| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C H Cheng, B Costall, M E Kelly, R J Naylo. Actions of 5-hydroxytryptophan to inhibit and disinhibit mouse behaviour in the light/dark test. European journal of pharmacology. vol 255. issue 1-3. 1994-08-08. PMID:7913044. |
the involvement of 5-ht receptors in behavioural responding to an aversive situation was investigated in the mouse light/dark test. |
1994-08-08 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. European journal of pharmacology. vol 253. issue 1-2. 1994-07-26. PMID:8013551. |
pre-exposure to 5-hydroxytryptamine (5-ht) receptor agonists in conditioned taste aversion experiments was used to characterize the stimulus properties of fluoxetine. |
1994-07-26 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. European journal of pharmacology. vol 253. issue 1-2. 1994-07-26. PMID:8013551. |
pre-exposure to mk 212 also prevented the conditioned taste aversion induced by another serotonin uptake inhibitor, paroxetine. |
1994-07-26 |
2023-08-12 |
mouse |
| I Lucki, A Singh, D S Kreis. Antidepressant-like behavioral effects of serotonin receptor agonists. Neuroscience and biobehavioral reviews. vol 18. issue 1. 1994-06-01. PMID:8170624. |
the second approach for studying the behavioral effects of antidepressant drugs employs drug discrimination studies, conducted using a discriminated taste aversion procedure, to provide a method for studying the discriminative stimulus effects of the antidepressant 5-ht uptake inhibitor sertraline. |
1994-06-01 |
2023-08-12 |
rat |
| V Paul, E Balasubramaniam, M Kaz. The neurobehavioural toxicity of endosulfan in rats: a serotonergic involvement in learning impairment. European journal of pharmacology. vol 270. issue 1. 1994-05-17. PMID:8157075. |
the escape response but not the avoidance response was reinstated significantly by the 5-hydroxytryptamine (5-ht) depletor, p-chlorophenylalanine (pcpa, 100 mg/kg per day for 3 days). |
1994-05-17 |
2023-08-12 |
rat |
| A A Alhaider, A M Ageel, O T Ginaw. The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors. Neuropharmacology. vol 32. issue 12. 1994-05-10. PMID:8152532. |
the role of serotonin (5-ht) in the acquisition of the conditioned avoidance response was investigated. |
1994-05-10 |
2023-08-12 |
rat |
| A A Alhaider, A M Ageel, O T Ginaw. The quipazine- and TFMPP-increased conditioned avoidance response in rats: role of 5HT1C/5-HT2 receptors. Neuropharmacology. vol 32. issue 12. 1994-05-10. PMID:8152532. |
increased acquisition of conditioned avoidance induced by either quipazine or tfmpp was effectively antagonized by the mixed 5-ht 1c/2 receptor antagonists, ketanserin (0.2 and 2 mg/kg, s.c.) and mianserin (1 mg/kg, s.c.). |
1994-05-10 |
2023-08-12 |
rat |
| F S Guimarães, E A Del Bel, C M Padovan, S M Netto, R T de Almeid. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136041. |
it has been suggested that postsynaptic 5-ht1a receptors in the hippocampus, innervated by 5-ht neurons localized in the median raphe nucleus, mediate adaptive or coping responses to aversive events and that dysfunction of this system is related to symptoms of depression. |
1994-04-25 |
2023-08-12 |
rat |
| F S Guimarães, E A Del Bel, C M Padovan, S M Netto, R T de Almeid. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136041. |
to investigate the role of 5-ht neurotransmission in the hippocampus on adaptation to aversive events we immobilized rats for 2 h and tested them 24 h later in an elevated plus-maze. |
1994-04-25 |
2023-08-12 |
rat |
| S L Handley, J W McBlane, M A Critchley, K Njung'. Multiple serotonin mechanisms in animal models of anxiety: environmental, emotional and cognitive factors. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136047. |
it is possible that cognitive factors may affect stimulus evaluation, and response inhibition by an aversive stimulus may be a special case of a wider role for serotonin in behavioural control. |
1994-04-25 |
2023-08-12 |
Not clear |
| M L Brandão, L L Melo, S H Cardos. Mechanisms of defense in the inferior colliculus. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136049. |
serotonergic mechanisms seem also to be involved in the modulation of these aversive states as ic microinjections of zimelidine, a 5-ht uptake blocker, caused a significant inhibition of the switch-off responses in the shuttle-box. |
1994-04-25 |
2023-08-12 |
rat |
| C M Padovan, F S Guimarãe. Attenuation of behavioral consequences of immobilization stress by intra-hippocampal microinjection of zimelidine. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 26. issue 10. 1994-03-24. PMID:8312840. |
to investigate the role of hippocampal 5-ht neurotransmission on adaptation to aversive events, individually housed male wistar rats (200-250 g) were immobilized for 2 h and tested 24 h later in an elevated plus-maze. |
1994-03-24 |
2023-08-12 |
rat |
| P Jäkälä, M Mazurkiewicz, J Sirviö, P Riekkinen, P Riekkine. The behavioral effects of serotonin synthesis inhibition and quisqualic acid induced lesions of the nucleus basalis magnocellularis in rats. General pharmacology. vol 24. issue 5. 1994-02-01. PMID:8270173. |
to investigate the role of the cholinergic and serotonergic systems in the regulation of cognitive functions, the effects of concurrent lesioning of nucleus basalis magnocellularis (nb) with quisqualic acid (quis) and inhibition of brain serotonin synthesis by systemic p-chlorophenylalanine (pcpa) treatment on passive avoidance (pa) retention and water maze (wm) spatial navigation performance were studied in rats. |
1994-02-01 |
2023-08-12 |
rat |
| T C Ma, Q H Y. Effect of 20(S)-ginsenoside-Rg2 and cyproheptadine on two-way active avoidance learning and memory in rats. Arzneimittel-Forschung. vol 43. issue 10. 1994-01-25. PMID:8267667. |
the results also provide the suggestive evidence that central serotonin may play a positive modulatory role in the acquisition, retention and retrieval of two-way active avoidance responding in rats. |
1994-01-25 |
2023-08-12 |
rat |
| M Riekkinen, J Sirviö, P Riekkine. Pharmacological consequences of nicotinergic plus serotonergic manipulations. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:8242353. |
the present study investigates the effects of concurrent manipulations of nicotinic cholinergic receptors (nicotinic cholinergic agonist: nicotine 0.03, 0.1, 0.3 mg/kg, nicotinic cholinergic antagonist: mecamylamine 7.5 mg/kg) and serotonin neurons (p-chlorophenylalanine (pcpa), 400/kg mg on each of 3 days) on spatial navigation (water maze, wm) and passive avoidance (pa) performance. |
1994-01-06 |
2023-08-12 |
rat |
| N A Kharin, A T Dolzhenko, A V Titievskiĭ, S V Naleto. [The possible neurochemical mechanisms of the neuroleptic action of buspirone-like serotonin agonists]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 4. 1993-12-20. PMID:8106056. |
the serotonin agonists under study accelerate rat brain dopamine metabolism show their antagonism with apomorphine in the stereotypy and climbing tests in mice, suppress the conditioned avoidance reflex in rats, and eliminate apomorphine-induced vomiting in pigeons. |
1993-12-20 |
2023-08-12 |
mouse |
| A N Talalaenk. [The neurochemical profile of the dorsal hippocampus and the antiaversive effects of anxiolytics in different models of anxiety in rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 43. issue 3. 1993-09-30. PMID:8103252. |
chemical stimulation of the dorsal hippocampus by serotonin and gaba decreases anxiety in a test of avoidance of precarious situation but not of illuminated platform. |
1993-09-30 |
2023-08-12 |
rat |
| A N Talalaenko, N A Khari. [The mechanisms of the anxiolytic action of 1-(2-pyrimidinyl)-piperazine derivatives, serotonin agonists]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 2. 1993-09-14. PMID:8102289. |
5-ht locally injected into the nucleus raphe and hippocampus revealed a role of serotoninergic mechanisms of these brain formations in the studied anxiety conditions of different aversive genesis. |
1993-09-14 |
2023-08-12 |
rat |
| S D Mendelson, D Quartermain, T Francisco, A Sheme. 5-HT1A receptor agonists induce anterograde amnesia in mice through a postsynaptic mechanism. European journal of pharmacology. vol 236. issue 2. 1993-08-05. PMID:8319749. |
treatment with the 5-ht synthesis inhibitor pcpa (parachlorophenylalanine) resulted in apparent enhancement rather than disruption of the avoidance behavior. |
1993-08-05 |
2023-08-12 |
mouse |
| b' A N Talalaenko, G K Krivobok, Iu V Stakhovski\\xc4\\xa. [The role of monoamin- and acidergic mechanisms of the hippocampus in anxiety states of different origins and their participation in the antiaversive effects of anxiolytics]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 79. issue 1. 1993-07-28. PMID:8100168.' |
the experiments on rats with tests of avoiding "lighting square" and "threatening situation" and with the chemical stimulation of dorsal and ventral hippocampus with dopamine, 5-ht, gaba and glutamine acid, showed different functional significance of these monoamines and acidergic transmitters agents in the states of anxiety of heteromodal aversive genesis. |
1993-07-28 |
2023-08-12 |
rat |