| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Luo, Hehe Liu, Jiwen Wang, Liang Li, Chunchun Han, Xinmeng Gan, Yanying Li, Lili Bai, Ahsan Mustaf. Transcriptome reveals B lymphocyte apoptosis in duck embryonic bursa of Fabricius mediated by mitochondrial and Fas signaling pathways. Molecular immunology. vol 101. 2019-03-25. PMID:29933212. |
transcriptome reveals b lymphocyte apoptosis in duck embryonic bursa of fabricius mediated by mitochondrial and fas signaling pathways. |
2019-03-25 |
2023-08-13 |
Not clear |
| Jun Luo, Hehe Liu, Jiwen Wang, Liang Li, Chunchun Han, Xinmeng Gan, Yanying Li, Lili Bai, Ahsan Mustaf. Transcriptome reveals B lymphocyte apoptosis in duck embryonic bursa of Fabricius mediated by mitochondrial and Fas signaling pathways. Molecular immunology. vol 101. 2019-03-25. PMID:29933212. |
by performing enrichment analysis for degs and qrt-pcr, our results demonstrated that both mitochondrial and fas signaling pathways mediated bursal b-cell apoptosis during the duck embryonic development. |
2019-03-25 |
2023-08-13 |
Not clear |
| Jun Luo, Hehe Liu, Jiwen Wang, Liang Li, Chunchun Han, Xinmeng Gan, Yanying Li, Lili Bai, Ahsan Mustaf. Transcriptome reveals B lymphocyte apoptosis in duck embryonic bursa of Fabricius mediated by mitochondrial and Fas signaling pathways. Molecular immunology. vol 101. 2019-03-25. PMID:29933212. |
overall, these data demonstrated that from ed14-ed22, apoptosis of bursal b-cells was mediated by mitochondrial and fas signaling pathways and could be regulated by bmp4, foxo1 and igf-1 in duck. |
2019-03-25 |
2023-08-13 |
Not clear |
| Yi Liu, Xiaoxv Dong, Wenping Wang, Longtai You, Xingbin Yin, Chunjing Yang, Na Sai, Xin Leng, Jian N. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins. vol 10. issue 5. 2019-03-19. PMID:29762502. |
molecular mechanisms of apoptosis in heparg cell line induced by polyphyllin vi via the fas death pathway and mitochondrial-dependent pathway. |
2019-03-19 |
2023-08-13 |
Not clear |
| Yuanzheng Yang, Gangxiong Huang, Zhichao Zhou, Jason G Fewell, Eugenie S Kleinerma. miR-20a Regulates FAS Expression in Osteosarcoma Cells by Modulating Molecular cancer therapeutics. vol 17. issue 1. 2019-03-05. PMID:29079708. |
downregulation of fas allows osteosarcoma cells to escape fas ligand-mediated apoptosis when they enter a fas ligand-positive microenvironment such as the lung. |
2019-03-05 |
2023-08-13 |
Not clear |
| Fei Yi, Nicholas Frazzette, Anthony C Cruz, Christopher A Klebanoff, Richard M Siege. Beyond Cell Death: New Functions for TNF Family Cytokines in Autoimmunity and Tumor Immunotherapy. Trends in molecular medicine. vol 24. issue 7. 2019-03-04. PMID:29880309. |
originally discovered as an inducer of apoptosis, the tnf-family receptor fas (cd95, apo-1, tnfrsf6) has more recently been found to have functions beyond cell death, including t cell co-stimulation and promoting terminal differentiation of cd4 |
2019-03-04 |
2023-08-13 |
Not clear |
| Harun Basoglu, Beyza Goncu, Fahri Akba. Magnetic nanoparticle-mediated gene therapy to induce Fas apoptosis pathway in breast cancer. Cancer gene therapy. vol 25. issue 5-6. 2019-02-28. PMID:29593359. |
magnetic nanoparticle-mediated gene therapy to induce fas apoptosis pathway in breast cancer. |
2019-02-28 |
2023-08-13 |
human |
| Nazem El Husseini, Barbara F Hale. The Roles of P53 and Its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis-Stage Mouse Embryos. Toxicological sciences : an official journal of the Society of Toxicology. vol 162. issue 2. 2019-02-25. PMID:29228353. |
upregulation of the expression of genes that regulate cell cycle arrest and apoptosis, cdkn1a, rb1, fas, trp53inp1, and pmaip1, was p53-dependent in hydroxyurea-treated embryos. |
2019-02-25 |
2023-08-13 |
mouse |
| Zhengrong Xu, Tao Li, Man Li, Lei Yang, Rudan Xiao, Li Liu, Xin Chi, Dianwu Li. eRF3b-37 inhibits the TGF-β1-induced activation of hepatic stellate cells by regulating cell proliferation, G0/G1 arrest, apoptosis and migration. International journal of molecular medicine. vol 42. issue 6. 2019-02-25. PMID:30272252. |
the increased mrna and protein expression of the pro‑fibrogenic factors collagen i, connective tissue growth factor and α‑smooth muscle actin (sma) stimulated by tgf‑β1 were reduced by erf3b‑37 via the following mechanisms: i) inhibiting lx‑2 cell proliferation, leading to g0/g1 cell cycle arrest and inhibition of dna synthesis by downregulating the mrna expressions of cyclin d1 and cyclin dependent kinase‑4, and upregulating the levels of p21; ii) increasing cell apoptosis by upregulating the mrna level of b‑cell lymphoma-2 (bcl‑2)‑associated x protein (bax) and fas, and downregulating the expression of bcl‑2; and iii) reducing cell migration by downregulating the mrna and protein expression of α‑sma. |
2019-02-25 |
2023-08-13 |
mouse |
| Hua Tian, Shu-Tong Yao, Na-Na Yang, Jie Ren, Peng Jiao, Xiangjian Zhang, Dong-Xuan Li, Gong-An Zhang, Zhen-Fang Xia, Shu-Cun Qi. D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway. Scientific reports. vol 7. issue 1. 2019-02-21. PMID:28779128. |
our results showed that ox-ldl induced apoptosis, nf-κb p65 nuclear translocation and the upregulation of fas/fasl pathway-related proteins, including fas, fasl, fas-associated death domain proteins (fadd), caspase-8 and caspase-3 in raw264.7 macrophages, whereas silencing of fas blocked ox-ldl-induced macrophage apoptosis. |
2019-02-21 |
2023-08-13 |
Not clear |
| Hua Tian, Shu-Tong Yao, Na-Na Yang, Jie Ren, Peng Jiao, Xiangjian Zhang, Dong-Xuan Li, Gong-An Zhang, Zhen-Fang Xia, Shu-Cun Qi. D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway. Scientific reports. vol 7. issue 1. 2019-02-21. PMID:28779128. |
furthermore, silencing of p65 attenuated macrophage apoptosis and the upregulation of fas caused by ox-ldl, whereas p65 expression was not significantly affected by treatment with fas sirna. |
2019-02-21 |
2023-08-13 |
Not clear |
| Anna Malyshkina, Elisabeth Littwitz-Salomon, Kathrin Sutter, Gennadiy Zelinskyy, Sonja Windmann, Simone Schimmer, Annette Paschen, Hendrik Streeck, Kim J Hasenkrug, Ulf Dittme. Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection. Scientific reports. vol 7. issue 1. 2019-02-21. PMID:28798348. |
during chronic fv infection a population of activated fv-specific cd4+ t cells did not express cytotoxic molecules, but fas ligand that can induce fas-induced apoptosis in target cells. |
2019-02-21 |
2023-08-13 |
mouse |
| Jung Yoon Jang, Yong Jung Kang, Bokyung Sung, Min Jeong Kim, Chaeun Park, Dongwan Kang, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Ki. MHY440, a Novel Topoisomerase Ι Inhibitor, Induces Cell Cycle Arrest and Apoptosis via a ROS-Dependent DNA Damage Signaling Pathway in AGS Human Gastric Cancer Cells. Molecules (Basel, Switzerland). vol 24. issue 1. 2019-02-21. PMID:30597845. |
mhy440 induced ags cell apoptosis through the upregulation of fas-l, fas, and bax as well as the proteolysis of bh3 interacting-domain death agonist and poly(adp-ribose) polymerase. |
2019-02-21 |
2023-08-13 |
human |
| Chuan Sun, Huibin Liu, Jing Guo, Yang Yu, Di Yang, Fang He, Zhimin D. MicroRNA-98 negatively regulates myocardial infarction-induced apoptosis by down-regulating Fas and caspase-3. Scientific reports. vol 7. issue 1. 2019-02-19. PMID:28784995. |
microrna-98 negatively regulates myocardial infarction-induced apoptosis by down-regulating fas and caspase-3. |
2019-02-19 |
2023-08-13 |
mouse |
| Zhao Zhang, Hua-Jun Yu, Hui Huang, Hua-Hua Wang, Shang Wu, Hai-Yang Liu, Hai-Tao Zhan. The photodynamic activity and toxicity evaluation of 5,10,15-tris(ethoxylcarbonyl)corrole phosphorus(V) in vivo and in vitro. European journal of medicinal chemistry. vol 163. 2019-02-11. PMID:30579120. |
in addition, the potential anti-tumour mechanism study of 1-p was also investigated by the apoptosis antibody array, immunohistochemical and western blotting assay (wb) experiments, we found that the pdt activity of 1-p can degrade sirt1 (an important deacetylase), and activate the fas signal pathway to inhibit the growth of liver cancer cells. |
2019-02-11 |
2023-08-13 |
Not clear |
| Sailaja Polavarapu, Bilikere S Dwarakanath, Undurti N Da. Arachidonic acid activates extrinsic apoptotic pathway to enhance tumoricidal action of bleomycin against IMR-32 cells. Prostaglandins, leukotrienes, and essential fatty acids. vol 132. 2019-02-06. PMID:29735018. |
our current study revealed that a combination of bleomycin and aa significantly enhanced the expression of fas gene, which is involved in programmed cell death (apoptosis) and caspases 3 and 8 compared to either bleomycin or aa alone implying that activation of extrinsic apoptotic pathway plays a major role in their (bleomycin + aa) tumoricidal action. |
2019-02-06 |
2023-08-13 |
human |
| Lu Kong, Wangcheng Hu, Chuncheng Lu, Keping Cheng, Meng Tan. Mechanisms underlying nickel nanoparticle induced reproductive toxicity and chemo-protective effects of vitamin C in male rats. Chemosphere. vol 218. 2019-02-06. PMID:30472609. |
the cellular apoptosis might be induced by caspase family proteinases, but the regulator factor (factor associated suicide (fas), b-cell lymphoma-2 (bcl-2), bax, bh3-interacting domain death agonist (bid) and aif protein) might not be involved in this process. |
2019-02-06 |
2023-08-13 |
rat |
| Xiaoqing Liu, Dwayne M Hansen, Noah J Timko, Ziwen Zhu, Andrew Ames, Chenglu Qin, Michael B Nicholl, Qian Bai, Xuhui Chen, Mark R Wakefield, Gage West, Yujiang Fan. Association between interleukin‑33 and ovarian cancer. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30535474. |
therefore, il‑33 promoted proliferation and inhibited apoptosis of ovarian cancer cells by downregulation of p27, fas and trailr1. |
2019-02-04 |
2023-08-13 |
Not clear |
| Dirk Theile, Gerd Miku. Methadone against cancer: Lost in translation. International journal of cancer. vol 143. issue 8. 2019-01-25. PMID:29516505. |
finally, the receptors mostly responsible for induction of apoptosis by d,l-methadone remain unclear as contributions of both µ-opioid receptors, fas cell death receptors, toll-like receptors, n-methyl-d-aspartate receptors and opioid growth factor receptors were suggested. |
2019-01-25 |
2023-08-13 |
Not clear |
| Sona Margaryan, Agata Witkowicz, Arsen Arakelyan, Anna Partyka, Lidia Karabon, Gayane Manukya. sFasL-mediated induction of neutrophil activation in patients with type 2 diabetes mellitus. PloS one. vol 13. issue 7. 2019-01-17. PMID:30024959. |
activation of caspase-1 activity abolished sfasl-dependent apoptosis, and suppressed fas expression and mrna levels of caspase-3 in neutrophils from t2dm patients. |
2019-01-17 |
2023-08-13 |
Not clear |