| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Dikranian, M J Ishimaru, T Tenkova, J Labruyere, Y Q Qin, C Ikonomidou, J W Olne. Apoptosis in the in vivo mammalian forebrain. Neurobiology of disease. vol 8. issue 3. 2001-08-16. PMID:11447994. |
however, contemporary neurobiologists typically rely on cell culture models for studying neuronal apoptosis, and these models are rarely validated ultrastructurally; rather they are assumed to be appropriate models based on unvalidated biochemical tests for apoptosis. |
2001-08-16 |
2023-08-12 |
human |
| Y M Mu, T Yanase, Y Nishi, A Tanaka, M Saito, C H Jin, C Mukasa, T Okabe, M Nomura, K Goto, H Nawat. Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells. Endocrinology. vol 142. issue 8. 2001-08-16. PMID:11459807. |
the suppressive effect of saturated ffas on cell survival was caused by apoptosis, as evidenced by dna ladder formation and annexin v-egfp/propidium iodide staining of the cells. |
2001-08-16 |
2023-08-12 |
human |
| F Turturro, A Y Frist, M D Arnold, A Pal, G A Cook, P Set. Comparison of the effects of recombinant adenovirus-mediated expression of wild-type p53 and p27Kip1 on cell cycle and apoptosis in SUDHL-1 cells derived from anaplastic large cell lymphoma. Leukemia. vol 15. issue 8. 2001-08-16. PMID:11480564. |
comparison of the effects of recombinant adenovirus-mediated expression of wild-type p53 and p27kip1 on cell cycle and apoptosis in sudhl-1 cells derived from anaplastic large cell lymphoma. |
2001-08-16 |
2023-08-12 |
human |
| F Turturro, A Y Frist, M D Arnold, A Pal, G A Cook, P Set. Comparison of the effects of recombinant adenovirus-mediated expression of wild-type p53 and p27Kip1 on cell cycle and apoptosis in SUDHL-1 cells derived from anaplastic large cell lymphoma. Leukemia. vol 15. issue 8. 2001-08-16. PMID:11480564. |
recombinant adenoviruses expressing wild-type p53 (adwtp53) and p27kip1 (adp27) were used to compare the effects on cell cycle and apoptosis in sudhl-1 cells derived from human anaplastic large cell lymphoma. |
2001-08-16 |
2023-08-12 |
human |
| J L Clifford, A L Sabichi, C Zou, X Yang, V E Steele, G J Kelloff, R Lotan, S M Lippma. Effects of novel phenylretinamides on cell growth and apoptosis in bladder cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. vol 10. issue 4. 2001-08-09. PMID:11319181. |
effects of novel phenylretinamides on cell growth and apoptosis in bladder cancer. |
2001-08-09 |
2023-08-12 |
human |
| J Flygare, S Fält, J Ottervald, J Castro, Dackland AL, D Hellgren, A Wennbor. Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis. Experimental cell research. vol 268. issue 1. 2001-08-09. PMID:11461118. |
effects of hsrad51 overexpression on cell proliferation, cell cycle progression, and apoptosis. |
2001-08-09 |
2023-08-12 |
human |
| J Flygare, S Fält, J Ottervald, J Castro, Dackland AL, D Hellgren, A Wennbor. Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis. Experimental cell research. vol 268. issue 1. 2001-08-09. PMID:11461118. |
in order to study the effects of acute hsrad51 ectopic overexpression on cell proliferation, cell cycle progression, and apoptosis, we generated clones of the human fibrosarcoma cell line ht1080 carrying a hsrad51 transgene under a repressible promoter. |
2001-08-09 |
2023-08-12 |
human |
| F Duquesne, M Florent, G Roué, X Troussard, B Sol. Ectopic expression of cyclin D1 impairs the proliferation and enhances the apoptosis of a murine lymphoid cell line. Cell death and differentiation. vol 8. issue 1. 2001-08-02. PMID:11313703. |
the over-expression of cyclin d1 had the same effects on cell proliferation but also led ultimately to cell death by apoptosis. |
2001-08-02 |
2023-08-12 |
Not clear |
| S De Flora, A Izzotti, F D'Agostini, R M Balansk. Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points. Carcinogenesis. vol 22. issue 7. 2001-08-02. PMID:11408342. |
n-acetylcysteine has an impressive array of mechanisms and protective effects towards dna damage and carcinogenesis, which are related to its nucleophilicity, antioxidant activity, modulation of metabolism, effects in mitochondria, decrease of the biologically effective dose of carcinogens, modulation of dna repair, inhibition of genotoxicity and cell transformation, modulation of gene expression and signal transduction pathways, regulation of cell survival and apoptosis, anti-inflammatory activity, anti-angiogenetic activity, immunological effects, inhibition of progression to malignancy, influence on cell cycle progression, inhibition of pre-neoplastic and neoplastic lesions, inhibition of invasion and metastasis, and protection towards adverse effects of other chemopreventive agents or chemotherapeutical agents. |
2001-08-02 |
2023-08-12 |
mouse |
| S K Tahir, E K Han, B Credo, H S Jae, J A Pietenpol, C D Scatena, J R Wu-Wong, D Frost, H Sham, S H Rosenberg, S C N. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors. Cancer research. vol 61. issue 14. 2001-08-02. PMID:11454695. |
the effect of a-204197 on cell growth was associated with cell cycle arrest in g2-m, increased phosphorylation of select g2-m checkpoint proteins, and apoptosis. |
2001-08-02 |
2023-08-12 |
Not clear |
| Z Darzynkiewicz, E Bedner, P Smolewsk. Flow cytometry in analysis of cell cycle and apoptosis. Seminars in hematology. vol 38. issue 2. 2001-07-26. PMID:11309699. |
for the identification of apoptotic cells and discrimination between apoptosis and necrosis, flow cytometry techniques are applied to evaluate for changes in cell morphology, the presence of phosphatidylserine on cell surface, collapse of mitochondrial transmembrane potential, dna fragmentation, and evidence of caspase activation. |
2001-07-26 |
2023-08-12 |
Not clear |
| T Ohtsubo, H Igawa, T Saito, H Matsumoto, H Park, C W Song, E Kano, H Sait. Enhancement of cell killing by induction of apoptosis after treatment with mild hyperthermia at 42 degrees C and cisplatin. Radiation research. vol 156. issue 1. 2001-07-26. PMID:11418078. |
we examined the interactive effects of cisplatin (1.0 microg/ml) combined with hyperthermia on cell killing and on the induction of apoptosis in imc-3 human maxillary carcinoma cells. |
2001-07-26 |
2023-08-12 |
human |
| S M Sebti, A D Hamilto. Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies. Oncogene. vol 19. issue 56. 2001-07-26. PMID:11426643. |
among the issues that will be addressed are: evidence for and against inhibition of the prenylation of ras and rhob proteins in the mechanism of action of ftis; implications of the alternative prenylation of k-ras by geranylgeranyl-transferase i (when ftase is inhibited) in cancer therapy; ggtase i inhibitors (ggtis) as antitumor agents; effects of ftis and ggtis on cell cycle machinery and progression and potential mechanisms by which ftis and ggtis induce apoptosis in human cancer cells. |
2001-07-26 |
2023-08-12 |
human |
| G Denecker, W Declercq, C A Geuijen, A Boland, R Benabdillah, M van Gurp, M P Sory, P Vandenabeele, G R Corneli. Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of bid. The Journal of biological chemistry. vol 276. issue 23. 2001-07-12. PMID:11279213. |
this finding supports the idea that yopp/j induces apoptosis by directly acting on cell death pathways, rather than being the mere consequence of gene induction inhibition in combination with microbial stimulation of the macrophage. |
2001-07-12 |
2023-08-12 |
Not clear |
| L Bolduc, B Labrecque, M Cordeau, M Blanchette, B Chabo. Dimethyl sulfoxide affects the selection of splice sites. The Journal of biological chemistry. vol 276. issue 20. 2001-07-05. PMID:11278983. |
the direct impact of me2so on alternative splicing may explain, at least in part, the different and sometimes opposite effects of me2so on cell differentiation and apoptosis. |
2001-07-05 |
2023-08-12 |
Not clear |
| J M Olson, A Asakura, L Snider, R Hawkes, A Strand, J Stoeck, A Hallahan, J Pritchard, S J Tapscot. NeuroD2 is necessary for development and survival of central nervous system neurons. Developmental biology. vol 234. issue 1. 2001-06-28. PMID:11356028. |
decreased levels of bdnf and higher rates of apoptosis in cerebellar granule cells of neurod2(-/-) mice indicate that neurod2 is necessary for the survival of specific populations of central nervous system neurons in addition to its known effects on cell cycle regulation and neuronal differentiation. |
2001-06-28 |
2023-08-12 |
mouse |
| E Block, M Birringer, W Jiang, T Nakahodo, H J Thompson, P J Toscano, H Uzar, X Zhang, Z Zh. Allium chemistry: synthesis, natural occurrence, biological activity, and chemistry of Se-alk(en)ylselenocysteines and their gamma-glutamyl derivatives and oxidation products. Journal of agricultural and food chemistry. vol 49. issue 1. 2001-06-21. PMID:11305255. |
three homologues of the potent cancer chemoprevention agents 6a and 6c, namely 6d-f, were evaluated for effects on cell growth, induction of apoptosis, and dna-damaging activity using two murine mammary epithelial cell lines. |
2001-06-21 |
2023-08-12 |
Not clear |
| S Moalic, B Liagre, J C Le Bail, J L Beneytou. Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor. International journal of oncology. vol 18. issue 3. 2001-05-31. PMID:11179483. |
we demonstrate a link between the effects of 10 and 100 microm ns-398 on cell apoptosis, pge2 release, and expression of cox-2 in 1547 cells undergoing apoptosis. |
2001-05-31 |
2023-08-12 |
human |
| W Zoli, L Ricotti, A Tesei, F Barzanti, D Amador. In vitro preclinical models for a rational design of chemotherapy combinations in human tumors. Critical reviews in oncology/hematology. vol 37. issue 1. 2001-05-24. PMID:11164721. |
increased knowledge of the cellular targets of traditional and new drugs and the development of new technologies have resulted in a new role for the in vitro tests which are no longer used only to evaluate the cytotoxic effects of drugs, but also to investigate the interference on cell cycle, induction of apoptosis and molecular or biochemical interactions. |
2001-05-24 |
2023-08-12 |
human |
| M J Ruiz Gómez, L De la Peña, J M Pastor, M Martínez Morillo, L Gi. 25 Hz electromagnetic field exposure has no effect on cell cycle distribution and apoptosis in U-937 and HCA-2/1cch cells. Bioelectrochemistry (Amsterdam, Netherlands). vol 53. issue 1. 2001-05-10. PMID:11206921. |
25 hz electromagnetic field exposure has no effect on cell cycle distribution and apoptosis in u-937 and hca-2/1cch cells. |
2001-05-10 |
2023-08-12 |
human |