All Relations between apoptosis and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Heng Yu, Kaiye Chen, Xiang Li, Jinghao Liang, Yangcan Jin, Yingying Bao, Hao Chen, Yong Gou, Keyu Lu, Long Wu, Zhongke Li. Palmatine activation of TFEB enhances autophagy and alleviates endoplasmic reticulum stress in intervertebral disc degeneration. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 139. 2025-02-11. PMID:39933468. intervertebral disc degeneration (idd) is integral in lower back pain and involves complex pathophysiological processes, including nucleus pulposus (np) cell apoptosis and extracellular matrix (ecm) breakdown. 2025-02-11 2025-02-14 Not clear
Zaiwei Fan, Jianyuan Gao, Yikun Chen, Qirui Chen, Qingshan Peng, Jiadi Le, Yiming Li, Chunhui Chen, Haihong Jiang, Jun Tao, Yang Zho. Psoralen remodels the articular cartilage microenvironment by pharmacologically regulating the Nrf2 pathway in osteoarthritis treatment. International immunopharmacology. vol 149. 2025-02-06. PMID:39914283. osteoarthritis (oa) is a common degenerative joint disease featuring extracellular matrix degradation and apoptosis in the inflammatory microenvironment. 2025-02-06 2025-02-09 Not clear
Ashwani Kumar Gupta, Ekta Minocha, Kyle M Koss, Bilal A Naved, Luisa Safar-Boueri, Jason A Wertheim, Lorenzo Gallo. A kidney organoid-based readout to assess disease activity in primary and recurrent focal segmental glomerulosclerosis. Kidney international. 2025-02-06. PMID:39914654. the pfsgs plasma treatment induced podocytopathy, extracellular matrix protein deposition, fibrosis and apoptosis within organoids, whereas non-recurrent plasma did not affect organoid structure. 2025-02-06 2025-02-09 human
Siew Wee Chan, Camellia Ong, Wanjin Hon. The recent advances and implications in cancer therapy for the hippo pathway. Current opinion in cell biology. vol 93. 2025-02-05. PMID:39908768. these cues include cytoskeletal organization, mechanical force, cell-cell interaction, cell polarity, cell-extracellular matrix interaction to govern cell proliferation, differentiation, apoptosis, stem cell property and tissue microenvironment. 2025-02-05 2025-02-08 Not clear
Ekaterina Legchenko, Philippe Chouvarine, Klea Hysko, Fatimunnisa Qadri, Radoslaw Wesolowski, Edgar Specker, Silke Glage, Martin Meier, Katharina Schwarz, Joerg Heineke, Gerhard Pohlmann, Mehmet Ramazanoglu, Michael Bader, Georg Hansman. Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension. American journal of respiratory cell and molecular biology. 2025-02-04. PMID:39899532. rna-sequencing unraveled tphi-induced changes in pulmonary gene expression: 1) increased cell adhesion and reduced cell motility/migration; 2) suppressed extracellular matrix remodeling; 3) modulated immune response; 4) suppressed pulmonary vascular remodeling via modulating proliferation, apoptosis, and homeostasis. 2025-02-04 2025-02-06 rat
Dengbo Yao, Ming Li, Weike Zeng, Kun Wang, Zhuangyao Liao, Enming Chen, Tong Xing, Yuwei Liang, Jun Tang, Guoming Wen, Qing Ning, Yuxi Li, Lin Huan. LRP1 mitigates intervertebral disc degeneration by inhibiting endoplasmic reticulum stress through stabilizing the PPARγ. Journal of orthopaedic translation. vol 50. 2025-02-03. PMID:39895867. intervertebral disc degeneration (idd) is a significant cause of lower back pain, characterized by inflammation-mediated extracellular matrix (ecm) degradation, apoptosis, and aging of nucleus pulposus (np) cells. 2025-02-03 2025-02-05 Not clear
Zhixin Jiang, Boyang Zhang, Shichong Jia, Xiaoyong Yua. Molecular Subtype Identification and Potential Drug Prediction Based on Anoikis-Related Genes Expression in Keratoconus. Investigative ophthalmology & visual science. vol 66. issue 2. 2025-02-03. PMID:39898909. anoikis is a special apoptosis accompanied by the loss of extracellular matrix (ecm) environment and the decomposition of ecm is an important process in the occurrence of keratoconus (kc). 2025-02-03 2025-02-05 Not clear
Chen Chen, Mengyao Wang, Daoyuan Tu, Jun Cao, Chi Zhang, Dousheng Ba. Roles of anoikis in hepatocellular carcinoma: mechanisms and therapeutic potential. Medical oncology (Northwood, London, England). vol 42. issue 3. 2025-01-31. PMID:39885089. however, in advanced stages, resection alone does not sufficiently address the disease, so finding a method with a better prognosis is necessary. anoikis, known as matrix detachment-induced apoptosis or detachment-induced cell death, is crucial for tissue development and homeostasis. 2025-01-31 2025-02-02 Not clear
Chih-Chien Wang, Jeng-Wei Lu, Ya-Wun Wu, You-Hsiang Chu, Yi-Jung Ho, Feng-Cheng Liu, Yi-Jen Pen. CN7:1h Alleviates Inflammation, Apoptosis and Extracellular Matrix Degradation in Osteoarthritis by Modulating the NF-κB and mTOR Pathways. Journal of cellular and molecular medicine. vol 29. issue 3. 2025-01-28. PMID:39875323. cn7:1h alleviates inflammation, apoptosis and extracellular matrix degradation in osteoarthritis by modulating the nf-κb and mtor pathways. 2025-01-28 2025-01-31 rat
Marcin Morawski, Maciej Krasnodębski, Jakub Rochoń, Hubert Kubiszewski, Michał Marzęcki, Dominik Topyła, Kacper Murat, Mikołaj Staszewski, Jacek Szczytko, Marek Maleszewski, Michał Grą. Decellularized Liver Matrices for Expanding the Donor Pool-An Evaluation of Existing Protocols and Future Trends. Biomolecules. vol 15. issue 1. 2025-01-25. PMID:39858491. the introduction of apoptosis induction in the field of organ engineering may provide a valuable alternative to existing long perfusion protocols, which lead to significant matrix damage. 2025-01-25 2025-01-28 Not clear
Dong Zheng, Tong Chen, Kaiyuan Yang, Guangrong Yin, Yang Chen, Jianchao Gui, Chao Xu, Songwei L. Microfluidic Synthesis of miR-200c-3p Lipid Nanoparticles: Targeting ZEB2 to Alleviate Chondrocyte Damage in Osteoarthritis. International journal of nanomedicine. vol 20. 2025-01-20. PMID:39830158. chondrocyte inflammation, apoptosis, and extracellular matrix degradation accelerated oa progression. 2025-01-20 2025-01-23 Not clear
Jun Liu, Yonghua Cai, Khalil Ur Rahman, Qixiong Zhou, Guangjie Liu, Huibin Kang, Mingzhou Li, Shichao Zhang, Gang Wang, Wenfeng Feng, Xi'an Zhang, Guozhong Zhang, Ye Song, Peng L. Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats. Fluids and barriers of the CNS. vol 22. issue 1. 2025-01-16. PMID:39815354. oxidative stress and neuronal apoptosis could be an important factor leading to post-hemorrhagic consequences after germinal matrix hemorrhage (gmh). 2025-01-16 2025-01-19 human
Raquel González-Novo, Marina Armesto, África González-Murillo, Marcel Dreger, Adam F L Hurlstone, Ana Benito, Rafael Samaniego, Manuel Ramírez, Javier Redondo-Muño. Dual effect of targeting LSD1 on the invasiveness and the mechanical response of acute lymphoblastic leukemia cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 183. 2025-01-16. PMID:39818101. using a 3d matrix model, lsd1 inhibition promoted all cell invasion without significantly affecting the cell cycle progression or apoptosis under the tested conditions. 2025-01-16 2025-01-19 Not clear
Jun Liu, Yonghua Cai, Khalil Ur Rahman, Qixiong Zhou, Guangjie Liu, Huibin Kang, Mingzhou Li, Shichao Zhang, Gang Wang, Wenfeng Feng, Xi'an Zhang, Guozhong Zhang, Ye Song, Peng L. Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats. Fluids and barriers of the CNS. vol 22. issue 1. 2025-01-16. PMID:39815354. rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via erk-nnos-no pathway after germinal matrix hemorrhage in rats. 2025-01-16 2025-01-19 human
Chuan Guo, Yuheng Liu, Fei Ma, Xueyuan Xu, Weifei Zhang, Zhen Zhao, Yu Wang, Qingquan Kon. Microenvironment Remodeling Microgel Repairs Degenerated Intervertebral Disc via Programmed Delivery of MicroRNA-155. ACS applied materials & interfaces. 2025-01-13. PMID:39804788. the progression of intervertebral disc degeneration (ivdd) is associated with increased cell apoptosis and reduced extracellular matrix (ecm) production, both of which are driven by ongoing inflammation. 2025-01-13 2025-01-16 Not clear
Fu-Qin Zhu, Jia-Yi Ma, Yuan-Yuan Zhang, Yan Y. [Research progress on mechanisms and pharmacokinetics of ligustilide in treatment of locomotor system diseases]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 24. 2025-01-13. PMID:39805752. its mechanisms of action include enhancing the differentiation ability of osteoblasts(obs), inhibiting the formation ability of osteoclasts(ocs), downregulating inflammatory factors, promoting the synthesis of extracellular matrix(ecm), improving local blood supply to the femoral head, balancing lipid metabolism, inhibiting the proliferation and migration of osteosarcoma cells, inducing cell cycle arrest, enhancing glucose utilization in skeletal muscle, and regulating autophagy and apoptosis. 2025-01-13 2025-01-16 Not clear
Xiaonan Zhou, Peng Jiang, Huangqi Tan, Yanfang Wang, Lunhao Ba. KLF9-GRK5-HDAC6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis. Communications biology. vol 8. issue 1. 2025-01-09. PMID:39779910. klf9-grk5-hdac6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis. 2025-01-09 2025-01-13 rat
Xiaonan Zhou, Peng Jiang, Huangqi Tan, Yanfang Wang, Lunhao Ba. KLF9-GRK5-HDAC6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis. Communications biology. vol 8. issue 1. 2025-01-09. PMID:39779910. furthermore, knockdown of klf9 inhibited oa-related cartilage injury, as evidenced by inhibiting chondrocyte extracellular matrix (ecm) degradation, increasing chondrocyte viability, and decreasing apoptosis. 2025-01-09 2025-01-13 rat
Qiudong Geng, Weixin Wu, Meixin Yang, Fucheng Gu, Weijun Cai, Yangyi Qin, Lifang Wei, Heming Wang, Nan L. Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway. Heliyon. vol 10. issue 24. 2025-01-06. PMID:39759286. guilu erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the atf6/grp78/chop signaling pathway. 2025-01-06 2025-01-08 Not clear
Qiudong Geng, Weixin Wu, Meixin Yang, Fucheng Gu, Weijun Cai, Yangyi Qin, Lifang Wei, Heming Wang, Nan L. Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway. Heliyon. vol 10. issue 24. 2025-01-06. PMID:39759286. knee osteoarthritis (koa) is characterized by phenotypic alterations, apoptosis, and the breakdown of the extracellular matrix (ecm) in the superficial articular cartilage cells. 2025-01-06 2025-01-08 Not clear