| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arnold H van der Luit, Marianne Budde, Paula Ruurs, Marcel Verheij, Wim J van Blitterswij. Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis. The Journal of biological chemistry. vol 277. issue 42. 2002-12-19. PMID:12183451. |
the synthetic alkyl-lysophospholipid (alp), 1-o-octadecyl-2-o-methyl-rac-glycero-3-phosphocholine, is an antitumor agent that acts on cell membranes and can induce apoptosis. |
2002-12-19 |
2023-08-12 |
mouse |
| Stefania Merighi, Prisco Mirandola, Daniela Milani, Katia Varani, Stefania Gessi, Karl-Norbert Klotz, Edward Leung, Pier Giovanni Baraldi, Pier Andrea Bore. Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. The Journal of investigative dermatology. vol 119. issue 4. 2002-12-10. PMID:12406340. |
adenosine displays contradictory effects on cell growth: it improves cell proliferation, but it may also induce apoptosis and impair cell survival. |
2002-12-10 |
2023-08-12 |
human |
| Jerry Jaboin, Jason Wild, Habib Hamidi, Chand Khanna, Chong Jai Kim, Robert Robey, Susan E Bates, Carol J Thiel. MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors. Cancer research. vol 62. issue 21. 2002-12-10. PMID:12414635. |
however, the effects on cell cycle were diverse because in some cases ms-275 induced an increase in g(1) or g(2), whereas in others, there was an induction of apoptosis. |
2002-12-10 |
2023-08-12 |
mouse |
| E N Sevost'ianov, R U Giniatullin, E N Gorskova, S N Teplov. [Keratocyte apoptosis in keratoconus]. Vestnik oftalmologii. vol 118. issue 4. 2002-11-26. PMID:12371322. |
estimation of the volumic share of keratocytes expressing cd95 on cell membrane showed it to be almost 8-fold higher and apoptosis index almost 5-fold higher in the keratocone corneal disks than in the control. |
2002-11-26 |
2023-08-12 |
human |
| Mauro Vairano, Cinzia Dello Russo, Giacomo Pozzoli, Alessandra Battaglia, Giovanni Scambia, Giuseppe Tringali, Maria Antonietta Aloe-Spiriti, Paolo Preziosi, Pierluigi Navarr. Erythropoietin exerts anti-apoptotic effects on rat microglial cells in vitro. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270034. |
we found that: (i) epo exerted a marked stimulatory effect on microglial cell viability, assessed through the mts assay, whereas astrocytes were almost unaffected; (ii) the cytokine increased microglial cell population size in a concentration-dependent manner; however, as microglia cultures undergo spontaneous apoptosis after separation from astrocytes, the apparent effect on cell proliferation could be attributed to epo antagonism of normal apoptosis; (iii) subsequent flow cytometry analysis on microglial cells demonstrated both the trophic role of factor(s) released by astrocytes in mixed cultures, and the putative anti-apoptotic action of epo; (iv) the latter was further confirmed through the assessment of gene expression of anti- and pro-apoptotic factors, which showed that epo is able to shift the bcl : bax ratio towards a net anti-apoptotic effect; (v) epo did not affect the pro-inflammatory function of microglial cells. |
2002-11-22 |
2023-08-12 |
rat |
| N Zaffaroni, S Lualdi, R Villa, D Bellarosa, C Cermele, P Felicetti, C Rossi, L Orlandi, M G Daidon. Inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells. European journal of cancer (Oxford, England : 1990). vol 38. issue 13. 2002-11-12. PMID:12175697. |
inhibition of telomerase activity by a distamycin derivative: effects on cell proliferation and induction of apoptosis in human cancer cells. |
2002-11-12 |
2023-08-12 |
human |
| Mi-Hyeon Jang, Min-Chul Shin, Sae-Bin Jung, Taeck-Hyun Lee, Geon-Ho Bahn, Yunhee Kim Kwon, Ee-Hwa Kim, Chang-Ju Ki. Alcohol and nicotine reduce cell proliferation and enhance apoptosis in dentate gyrus. Neuroreport. vol 13. issue 12. 2002-10-23. PMID:12218695. |
in the present study, the effects of alcohol and nicotine on cell proliferation and apoptosis in the dentate gyrus of young rats were investigated. |
2002-10-23 |
2023-08-12 |
rat |
| G J C M van den Bemd, G T G Chan. Vitamin D and vitamin D analogs in cancer treatment. Current drug targets. vol 3. issue 1. 2002-10-22. PMID:11899952. |
the mechanisms by which 1,25-(oh)2d3 and 1,25-(oh)2d3 analogs exert their growth-inhibitory effects are not clear but include effects on cell differentiation, apoptosis, cell cycle regulation, metastases, and angiogenesis. |
2002-10-22 |
2023-08-12 |
Not clear |
| Jeffrey C Webster, Reid M Huber, Rebecca L Hanson, Paul M Collier, Thomas F Haws, Juliane K Mills, Timothy C Burn, Elizabeth A Allegrett. Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types. Endocrinology. vol 143. issue 10. 2002-10-21. PMID:12239098. |
treatment of a549 cells with tnf-alpha and/or dexamethasone had no effect on cell death, but the two agents were able to inhibit interferon-gamma/anti-fas antibody-mediated apoptosis. |
2002-10-21 |
2023-08-12 |
human |
| Weiqin Jiang, Zongjian Zhu, Neehar Bhatia, Rajesh Agarwal, Henry J Thompso. Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis. Cancer research. vol 62. issue 18. 2002-10-08. PMID:12234997. |
mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis. |
2002-10-08 |
2023-08-12 |
mouse |
| John W Savopoulos, Stephen Dowd, Carolyn Armour, Paul S Carter, Catherine J Greenwood, David Mills, David Powell, Gary R Pettman, Owen Jenkins, Frank S Walsh, Karen L Philpot. Expression and purification of functional JNK2beta2: perspectives on high-level production of recombinant MAP kinases. Protein expression and purification. vol 24. issue 1. 2002-10-03. PMID:11812219. |
of this family, the c-jun n-terminal kinases (jnks) are members which, depending on cell type, have been shown to activate the transcription of genes involved in the inflammatory response, apoptosis, and hypertrophy. |
2002-10-03 |
2023-08-12 |
Not clear |
| D O Cliche, S Girouard, N Bissonnette, D J Huntin. Inhibition of ultraviolet B (UVB) induced apoptosis in A431 cells by mimosine is not dependent on cell cycle arrest. Canadian journal of physiology and pharmacology. vol 80. issue 7. 2002-09-27. PMID:12182323. |
inhibition of ultraviolet b (uvb) induced apoptosis in a431 cells by mimosine is not dependent on cell cycle arrest. |
2002-09-27 |
2023-08-12 |
human |
| Shin-Ho Kim, Hyun-Bae Kim, Mi-Hyeon Jang, Baek-Vin Lim, Youn-Jung Kim, Young-Pyo Kim, Sung-Soo Kim, Ee-Hwa Kim, Chang-Ju Ki. Treadmill exercise increases cell proliferation without altering of apoptosis in dentate gyrus of Sprague-Dawley rats. Life sciences. vol 71. issue 11. 2002-09-18. PMID:12106598. |
the effects of forced treadmill exercise on cell proliferation and apoptosis in the hippocampal dentate gyrus in sprague-dawley rats were investigated. |
2002-09-18 |
2023-08-12 |
rat |
| Adrienne L Katner, Quoc Bao Ly Hoang, Praveen Gootam, Ewa Jaruga, Quangwei Ma, James Gnarra, Walter Rayfor. Induction of cell cycle arrest and apoptosis in human prostate carcinoma cells by a recombinant adenovirus expressing p27(Kip1). The Prostate. vol 53. issue 1. 2002-09-17. PMID:12210483. |
effects of p27(kip1) on cell cycle and apoptosis were analyzed. |
2002-09-17 |
2023-08-12 |
human |
| Jeong Hee Kim, Eun-Mi Ju, Dug Keun Lee, Hyun Jin Hwan. Induction of apoptosis by momordin I in promyelocytic leukemia (HL-60) cells. Anticancer research. vol 22. issue 3. 2002-09-13. PMID:12168888. |
we studied the effect of momordin i, a compound purified from a plant, ampelopsis japonica, on cell proliferation and induction of apoptosis in human promyelocytic leukemia (hl-60) cells. |
2002-09-13 |
2023-08-12 |
human |
| Tze-Chen Hsieh, Wen Xiong, Frank Traganos, Zbigniew Darzynkiewicz, Joseph M W. Effects of PC-SPES on proliferation and expression of AR/PSA in androgen-responsive LNCaP cells are independent of estradiol. Anticancer research. vol 22. issue 4. 2002-09-13. PMID:12174883. |
to test this hypothesis, we compared estradiol (1 nm), potentially an active principle in pc-spes, with pc-spes (using an amount equivalent to 1 nm estradiol) on cell proliferation, induction of apoptosis, and regulation of prostate specific genes, psa and ar, in androgen-responsive lncap cells. |
2002-09-13 |
2023-08-12 |
human |
| Angela M Djanani, Ch M Kähle. Modulation of inflammation by vasoactive intestinal peptide and bombesin: lack of effects on neutrophil apoptosis. Acta medica Austriaca. vol 29. issue 3. 2002-09-11. PMID:12168570. |
for measuring effects on cell survival and apoptosis, trypan dye exclusion, colorimetric mtt assay to assess cell survival, and caspase-3 assay and annexin-v binding for analysing apoptosis rates were used. |
2002-09-11 |
2023-08-12 |
human |
| Mu-Shui Dai, Nathalie Chevallier, Stacie Stone, Michael C Heinrich, Melanie McConnell, Tanja Reuter, Hal E Broxmeyer, Jonathan D Licht, Li Lu, Maureen E Hoatli. The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. The Journal of biological chemistry. vol 277. issue 29. 2002-09-06. PMID:11986317. |
the effects of the fanconi anemia zinc finger (fazf) on cell cycle, apoptosis, and proliferation are differentiation stage-specific. |
2002-09-06 |
2023-08-12 |
human |
| Suzanne Jozan, Sebastien Paute, Monique Courtade-Saïdi, Severine Julié, Simone Vidal, Roland Bugat, Annie Valett. All trans retinoic acid enhances CDDP-induced apoptosis: modulation of the CDDP effect on cell cycle progression. International journal of oncology. vol 20. issue 6. 2002-08-29. PMID:12012012. |
all trans retinoic acid enhances cddp-induced apoptosis: modulation of the cddp effect on cell cycle progression. |
2002-08-29 |
2023-08-12 |
Not clear |
| Jun-Kyu Yeo, Soon-Do Cha, Chi-Heum Cho, Sang-Pyo Kim, Jae-We Cho, Won-Ki Baek, Min-Ho Suh, Taeg Kyu Kwon, Jong-Wook Park, Seong-Il Su. Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells. Cancer letters. vol 182. issue 1. 2002-08-29. PMID:12175527. |
se-msc displayed strong inhibitory effects on cell proliferation and viability of skov-3 cells in dose and time dependent manners and induced apoptosis. |
2002-08-29 |
2023-08-12 |
human |