All Relations between apoptosis and matrix compartment

Publication Sentence Publish Date Extraction Date Species
Nan Wang, Weihao Rong, Yimin Xie, Shuang Chen, Zhipeng Xi, Rongrong Den. Visualizing the bibliometrics of the inflammatory mechanisms in intervertebral disc degeneration. Experimental gerontology. 2024-02-21. PMID:38382680. the progression of ivdd is linked to structural and functional alterations in tissues, where an imbalance in the inflammatory microenvironment can induce extracellular matrix (ecm) degradation, senescence, and apoptosis. 2024-02-21 2024-02-24 Not clear
Jie Chen, Bin Zhang, Liwei Wu, Jiabin X. Ginsenoside Rg3 exhibits anti-catabolic and anti-apoptotic effects in IL-1β treated human disc nucleus pulposus cells and in a rat model of disc degeneration by inactivating the MAPK pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 1. 2024-02-19. PMID:38372089. idd is characterized by a large number of apoptosis of nucleus pulposus cells (npcs) and extracellular matrix (ecm) degradation. 2024-02-19 2024-02-21 human
Xueqiang Tao, Fen Xue, Jiayuan Xu, Wenbo Wan. Platelet-rich plasma-derived extracellular vesicles inhibit NF-κB/NLRP3 pathway-mediated pyroptosis in intervertebral disc degeneration via the MALAT1/microRNA-217/SIRT1 axis. Cellular signalling. 2024-02-19. PMID:38373669. intervertebral disc degeneration (idd) is a main contributor to lower back pain, and compression stress-induced apoptosis of nucleus pulposus (np) cells and extracellular matrix (ecm) degradation has been implicated in the idd progression. 2024-02-19 2024-02-22 mouse
Jian Wu, Chaoye Wang, Shuhui Sun, Tianmin Ren, Lijie Pan, Hongyi Liu, Simeng Hou, Shen Wu, Xuejing Yan, Jingxue Zhang, Xiaofang Zhao, Weihai Liu, Sirui Zhu, Shuwen Wei, Chi Zhang, Xu Jia, Qi Zhang, Ziyu Yu, Yehong Zhuo, Qi Zhao, Chenlong Yang, Ningli Wan. Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues. Protein & cell. 2024-02-17. PMID:38366188. our work further demonstrated that silencing the apoe gene could increase migration and reduce apoptosis by releasing the inhibition on the pi3k-akt pathway and downregulating the expression of extracellular matrix components, thereby increasing the aqueous outflow rate and maintaining intraocular pressure within the normal range. 2024-02-17 2024-02-19 monkey
Yi Sun, Yu Ren, Li-Yun Song, Yin-Ying Wang, Tian-Gang Li, Ying-Li Wu, Li Li, Zhong-Shan Yan. Targeting iron-metabolism:a potential therapeutic strategy for pulmonary fibrosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 172. 2024-02-16. PMID:38364737. dysregulation of iron can lead to iron overload, which increases the virulence of microbial colonisers and the occurrence of oxidative stress, causing alveolar epithelial cells to undergo necrosis and apoptosis, and form extracellular matrix. 2024-02-16 2024-02-19 Not clear
Yan Wu, Luxin Li, Zuojun Ning, Changrong Li, Yongkui Yin, Kaiyuan Chen, Lu Li, Fei Xu, Jie Ga. Autophagy-modulating biomaterials: multifunctional weapons to promote tissue regeneration. Cell communication and signaling : CCS. vol 22. issue 1. 2024-02-15. PMID:38360732. this involves the regulation of autophagy in diverse cell types implicated in tissue regeneration, encompassing the modulation of inflammatory responses, oxidative stress, cell differentiation, proliferation, migration, apoptosis, and extracellular matrix formation. 2024-02-15 2024-02-18 Not clear
Jie Li, Junqin Zhang, Zhaoping Chu, Hua Han, Yuan Zhan. FZD3 regulates the viability, apoptosis, and extracellular matrix degradation of vaginal wall fibroblasts in pelvic organ prolapse via the Wnt signaling pathway. Journal of biochemical and molecular toxicology. vol 38. issue 2. 2024-02-13. PMID:38348712. fzd3 regulates the viability, apoptosis, and extracellular matrix degradation of vaginal wall fibroblasts in pelvic organ prolapse via the wnt signaling pathway. 2024-02-13 2024-02-15 Not clear
Chen-Yu Li, Ru-Xin Xie, Shi-Wei Zhang, Jiao Yun, Ai Zhong, Ying Cen, Jun-Jie Che. Metabolism, fibrosis, and apoptosis: The effect of lipids and their derivatives on keloid formation. International wound journal. vol 21. issue 2. 2024-02-10. PMID:38339798. our research elucidates the pivotal roles of lipids and their derivatives in keloid development, driven by underlying mechanisms of abnormal cell proliferation, apoptosis, and extracellular matrix deposition. 2024-02-10 2024-02-12 Not clear
Dominika Domagała, Krzysztof Data, Hubert Szyller, Maryam Farzaneh, Paul Mozdziak, Sławomir Woźniak, Maciej Zabel, Piotr Dzięgiel, Bartosz Kempist. Cellular, Molecular and Clinical Aspects of Aortic Aneurysm-Vascular Physiology and Pathophysiology. Cells. vol 13. issue 3. 2024-02-09. PMID:38334666. the loss of extracellular matrix (ecm) due to cell apoptosis and phenotype switching reduces tissue density and may contribute to aaa. 2024-02-09 2024-02-11 Not clear
Shaohui Li, Yunwei Wang, Yang Chen, Hao Zhang, Peng Cao, Kuo Shen, Hao Gua. PTEN hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through Bcl-xL. Archives of biochemistry and biophysics. 2024-02-07. PMID:38325773. pten hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through bcl-xl. 2024-02-07 2024-02-10 Not clear
Shaohui Li, Yunwei Wang, Yang Chen, Hao Zhang, Peng Cao, Kuo Shen, Hao Gua. PTEN hinders the formation of scars by regulating the levels of proteins in the extracellular matrix and promoting the apoptosis of dermal fibroblasts through Bcl-xL. Archives of biochemistry and biophysics. 2024-02-07. PMID:38325773. the findings of our study provide validation for the role of pten in inhibiting the development of hypertrophic scars (hs) by modulating the expression of extracellular matrix (ecm) proteins and promoting apoptosis in hypertrophic scar fibroblasts (hsfs) via bcl-xl. 2024-02-07 2024-02-10 Not clear
Deren Liu, Wei Mei, Junfeng Kang, Taiyang Liao, Yibao Wei, Lishi Jie, Lei Shi, Peimin Wang, Jun Mao, Peng W. Casticin ameliorates osteoarthritic cartilage damage in rats through PI3K/AKT/HIF-1α signaling. Chemico-biological interactions. 2024-02-03. PMID:38309612. in vivo, cas attenuated il-1β-induced cartilage matrix degradation, apoptosis and the inflammatory response. 2024-02-03 2024-02-06 rat
Karan Vishwanath, Erica J Secor, Amanda Watkins, Heidi L Reesink, Lawrence J Bonassa. Loss of effective lubricating viscosity is the primary mechanical marker of joint inflammation in equine synovitis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024-01-30. PMID:38291343. synovitis involves the release of a wide variety of pro-inflammatory mediators in synovial fluid (sf) that damage the articular cartilage extracellular matrix and induce death and apoptosis in chondrocytes. 2024-01-30 2024-02-02 Not clear
Jinjie Zhang, Xiaowei Qin, ZhiBin Bi, Ruilong Niu, Kangkang Zhang, Xianghuang Mei, Wei Gu. Mechanism of miR-548b-5p down-regulating FZD7 to impede the migratory and invasive behavior of gastric carcinoma cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 14. 2024-01-27. PMID:38279460. wb was used to detect the satb1, as well as the expression levels of proteins involved in apoptosis, including caspase-3, bax, and bcl-2, as well as matrix metalloproteinase 2 and 9 (mmp-2 and mmp-9) in sw620 cells. 2024-01-27 2024-01-29 human
Xuezhong Wang, Xuyang Li, Jianlin Zhou, Zheng Lei, Xiaoming Yan. Fisetin suppresses chondrocyte senescence and attenuates osteoarthritis progression by targeting sirtuin 6. Chemico-biological interactions. 2024-01-26. PMID:38278314. both the administration of fst and activation of sirt6 using mdl were found to rescue cartilage erosion, decrease extracellular matrix (ecm) degradation, prevent cartilage from apoptosis, and improve detrimental senescence-related phenotype. 2024-01-26 2024-01-29 human
Qiwei Yang, Somayeh Vafaei, Ali Falahati, Azad Khosh, Maria Victoria Bariani, Mervat M Omran, Tao Bai, Hiba Siblini, Mohamed Ali, Chuan He, Thomas G Boyer, Ayman Al-Hend. Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38255982. targeted inhibition of brd9 suppressed uf tumorigenesis with increased apoptosis and cell cycle arrest, decreased cell proliferation, and extracellular matrix deposition in uf cells. 2024-01-23 2024-01-25 human
Brian D Cosgrove, Lexi R Bounds, Carson Key Taylor, Alan L Su, Anthony J Rizzo, Alejandro Barrera, Gregory E Crawford, Brenton D Hoffman, Charles A Gersbac. Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260455. these 'mechanoenhancers' could be active on either soft or stiff extracellular matrix contexts, and regulated transcription to influence critical cell functions including apoptosis, mechanotransduction, proliferation, and migration. 2024-01-23 2024-01-25 Not clear
Piotr Pawlicki, Begum Yurdakok-Dikmen, Waclaw Tworzydlo, Malgorzata Kotula-Bala. Toward understanding the role of the interstitial tissue architects: Possible functions of telocytes in the male gonad. Theriogenology. vol 217. 2024-01-19. PMID:38241912. these establish a three-dimensional network enabling the maintenance of interstitial compartment homeostasis through regulation of extracellular matrix organization and activity, structural support, paracrine and juxtracrine communication, immunomodulation, immune surveillance, cell survival, and apoptosis. 2024-01-19 2024-01-22 Not clear
Xin Jin, Qing Hu, Meiying Qin, Yitong Yin, Zhijun Xi. Balkan medical journal. 2024-01-17. PMID:38229336. apoptosis and the degradation of the extracellular matrix (ecm) in hvfs contribute to the progression of pop. 2024-01-17 2024-01-19 human
Long Fang, Zhengyu Wang, Jisong Liu, Yongjie Lin, Wei Ha. General Control Non-derepressible 2 Alleviates Cartilage Degeneration and Inhibits NLRP3 Inflammasome Activation in Osteoarthritis. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2024-01-12. PMID:38213081. similarly, we demonstrated that the upregulation of gcn2 could promote chondrocyte proliferation, suppress chondrocyte apoptosis, attenuate chondrocyte inflammation and extracellular matrix degradation, and promote chondrocyte autophagy. 2024-01-12 2024-01-14 rat