All Relations between apoptosis and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Fei Xie, Bin Liu, Wen Qiao, Jing-Zhen He, Jie Cheng, Zhao-Yang Wang, Ya-Min Hou, Xu Zhang, Bo-Han Xu, Yun Zhang, Yu-Guo Chen, Ming-Xiang Zhan. Smooth muscle NF90 deficiency ameliorates diabetic atherosclerotic calcification in male mice via FBXW7-AGER1-AGEs axis. Nature communications. vol 15. issue 1. 2024-06-11. PMID:38862515. vsmc-specific nf90/110 knockout in male mice decreases obviously ages-induced atherosclerotic calcification, along with the inhibitions of vsmc phenotypic changes to osteoblast-like cells, apoptosis, and matrix vesicle release. 2024-06-11 2024-06-14 mouse
Qiwei Yang, Ali Falahati, Azad Khosh, Somayeh Vafaei, Ayman Al-Hend. Targeting Bromodomain-Containing Protein 9 in Human Uterine Fibroid Cells. Reproductive sciences (Thousand Oaks, Calif.). 2024-06-10. PMID:38858328. our studies demonstrated that targeted inhibition of brd9 with its potent inhibitor tp-472 inhibited the pathogenesis of uf through increased apoptosis and proliferation arrest and decreased extracellular matrix deposition in uf cells. 2024-06-10 2024-06-14 human
Yumin Wang, Sihang Cheng, Joshua S Fleishman, Jichao Chen, Hailin Tang, Zhe-Sheng Chen, Wenkuan Chen, Mingchao Din. Targeting anoikis resistance as a strategy for cancer therapy. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. vol 75. 2024-06-08. PMID:38850692. anoikis, known as matrix detachment-induced apoptosis or detachment-induced cell death, is crucial for tissue development and homeostasis. 2024-06-08 2024-06-11 Not clear
Yumin Wang, Joshua S Fleishman, Jinhua Wang, Jichao Chen, Lianmei Zhao, Mingchao Din. Pharmacologically inducing anoikis offers novel therapeutic opportunities in hepatocellular carcinoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 176. 2024-06-06. PMID:38843588. anoikis is a matrix detachment-induced apoptosis, also known as detachment-induced cell death, and mechanistically prevents tumor cells from escaping their native extracellular matrix to metastasize to new organs. 2024-06-06 2024-06-10 Not clear
Hantao Ye, Tingwen Cai, Yang Shen, Lin Zhao, Haojie Zhang, Jianxin Yang, Feida Li, Jiaoxiang Chen, Xiaolong Shu. MST1 knockdown inhibits osteoarthritis progression through Parkin-mediated mitophagy and Nrf2/NF-κB signalling pathway. Journal of cellular and molecular medicine. vol 28. issue 11. 2024-06-06. PMID:38842136. western blot, elisa and if were used to analyse the expression of inflammation, extracellular matrix (ecm) degradation, apoptosis and mitophagy-associated proteins. 2024-06-06 2024-06-08 Not clear
Tian Mao, Junchi Fa. Myricetin Restores Autophagy to Attenuate Lumbar Intervertebral Disk Degeneration Via Negative Regulation of the JAK2/STAT3 Pathway. Biochemical genetics. 2024-06-06. PMID:38842745. the roles of myricetin in cell apoptosis, extracellular matrix (ecm) degradation, autophagy repression, and the jak2/stat3 pathway activation were examined by cell counting kit-8, flow cytometry, western blotting, real-time quantitative polymerase chain reaction, and immunofluorescence staining. 2024-06-06 2024-06-08 rat
Xuejian Dan, Xiaochuan Gu, Ying Zi, Jiahui Xu, Chenggang Wang, Chen Li, Xiao Hu, Zhourui Wu, Yan Yu, Bin M. ARRB1 inhibits extracellular matrix degradation and apoptosis of nucleus pulposus cells by promoting autophagy and attenuates intervertebral disc degeneration. Biochimica et biophysica acta. Molecular cell research. 2024-06-05. PMID:38838859. arrb1 inhibits extracellular matrix degradation and apoptosis of nucleus pulposus cells by promoting autophagy and attenuates intervertebral disc degeneration. 2024-06-05 2024-06-08 Not clear
Lars F H Theyse, Emilia M Mazu. Osteoarthritis, adipokines and the translational research potential in small animal patients. Frontiers in veterinary science. vol 11. 2024-06-04. PMID:38831954. in the early stages, oa is characterized by damage to the extracellular matrix (ecm) and apoptosis and depletion of chondrocytes. 2024-06-04 2024-06-06 human
Yi Ting Lee, Mohd Heikal Mohd Yunus, Muhammad Dain Yazid, Azizah Ugusma. Unraveling the path to osteoarthritis management: targeting chondrocyte apoptosis for therapeutic intervention. Frontiers in cell and developmental biology. vol 12. 2024-06-03. PMID:38827524. the apoptosis of chondrocytes is believed to play an important role in oa progression due to poor chondrocytes self-repair abilities to maintain the extracellular matrix (ecm). 2024-06-03 2024-06-05 Not clear
Jiali Chen, Qinghe Zeng, Xu Wang, Rui Xu, Weidong Wang, Yuliang Huang, Qi Sun, Wenhua Yuan, Pinger Wang, Di Chen, Peijian Tong, Hongting Ji. Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling. eLife. vol 13. 2024-05-31. PMID:38819423. aberrant methylation and expression of tnxb promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via akt signaling. 2024-05-31 2024-06-02 mouse
Tess Grett Mathes, Mahsa Monirizad, Menekse Ermis, Natan Roberto de Barros, Marco Rodriguez, Heinz-Bernhard Kraatz, Vadim Jucaud, Ali Khademhosseini, Natashya Falcon. Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype. Acta biomaterialia. 2024-05-27. PMID:38801867. our results demonstrated higher levels of neuroinflammation and apoptosis markers when npcs were cultured in the amyloid-like matrix compared to a natural brain matrix. 2024-05-27 2024-06-01 Not clear
Martina Tosi, Irene Coloretti, Marianna Meschiari, Sara De Biasi, Massimo Girardis, Stefano Busan. The Interplay between Antibiotics and the Host Immune Response in Sepsis: From Basic Mechanisms to Clinical Considerations: A Comprehensive Narrative Review. Antibiotics (Basel, Switzerland). vol 13. issue 5. 2024-05-26. PMID:38786135. from pre-clinical studies, antibiotics exhibit various immunomodulatory effects, including the regulation of pro-inflammatory cytokine production, interaction with toll-like receptors, modulation of the p38/pmk-1 pathway, inhibition of matrix metalloproteinases, blockade of nitric oxide synthase, and regulation of caspase-induced apoptosis. 2024-05-26 2024-05-27 Not clear
Xue-Shi DI, Jiang Chen, Xin-Ru Wang, Jun-Jie Liang, Chong-Yang Zhang, Ting Pan, Yan Meng, Jia-Jia Zhang, Zhi-Wei Feng, Wen-Ting Sun, Peng Ba. Progress of researches on mechanisms of acupuncture therapy in the treatment of lumbar disc herniation. Zhen ci yan jiu = Acupuncture research. vol 49. issue 5. 2024-05-19. PMID:38764125. in the present paper, we summarize the progress of researches on the mechanisms of acupuncture underlying improvement of symptoms of ldh in recent 10 years from 1) delaying the intervertibral disc degeneration (by down-regulating the expressions of matrix metalloproteinase [mmp]-3 and mmp-4, up-regulating the expressions of diosaccharides and polyglycoprotein, inhibiting apoptosis and promoting mitochondrial autophagy of nucleus pulposus cells, etc. 2024-05-19 2024-05-27 Not clear
Boyuan Chen, Weihao Fu, Chunyang Jie, Guoxiu Zhang, Zhen Li, Yihai Liu, Shibo Zho. GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis. Molecular medicine reports. vol 30. issue 1. 2024-05-17. PMID:38757339. the effects of gpx7 overexpression on intracellular inflammation, extracellular matrix (ecm) degradation, apoptosis and ferroptosis were then evaluated. 2024-05-17 2024-05-27 human
X Y Liao, P Liu, T F Luo, Y Li, Y Gao, F Y Pan, K C Wan. Punicalagin attenuates isoproterenol-induced myocardial infarction through nuclear factor erythroid 2-related factor 2/silent information regulator transcript-1-mediated inhibition of inflammation and cardiac stress markers in experimental animal models. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 2. 2024-05-13. PMID:38736260. additionally, pcn inhibited (p<0.01) iso-induced overexpression of oxidative stress markers (p-38, p-c-jun n-terminal kinase, and p-extracellular signal-regulated kinase 1), inflammatory markers (nuclear factor-kappa b, tumor necrosis factor-alpha, and interleukin-6), and matrix metalloproteinases and decreased the levels (p<0.01) of apoptosis proteins in the rats. 2024-05-13 2024-05-27 rat
Marlen Alexis Gonzalez-Reyna, Ricardo Aguilar-Villalva, José López, Angelina Rodríguez-Torres, Gustavo A Molina, Karla Juarez-Moreno, Rodrigo Esparza, Miriam Esteve. Nanoarchitectonics of an acetogenin-enriched nanosystem mediated by an aqueous extract of Nanotechnology. 2024-05-03. PMID:38701760. nanoarchitectonics of an acetogenin-enriched nanosystem mediated by an aqueous extract of for the first time, this study shows the nanoarchitectonic process to obtain an acetogenin-enriched nanosystem (aunps-ac) using an aqueous extract from annona cherimola mill (acm) composed of gold nanoparticles embedded in an organic matrix that acts as stabilizing agent and presents anti-inflammatory activity and cytotoxical effect against hepg2 cell line, promoting apoptosis. 2024-05-03 2024-05-06 Not clear
Bin Hu, Gongwen D. OSTF1 knockdown mitigates IL-1β-induced chondrocyte injury via inhibiting the NF-κB signaling pathway. Heliyon. vol 10. issue 9. 2024-05-03. PMID:38699012. next, the role of ostf1 in interleukin-1β (il-1β)-induced chondrocyte apoptosis, inflammation and extracellular matrix degradation was explored through loss of function assays. 2024-05-03 2024-05-05 rat
Linhe Lu, Yalan Shao, Nisha Wang, Xiang Xiong, Mengen Zhai, Jiayou Tang, Yang Liu, Jian Yang, Lifang Yan. Follistatin-like protein 1 attenuates doxorubicin-induced cardiomyopathy by inhibiting MsrB2-mediated mitophagy. Molecular and cellular biochemistry. 2024-05-02. PMID:38696001. fstl1 treatment attenuated dox-induced cardiac dysfunction, cardiac fibrosis, and cellular apoptosis by inhibiting excess mitochondrial matrix protein methionine sulfoxide reductase b2 (msrb2)-mediated mitophagy. 2024-05-02 2024-05-04 Not clear
Yuanchi Huang, Wenjie Pan, Jianbing M. SKP2-mediated ubiquitination and degradation of KLF11 promotes osteoarthritis via modulation of JMJD3/NOTCH1 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 9. 2024-05-01. PMID:38690715. skp2/jmjd3 silencing or klf11 overexpression repressed apoptosis and extracellular matrix (ecm) degradation in chondrocytes. 2024-05-01 2024-05-03 rat
Ke-Xun Yu, Wei-Jie Yuan, Hui-Zhen Wang, Yong-Xiang L. Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion. Cancer immunology, immunotherapy : CII. vol 73. issue 6. 2024-05-01. PMID:38693304. recent research evidence have shown that the extracellular matrix plays an important role in angiogenesis, cell proliferation, migration, immunosuppression, apoptosis, metabolism, and resistance to chemotherapeutic by the alterations toward both secretion and degradation. 2024-05-01 2024-05-04 Not clear