| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi-Cun Chen, Dong-Dong Lu, Xiang-Rong Cao, Xi-Ran Zhan. RTN4-C gene expression in hepatocellular carcinoma and its influence on SMMC7721 cell growth and apoptosis. Yi chuan xue bao = Acta genetica Sinica. vol 32. issue 9. 2008-08-18. PMID:16201230. |
growth curve of smmc7721 measured by mtt and apoptosis indentified with acridine orange staining were examined to demonstrate the effect of rtn4-c on smmc7721. |
2008-08-18 |
2023-08-12 |
human |
| Bin Wu, Qiang Zhang, Weiming Shen, Jun Zh. Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line. Molecular and cellular biochemistry. vol 313. issue 1-2. 2008-08-18. PMID:18398671. |
cell growth was assessed by mtt assay, cell cycle and apoptosis were assessed by flow-cytometric analysis, and the expression of major proteins regulating cell cycle and apoptosis was also detected. |
2008-08-18 |
2023-08-12 |
human |
| Dadong Guo, Chunhui Wu, Xiaomao Li, Hui Jiang, Xuemei Wang, Baoan Che. In vitro cellular uptake and cytotoxic effect of functionalized nickel nanoparticles on leukemia cancer cells. Journal of nanoscience and nanotechnology. vol 8. issue 5. 2008-08-13. PMID:18572641. |
the results of 3-(4,5-dimethylthiazol-2-yl)2,5-diphenyl-tetrazolium bromide (mtt) assay, dna fragmentation and flow cytometry studies demonstrate that the ni nps could exert cytotoxicity to leukemia k562 cells at high concentration, and subsequently induce both apoptosis and necrosis of target cancer cells, whilst it had little impact on target cells when at low concentration. |
2008-08-13 |
2023-08-12 |
Not clear |
| Yusuf Baran, Ali Ugur Ural, Ufuk Gundu. Mechanisms of cellular resistance to imatinib in human chronic myeloid leukemia cells. Hematology (Amsterdam, Netherlands). vol 12. issue 6. 2008-08-08. PMID:17852433. |
mtt cell proliferation, cell cycle analyses and trypan blue dye exclusion analyses showed that meg-01/ima-1 cells were resistant to imatinib-induced apoptosis as compared to parental sensitive cells. |
2008-08-08 |
2023-08-12 |
human |
| Frank Wehner, Andrea Nören-Müller, Oliver Müller, Ivan Reis-Corrêa, Athanassios Giannis, Herbert Waldman. Indoloquinolizidine derivatives as novel and potent apoptosis inducers and cell-cycle blockers. Chembiochem : a European journal of chemical biology. vol 9. issue 3. 2008-08-07. PMID:18189263. |
a collection of approximately 11 000 natural-product derived and inspired compounds was screened for potential apoptosis inducers in the human tumour cell lines hepg2 (liver), hela (cervix) and mcf-7 (breast) by means of mtt and atp-luminescence assays, automated cell counting, caspase 3/7 assay as well as by fluorescence activated cell sorting (facs) analysis. |
2008-08-07 |
2023-08-12 |
human |
| A R Alvaro, J Martins, A C Costa, E Fernandes, F Carvalho, A F Ambrósio, C Cavada. Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy. Neuroscience. vol 152. issue 1. 2008-08-05. PMID:18249070. |
mdma induced necrosis [mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and propidium iodide assays] and apoptosis (immunoreactivity of cleaved caspase-3) in mixed cultures of retinal neural cells (neurons, macroglia and microglia), in a concentration-dependent manner. |
2008-08-05 |
2023-08-12 |
rat |
| Wei Zhou, Xu Zhu, Liang Zhu, Yong Yao Cui, Hao Wang, Hong Qi, Qiu Shi Ren, Hong Zhuan Che. Neuroprotection of muscarinic receptor agonist pilocarpine against glutamate-induced apoptosis in retinal neurons. Cellular and molecular neurobiology. vol 28. issue 2. 2008-07-30. PMID:18172757. |
in rat primary retinal cultures, identification of neuron, cell viability, apoptosis, intracellular ca(2+) concentration, mitochondrial membrane potential, gene expression were studied by immunofluorescence, mtt, high content scanning, confocal microscopy, reverse-transcription pcr, and western blot analysis, respectively. |
2008-07-30 |
2023-08-12 |
rat |
| Jun Panee, Wanyu Liu, Yanling Lin, Christy Gilman, Marla J Berr. A novel function of bamboo extract in relieving lipotoxicity. Phytotherapy research : PTR. vol 22. issue 5. 2008-07-30. PMID:18350521. |
cell viability was measured by mtt assay and cell apoptosis was monitored by annexin v staining. |
2008-07-30 |
2023-08-12 |
mouse |
| Süreyya Savaşan, Steven Buck, Oner Ozdemir, Merlin Hamre, Barbara Asselin, Jeannette Pullen, Yaddanapudi Ravindranat. Evaluation of cytotoxicity by flow cytometric drug sensitivity assay in childhood T-cell acute lymphoblastic leukemia. Leukemia & lymphoma. vol 46. issue 6. 2008-07-29. PMID:16019527. |
spontaneous apoptosis was correlated with cytotoxicity rates for both drugs by fcdsa, but not with the results obtained by mtt assay. |
2008-07-29 |
2023-08-12 |
Not clear |
| Likun Chen, Youjian He, He Huang, Hai Liao, Weidong We. Selective COX-2 inhibitor celecoxib combined with EGFR-TKI ZD1839 on non-small cell lung cancer cell lines: in vitro toxicity and mechanism study. Medical oncology (Northwood, London, England). vol 25. issue 2. 2008-07-29. PMID:18172786. |
mtt growth assay showed the synergistic therapeutic effect of certain concentration of celecoxib combined with zd1839 and synergistic apoptosis effect was detected by hoechest33258 fluorescence staining and flow cytometric analysis. |
2008-07-29 |
2023-08-12 |
Not clear |
| Colin A Thompson, Philip C Burcha. Protein alkylation, transcriptional responses and cytochrome c release during acrolein toxicity in A549 cells: influence of nucleophilic culture media constituents. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 4. 2008-07-25. PMID:18282682. |
cell viability was assessed using the mtt assay, while heme oxygenase-1 (ho-1) and cytoplasmic cytochrome c were measured as respective markers of transcriptional response and apoptosis. |
2008-07-25 |
2023-08-12 |
cattle |
| Lukui Chen, Guohong Zhuang, Wenzhu Li, Yunsheng Liu, Junqing Zhang, Xinhua Tia. RGD-FasL induces apoptosis of pituitary adenoma cells. Cellular & molecular immunology. vol 5. issue 1. 2008-07-15. PMID:18318996. |
cytotoxicity exerted by rgd-fasl on tumor cells was measured with mtt assay and the induced apoptosis was determined by agarose gel electrophoresis. |
2008-07-15 |
2023-08-12 |
Not clear |
| Zhiwei Wang, Wen Song, Amro Aboukameel, Mussop Mohammad, Guoping Wang, Sanjeev Banerjee, Dejuan Kong, Shaomeng Wang, Fazlul H Sarkar, Ramzi M Mohamma. TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer. International journal of cancer. vol 123. issue 4. 2008-07-15. PMID:18528859. |
using multiple cellular and molecular approaches such as mtt assay, apoptosis enzyme-linked immunosorbent assay, real-time reverse transcription-polymerase chain reaction, western blotting, electrophoretic mobility shift assay for measuring dna binding activity of nf-kappab, migration, invasion and angiogenesis assays, we found that tw-37, in nanomolar concentrations, inhibited cell growth in a dose- and time-dependent manner. |
2008-07-15 |
2023-08-12 |
human |
| Huiyu Li, Liqiong Liu, Tiannan Guo, Jiahua Zhang, Xiaoqing Li, Wen Du, Wei Liu, Xiangjun Chen, Shi'ang Huan. Expression and functional role of HERG1, K+ channels in leukemic cells and leukemic stem cells. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 27. issue 3. 2008-07-02. PMID:17641836. |
the functional role of herg1 k+ channels in leukemic cell proliferation was measured by mtt assay, and cell cycle and apoptosis were analyzed by flow cytometry. |
2008-07-02 |
2023-08-12 |
Not clear |
| Liang Wang, Yalan Bi, Fuqing Zeng, Liduan Zheng, Qiangsong Ton. Expression of X-linked inhibitor of apoptosis protein and its effect on chemotherapeutic sensitivity of bladder carcinoma. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 27. issue 3. 2008-07-02. PMID:17641843. |
the in vitro growth of bladder carcinoma cells was analyzed by mtt colorimetry, and the apoptosis rate was assayed by tunel methods. |
2008-07-02 |
2023-08-12 |
Not clear |
| Mingchang Zhang, Fang Bian, Chenting Wen, Nian Ha. Inhibitory effect of curcumin on proliferation of human pterygium fibroblasts. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 27. issue 3. 2008-07-02. PMID:17641858. |
in order to investigate the effect of curcumin on proliferation and apoptosis of human pterygium fibroblasts (hpf) in culture and search for a new method to prevent the recurrence after pterygium surgery, hpf was incubated with 0-160 micromol/l curcumin for 24-96 h. the mtt method was used to assay the biologic activities of curcumin at different time points and different doses. |
2008-07-02 |
2023-08-12 |
human |
| Guo-You Zhang, Cheng-Gang Yi, Xuan Li, Yan Zheng, Zhan-Guo Niu, Wei Xia, Zhou Meng, Cheng-Yue Meng, Shu-Zhong Gu. Inhibition of vascular endothelial growth factor expression in keloid fibroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid. Archives of dermatological research. vol 300. issue 4. 2008-07-01. PMID:18239926. |
pgc-vegf shrna 2 (short hairpin rna 2) plasmid significantly inhibited vegf expression determined by real-time polymerase chain reaction (pcr), enzyme-linked immunosorbent assay (elisa), and fibroblasts growth was also significantly by (methyl thiazolyl tetrazolium) mtt assay and apoptosis detection, whereas the control transfection showed no obviously effects. |
2008-07-01 |
2023-08-12 |
Not clear |
| Ping Sun, Jie Gao, Yan-Li Liu, Lu-Wan Wei, Li-Ping Wu, Zhi-Yu Li. RNA interference (RNAi)-mediated vascular endothelial growth factor-C (VEGF-C) reduction interferes with lymphangiogenesis and enhances epirubicin sensitivity of breast cancer cells. Molecular and cellular biochemistry. vol 308. issue 1-2. 2008-06-10. PMID:17938864. |
the sensitivity to anticancer agents was evaluated by mtt and apoptosis assay, and apoptosis-related genes bcl-2/bax ratio was determined by western blotting. |
2008-06-10 |
2023-08-12 |
human |
| Chuangying Hu, Liang Chen, Yong Jiang, Yi Li, Shaofeng Wan. The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells. Cancer biology & therapy. vol 7. issue 1. 2008-06-10. PMID:18059177. |
the changes of proliferation and apoptosis of hepatic cancer cell line hepg2 with facl4 protein expression were examined by mtt and flow cytometry respectively after facl4 selective inhibitor triacsin c treatment. |
2008-06-10 |
2023-08-12 |
human |
| Ni Sima, Wei Wang, Debo Kong, Dongrui Deng, Qian Xu, Jianfeng Zhou, Gang Xu, Li Meng, Yunping Lu, Shixuan Wang, Ding M. RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53. Apoptosis : an international journal on programmed cell death. vol 13. issue 2. 2008-06-03. PMID:18060502. |
hpv16-transformed siha and caski cells were used as a model system; rt-pcr, western blotting, mtt assay, tunel staining, annexin v apoptosis assay and flow cytometry were applied to examine the effects of psiren-16e7. |
2008-06-03 |
2023-08-12 |
human |