B Jones, J P Filkin. Comparative and interactive in vivo effects of tumor necrosis factor alpha and endotoxin. Circulatory shock. vol 33. issue 2. 1991-07-22. PMID:2049814. |
a comparative and interactive analysis of the effects of tumor necrosis factor alpha (tnf) and endotoxin (etx) on selected hemodynamic and glucoregulatory alterations was performed in conscious, unrestrained, adult male holtzman rats. |
1991-07-22 |
2023-08-11 |
rat |
| S Oda, H Fujimura, Y Sasaki, A Ohned. Alpha 2-adrenergic modulation of glucagon and insulin secretions in sheep. The Tohoku journal of experimental medicine. vol 163. issue 2. 1991-07-18. PMID:1675498. |
to investigate the effects of alpha 2-adrenergic receptors on the secretions of pancreatic glucagon and insulin, clonidine, midaglizole and yohimbine were intravenously administered in four conscious sheep. |
1991-07-18 |
2023-08-11 |
Not clear |
| S Oda, H Fujimura, Y Sasaki, A Ohned. Alpha 2-adrenergic modulation of glucagon and insulin secretions in sheep. The Tohoku journal of experimental medicine. vol 163. issue 2. 1991-07-18. PMID:1675498. |
it is concluded that the glucagon secretion is enhanced and the insulin release is inhibited by alpha 2-adrenergic stimulation in conscious sheep. |
1991-07-18 |
2023-08-11 |
Not clear |
| J D Stone, J T Crofton, L Shar. Sex differences in central adrenoreceptor-mediated vasopressin response to hemorrhage. The American journal of physiology. vol 260. issue 5 Pt 1. 1991-06-24. PMID:1852113. |
hemorrhage-induced changes in the plasma vasopressin concentration and mean arterial blood pressure (mabp) were studied in conscious rats of both sexes with and without central alpha 1-adrenoreceptor blockade. |
1991-06-24 |
2023-08-11 |
rat |
| K D Beller, R Boer, K H Sanders, B Walte. Is blockade of alpha 1-adrenoceptors favourable in hypotension induced by stimulation of serotonin1A receptors in conscious dogs? Drugs. vol 40 Suppl 4. 1991-06-19. PMID:1982653. |
is blockade of alpha 1-adrenoceptors favourable in hypotension induced by stimulation of serotonin1a receptors in conscious dogs? |
1991-06-19 |
2023-08-11 |
Not clear |
| C E Jones, P A Gwirt. Alpha 1-adrenergic coronary constriction during exercise and ischemia. Basic research in cardiology. vol 85 Suppl 1. 1991-06-04. PMID:1965397. |
it was demonstrated that in the quiescent conscious dog, the coronary circulation is devoid of an alpha 1-coronary constriction. |
1991-06-04 |
2023-08-11 |
dog |
| G Heusch, A Deussen, B D Gut. Prevention of alpha-adrenergic coronary constriction by calcium-antagonists. Basic research in cardiology. vol 85 Suppl 1. 1991-06-04. PMID:1965399. |
alpha 1- and alpha 2-adrenergic coronary constriction also contribute to the severity of myocardial ischemia in conscious dogs during treadmill exercise. |
1991-06-04 |
2023-08-11 |
Not clear |
| R Seitelberger, B D Guth, G Heusch, J Ros. Alpha 2-adrenergic coronary constriction in ischemic myocardium during exercise. Basic research in cardiology. vol 85 Suppl 1. 1991-06-04. PMID:1982609. |
regional alpha 2-adrenoceptor blockade, but not alpha 1-adrenoceptor blockade is effective in reducing regional ischemia and dysfunction by attenuating sympathetic vasoconstriction in the conscious dog. |
1991-06-04 |
2023-08-11 |
dog |
| G B Glavin, J M Gerrar. Characterization of the gastroprotective effects of N,N-diethyl-2-[4-(phenylmethyl)phenoxy]-ethanamine hydrochloride, a non-H1/non-H2 histamine antagonist. Digestion. vol 47. issue 3. 1991-05-16. PMID:2083800. |
we now demonstrate that the antiulcer effects of dppe are associated with a dramatic (10-fold) rise in the stable prostacyclin hydration product 6-keto-prostaglandin f1 alpha in gastric secretion collected from conscious rats. |
1991-05-16 |
2023-08-11 |
rat |
| G Eisenhofer, T Saigusa, M D Esler, H S Cox, J A Angus, P K Dorwar. Central sympathoinhibition and peripheral neuronal uptake blockade after desipramine in rabbits. The American journal of physiology. vol 260. issue 4 Pt 2. 1991-05-09. PMID:1672797. |
peripheral- and central nervous system (cns)-mediated effects of desipramine (des) on sympathetic nerves and the contribution of alpha 2-adrenoceptors to these effects were studied in conscious rabbits. |
1991-05-09 |
2023-08-11 |
Not clear |
| V Rettori, M F Gimeno, A Karara, M C Gonzalez, S M McCan. Interleukin 1 alpha inhibits prostaglandin E2 release to suppress pulsatile release of luteinizing hormone but not follicle-stimulating hormone. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 7. 1991-05-06. PMID:1901415. |
we injected recombinant human il-1 alpha into the third cerebral ventricle, to study its effect on the pulsatile release of follicle-stimulating hormone (fsh) and luteinizing hormone (lh) in conscious, freely moving, ovariectomized rats. |
1991-05-06 |
2023-08-11 |
human |
| J C Eisenach, C Y Ton. Site of hemodynamic effects of intrathecal alpha 2-adrenergic agonists. Anesthesiology. vol 74. issue 4. 1991-05-02. PMID:1672580. |
to further characterize hemodynamic depression produced by intrathecally administered alpha 2-adrenergic agonists, clonidine (100-1,500 micrograms) was injected into the cervical, thoracic, or lumbar intrathecal space of conscious sheep. |
1991-05-02 |
2023-08-11 |
Not clear |
| N J Rothwel. Central activation of thermogenesis by prostaglandins: dependence on CRF. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 22. issue 12. 1991-04-22. PMID:2076859. |
central (intracerebroventricular) injections of pge2, pgf2 alpha caused dose dependent increases in oxygen consumption (vo2) and colonic temperature in conscious rats. |
1991-04-22 |
2023-08-11 |
rat |
| G W John, J C Doxey, D S Walter, J L Rei. Selective alpha 2-adrenoceptor blockade does not enhance glucose-evoked insulin release. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:1981556. |
an investigation has been made of the effects of the selective alpha 2-adrenoceptor antagonist, idazoxan, on the plasma immunoreactive insulin and glucose responses following a glucose stimulus in conscious euglycaemic rats. |
1991-04-15 |
2023-08-11 |
rat |
| M T Piascik, J W Kusiak, K W Barro. Alpha 1-adrenoceptor subtypes and the regulation of peripheral hemodynamics in the conscious rat. European journal of pharmacology. vol 186. issue 2-3. 1991-04-03. PMID:1981186. |
alpha 1-adrenoceptor subtypes and the regulation of peripheral hemodynamics in the conscious rat. |
1991-04-03 |
2023-08-11 |
rat |
| M T Piascik, J W Kusiak, K W Barro. Alpha 1-adrenoceptor subtypes and the regulation of peripheral hemodynamics in the conscious rat. European journal of pharmacology. vol 186. issue 2-3. 1991-04-03. PMID:1981186. |
the peripheral hemodynamic effects of szl-49, a prazosin analog capable of selectively inactivating the alpha 1a-adrenoceptor subtype, was evaluated in the conscious rat. |
1991-04-03 |
2023-08-11 |
rat |
| R Schulz, B D Guth, G Heusc. Pharmacological mechanisms to attenuate sympathetically induced myocardial ischemia. Cardiovascular drugs and therapy. vol 3. issue 1. 1991-03-28. PMID:2487523. |
in experimental studies in anesthetized, vagotomized dogs, as well as in conscious, chronically instrumented dogs, selective alpha 2-adrenoceptor antagonists and calcium-channel blockade with nifedipine were able to attenuate the sympathetically induced poststenotic myocardial ischemia. |
1991-03-28 |
2023-08-11 |
Not clear |