| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Lee, J H Park, M H Yan. The effect of cyclophosphamide on Fas-mediated apoptosis. Journal of Korean medical science. vol 12. issue 3. 1997-10-23. PMID:9250912. |
fas is a cell surface protein that can mediate apoptosis and belongs to the tumor necrosis factor (tnf) receptor family. |
1997-10-23 |
2023-08-12 |
human |
| J H Lee, J H Park, M H Yan. The effect of cyclophosphamide on Fas-mediated apoptosis. Journal of Korean medical science. vol 12. issue 3. 1997-10-23. PMID:9250912. |
because many chemotherapeutic drugs are capable of initiating pathways leading to apoptosis, we determined the effect of cyclophosphamide, one of the most widely used anticancer drugs, on fas mediated apoptosis in human lymphoma cell lines; skw6.4 and jurkat. |
1997-10-23 |
2023-08-12 |
human |
| J H Lee, J H Park, M H Yan. The effect of cyclophosphamide on Fas-mediated apoptosis. Journal of Korean medical science. vol 12. issue 3. 1997-10-23. PMID:9250912. |
apoptosis was measured by electrophoresis of dna fragmentation and surface expression of fas was measured by flow cytometry. |
1997-10-23 |
2023-08-12 |
human |
| J H Lee, J H Park, M H Yan. The effect of cyclophosphamide on Fas-mediated apoptosis. Journal of Korean medical science. vol 12. issue 3. 1997-10-23. PMID:9250912. |
these results suggested that the anti-cancer drug might be mediated via the pathway of fas mediated apoptosis in the lymphoma cell lines. |
1997-10-23 |
2023-08-12 |
human |
| J B Mannick, X Q Miao, J S Stamle. Nitric oxide inhibits Fas-induced apoptosis. The Journal of biological chemistry. vol 272. issue 39. 1997-10-23. PMID:9305857. |
the fas antigen (cd95, apo-1) is a transmembrane cell surface receptor that mediates apoptosis of many cell types when bound by fas ligand or cross-linked by agonist antibody. |
1997-10-23 |
2023-08-12 |
human |
| G C Tsokos, B Kovacs, S N Liossi. Lymphocytes, cytokines, inflammation, and immune trafficking. Current opinion in rheumatology. vol 9. issue 5. 1997-10-23. PMID:9309192. |
only occasionally do lupus patients display structural defects of either fas antigen or ligand molecules, and although spontaneous apoptosis is increased in lupus cells (as well as in other systemic autoimmune disorders), the activation-induced t-cell death is defective. |
1997-10-23 |
2023-08-12 |
Not clear |
| K Antoku, Z Liu, D E Johnso. Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents. Leukemia. vol 11. issue 10. 1997-10-23. PMID:9324287. |
proteases that are members of the caspase (or interleukin-1beta converting enzyme (ice)) protease family have been shown to be important mediators of apoptosis induced by fas activation, neurotrophic factor withdrawal, and detachment from extracellular matrix. |
1997-10-23 |
2023-08-12 |
human |
| C C Anderson, R Mukherjee, N R Sinclair, A M Jevnika. Hypogammaglobulinaemia occurs in Fas-deficient MRL-lpr mice following deletion of MHC class II molecules. Clinical and experimental immunology. vol 109. issue 3. 1997-10-23. PMID:9328125. |
fas (cd95)-mediated apoptosis in b and t cells is deficient in both human autoimmune lymphoproliferative syndrome and in mrl-lpr mice, a model for systemic lupus erythematosis (sle). |
1997-10-23 |
2023-08-12 |
mouse |
| H Waldner, R A Sobel, E Howard, V K Kuchro. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 7. 1997-10-21. PMID:9317104. |
compared with wild-type mice, mice expressing lpr (fas) and gld (fasl) mutations were relatively resistant to the development of clinical eae, and this correlated with fewer inflammatory infiltrates and cells undergoing apoptosis in the cns of the mutant mice. |
1997-10-21 |
2023-08-12 |
mouse |
| A Brás, C Martinez-A, E Baixera. B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 7. 1997-10-21. PMID:9317114. |
apoptosis induced by fas ligation is consequently abrogated after sigg engagement, and sigg signaling therefore interferes with the apoptotic signal upstream of ice protease activation. |
1997-10-21 |
2023-08-12 |
Not clear |
| J W Lee, G M Gersuk, P A Kiener, C Beckham, J A Ledbetter, H J Dee. HLA-DR-triggered inhibition of hemopoiesis involves Fas/Fas ligand interactions and is prevented by c-kit ligand. Journal of immunology (Baltimore, Md. : 1950). vol 159. issue 7. 1997-10-21. PMID:9317119. |
the addition of fas-ig, a fusion protein that neutralizes fas ligand (fas-l), also prevented mab h81.9-induced apoptosis. |
1997-10-21 |
2023-08-12 |
human |
| O W Rokhlin, B S Hostager, G A Bishop, S P Sidorenko, R A Glover, A V Gudkov, M B Cohe. Dominant nature of the resistance to Fas- and tumor necrosis factor-alpha-mediated apoptosis in human prostatic carcinoma cell lines. Cancer research. vol 57. issue 18. 1997-10-20. PMID:9307276. |
we have recently found (o. w. rokhlin et al., cancer res., 57: 1758-1768, 1997) that, although fas ligation induced apoptosis in two of six human prostatic carcinoma cell lines investigated, the apoptotic machinery involved in fas-mediated killing is already in place in fas-resistant cell lines. |
1997-10-20 |
2023-08-12 |
human |
| A Inukai, G Sobu. [Apoptosis and myopathies]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256007. |
in an attempt to determine whether the fas-fas-ligand mediated apoptosis operates in the pathologic process of human myopathies, we examined the expression of fas antigen, the synthesis of fas-ligand mrna, and the presence of chromosomal dna fragmentation in the muscles from patients with various human muscle disorders. |
1997-10-17 |
2023-08-12 |
human |
| A Inukai, G Sobu. [Apoptosis and myopathies]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256007. |
our data suggest that the expression of fas antigen on muscle fibers in diseased muscles might be related to unknown biological functions other than "apoptosis" in the process of muscle fiber injury. |
1997-10-17 |
2023-08-12 |
human |
| Y Matsumoto, T Shinzato, I Amano, K Maed. [Apoptosis in uremic complication]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256009. |
to elucidate the involvement of apoptosis in these complications, we analyzed fas antigen which mediates apoptosis on peripheral blood t cells and hepatic cells. |
1997-10-17 |
2023-08-12 |
Not clear |
| Y Matsumoto, T Shinzato, I Amano, K Maed. [Apoptosis in uremic complication]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256009. |
when cultured in vitro, uremic t cells were shown to undergo acceleratd apoptosis in correlation with fas expression. |
1997-10-17 |
2023-08-12 |
Not clear |
| Y Matsumoto, T Shinzato, I Amano, K Maed. [Apoptosis in uremic complication]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256009. |
these results suggest that t cells and hepatocytes in crf may undergo apoptosis by the fas system. |
1997-10-17 |
2023-08-12 |
Not clear |
| N Ogawa, H Ohash. [Study of apoptosis in Sjögren's syndrome]. Rinsho byori. The Japanese journal of clinical pathology. vol 45. issue 7. 1997-10-17. PMID:9256010. |
in pbl, ss t lymphocytes showed accelerated in vitro apoptosis, and cd4+ t cells showed increased fas expression compared to those in normal controls. |
1997-10-17 |
2023-08-12 |
Not clear |
| N Hagimoto, K Kuwano, H Miyazaki, R Kunitake, M Fujita, M Kawasaki, Y Kaneko, N Har. Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. American journal of respiratory cell and molecular biology. vol 17. issue 3. 1997-10-17. PMID:9308912. |
induction of apoptosis and pulmonary fibrosis in mice in response to ligation of fas antigen. |
1997-10-17 |
2023-08-12 |
mouse |
| N Hagimoto, K Kuwano, H Miyazaki, R Kunitake, M Fujita, M Kawasaki, Y Kaneko, N Har. Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. American journal of respiratory cell and molecular biology. vol 17. issue 3. 1997-10-17. PMID:9308912. |
fas antigen is a cell surface protein that mediates apoptosis, and it is expressed in various cells and tissues. |
1997-10-17 |
2023-08-12 |
mouse |