| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanqing Zheng, Genghua Xu, Zhengwei Lue, Xinyu Zhou, Ning Wang, Yun Ma, Wenyue Yuan, Lushan Yu, Danyan Zhu, Xiangnan Zhan. Nervonic acid protects against oligodendrocytes injury following chronic cerebral hypoperfusion in mice. European journal of pharmacology. 2024-08-25. PMID:39182543. |
moreover, na mitigated demyelination and loss of oligodendrocytes in the corpus callosum and hippocampus of ruccao-treated mice, and prevented oligodendrocyte apoptosis. |
2024-08-25 |
2024-08-28 |
mouse |
| Woojin Kim, María Cecilia Angul. Unraveling the role of oligodendrocytes and myelin in pain. Journal of neurochemistry. 2024-08-20. PMID:39162089. |
additionally, oligodendrocyte apoptosis in brain regions such as the medial prefrontal cortex is linked to opioid-induced hyperalgesia, highlighting their role in central pain mechanisms. |
2024-08-20 |
2024-08-22 |
Not clear |
| Cristian De Gregorio, Javiera Gallardo, Pablo Berríos-Cárcamo, Álex Handy, Daniela Santapau, Antonia González-Madrid, Marcelo Ezquer, Paola Morales, Alejandro Luarte, Daniela Corvalán, Úrsula Wyneken, Fernando Ezque. Methadone directly impairs central nervous system cells in vitro. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043899. |
in animal models, prenatal methadone exposure results in detrimental consequences to the central nervous system, such as: (i) increased neuronal apoptosis; (ii) disruption of oligodendrocyte maturation and increased apoptosis and (iii) increased microglia and astrocyte activation. |
2024-07-23 |
2024-07-26 |
rat |
| Cristian De Gregorio, Javiera Gallardo, Pablo Berríos-Cárcamo, Álex Handy, Daniela Santapau, Antonia González-Madrid, Marcelo Ezquer, Paola Morales, Alejandro Luarte, Daniela Corvalán, Úrsula Wyneken, Fernando Ezque. Methadone directly impairs central nervous system cells in vitro. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043899. |
apoptosis of oligodendrocyte precursors was determined by cleaved caspase-3 detection. |
2024-07-23 |
2024-07-26 |
rat |
| Cristian De Gregorio, Javiera Gallardo, Pablo Berríos-Cárcamo, Álex Handy, Daniela Santapau, Antonia González-Madrid, Marcelo Ezquer, Paola Morales, Alejandro Luarte, Daniela Corvalán, Úrsula Wyneken, Fernando Ezque. Methadone directly impairs central nervous system cells in vitro. Scientific reports. vol 14. issue 1. 2024-07-23. PMID:39043899. |
furthermore, it led to increased oligodendrocyte apoptosis and a reduction in the myelinating capacity of these cells, and promoted the proinflammatory activation of microglia and astrocytes. |
2024-07-23 |
2024-07-26 |
rat |
| Yaping Zhang, Lei Tian, Jiang Chen, Xuan Liu, Kang Li, Huanliang Liu, Wenqing Lai, Yue Shi, Bencheng Lin, Zhuge X. Selective bioaccumulation of polystyrene nanoplastics in fetal rat brain and damage to myelin development. Ecotoxicology and environmental safety. vol 278. 2024-05-07. PMID:38714083. |
compared with control rats, ps-nps exposure caused a significant reduction in myelin basic protein (mbp) and myelin oligodendrocyte glycoprotein (mog) expression, a decrease in myelin thickness, an increase in cell apoptosis, and a decline in the oligodendrocyte population. |
2024-05-07 |
2024-05-27 |
rat |
| Zhongni Li, Feng Zhang, Li Huang, Jiehong Deng, Yutong Pan, Ting Xu, Jingyi Liu, Na Gao, Rongrong Duan, Chunyan Shao, Chan Wu, Minrong Wang, Liqun L. Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia. Neurochemical research. 2023-11-28. PMID:38015410. |
akt/mtor pathway agonist sc79 inhibits autophagy and apoptosis of oligodendrocyte precursor cells associated with neonatal white matter dysplasia. |
2023-11-28 |
2023-11-29 |
rat |
| Zhongni Li, Feng Zhang, Li Huang, Jiehong Deng, Yutong Pan, Ting Xu, Jingyi Liu, Na Gao, Rongrong Duan, Chunyan Shao, Chan Wu, Minrong Wang, Liqun L. Akt/mTOR Pathway Agonist SC79 Inhibits Autophagy and Apoptosis of Oligodendrocyte Precursor Cells Associated with Neonatal White Matter Dysplasia. Neurochemical research. 2023-11-28. PMID:38015410. |
white matter dysplasia (wmd) in preterm infants due to intrauterine inflammation is caused by excessive apoptosis of oligodendrocyte precursor cells (opcs). |
2023-11-28 |
2023-11-29 |
rat |
| Zhaokui Zhu, Sisi Mo, Xinyu Wang, Meng Meng, Lixing Qia. Circ-AGTPBP1 promotes white matter injury through miR-140-3p/Pcdh17 axis role of Circ-AGTPBP1 in white matter injury. Journal of bioenergetics and biomembranes. 2023-11-23. PMID:37994971. |
conversely, overexpression of circ-agtpbp1 reduces the proliferative and migrative potential of oligodendrocyte progenitor cells and promotes apoptosis. |
2023-11-23 |
2023-11-29 |
rat |
| Kai Chen, Xiaojin Wei, Ruixuan Wang, Lin Yang, Dingquan Zou, Yaping Wan. BMP7 alleviates trigeminal neuralgia by reducing oligodendrocyte apoptosis and demyelination. The journal of headache and pain. vol 24. issue 1. 2023-10-26. PMID:37875834. |
bmp7 alleviates trigeminal neuralgia by reducing oligodendrocyte apoptosis and demyelination. |
2023-10-26 |
2023-11-08 |
rat |
| Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B Mulinyawe, Jun Hee Kim, Lu O Su. Autophagy collaborates with apoptosis pathways to control oligodendrocyte number. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543947. |
autophagy collaborates with apoptosis pathways to control oligodendrocyte number. |
2023-08-06 |
2023-08-14 |
Not clear |
| Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B Mulinyawe, Jun Hee Kim, Lu O Su. Autophagy collaborates with apoptosis pathways to control oligodendrocyte number. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543947. |
here, we show that autophagy, an evolutionarily conserved cellular process that promotes cell survival under physiological conditions, elicits premyelinating oligodendrocyte apoptosis during development. |
2023-08-06 |
2023-08-14 |
Not clear |
| Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B Mulinyawe, Jun Hee Kim, Lu O Su. Autophagy collaborates with apoptosis pathways to control oligodendrocyte number. Cell reports. vol 42. issue 8. 2023-08-06. PMID:37543947. |
autophagy functions cell autonomously in the premyelinating oligodendrocyte to trigger cell apoptosis, and it genetically interacts with the tfeb pathway to limit oligodendrocyte number across diverse brain regions. |
2023-08-06 |
2023-08-14 |
Not clear |
| Vera Tscherrig, Sophie Cottagnoud, Valérie Haesler, Patricia Renz, Daniel Surbek, Andreina Schoeberlein, Marianne Simone Joerger-Messerl. MicroRNA Cargo in Wharton's Jelly MSC Small Extracellular Vesicles: Key Functionality to In Vitro Prevention and Treatment of Premature White Matter Injury. Stem cell reviews and reports. 2023-07-31. PMID:37523115. |
small ev initiated oligodendrocyte maturation and reduced ogd/r-mediated neuronal apoptosis. |
2023-07-31 |
2023-08-14 |
Not clear |
| Jie Qu, Hang-Fan Zong, Yi Shan, Shan-Chun Zhang, Wei-Ping Guan, Yang Yang, Heng-Li Zha. Piezo1 suppression reduces demyelination after intracerebral hemorrhage. Neural regeneration research. vol 18. issue 8. 2023-02-08. PMID:36751801. |
intraperitoneal injection of dooku1 to inhibit piezo1 resulted in marked alleviation of brain edema, myelin sheath loss, and degeneration in injured tissue, a substantial reduction in oligodendrocyte apoptosis, and a significant improvement in neurological function. |
2023-02-08 |
2023-08-14 |
mouse |
| Tingxin Zhang, Han-Gyu Bae, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Jumin Xue, Sabeen Wazir, Sara B Mulinyawe, Jun Hee Kim, Lu O Su. Autophagy collaborates with apoptosis pathways to control myelination specificity and function. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36712125. |
here, we show that autophagy, an evolutionarily conserved cellular process that promotes cell survival under canonical settings, elicits premyelinating oligodendrocyte apoptosis during development and regulates critical aspects of nerve pulse propagation. |
2023-01-30 |
2023-08-14 |
Not clear |
| Maryam Akhavan Tavakoli, Maryam Soleimani, Hassan Marzban, Ronak Shabani, Fatemeh Moradi, Marziyeh Ajdary, Mehdi Mehdizade. Autophagic Molecular Alterations in the Mouse Cerebellum Experimental Autoimmune Encephalomyelitis Model Following Treatment with Cannabidiol and Fluoxetine. Molecular neurobiology. 2022-12-28. PMID:36576709. |
the crosstalk between autophagy and apoptosis is one of the most important processes involved in the cell program death, and several mechanisms including oligodendrocyte apoptosis and autophagy play significant roles in activating macrophages, microglial cells, and finally demyelination in neurodegenerative disease. |
2022-12-28 |
2023-08-14 |
mouse |
| Krista Lamorie-Foote, Qinghai Liu, Kristina Shkirkova, Brandon Ge, Shannon He, Todd E Morgan, Wendy J Mack, Constantinos Sioutas, Caleb E Finch, William J Mac. Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice. Journal of neuroscience research. 2022-12-04. PMID:36464774. |
particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice. |
2022-12-04 |
2023-08-14 |
mouse |
| Melanie Gil, Vivian Gam. Emerging mitochondrial-mediated mechanisms involved in oligodendrocyte development. Journal of neuroscience research. 2022-12-03. PMID:36461887. |
myelination is an energy-consuming event, thus, understanding the interplay between mitochondrial dynamics, metabolism, and apoptosis will provide further insight into mechanisms that mediate oligodendrocyte development in healthy and disease states. |
2022-12-03 |
2023-08-14 |
Not clear |
| Weijie Xie, Yanqin Zeng, Yunqiu Zheng, Bin Ca. Activated AMPK Protects Against Chronic Cerebral Ischemia in Bilateral Carotid Artery Stenosis Mice. Cellular and molecular neurobiology. 2022-11-28. PMID:36441266. |
three months after bcas, we measured the ampk protein expression, spatial learning and memory, nissl bodies, cell apoptosis, astrocyte activation, and oligodendrocyte maturation. |
2022-11-28 |
2023-08-14 |
mouse |