| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Ge, N M Barnes, B Costall, R J Naylo. Effect of aversive stimulation on 5-hydroxytryptamine and dopamine metabolism in the rat brain. Pharmacology, biochemistry, and behavior. vol 58. issue 3. 1998-02-06. PMID:9329072. |
it is concluded that the aversive test condition of the social interaction test (hu) increases 5-ht and da turnover throughout the rat brain. |
1998-02-06 |
2023-08-12 |
rat |
| F G Graeff, M B Viana, P O Mor. Dual role of 5-HT in defense and anxiety. Neuroscience and biobehavioral reviews. vol 21. issue 6. 1998-02-04. PMID:9415904. |
in contrast, results with intracerebral drug injection associated with aversive electrical brain stimulation indicate that 5-ht inhibits aversion in the dorsal periaqueductal gray (dpag). |
1998-02-04 |
2023-08-12 |
Not clear |
| F G Graeff, M B Viana, P O Mor. Dual role of 5-HT in defense and anxiety. Neuroscience and biobehavioral reviews. vol 21. issue 6. 1998-02-04. PMID:9415904. |
in contrast, reduction of 5-ht release by intra-dr injection of 8-oh-dpat impaired inhibitory avoidance without affecting one-way escape. |
1998-02-04 |
2023-08-12 |
Not clear |
| P O Mora, C F Netto, F G Graef. Role of 5-HT2A and 5-HT2C receptor subtypes in the two types of fear generated by the elevated T-maze. Pharmacology, biochemistry, and behavior. vol 58. issue 4. 1998-01-30. PMID:9408213. |
inhibitory avoidance was impaired by the selective 5-ht2c antagonists sb 200646a (3.0-30 mg/kg) and sdz ser 082 (0.1-1.0 mg/kg), by the 5-ht2a antagonist sr 46349b (1.0-10.0 mg/kg), and by the mixed 5-ht(2a,2c) antagonist ritanserin (0.3-3.0 mg/kg). |
1998-01-30 |
2023-08-12 |
rat |
| H H Berendsen, C L Broekkam. Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine. Psychopharmacology. vol 133. issue 3. 1998-01-07. PMID:9361334. |
in the cross-familiarization conditioned taste aversion experiments it was found that the conditioned taste aversion induced by mirtazapine (0.32 mg/kg) could be prevented if the mice were pre-exposed to injections with mirtazapine (0.22 and 0.46 mg/kg), 8-oh-dpat (0.22 and 0.46 mg/kg) and after pre-exposure to the 5-ht reuptake inhibitor fluoxetine (22 mg/kg). |
1998-01-07 |
2023-08-12 |
mouse |
| L Johansson, D Sohn, S O Thorberg, D M Jackson, D Kelder, L G Larsson, L Rényi, S B Ross, C Wallsten, H Eriksson, P S Hu, E Jerning, N Mohell, A Westlind-Danielsso. The pharmacological characterization of a novel selective 5-hydroxytryptamine1A receptor antagonist, NAD-299. The Journal of pharmacology and experimental therapeutics. vol 283. issue 1. 1997-11-03. PMID:9336327. |
thus, they competitively antagonized the 8-hydroxy-2-(di-n-propylamino)tetralin-induced 5-ht behavioral effects, hypothermia, corticosterone secretion and inhibition of passive avoidance behavior without causing any actions of their own. |
1997-11-03 |
2023-08-12 |
Not clear |
| A N Talalaenko, V Iu Panfilov, S A Vozdigan, A I Pokramovich, O P Markova, S V Okhrimenk. [The neurochemical profile of the septal nucleus accumbens in the anxiolytic action of tranquilizers on different models of anxiety]. Eksperimental'naia i klinicheskaia farmakologiia. vol 60. issue 4. 1997-10-28. PMID:9376765. |
local injections of chlordiazepoxide, pnenibut, indoter, campiron, and campironin into the nucleus weakened the alarm in the test for avoidance of an "illuminated area" and/or a "threatening situation", showing a similarity to the effects of gaba and serotonin but not to those of mesaton (phenylephrine hydrochloride) and dopamine. |
1997-10-28 |
2023-08-12 |
rat |
| M M Hämäläinen, T A Lovic. Involvement of nitric oxide and serotonin in modulation of antinociception and pressor responses evoked by stimulation in the dorsolateral region of the periaqueductal gray matter in the rat. Neuroscience. vol 80. issue 3. 1997-10-27. PMID:9276497. |
nitric oxide may act in association with 5-hydroxytryptamine to control the excitability of the aversive system in the midbrain. |
1997-10-27 |
2023-08-12 |
rat |
| E M Blain. Acute severe depression following peri-operative ondansetron. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 87. issue 8. 1997-10-23. PMID:9323412. |
anaesthesia with a propofol infusion and avoidance of serotonin antagonists provided a nausea-free postoperative course without exacerbation of the depression disorder. |
1997-10-23 |
2023-08-12 |
Not clear |
| M B Viana, F G Graeff, P A Löschman. Kainate microinjection into the dorsal raphe nucleus induces 5-HT release in the amygdala and periaqueductal gray. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264086. |
because only intra-drn kainate both increased inhibitory avoidance and decreased one-way escape in the elevated t-maze, the present behavioral results support the suggestion that 5-ht facilitates conditioned fear in the am and inhibits unconditioned fear in the dpag. |
1997-09-30 |
2023-08-12 |
rat |
| A Rex, C A Marsden, H Fin. Cortical 5-HT-CCK interactions and anxiety-related behaviour of guinea-pigs: a microdialysis study. Neuroscience letters. vol 228. issue 2. 1997-08-25. PMID:9209103. |
there are only few data suggesting interactions between cck and 5-ht under aversive conditions. |
1997-08-25 |
2023-08-12 |
Not clear |
| A C McCreary, J W McBlane, H A Spooner, S L Handle. 5-HT systems and anxiety: multiple mechanisms in the elevated X-maze. Polish journal of pharmacology. vol 48. issue 1. 1997-07-03. PMID:9112622. |
the recent idea that 5-ht neurones, alerted by the forebrain, also function to restrain more primitive brainstem mechanisms has additional explanatory power but neither proposal accounts for the lack of responsiveness of 5-ht neurones to aversive stimulation from the environment. |
1997-07-03 |
2023-08-12 |
Not clear |
| S Beckett, C A Marsde. The effect of central and systemic injection of the 5-HT1A receptor agonist 8-OHDPAT and the 5-HT1A receptor antagonist WAY100635 on periaqueductal grey-induced defence behaviour. Journal of psychopharmacology (Oxford, England). vol 11. issue 1. 1997-06-19. PMID:9097891. |
these data support previous findings which indicate that serotonergic modulation of aversive behaviours such as defence can be mediated by 5-ht(1a) receptors. |
1997-06-19 |
2023-08-12 |
rat |
| H Furuya, H Aikawa, T Yoshida, I Okazak. Effects of ethyl alcohol administration to THA rat dams during their gestation period on learning behavior and on levels of monoamines and metabolites in the brain of pups after birth. Alcoholism, clinical and experimental research. vol 20. issue 9 Suppl. 1997-04-09. PMID:8986228. |
sidman avoidance behavior test and the levels of monoamines (nor-adrenalin, dopamine, and serotonin) and metabolites (3, 4-dihydroxyphenyl acetic acid, homovanillic acid, and 5-hydroxyindole acetic acid) in whole brain were examined for neurobehavioral and neurochemical effects. |
1997-04-09 |
2023-08-12 |
rat |
| D C Cara, A A Conde, N M Va. Immunological induction of flavour aversion in mice. II. Passive/adoptive transfer and pharmacological inhibition. Scandinavian journal of immunology. vol 45. issue 1. 1997-02-21. PMID:9010495. |
in immunized animals, gavage or voluntary ingestion of ovalbumin triggers an increase of vascular permeability in the intestine; pretreatment with a mixture of histamine and serotonin antagonists blocked this reaction, but not the aversion; dexamethasone inhibited both the aversion and the increase in permeability. |
1997-02-21 |
2023-08-12 |
mouse |
| T Oyama, M Ueda, Y Kuraishi, A Akaike, M Sato. Dual effect of serotonin on formalin-induced nociception in the rat spinal cord. Neuroscience research. vol 25. issue 2. 1996-12-13. PMID:8829149. |
intrathecal administration of 5-ht showed a dual effect on the second phase of the aversive responses in the 5,7-dht-treated rats; 5-ht inhibited the aversive responses when administered at a low dose (0.1 nmol/rat) but facilitated them at a high dose (1 nmol/rat). |
1996-12-13 |
2023-08-12 |
rat |
| J A Harve. Serotonergic regulation of associative learning. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788476. |
this paper presents a review of studies dealing with the effects of 5-ht agonists and antagonists on learning as measured by classical conditioning of the rabbit's nictitating membrane response or the conditioned avoidance response in the rat. |
1996-12-04 |
2023-08-12 |
rat |
| M A Prendergast, S E Hendricks, D P Yells, S Balog. Conditioned taste aversion induced by fluoxetine. Physiology & behavior. vol 60. issue 1. 1996-12-04. PMID:8804682. |
the present study assessed the ability of the serotonin reuptake inhibitor fluoxetine (flx) and lithium chloride (licl) to induce conditioned taste aversion (cta) to a novel 20% sucrose solution. |
1996-12-04 |
2023-08-12 |
rat |
| L S Wilkinson, T Humby, S Killcross, T W Robbins, B J Everit. Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli. The European journal of neuroscience. vol 8. issue 7. 1996-11-06. PMID:8758955. |
exposure to the aversive environment, but not to either of the two neutral environments, was associated with significantly increased hippocampal 5-hydroxytryptamine release in long-trace subjects. |
1996-11-06 |
2023-08-12 |
human |
| L S Wilkinson, T Humby, S Killcross, T W Robbins, B J Everit. Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli. The European journal of neuroscience. vol 8. issue 7. 1996-11-06. PMID:8758955. |
these data do not agree with the hypothesis that aversive cues generally activate 5-hydroxytryptamine function in the hippocampus. |
1996-11-06 |
2023-08-12 |
human |