| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Herkes, C D Smith, L P Prabhakar, S F Phillips, M G Sar. Effect of alpha-methylnorepinephrine, an alpha 2-adrenergic agonist, on jejunal absorption in neurally intact conscious dog. Digestive diseases and sciences. vol 38. issue 9. 1993-09-30. PMID:8359076. |
our aim was to assess the effects of intravenous administration of alpha-methylnorepinephrine (mne), an alpha 2-adrenergic agonist that does not cross the blood-brain barrier, on net jejunal absorption of water and electrolytes in the neurally intact, conscious dog. |
1993-09-30 |
2023-08-12 |
dog |
| K J Slavik, J LaPoint. Involvement of inhibitory dopamine-2 receptors in resting bradycardia in exercise-conditioned rats. Journal of applied physiology (Bethesda, Md. : 1985). vol 74. issue 5. 1993-08-26. PMID:8101519. |
to accomplish this, preferential da2 and alpha 2-agonists and antagonists were administered at rest to conscious rats after they participated in an exercise conditioning program. |
1993-08-26 |
2023-08-12 |
rat |
| B G Benfe. Antifibrillatory effects of alpha 1-adrenoceptor blocking drugs in experimental coronary artery occlusion and reperfusion. Canadian journal of physiology and pharmacology. vol 71. issue 2. 1993-08-05. PMID:8100476. |
the effect of alpha 1-adrenoceptor blocking drugs on the incidence of ventricular fibrillation in acute coronary artery occlusion and (or) reperfusion has been determined in 24 studies in conscious and anesthetized dogs and rats, anesthetized cats and pigs, and rat and guinea-pig isolated hearts. |
1993-08-05 |
2023-08-12 |
rat |
| R G Evans, J M Haynes, J Ludbroo. Effects of 5-HT-receptor and alpha 2-adrenoceptor ligands on the haemodynamic response to acute central hypovolaemia in conscious rabbits. British journal of pharmacology. vol 109. issue 1. 1993-06-21. PMID:8388300. |
effects of 5-ht-receptor and alpha 2-adrenoceptor ligands on the haemodynamic response to acute central hypovolaemia in conscious rabbits. |
1993-06-21 |
2023-08-12 |
rabbit |
| R G Evans, J M Haynes, J Ludbroo. Effects of 5-HT-receptor and alpha 2-adrenoceptor ligands on the haemodynamic response to acute central hypovolaemia in conscious rabbits. British journal of pharmacology. vol 109. issue 1. 1993-06-21. PMID:8388300. |
we set out to elucidate the pharmacological mechanisms by which alpha 2-adrenoceptor and 5-ht-receptor ligands affect the haemodynamic response to acute central hypovolaemia in conscious rabbits. |
1993-06-21 |
2023-08-12 |
rabbit |
| I M Chapman, R Kapoor, J O Willoughb. Endogenous catecholamines modulate growth hormone release in the conscious rat during hypoglycaemia but not in the basal state. Journal of neuroendocrinology. vol 5. issue 2. 1993-06-04. PMID:8097943. |
to investigate the role of endogenous catecholamines and 5-hydroxytryptamine in the control of growth hormone (gh) secretion, secretory profiles of gh and prolactin were measured in conscious, male rats following intravenous administration of either 1) alpha 2 antagonist idazoxan 2 mg/kg, a dose that blocked alpha 2 agonist induced gh rise, 2) alpha 1 antagonist prazosin 1 mg/kg, 3) non-specific beta-blocker propranolol 1.5 mg/kg, a dose that prevented beta 2 agonist (salbutamol) induced inhibition, 4) serotonin antagonist cyproheptadine 0.5 mg/kg, a dose that inhibited serotonin agonist quipazine induced gh rise, or 5) control. |
1993-06-04 |
2023-08-12 |
rat |
| R Kapoor, I M Chapman, J O Willoughb. Alpha 2 and beta adrenoceptors in the mediobasal hypothalamus and alpha 2 adrenoceptors in the preoptic-anterior hypothalamus stimulate prolactin secretion in the conscious male rat. Journal of neuroendocrinology. vol 5. issue 2. 1993-06-04. PMID:8097944. |
alpha 2 and beta adrenoceptors in the mediobasal hypothalamus and alpha 2 adrenoceptors in the preoptic-anterior hypothalamus stimulate prolactin secretion in the conscious male rat. |
1993-06-04 |
2023-08-12 |
rat |
| K C Lee, D C Randal. Potentiation of the pressor response to stress by tolbutamide in dogs. Integrative physiological and behavioral science : the official journal of the Pavlovian Society. vol 28. issue 1. 1993-05-24. PMID:8476738. |
tolbutamide has previously been shown to amplify the pressor effects of "exogenous" catecholamines in conscious dogs, possibly due to sensitization of the alpha 1-adrenoreceptor-mediated vasoconstriction. |
1993-05-24 |
2023-08-12 |
Not clear |
| K C Lee, D C Randal. Potentiation of the pressor response to stress by tolbutamide in dogs. Integrative physiological and behavioral science : the official journal of the Pavlovian Society. vol 28. issue 1. 1993-05-24. PMID:8476738. |
in conclusion, tolbutamide amplifies the pressor effects of "endogenous" catecholamines in conscious dogs, possibly by sensitization of the alpha 1-adrenoreceptor-mediated vasoconstriction. |
1993-05-24 |
2023-08-12 |
Not clear |
| N Uemura, D E Vatner, Y T Shen, J Wang, S F Vatne. Increased alpha 1-adrenergic vascular sensitivity during development of hypertension in conscious dogs. The American journal of physiology. vol 264. issue 4 Pt 2. 1993-05-17. PMID:8386482. |
increased alpha 1-adrenergic vascular sensitivity during development of hypertension in conscious dogs. |
1993-05-17 |
2023-08-12 |
Not clear |
| K Nishiwaki, D P Nyhan, R S Stuart, P M Desai, W P Peterson, P Rock, C G Pribble, P A Murra. Pulmonary vascular alpha 1-adrenoreceptor activity in conscious dogs after left lung autotransplantation. Journal of applied physiology (Bethesda, Md. : 1985). vol 74. issue 2. 1993-04-27. PMID:8384615. |
pulmonary vascular alpha 1-adrenoreceptor activity in conscious dogs after left lung autotransplantation. |
1993-04-27 |
2023-08-12 |
Not clear |
| K Nishiwaki, D P Nyhan, R S Stuart, P M Desai, W P Peterson, P Rock, C G Pribble, P A Murra. Pulmonary vascular alpha 1-adrenoreceptor activity in conscious dogs after left lung autotransplantation. Journal of applied physiology (Bethesda, Md. : 1985). vol 74. issue 2. 1993-04-27. PMID:8384615. |
we investigated the extent to which sympathetic alpha 1-adrenoreceptor activation is involved in chronic pulmonary vascular regulation in conscious dogs after left lung autotransplantation (lla). |
1993-04-27 |
2023-08-12 |
Not clear |
| T Harada, C E Constantino. The effect of alpha 2 agonists and antagonists on the lower urinary tract of the rat. The Journal of urology. vol 149. issue 1. 1993-01-25. PMID:8093264. |
the pharmacologic potential of selective alpha 2 adrenergic agents in modulating vesicourethral function was evaluated in urethane-anesthetized and conscious rats. |
1993-01-25 |
2023-08-12 |
rat |
| T Harada, C E Constantino. The effect of alpha 2 agonists and antagonists on the lower urinary tract of the rat. The Journal of urology. vol 149. issue 1. 1993-01-25. PMID:8093264. |
in conscious rats, the alpha 2 agonist produced urinary dribbling at approximately 20 minutes after sc injection, while the antagonists produced delayed dribbling 70 minutes after sc injection. |
1993-01-25 |
2023-08-12 |
rat |
| K J Slavik, J E Szilagy. Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors. The Journal of pharmacology and experimental therapeutics. vol 263. issue 3. 1993-01-22. PMID:1335070. |
into conscious rats results in a bradycardia that has a peripheral component, is dependent on a certain level of sympathetic activity and is sensitive to alpha adrenoceptor blockade (5 mg/kg of phentolamine i.v.). |
1993-01-22 |
2023-08-11 |
rat |
| M N Sharif, R D Kaushal, P Iyer, T W Wilso. Diltiazem potentiates angiotensin II-mediated renal prostacyclin synthesis. Journal of cardiovascular pharmacology. vol 20. issue 4. 1993-01-07. PMID:1280721. |
we examined interactions between aii and dil on [14c]p-aminohippurate ([14c]pah) clearance, mean arterial pressure (map), and urine 6-ketoprostaglandin f1 alpha excretion (u6k) in groups of seven to nine conscious sprague-dawley rats. |
1993-01-07 |
2023-08-11 |
rat |
| H Kawasaki, S Nakamura, K Takasak. Central alpha 2-adrenoceptor-mediated pressor response to clonidine in conscious, spontaneously hypertensive rats. Japanese journal of pharmacology. vol 59. issue 3. 1992-12-10. PMID:1331587. |
central alpha 2-adrenoceptor-mediated pressor response to clonidine in conscious, spontaneously hypertensive rats. |
1992-12-10 |
2023-08-11 |
rat |
| K Gradin, A P Nicholas, P Hjemdahl, T Svensson, T Hökfel. Contrasting cardiovascular responses from intrathecal administration of epinephrine and norepinephrine in conscious rats: role of alpha 1- and alpha 2-adrenoceptors. Journal of cardiovascular pharmacology. vol 20. issue 3. 1992-12-09. PMID:1279280. |
contrasting cardiovascular responses from intrathecal administration of epinephrine and norepinephrine in conscious rats: role of alpha 1- and alpha 2-adrenoceptors. |
1992-12-09 |
2023-08-11 |
rat |
| A Abdelrahman, C C Pan. Calcitonin gene-related peptide is a venous dilator in conscious rats. European journal of pharmacology. vol 217. issue 2-3. 1992-12-04. PMID:1358633. |
this study examines the dose-response effects of rat alpha cgrp on mean circulatory filling pressure (mcfp), an index of body venous tone, in conscious rats. |
1992-12-04 |
2023-08-11 |
rat |
| J K Callaway, R G Kin. Effects of inhaled alpha 2-adrenoceptor and GABAB receptor agonists on citric acid-induced cough and tidal volume changes in guinea pigs. European journal of pharmacology. vol 220. issue 2-3. 1992-12-01. PMID:1358650. |
the effects of alpha 2-adrenoceptor and gaba receptor agonists on citric acid-induced cough and increased tidal volume were investigated in conscious guinea pigs. |
1992-12-01 |
2023-08-11 |
Not clear |