| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fengting Su, Hubert Descher, Minh Bui-Hoang, Hermann Stuppner, Ira Skvortsova, Ehsan Bonyadi Rad, Claudia Ascher, Alexander Weiss, Zhigang Rao, Stephan Hohloch, Solveigh C Koeberle, Ronald Gust, Andreas Koeberl. Iron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors. Redox biology. vol 75. 2024-07-02. PMID:38955113. |
chlorido [n,n'-disalicylidene-1,2-phenylenediamine]iron (iii) complexes (scs) have potent anti-cancer properties by inducing ferroptosis, apoptosis, or necroptosis through still poorly understood molecular mechanisms. |
2024-07-02 |
2024-07-06 |
Not clear |
| Tan Ma, Huixian Cheng, Liang Kong, Chenghao Shen, Haibo Jin, Hongliang Li, Chun Pan, Jingyan Lian. Combined exposure of PS-MPs with NaF induces Sertoli cell death and dysfunction via ferroptosis and apoptosis. Toxicology. 2024-05-31. PMID:38821197. |
our in vitro studies showed that naf (21μg/ml) and mps (100μg/ml) synergistically induced scs apoptosis and ferroptosis, leading to a reduction in scs number and dysfunction. |
2024-05-31 |
2024-06-02 |
mouse |
| Qiu Yan, Qi Wang, Jinghong Nan, Tingting Chen, Juntao Wang, Yong Zhang, Ligang Yua. Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mTOR signaling pathway of yak Sertoli cells. Theriogenology. vol 220. 2024-03-19. PMID:38503100. |
next, we investigated the expression of ho1 in the scs exposed to hypoxic stress and characterized the expression of key molecules involved in autophagy and apoptosis. |
2024-03-19 |
2024-03-23 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
we found that cd treatment caused a significant increase of apoptosis in scs cells, accompanied by a marked increase in the production of ros. |
2024-02-17 |
2024-02-20 |
Not clear |
| Na Chen, Xiaoyan Wan, Shun Cheng, Guiju Tang, Dan Xia, Yanling Xu, Yi She. Defective autophagic flux aggravates cadmium-induced Sertoli cell apoptosis. Ecotoxicology and environmental safety. vol 273. 2024-02-17. PMID:38367604. |
together, this study provides insight into the negative effects of cd, which interferes with autophagic flux and induces the apoptosis of scs. |
2024-02-17 |
2024-02-20 |
Not clear |
| Anna Calabrò, Giulia Accardi, Anna Aiello, Calogero Caruso, Damiano Galimberti, Giuseppina Candor. Senotherapeutics to Counteract Senescent Cells Are Prominent Topics in the Context of Anti-Ageing Strategies. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339070. |
an escalating effort has been dedicated to identify senotherapeutics that selectively target scs by inducing apoptosis; these drugs are termed senolytics. |
2024-02-10 |
2024-02-12 |
Not clear |
| Su-Su Huang, Xue-Ru Wang, Jiu-Shu Yuan, Lian D. [Experimental research progress in traditional Chinese medicine prevention and treatment of diabetic peripheral neuropathy based on autophagy]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 23. 2024-01-11. PMID:38211988. |
it involves a variety of pathological changes such as oxidative stress, endoplasmic reticulum stress, neuroinflammation, and apoptosis of schwann cells(scs). |
2024-01-11 |
2024-01-14 |
Not clear |
| Su-Su Huang, Xue-Ru Wang, Jiu-Shu Yuan, Lian D. [Experimental research progress in traditional Chinese medicine prevention and treatment of diabetic peripheral neuropathy based on autophagy]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 23. 2024-01-11. PMID:38211988. |
the recent studies have confirmed that some active ingredients in traditional chinese medicines and tcm compound prescriptions can inhibit the oxidative stress, endoplasmic reticulum stress, mitochondrial damage, inflammation, and apoptosis of scs in dpn by regulating the autophagy pathway, thus playing a role in the prevention and treatment of dpn. |
2024-01-11 |
2024-01-14 |
Not clear |
| Lei Wei, Zonggang Feng, Qian Dou, Li Tan, Xinghua Zhao, Bin Ha. Dysregulation of MTFR2, ATP5IF1 and BAK1 in Sertoli cells relates to idiopathic non-obstructive azoospermia via inhibiting mitochondrial fission and inducing mitochondrial dysfunction. Biology of reproduction. 2023-10-30. PMID:37903059. |
cell viability, apoptosis, mitochondria membrane potential, atp production, oxygen consumption and mitochondria morphology were examined in primary human scs. |
2023-10-30 |
2023-11-08 |
mouse |
| Lei Wei, Zonggang Feng, Qian Dou, Li Tan, Xinghua Zhao, Bin Ha. Dysregulation of MTFR2, ATP5IF1 and BAK1 in Sertoli cells relates to idiopathic non-obstructive azoospermia via inhibiting mitochondrial fission and inducing mitochondrial dysfunction. Biology of reproduction. 2023-10-30. PMID:37903059. |
scs from patients with inoa had reduced viability, mitochondria membrane potential, atp production, oxygen consumption rate (ocr), glycolysis and increased apoptosis. |
2023-10-30 |
2023-11-08 |
mouse |
| Hongxia Gao, Yaqiong Liu, Wenchao Guan, Shaolan Sun, Tiantian Zheng, Linliang Wu, Guicai L. Surface topologized ovalbumin scaffolds containing YIGSR peptides for modulating Schwann cell behavior. International journal of biological macromolecules. vol 253. issue Pt 4. 2023-09-30. PMID:37758111. |
the results showed that the scaffolds prepared in this study had aligned ridge/groove structure, good mechanical properties and biocompatibility, and could be used as carriers to slowly release yigsr, which effectively promoted the proliferation, migration and elongation of schwann cells (scs), and significantly up-regulated the gene expression related to proliferation, apoptosis, migration and axon regeneration. |
2023-09-30 |
2023-10-07 |
Not clear |
| Ming-Yue Tian, Yi-Duo Yang, Wan-Ting Qin, Bao-Nian Liu, Fang-Fang Mou, Jing Zhu, Hai-Dong Guo, Shui-Jin Sha. Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury. Molecular neurobiology. 2023-09-06. PMID:37672149. |
on the other hand, both silencing gas5 and introducing a mir-21 mimic prominently enhanced the proliferation activity and migration ability of schwann cells (scs), while also inhibiting scs apoptosis. |
2023-09-06 |
2023-10-07 |
Not clear |
| Ming-Yue Tian, Yi-Duo Yang, Wan-Ting Qin, Bao-Nian Liu, Fang-Fang Mou, Jing Zhu, Hai-Dong Guo, Shui-Jin Sha. Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury. Molecular neurobiology. 2023-09-06. PMID:37672149. |
on the contrary, inhibition of scs apoptosis was found to be mediated by mir-21. |
2023-09-06 |
2023-10-07 |
Not clear |
| Ming-Yue Tian, Yi-Duo Yang, Wan-Ting Qin, Bao-Nian Liu, Fang-Fang Mou, Jing Zhu, Hai-Dong Guo, Shui-Jin Sha. Electroacupuncture Promotes Nerve Regeneration and Functional Recovery Through Regulating lncRNA GAS5 Targeting miR-21 After Sciatic Nerve Injury. Molecular neurobiology. 2023-09-06. PMID:37672149. |
mechanistically, the gas5/mir-21 axis can modulate the proliferation, migration, and apoptosis of scs while potentially influencing the neurite growth of neurons. |
2023-09-06 |
2023-10-07 |
Not clear |
| Nasim Alipour, Somaye Fallahnezhad, Javad Bagheri, Hamideh Babaloo, Fatemeh Tahmasebi, Ghasem Sazegar, Hossein Haghi. Increased Apoptosis in Subcortical Regions of The Visual Pathway in Offspring Born to Diabetic Rats. Cell journal. vol 25. issue 8. 2023-08-29. PMID:37641418. |
this study aimed to investigate the impact of maternal diabetes on neuronal apoptosis in the superior colliculus (sc) and the lateral geniculate nucleus (lgn) in male neonates born to diabetic mothers. |
2023-08-29 |
2023-09-07 |
rat |
| Sirao Hai, Jiawen Chen, Li Ma, Chenlong Wang, Chuangjiang Chen, Sajid Ur Rahman, Chang Zhao, Shibin Feng, Jinjie Wu, Xichun Wan. Combination of Zearalenone and Deoxynivalenol Induces Apoptosis by Mitochondrial Pathway in Piglet Sertoli Cells: Role of Endoplasmic Reticulum Stress. Toxins. vol 15. issue 7. 2023-07-28. PMID:37505740. |
this study aimed to explore the regulatory mechanism of endoplasmic reticulum stress (ers) on zea- combined with don-induced mitochondrial pathway apoptosis in piglet sertoli cells (scs). |
2023-07-28 |
2023-08-14 |
Not clear |
| Sabrina Petricca, Veronica Carnicelli, Carla Luzi, Benedetta Cinque, Giuseppe Celenza, Roberto Iori. Oxidative Stress, Cytotoxic and Inflammatory Effects of Azoles Combinatorial Mixtures in Sertoli TM4 Cells. Antioxidants (Basel, Switzerland). vol 12. issue 6. 2023-06-28. PMID:37371872. |
concerning male reproduction, a combinatorial activity of tebuconazole (teb; triazole fungicide) and econazole (eco; imidazole compound) in inducing mitochondrial impairment, energy depletion, cell cycle arrest, and the sequential activation of autophagy and apoptosis in sertoli tm4 cells (scs) has recently been demonstrated. |
2023-06-28 |
2023-08-14 |
Not clear |
| Sabrina Petricca, Veronica Carnicelli, Carla Luzi, Benedetta Cinque, Giuseppe Celenza, Roberto Iori. Oxidative Stress, Cytotoxic and Inflammatory Effects of Azoles Combinatorial Mixtures in Sertoli TM4 Cells. Antioxidants (Basel, Switzerland). vol 12. issue 6. 2023-06-28. PMID:37371872. |
furthermore, pre-treatment with n-acetylcysteine (nac) mitigates ros accumulation, attenuates cox-2 expression and tnf-α production, and rescues scs from azole-induced apoptosis, suggesting a ros-dependent molecular mechanism underlying the azole-induced cytotoxicity. |
2023-06-28 |
2023-08-14 |
Not clear |
| Baoyan Fan, Michael Chopp, Yi Zhang, Xinli Wang, Amy Kemper, Zheng Gang Zhang, Xian Shuang Li. Ablation of Argonaute 2 in Schwann cells accelerates the progression of diabetic peripheral neuropathy. Glia. 2023-05-13. PMID:37178056. |
in vitro data showed that knockdown of mir-200 induced mitochondrial dysfunction and apoptosis in scs. |
2023-05-13 |
2023-08-14 |
mouse |
| Haili Xiao, Chao Wei, Huiying Liu, Zhiqiang Li, Cihua Zheng, Jun Lu. Lentinan alleviates sciatic nerve injury by promoting autophagy to remove myelin fragments. Phytotherapy research : PTR. 2023-05-11. PMID:37165703. |
our results showed that lentinan promotes autophagic flux in vivo via the ampk/mtor signaling pathway, accelerates the clearance of myelin debris by scs, and inhibits neuronal apoptosis, thereby promoting neurological recovery. |
2023-05-11 |
2023-08-14 |
rat |