| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sita Sharan Patel, Vineet Mehta, Harish Changotra, Malairaman Udayaban. Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone. Hormones and behavior. vol 78. 2016-09-15. PMID:26631485. |
cus significantly impaired hippocampal insulin signaling, membrane translocation of glucose transporter type 4 (glut4) as well as decreased the expression of autophagy5, autophagy7, b-cell lymphoma 2 and apoptosis inhibitory protein 2. |
2016-09-15 |
2023-08-13 |
mouse |
| Yong Xu, Zhifen Liu, Xi Song, Kerang Zhang, Xingrong Li, Jianhong Li, Xu Yan, Yuan Li, Zhongchen Xie, Hui Zhan. Cerebralcare Granule® attenuates cognitive impairment in rats continuously overexpressing microRNA-30e. Molecular medicine reports. vol 12. issue 6. 2016-09-12. PMID:26498486. |
a terminal deoxynucleotidyl transferase dutp nick end labeling assay was used to detect neuronal apoptosis in the dentate gyrus of the hippocampus. |
2016-09-12 |
2023-08-13 |
rat |
| Jin Zhou, Nan Zhou, Xiao-Ning Wu, Hui-Juan Cao, Ying-Jie Sun, Tie-Zheng Zhang, Ke-Yan Chen, Dong-Mei Y. Role of the Toll‑like receptor 3 signaling pathway in the neuroprotective effect of sevoflurane pre‑conditioning during cardiopulmonary bypass in rats. Molecular medicine reports. vol 12. issue 6. 2016-09-09. PMID:26460219. |
the right hippocampus was assessed for neuronal apoptosis by terminal deoxynucleotidyl transferase dutp nick end labeling assay. |
2016-09-09 |
2023-08-13 |
rat |
| Jin Zhou, Nan Zhou, Xiao-Ning Wu, Hui-Juan Cao, Ying-Jie Sun, Tie-Zheng Zhang, Ke-Yan Chen, Dong-Mei Y. Role of the Toll‑like receptor 3 signaling pathway in the neuroprotective effect of sevoflurane pre‑conditioning during cardiopulmonary bypass in rats. Molecular medicine reports. vol 12. issue 6. 2016-09-09. PMID:26460219. |
the number of apoptotic hippocampal neurons, although being generally low, was significantly increased in the c group compared with that in the h group (p<0.05), while apoptosis was significantly attenuated by sevoflurane‑pre‑treatment (p<0.05). |
2016-09-09 |
2023-08-13 |
rat |
| Saba Shahin, Somanshu Banerjee, Surya Pal Singh, Chandra Mohini Chaturved. 2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism. Toxicological sciences : an official journal of the Society of Toxicology. vol 148. issue 2. 2016-09-08. PMID:26396154. |
2.45 ghz microwave radiation impairs learning and spatial memory via oxidative/nitrosative stress induced p53-dependent/independent hippocampal apoptosis: molecular basis and underlying mechanism. |
2016-09-08 |
2023-08-13 |
mouse |
| Saba Shahin, Somanshu Banerjee, Surya Pal Singh, Chandra Mohini Chaturved. 2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism. Toxicological sciences : an official journal of the Society of Toxicology. vol 148. issue 2. 2016-09-08. PMID:26396154. |
we observed that, short-term as well as long-term 2.45 ghz mw radiation exposure increases the oxidative/nitrosative stress leading to enhanced apoptosis in hippocampal subfield neuronal and nonneuronal cells. |
2016-09-08 |
2023-08-13 |
mouse |
| Saba Shahin, Somanshu Banerjee, Surya Pal Singh, Chandra Mohini Chaturved. 2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism. Toxicological sciences : an official journal of the Society of Toxicology. vol 148. issue 2. 2016-09-08. PMID:26396154. |
these findings led us to conclude that exposure to cw mw radiation leads to oxidative/nitrosative stress induced p53-dependent/independent activation of hippocampal neuronal and nonneuronal apoptosis associated with spatial memory loss. |
2016-09-08 |
2023-08-13 |
mouse |
| Majid Motaghinejad, Morteza Karimian, Ozra Motaghinejad, Behnaz Shabab, Iraj Yazdani, Sulail Fatim. Protective effects of various dosage of Curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus. Pharmacological reports : PR. vol 67. issue 2. 2016-09-06. PMID:25712644. |
protective effects of various dosage of curcumin against morphine induced apoptosis and oxidative stress in rat isolated hippocampus. |
2016-09-06 |
2023-08-13 |
rat |
| Dinesh Thotala, Rowan M Karvas, John A Engelbach, Joel R Garbow, Andrew N Hallahan, Todd A DeWees, Andrei Laszlo, Dennis E Hallaha. Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells. Oncotarget. vol 6. issue 33. 2016-08-30. PMID:26413814. |
cranial irradiation causes apoptosis in the subgranular zone of the hippocampus leading to cognitive deficits. |
2016-08-30 |
2023-08-13 |
mouse |
| Fatemeh Zare Mehrjerdi, Nahid Aboutaleb, Hamidreza Pazoki-Toroudi, Mansoureh Soleimani, Marjan Ajami, Mehdi Khaksari, Fatemeh Safari, Rouhollah Habibe. The Protective Effect of Remote Renal Preconditioning Against Hippocampal Ischemia Reperfusion Injury: Role of KATP Channels. Journal of molecular neuroscience : MN. vol 57. issue 4. 2016-08-24. PMID:26254913. |
katp channels blocking with 5hd and gli markedly increased apoptosis in hippocampal cells in ripc group (p < 0.001). |
2016-08-24 |
2023-08-13 |
cat |
| Li Liu, Chang-jun Li, Yun Lu, Xian-gang Zong, Chao Luo, Jun Sun, Lian-jun Gu. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Scientific reports. vol 5. 2016-08-19. PMID:26412641. |
however, during chronic cerebral hypoperfusion, the changes of autophagy in the hippocampal ca1 area, the correlation between gaba receptors and autophagy, and their influences on hippocampal neuronal apoptosis have not been well established. |
2016-08-19 |
2023-08-13 |
rat |
| Li Liu, Chang-jun Li, Yun Lu, Xian-gang Zong, Chao Luo, Jun Sun, Lian-jun Gu. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion. Scientific reports. vol 5. 2016-08-19. PMID:26412641. |
here, we found that chronic cerebral hypoperfusion resulted in rat hippocampal atrophy, neuronal apoptosis, enhancement and redistribution of autophagy, down-regulation of bcl-2/bax ratio, elevation of cleaved caspase-3 levels, reduction of surface expression of gabaa receptor α1 subunit and an increase in surface and mitochondrial expression of connexin 43 (cx43) and cx36. |
2016-08-19 |
2023-08-13 |
rat |
| Zhi-wei Yang, Fei Wu, Sheng-Li Zhan. Effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of BDNF,TRPC3 and apoptosis. Die Pharmazie. vol 71. issue 6. 2016-08-17. PMID:27455554. |
effects of ganoderic acids on epileptiform discharge hippocampal neurons: insights from alterations of bdnf,trpc3 and apoptosis. |
2016-08-17 |
2023-08-13 |
rat |
| Jing Wang, Hong Ming, Rui Chen, Jing-Mei Ju, Wan-da Peng, Guo-Xing Zhang, Chun-Feng Li. CIH-induced neurocognitive impairments are associated with hippocampal Ca(2+) overload, apoptosis, and dephosphorylation of ERK1/2 and CREB that are mediated by overactivation of NMDARs. Brain research. vol 1625. 2016-08-15. PMID:26301823. |
cih-induced neurocognitive impairments are associated with hippocampal ca(2+) overload, apoptosis, and dephosphorylation of erk1/2 and creb that are mediated by overactivation of nmdars. |
2016-08-15 |
2023-08-13 |
mouse |
| Na Lin, Liu-Lin Xiong, Rong-Ping Zhang, Hong Zheng, Lei Wang, Zhong-Yi Qian, Piao Zhang, Zhi-Wei Chen, Fa-Bao Gao, Ting-Hua Wan. Erratum to: Injection of Aβ1-40 into hippocampus induced cognitive lesion associated with neuronal apoptosis and multiple gene expressions in the tree shrew. Apoptosis : an international journal on programmed cell death. vol 21. issue 5. 2016-08-15. PMID:27055829. |
erratum to: injection of aβ1-40 into hippocampus induced cognitive lesion associated with neuronal apoptosis and multiple gene expressions in the tree shrew. |
2016-08-15 |
2023-08-13 |
Not clear |
| Qing Zhu, Xu Song, Jing Zhou, Yixin Wang, Jianxun Xia, Wenyi Qian, Jingying Zhu, Rong Gao, Jun Wang, Hang Xia. Target of HIV-1 Envelope Glycoprotein gp120-Induced Hippocampal Neuron Damage: Role of Voltage-Gated K(+) Channel Kv2.1. Viral immunology. vol 28. issue 9. 2016-08-11. PMID:26393286. |
moreover, p38 mapk was demonstrated to participate in gp120-induced hippocampal neural damage, since p38 mapk antagonist (sb203580) partially abrogated gp120-induced kv2.1 upregulation and neural apoptosis. |
2016-08-11 |
2023-08-13 |
human |
| Qing Zhu, Xu Song, Jing Zhou, Yixin Wang, Jianxun Xia, Wenyi Qian, Jingying Zhu, Rong Gao, Jun Wang, Hang Xia. Target of HIV-1 Envelope Glycoprotein gp120-Induced Hippocampal Neuron Damage: Role of Voltage-Gated K(+) Channel Kv2.1. Viral immunology. vol 28. issue 9. 2016-08-11. PMID:26393286. |
taken together, these results suggest that gp120 induces hippocampal neuron apoptosis by enhancement of the ik, which might be associated with increased kv2.1 expression via the p38 mapk pathway. |
2016-08-11 |
2023-08-13 |
human |
| Xin Fu, QiuHong Wang, ZhiBin Wang, HaiXue Kuang, Pinghui Jian. Danggui-Shaoyao-San: New Hope for Alzheimer's Disease. Aging and disease. vol 7. issue 4. 2016-08-05. PMID:27493835. |
recent studies show that dss has an effect on free radical-mediated neurological diseases and exhibits anti-inflammatory and antioxidant activities and reduces cell apoptosis in the hippocampus. |
2016-08-05 |
2023-08-13 |
Not clear |
| Diana Yi Zhao, Keith M Jacobs, Dennis E Hallahan, Dinesh Thotal. Silencing Egr1 Attenuates Radiation-Induced Apoptosis in Normal Tissues while Killing Cancer Cells and Delaying Tumor Growth. Molecular cancer therapeutics. vol 14. issue 10. 2016-08-01. PMID:26206332. |
apoptosis is a key element of the radiation response in normal tissues like the hippocampus and small intestine, resulting in neurocognitive disorders and intestinal malabsorption. |
2016-08-01 |
2023-08-13 |
mouse |
| Diana Yi Zhao, Keith M Jacobs, Dennis E Hallahan, Dinesh Thotal. Silencing Egr1 Attenuates Radiation-Induced Apoptosis in Normal Tissues while Killing Cancer Cells and Delaying Tumor Growth. Molecular cancer therapeutics. vol 14. issue 10. 2016-08-01. PMID:26206332. |
we demonstrated that egr1-null mice had less apoptosis in the hippocampus and intestine following irradiation as compared with their wild-type littermates. |
2016-08-01 |
2023-08-13 |
mouse |