| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Larry A Feig, Rachel J Buchsbau. Cell signaling: life or death decisions of ras proteins. Current biology : CB. vol 12. issue 7. 2002-08-27. PMID:11937045. |
the discovery of a new downstream target for the ras gtpases - a nore1-mst1 protein complex - reveals a mechanism by which ras can promote apoptosis, and suggests that the influence of ras on cell survival or death depends upon the relative level of activation of its various target proteins. |
2002-08-27 |
2023-08-12 |
Not clear |
| Francisco Leira, Ana G Cabado, Mercedes R Vieytes, Yolanda Roman, Amparo Alfonso, Luis M Botana, Takeshi Yasumoto, Claudia Malaguti, Gian P Rossin. Characterization of F-actin depolymerization as a major toxic event induced by pectenotoxin-6 in neuroblastoma cells. Biochemical pharmacology. vol 63. issue 11. 2002-08-13. PMID:12093474. |
in addition, no effect on cell attachment or apoptosis induction was observed at micromolar concentrations of pectenotoxin-6. |
2002-08-13 |
2023-08-12 |
human |
| Nigel E A Crompton, Yu-Quan Shi, Frederich Wuergler, Hans Blattman. A single low dose of X-rays induces high frequencies of genetic instability (aneuploidy) and heritable damage (apoptosis), dependent on cell type and p53 status. Mutation research. vol 517. issue 1-2. 2002-08-05. PMID:12034319. |
a single low dose of x-rays induces high frequencies of genetic instability (aneuploidy) and heritable damage (apoptosis), dependent on cell type and p53 status. |
2002-08-05 |
2023-08-12 |
human |
| Mary Jane Elliott, Michael R Farmer, Cesar Atienza, Ariel Stilwell, Yan Bin Dong, Hai Liang Yang, Sandra L Wong, Kelly M McMaster. E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 23. issue 2. 2002-08-05. PMID:12065845. |
cotreatment of the cells with e2f-1 virus and roscovitine (ros) or etoposide resulted in an additive effect on cell growth inhibition and induction of apoptosis. |
2002-08-05 |
2023-08-12 |
human |
| Marisa Belicchi Ferrari, Franco Bisceglie, Giovanna Gasparri Fava, Giorgio Pelosi, Pieralberto Tarasconi, Roberto Albertini, Silvana Pinell. Synthesis, characterization and biological activity of two new polymeric copper(II) complexes with alpha-ketoglutaric acid thiosemicarbazone. Journal of inorganic biochemistry. vol 89. issue 1-2. 2002-07-31. PMID:11931961. |
regarding the human cell lines, both complexes show proliferation inhibition through an apoptosis mechanism on cell line u937, while they have no effects on the k562 line. |
2002-07-31 |
2023-08-12 |
human |
| C M Perks, C McCaig, J B Clarke, D R Clemmons, J M P Holl. A non-IGF binding mutant of IGFBP-3 modulates cell function in breast epithelial cells. Biochemical and biophysical research communications. vol 294. issue 5. 2002-07-30. PMID:12074574. |
we demonstrated previously that igfbp-3 alone had no effect on cell death, but dramatically modulated apoptosis in hs578t igf non-responsive cells. |
2002-07-30 |
2023-08-12 |
Not clear |
| C M Perks, C McCaig, J B Clarke, D R Clemmons, J M P Holl. Effects of a non-IGF binding mutant of IGFBP-5 on cell death in human breast cancer cells. Biochemical and biophysical research communications. vol 294. issue 5. 2002-07-30. PMID:12074575. |
we have demonstrated previously that igfbp-5 alone had no effect on cell death but modulated ceramide-induced apoptosis in hs578t igf non-responsive cells. |
2002-07-30 |
2023-08-12 |
human |
| C M Perks, C McCaig, J B Clarke, D R Clemmons, J M P Holl. Effects of a non-IGF binding mutant of IGFBP-5 on cell death in human breast cancer cells. Biochemical and biophysical research communications. vol 294. issue 5. 2002-07-30. PMID:12074575. |
in hs578t cells, non-glycosylated, glycosylated or mutant igfbp-5 alone each had no effect on cell death, whereas all forms inhibited ceramide-induced apoptosis. |
2002-07-30 |
2023-08-12 |
human |
| Patrizia Russo, Davide Malacarne, Carla Falugi, Sonya Trombino, Patrick M O'Conno. RPR-115135, a farnesyltransferase inhibitor, increases 5-FU- cytotoxicity in ten human colon cancer cell lines: role of p53. International journal of cancer. vol 100. issue 3. 2002-07-30. PMID:12115540. |
in the mutated cell lines no major alterations on cell cycle arrest phenotype and no induction of apoptosis was observed. |
2002-07-30 |
2023-08-12 |
human |
| Motoyuki Otsuka, Naoya Kato, Hiroyoshi Taniguchi, Hideo Yoshida, Tadashi Goto, Yasushi Shiratori, Masao Omat. Hepatitis C virus core protein inhibits apoptosis via enhanced Bcl-xL expression. Virology. vol 296. issue 1. 2002-07-25. PMID:12036320. |
therefore, in this study, we examined the mechanisms of the effects on cell apoptosis by core protein, using transiently transfected and magnetically collected core-producing hepg2 cells. |
2002-07-25 |
2023-08-12 |
Not clear |
| Gregor Fürstenberger, Hans-Jörg Sen. Insulin-like growth factors and cancer. The Lancet. Oncology. vol 3. issue 5. 2002-07-08. PMID:12067807. |
physiologically, igf1 is the major mediator of the effects of the growth hormone; it thus has a strong influence on cell proliferation and differentiation and is a potent inhibitor of apoptosis. |
2002-07-08 |
2023-08-12 |
Not clear |
| A Kapanen, J Ilvesaro, A Danilov, J Ryhänen, P Lehenkari, J Tuukkane. Behaviour of nitinol in osteoblast-like ROS-17 cell cultures. Biomaterials. vol 23. issue 3. 2002-07-02. PMID:11771684. |
the effects of nitinol on cell death rate, the apoptosis rate and the formation of local contacts were studied on rat osteosarcoma cell line ros-17 in 48-h cultures. |
2002-07-02 |
2023-08-12 |
rat |
| Hen-Li Chen, Burak Demiralp, Abraham Schneider, Amy J Koh, Caroline Silve, Cun-Yu Wang, Laurie K McCaule. Parathyroid hormone and parathyroid hormone-related protein exert both pro- and anti-apoptotic effects in mesenchymal cells. The Journal of biological chemistry. vol 277. issue 22. 2002-07-02. PMID:11897779. |
furthermore, the effects of pth and pthrp on apoptosis were dramatically dependent on cell status. |
2002-07-02 |
2023-08-12 |
Not clear |
| J Keelan, R Helliwell, B Nijmeijer, E Berry, T Sato, K Marvin, M Mitchell, R Gilmou. 15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. Prostaglandins & other lipid mediators. vol 66. issue 4. 2002-06-27. PMID:11785780. |
while ciglitizone also induced apoptosis, rosiglitazone had no effect on cell viability. |
2002-06-27 |
2023-08-12 |
Not clear |
| W M Liu, A J Lawrence, S P Joe. The importance of drug scheduling and recovery phases in determining drug activity. Improving etoposide efficacy in BCR-ABL-positive CML cells. European journal of cancer (Oxford, England : 1990). vol 38. issue 6. 2002-06-27. PMID:11937320. |
we have investigated the effect of etoposide schedule on cell cycle distribution, apoptosis and p21(waf1) and cdk1(p34) status in two bcr-abl-positive chronic myeloid leukaemia (cml) cell lines (k562 and ku812) and two small cell lung cancer (sclc) cell lines (h69 and glc4). |
2002-06-27 |
2023-08-12 |
Not clear |
| R Tabrizi, F X Mahon, P Cony Makhoul, V Lagarde, F Lacombe, P Berthaud, J V Melo, J Reiffers, F Bello. Resistance to daunorubicin-induced apoptosis is not completely reversed in CML blast cells by STI571. Leukemia. vol 16. issue 6. 2002-06-24. PMID:12040447. |
on cell lines, the effect of dnr was negligible, whereas sti571 induced 10 to 35% of apoptosis in 18 h. sti571 sensitized ar230, lama84 and k562 cells to dnr when apoptosis was measured at the mitochondrial and membrane but not the nuclear levels. |
2002-06-24 |
2023-08-12 |
Not clear |
| Hang Chang, Shih-Ying Tsai, Yi Chang, Ta-Liang Chen, Ruei-Ming Che. Therapeutic concentrations of propofol protects mouse macrophages from nitric oxide-induced cell death and apoptosis. Canadian journal of anaesthesia = Journal canadien d'anesthesie. vol 49. issue 5. 2002-06-13. PMID:11983662. |
to evaluate the potential effect of a clinically relevant concentration of propofol (ppf) on cell viability and nitric oxide-induced macrophage apoptosis. |
2002-06-13 |
2023-08-12 |
mouse |
| R T Cui, G Cai, Z B Yin, Y Cheng, Q H Yang, T Tia. Transretinoic acid inhibits rats gastric epithelial dysplasia induced by N-methyl-N-nitro-N-nitrosoguanidine: influences on cell apoptosis and expression of its regulatory genes. World journal of gastroenterology. vol 7. issue 3. 2002-06-05. PMID:11819797. |
transretinoic acid inhibits rats gastric epithelial dysplasia induced by n-methyl-n-nitro-n-nitrosoguanidine: influences on cell apoptosis and expression of its regulatory genes. |
2002-06-05 |
2023-08-12 |
rat |
| K A Naidu, J L Tang, K A Naidu, L D Prockop, S V Nicosia, D Coppol. Antiproliferative and apoptotic effect of ascorbyl stearate in human glioblastoma multiforme cells: modulation of insulin-like growth factor-I receptor (IGF-IR) expression. Journal of neuro-oncology. vol 54. issue 1. 2002-05-15. PMID:11763418. |
in this study, we present data on in vitro effect of ascorbyl stearate (asc-s), a liphophilic derivative of ascorbic acid on cell proliferation, transformation, apoptosis and modulation of expression of insulin-like growth factor-i receptor (igf-ir) in human glioblastoma multiforme (t98g) cells. |
2002-05-15 |
2023-08-12 |
human |
| Patrick Diel, Sabine Olff, Simone Schmidt, Horst Michn. Effects of the environmental estrogens bisphenol A, o,p'-DDT, p-tert-octylphenol and coumestrol on apoptosis induction, cell proliferation and the expression of estrogen sensitive molecular parameters in the human breast cancer cell line MCF-7. The Journal of steroid biochemistry and molecular biology. vol 80. issue 1. 2002-05-14. PMID:11867264. |
in the presented study, we have analysed effects of the environmental estrogens bisphenol a (bpa), p-tert-octylphenol (oct), o,p'-ddt (ddt) and coumestrol (cou) on cell proliferation, apoptosis induction, progesterone receptor (pr) and androgen receptor (ar) mrna expression and er alpha protein expression in comparison to estradiol (e2) and the selective er modulator (serm) raloxifene (ral) and the pure antiestrogen faslodex (ici 182780) in the human breast cancer cell line mcf-7. |
2002-05-14 |
2023-08-12 |
human |