All Relations between apoptosis and p53

Publication Sentence Publish Date Extraction Date Species
Yaowen Cui, Zhaolun He, Tingting Chen, Xinjian Ren, Jing Xu, Shouguo Zhang, Tao Peng, Shuchen Liu, Lin Wan. Design, synthesis, biological evaluation and in silico studies of novel quinoline derivatives as potential radioprotective molecules targeting the TLR2 and p53 pathways. European journal of medicinal chemistry. vol 268. 2024-02-20. PMID:38377827. in this paper, in order to find the potential novel compounds decreasing the radiation-induced damage by targeting p53 apoptosis pathway and tlr2 passway, a series of novel quinoline derivatives were designed, synthesized, and evaluated their biological activities. 2024-02-20 2024-02-23 mouse
Yaowen Cui, Zhaolun He, Tingting Chen, Xinjian Ren, Jing Xu, Shouguo Zhang, Tao Peng, Shuchen Liu, Lin Wan. Design, synthesis, biological evaluation and in silico studies of novel quinoline derivatives as potential radioprotective molecules targeting the TLR2 and p53 pathways. European journal of medicinal chemistry. vol 268. 2024-02-20. PMID:38377827. the mechanistic studies indicated that compound 5 acted on the p53 pathway to reduce radiation-induced cell apoptosis and at the same time stimulated tlr2 to up-regulate the expressions of radiation protection factors. 2024-02-20 2024-02-23 mouse
Tingting Zheng, Keke Chen, Xue Zhang, Huanhuan Feng, Yu Shi, Li Liu, Jun Zhang, Yun Che. Correction for: Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation. Aging. vol 16. issue 3. 2024-02-20. PMID:38378211. correction for: knockdown of txndc9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation. 2024-02-20 2024-02-23 Not clear
Mozaffarul Islam, Riyasdeen Anvarbatcha, Faisal Kunnathodi, Md Tanwir Athar, Mohammad Tari. Quinacrine enhances the efficacy of cisplatin by increasing apoptosis and modulating cancer survival proteins in a colorectal cancer cell line. Journal of cancer research and therapeutics. vol 19. issue 7. 2024-02-20. PMID:38376308. over-expression of p53 and inhibition of nf-kb sensitize several cancer cells towards cisplatin-induced apoptosis. 2024-02-20 2024-02-22 Not clear
Statement of Retraction: Dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box O3a (FOXO3a)/p53-upregulated modulator of apoptosis (PUMA) signaling signaling. Bioengineered. vol 15. issue 1. 2024-02-20. PMID:38376902. statement of retraction: dexmedetomidine attenuates ischemia and reperfusion-induced cardiomyocyte injury through p53 and forkhead box o3a (foxo3a)/p53-upregulated modulator of apoptosis (puma) signaling signaling. 2024-02-20 2024-02-22 Not clear
İpek Baysal, Serra Örsten, Görkem Cengiz, Emre Ünal, Ahmet Bülent Doğrul, Türkmen Çiftçi, Samiye Yabanoğlu Çiftçi, Devrim Akinci, Okan Akha. Assessing the Potential Apoptotic Effects of Different Hydatid Cyst Fluids on Human Healthy Hepatocytes and Hepatocellular Carcinoma Cells. Acta parasitologica. 2024-02-19. PMID:38372909. specifically, we examined their effects on cell proliferation, apoptosis sensitivity (bax/bcl-2), apoptosis-related p53 expression, and the expression of cancer-related microrna (hsa-mir-181b-3p). 2024-02-19 2024-02-21 human
İpek Baysal, Serra Örsten, Görkem Cengiz, Emre Ünal, Ahmet Bülent Doğrul, Türkmen Çiftçi, Samiye Yabanoğlu Çiftçi, Devrim Akinci, Okan Akha. Assessing the Potential Apoptotic Effects of Different Hydatid Cyst Fluids on Human Healthy Hepatocytes and Hepatocellular Carcinoma Cells. Acta parasitologica. 2024-02-19. PMID:38372909. treatment with both g1(a) and g1(h) hcf sensitized hepg2 and hc cell lines to apoptosis by modulating the bax/bcl-2 ratio, accompanied by upregulation of the p53 gene. 2024-02-19 2024-02-21 human
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim J Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C Hinte, Ferdinand von Meyenn, Albert J R Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesc. Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nature communications. vol 15. issue 1. 2024-02-15. PMID:38360943. importantly, this increase in lam abundance is strongly p53 dependent and partly mediated by p53-driven adipocyte apoptosis. 2024-02-15 2024-02-18 mouse
Xinping Guo, Ziang Qian, Su Jiang, Xiaobin Qian, Xianhui Ning, Shaowu Yin, Kai Zhan. Assessing the ecotoxicity of florfenicol exposure at environmental levels: A case study of histology, apoptosis and microbiota in hepatopancreas of Eriocheir sinensis. Ecotoxicology and environmental safety. vol 272. 2024-02-13. PMID:38350219. combined with the increased expression of apoptosis-related genes (caspase 3, caspase 8, p53, bax and bcl-2) at mrna and protein levels, activation of catalase (cat) and superoxide dismutase (sod), and malondialdehyde (mda) accumulation, ff exposure also induced oxidative stress, and apoptosis in hepatopancreas. 2024-02-13 2024-02-16 human
Jingyu Pan, Minxu Wang, Jiahua Zhu, Yuxing Huang, Fan Zhang, Erchao Li, Jianguang Qin, Liqiao Chen, Xiaodan Wan. Quantitative proteomic and metabolomic profiling reveals different osmoregulation mechanisms of tilapia cells coping with different hyperosmotic stress. Journal of proteomics. 2024-02-12. PMID:38346667. the pi3k-akt and p53 signaling pathways were involved in the stagnant stage of cell cycles and induction of cell apoptosis under both kinds of hyperosmotic stress. 2024-02-12 2024-02-15 Not clear
Mahdiyeh Bakhtiyari-Ramezani, Mojtaba Nohekhan, Mohammad Esmaeil Akbari, Fereshteh Abbasvandi, Mahdis Bayat, Atieh Akbari, Meysam Nasir. Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo study. Scientific reports. vol 14. issue 1. 2024-02-12. PMID:38347045. in vitro assessments on human gbm and normal astrocyte cell lines, using mtt assays, flow cytometry analysis, wound healing assays, and immunocytochemistry for caspase3 and p53 proteins, demonstrated that all studied plasma jets, especially indirect argon cap, selectively induced apoptosis, hindered tumor cell growth, and inhibited migration. 2024-02-12 2024-02-15 human
Yazhong Ma, Xiaotong Wang, Xin Li, Xi Chen, Zhifeng Teng, Xuekun Wang, Jie Yang, Guoyun Li. COP-22 Alleviates D-Galactose-Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice. Molecular neurobiology. 2024-02-12. PMID:38347285. we found that cop-22 could effectively protect against brain injury (sirt1, p53, p21, and p16) by inhibiting oxidative stress (nrf2 and ho-1), inflammation (il-6 and tnf-α), and apoptosis (bax and caspase-3) in d-gal-induced aging mice. 2024-02-12 2024-02-15 mouse
Stefano Pagano, Chiara Valenti, Paolo Negri, Monia Billi, Alessandro Di Michele, Stefano Bruscoli, Marta Febo, Maddalena Coniglio, Lorella Marinucc. Acute and chronic cannabidiol treatment: In vitro toxicological aspects on human oral cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-02-11. PMID:38342230. viability, morphology, migration, apoptosis and cell cycle, and expression of related genes (p53, bcl2, p21, and bax) and of endocannabinoid system receptors (cb1, cb2 and gpr55) with real-time pcr and dna damage with phospho-γ-h2ax immunofluorescence detection were analyzed. 2024-02-11 2024-02-14 human
Yeon-Jun Lee, Yanni Pan, Daewoo Lim, Seung-Hwan Park, Sin-Il Sin, KyuBum Kwack, Kun-Young Par. Broccoli Cultivated with Deep Sea Water Mineral Fertilizer Enhances Anti-Cancer and Anti-Inflammatory Effects of AOM/DSS-Induced Colorectal Cancer in C57BL/6N Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338927. in the colon tissue, the expression of p53 and p21 associated with cell cycle arrest increased, and that of bcl-2 associated with apoptosis decreased. 2024-02-10 2024-02-12 mouse
Beate Köberle, Svetlana Usanova, Andrea Piee-Staffa, Ulrike Heinicke, Philipp Clauss, Anamaria Brozovic, Bernd Kain. Strong apoptotic response of testis tumor cells following cisplatin treatment. International urology and nephrology. vol 56. issue 3. 2024-02-09. PMID:37891379. targeting the apoptotic pathway via sirna-mediated knockdown of p53 and fas reduced death receptor-mediated apoptosis and increased cisplatin resistance in ttc, indicating the involvement of fas-mediated apoptosis in the cisplatin ttc response. 2024-02-09 2024-02-11 Not clear
Xilin Li, Yuan Le, Yuxi Li, Si Chen, Lei Guo, Xin Fu, Mugimane G Manjanatha, Nan Me. Evaluation of weak genotoxicity of hydroxychloroquine in human TK6 cells. Toxicology letters. 2024-02-08. PMID:38311193. however, after 24-h treatment, both cq and hcq induced comparable and weak dna damage and mn formation in tk6 cells; upregulated p53 and p53-mediated dna damage responsive genes; and triggered apoptosis and mitochondrial damage that may partially contribute to the observed mn formation. 2024-02-08 2024-02-11 human
Te Liu, Sichao Huang, Qian Zhang, Yu Xia, Manjie Zhang, Bin Su. Reconciling ASPP-p53 binding mode discrepancies through an ensemble binding framework that bridges crystallography and NMR data. PLoS computational biology. vol 20. issue 2. 2024-02-07. PMID:38324587. aspp2 and iaspp bind to p53 through their conserved ank-sh3 domains to respectively promote and inhibit p53-dependent cell apoptosis. 2024-02-07 2024-02-10 Not clear
Ali Dakroub, Ali Dbouk, Aref Asfour, Suzanne A Nasser, Ahmed F El-Yazbi, Amirhossein Sahebkar, Assaad A Eid, Rabah Iratni, Ali H Ei. C-peptide in diabetes: A player in a dual hormone disorder? Journal of cellular physiology. 2024-02-03. PMID:38308646. it also prevents apoptosis by regulating hyperglycemia-induced p53 upregulation and mitochondrial adaptor p66shc overactivation, as well as reducing caspase-3 activity and promoting expression of b-cell lymphoma-2. 2024-02-03 2024-02-06 Not clear
Barbora Loncová, Zuzana Fabová, Vladimíra Mondočková, Radoslav Omelka, Abdel Halim Harrath, Alexander V Sirotki. Inhibition of vinculin activity has an adverse effect on porcine ovarian cells. Experimental cell research. 2024-02-03. PMID:38309674. the expression of vcl, accumulation of vcl protein, cell viability, proliferation (accumulation of pcna and cyclin b1), proportion of proliferative active cells, apoptosis (accumulation of bax, caspase 3, p53, antiapoptotic marker bcl2, and bax/bcl-2 ratio), dna fragmentation, and release of steroid hormones and igf-i were analyzed by rt‒qpcr, trypan blue exclusion test, quantitative immunocytochemistry, xtt assay, tunel assay, and elisa. 2024-02-03 2024-02-06 Not clear
Dwaipayan Bhattacharya, Madhu Rani Bharati, Kalyani Sakhare, Piyush Khandelia, Rajkumar Banerjee, Kumar Pranav Naraya. Steroid hormone receptor based gene delivery systems as potential oral cancer therapeutics. Biomedical materials (Bristol, England). 2024-01-30. PMID:38290150. transfection of oscc cells with exogenous, anticancer gene p53 lipoplexed with crude saponin-based liposome induced apoptosis of cancer cells via regulation of bax and bcl2 protein levels at levels comparable with pre-established delivery systems based on synthetic shr ligands. 2024-01-30 2024-02-02 human