| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Morgan, O Dolp, C W Reute. Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling. Blood. vol 97. issue 6. 2001-04-26. PMID:11238126. |
in this study, the activation of the ras-to-mapk cascade in 14 aml and 5 chronic myeloid leukemia (cml) cell lines is examined and correlated with the effects of a panel of 9 ras signaling inhibitors on cell viability, colony formation, cell-cycle progression, and induction of apoptosis. |
2001-04-26 |
2023-08-12 |
Not clear |
| Y Mi, L Wang, S Bia. [Effect of WT1 gene expression on cell growth and proliferation in myeloid leukemia cell lines]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 19. issue 12. 2001-04-26. PMID:11263329. |
to explore the effect of wt1 antisense oligonucleotide(as-oligo) on cell proliferation and apoptosis in myeloid leukemia cell lines. |
2001-04-26 |
2023-08-12 |
Not clear |
| Y C Fu, X P Jin, S M We. The effects on cell growth of tea polyphenols acting as a strong anti-peroxidatant and an inhibitor of apoptosis in primary cultured rat skin cells. Biomedical and environmental sciences : BES. vol 13. issue 3. 2001-04-19. PMID:11198218. |
the effects on cell growth of tea polyphenols acting as a strong anti-peroxidatant and an inhibitor of apoptosis in primary cultured rat skin cells. |
2001-04-19 |
2023-08-12 |
human |
| T Ohtsubo, H Igawa, T Saito, H Matsumoto, H J Park, C W Song, E Kano, H Sait. Acidic environment modifies heat- or radiation-induced apoptosis in human maxillary cancer cells. International journal of radiation oncology, biology, physics. vol 49. issue 5. 2001-04-19. PMID:11286847. |
the effects of hyperthermia or irradiation on cell killing and induction of apoptosis were evaluated using human maxillary carcinoma imc-3 cells and low ph (ph 6.8) adapted cells (imc-3-ph). |
2001-04-19 |
2023-08-12 |
human |
| V Milovic, I C Teller, L Turchanowa, W F Caspary, J Stei. Effect of structural analogues of propionate and butyrate on colon cancer cell growth. International journal of colorectal disease. vol 15. issue 5-6. 2001-04-05. PMID:11151428. |
the aim of this study was to evaluate the effects of natural short-chain fatty acids (butyrate, propionate, valerate, acetate) and structural analogues of butyrate and propionate on cell growth and apoptosis in three human colonic adenocarcinoma cell lines (ht-29, colo-320, and sw-948). |
2001-04-05 |
2023-08-12 |
human |
| Z Zhu, W Jiang, H E Ganther, C Ip, H J Thompso. Activity of Se-allylselenocysteine in the presence of methionine gamma-lyase on cell growth, DNA integrity, apoptosis, and cell-cycle regulatory molecules. Molecular carcinogenesis. vol 29. issue 4. 2001-03-29. PMID:11170256. |
activity of se-allylselenocysteine in the presence of methionine gamma-lyase on cell growth, dna integrity, apoptosis, and cell-cycle regulatory molecules. |
2001-03-29 |
2023-08-12 |
Not clear |
| M N Rutherford, G R Bayly, B P Matthews, T Okuda, W M Dinjens, H Kondoh, D P LeBru. The leukemogenic transcription factor E2a-Pbx1 induces expression of the putative N-myc and p53 target gene NDRG1 in Ba/F3 cells. Leukemia. vol 15. issue 3. 2001-03-29. PMID:11237058. |
we show that forced expression of e2a-pbx1 induces apoptosis in ba/f3 cells without apparent effects on cell cycle progression. |
2001-03-29 |
2023-08-12 |
Not clear |
| J J Jimenez, W Jy, L M Mauro, L L Horstman, Y S Ah. Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. British journal of haematology. vol 112. issue 1. 2001-03-15. PMID:11167788. |
the effect of ttp plasma on cell viability was similar to that of tnf-alpha, implying that it induced activation rather than apoptosis. |
2001-03-15 |
2023-08-12 |
Not clear |
| A V Bazarov, S Adachi, S F Li, M K Mateyak, S Wei, J M Sediv. A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation. Cancer research. vol 61. issue 3. 2001-03-15. PMID:11221849. |
a modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to ras and raf transformation. |
2001-03-15 |
2023-08-12 |
human |
| H Kuroda, M Mandai, I Konishi, Y Tsuruta, T Kusakari, M Kariya, S Fuji. Human ovarian surface epithelial (OSE) cells express LH/hCG receptors, and hCG inhibits apoptosis of OSE cells via up-regulation of insulin-like growth factor-1. International journal of cancer. vol 91. issue 3. 2001-03-08. PMID:11169952. |
to address this issue, we examined the expression of lh/hcg receptors and the influence of hcg on cell proliferation and on the apoptosis of cultured human ose cells. |
2001-03-08 |
2023-08-12 |
human |
| A Sieradzki, A Skoczyńska, R Andrzeja. [Effect of arsenic and its compounds on the circulatory system]. Medycyna pracy. vol 51. issue 5. 2001-03-01. PMID:11199178. |
the present review is focused on the confirmed and potential mechanisms of arsenic effect on the function and structure of vascular endothelium (nitric oxide, peroxynitrite), its role in stimulating the oxidative species formation (hydroxyperoxide, superoxide and lipid peroxide formation), as well as in decreasing the antioxidative response (enzymes: superoxide dysmutase, catalase, glutation peroxidase), its cytotoxic effects, including immunotoxic properties, arsenic action in the signal transduction pathways network (kinases and dna transcription factors), impact on cell proliferation, differentiation and apoptosis, not to mention its interference with dna synthesis and repair processes. |
2001-03-01 |
2023-08-12 |
Not clear |
| F J Wan. Analysis of downstream effectors of p53 on cell growth arrest and apoptosis induced by a temperature-sensitive Val138 mutant. Journal of medical and dental sciences. vol 45. issue 2. 2001-02-08. PMID:11186200. |
analysis of downstream effectors of p53 on cell growth arrest and apoptosis induced by a temperature-sensitive val138 mutant. |
2001-02-08 |
2023-08-12 |
human |
| L B Chiarini, R Linde. Tissue biology of apoptosis. Ref-1 and cell differentiation in the developing retina. Annals of the New York Academy of Sciences. vol 926. 2001-02-01. PMID:11193042. |
the sensitivity to apoptosis in developing nervous tissue is strongly dependent on cell interactions taking place within a highly structured environment, composed of various cell types at distinct stages of differentiation. |
2001-02-01 |
2023-08-12 |
Not clear |
| C M Perks, C McCaig, J M Holl. Differential insulin-like growth factor (IGF)-independent interactions of IGF binding protein-3 and IGF binding protein-5 on apoptosis in human breast cancer cells. Involvement of the mitochondria. Journal of cellular biochemistry. vol 80. issue 2. 2001-01-26. PMID:11074596. |
we have demonstrated previously in hs578t cells that insulin-like growth factor binding protein (igfbp)-3 can significantly accentuate ceramide (c2)-induced apoptosis, but has no effect on cell death induced by integrin detachment [using an arginine-glycine-aspartic acid (rgd)-containing peptide]. |
2001-01-26 |
2023-08-12 |
human |
| B Bölling, J Fandrey, P J Frosch, H Acke. VEGF production, cell proliferation and apoptosis of human IGR 1 melanoma cells under nIFN-alpha/beta and rIFN-gamma treatment. Experimental dermatology. vol 9. issue 5. 2001-01-25. PMID:11016853. |
the effect of natural and recombinant interferons (nifn, rifn) on cell growth, apoptosis and the production of vascular endothelial growth factor (vegf) was investigated in the human melanoma cell line igr 1. |
2001-01-25 |
2023-08-12 |
human |
| S F Walk, M Alexander, B Maier, M L Hammarskjold, D M Rekosh, K S Ravichandra. Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation. Journal of virology. vol 75. issue 2. 2001-01-25. PMID:11134296. |
this has been attributed to effects of nef on cell proliferation and apoptosis. |
2001-01-25 |
2023-08-12 |
human |
| S Hashimoto, A Ishisaki, K Yamato, K Aiko, T Amagasa, T Nishihar. Intracellular apoptosis-inducing factor is induced by a vacuolar type H+-ATPase inhibitor in B lineage cells. Journal of cellular physiology. vol 186. issue 1. 2001-01-25. PMID:11147815. |
while activin a also induced apoptosis in hs-72 cells, the cytosol from activin a-treated hs-72 cells had no effect on cell viability. |
2001-01-25 |
2023-08-12 |
human |
| G Rosenberger, G Fuhrmann, M Grusch, S Fassl, H L Elford, K Smid, G J Peters, T Szekeres, G Krupitz. The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells. Life sciences. vol 67. issue 26. 2001-01-25. PMID:11191620. |
since the mode of action of trimidox on cell fate has not been investigated so far, we addressed this unresolved item and find that this polyhydroxybenzoic acid derivative induces apoptosis of n.1 human ovarian carcinoma cells when tested in growth factor deprived medium. |
2001-01-25 |
2023-08-12 |
mouse |
| M T Santini, G Rainaldi, P L Indovin. Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids. Critical reviews in oncology/hematology. vol 36. issue 2-3. 2001-01-09. PMID:11033298. |
in the last few years, it has become increasingly apparent that cell survival and death, especially apoptosis, strongly depend on cell adhesion and the extracellular matrix. |
2001-01-09 |
2023-08-12 |
Not clear |
| K Honoki, T Tsujiuchi, M Tsutsumi, A Kido, T Morishita, M Yoshimoto, Y Miyauchi, Y Mii, S Tamai, Y Konish. Possible involvement of bcl-2 suppression in wild-type p53 gene-dependent cell growth repression in rat osteosarcoma cells. Toxicologic pathology. vol 28. issue 4. 2001-01-08. PMID:10930045. |
in this study, we applied wild-type p53 gene transfer to the rat osteosarcoma cells by lipofection to investigate the effects on cell growth, expression of genes such as waf1/p21, bcl-2, and bax, and nucleosomal dna fragmentation due to apoptosis. |
2001-01-08 |
2023-08-12 |
human |