| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingjing Zhu, Pierre-Florent Petit, Benoit J Van den Eynd. Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism. Cancer immunology, immunotherapy : CII. vol 68. issue 5. 2019-05-22. PMID:30406374. |
fas-mediated apoptosis of t cells has long been known as a mechanism allowing the contraction of t-cell responses to prevent immunopathology, a phenomenon known as activation-induced cell death, which is triggered by induction of fas ligand (fasl) expression on t cells themselves and qualifies as an immune checkpoint mechanism. |
2019-05-22 |
2023-08-13 |
Not clear |
| Mingcheng Cai, Yongsong Hu, Tianhao Zheng, Hongbing He, Wudian Xiao, Buwei Liu, Yu Shi, Xianbo Jia, Shiyi Chen, Jie Wang, Songjia La. MicroRNA-216b inhibits heat stress-induced cell apoptosis by targeting Fas in bovine mammary epithelial cells. Cell stress & chaperones. vol 23. issue 5. 2019-05-21. PMID:29730848. |
microrna-216b inhibits heat stress-induced cell apoptosis by targeting fas in bovine mammary epithelial cells. |
2019-05-21 |
2023-08-13 |
cattle |
| Mingcheng Cai, Yongsong Hu, Tianhao Zheng, Hongbing He, Wudian Xiao, Buwei Liu, Yu Shi, Xianbo Jia, Shiyi Chen, Jie Wang, Songjia La. MicroRNA-216b inhibits heat stress-induced cell apoptosis by targeting Fas in bovine mammary epithelial cells. Cell stress & chaperones. vol 23. issue 5. 2019-05-21. PMID:29730848. |
finally, inhibition of fas via the small interfering rna (sirna) also inhibited cell apoptosis induced by heat stress. |
2019-05-21 |
2023-08-13 |
cattle |
| Meina Lin, Ruiyuan Xu, Tao Zhang, Lin Zhang, Xuqiao Me. [Expression of c-FLIP in peripheral blood mononuclear cells of patients with rheumatoid arthritis and its relation with extrinsic apoptotic pathway]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 47. issue 4. 2019-05-21. PMID:30511525. |
to investigate the expression of apoptosis related protein cellular fas associated death domain like interleukin 1 converting enzyme inhibitory protein (c-flip) in peripheral blood mononuclear cells (pbmcs) of patients with rheumatoid arthritis and its relation with extrinsic apoptotic pathway. |
2019-05-21 |
2023-08-13 |
Not clear |
| Katrin A Salva, Youn H Kim, Ziba Rahbar, Gary S Woo. Epigenetically Enhanced PDT Induces Significantly Higher Levels of Multiple Extrinsic Pathway Apoptotic Factors than Standard PDT, Resulting in Greater Extrinsic and Overall Apoptosis of Cutaneous T-cell Lymphoma. Photochemistry and photobiology. vol 94. issue 5. 2019-05-14. PMID:29675945. |
we have previously demonstrated that the resistance of ctcl to apoptosis correlates with decreased expression of death receptors such as fas, and that methotrexate functions as an epigenetic regulator that reestablishes the susceptibility of ctcl to extrinsic pathway apoptosis. |
2019-05-14 |
2023-08-13 |
Not clear |
| Laura J Adkins, Caitlyn T Molloy, Jason B Weinber. Fas activity mediates airway inflammation during mouse adenovirus type 1 respiratory infection. Virology. vol 521. 2019-05-13. PMID:29908447. |
virus-induced apoptosis in lungs was not affected by fas deficiency. |
2019-05-13 |
2023-08-13 |
mouse |
| Devon M Headen, Kyle B Woodward, María M Coronel, Pradeep Shrestha, Jessica D Weaver, Hong Zhao, Min Tan, Michael D Hunckler, William S Bowen, Christopher T Johnson, Lonnie Shea, Esma S Yolcu, Andrés J García, Haval Shirwa. Local immunomodulation Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance. Nature materials. vol 17. issue 8. 2019-05-10. PMID:29867165. |
t effector cells are responsible for islet allograft rejection and express fas death receptors following activation, becoming sensitive to fas-mediated apoptosis. |
2019-05-10 |
2023-08-13 |
mouse |
| Viviana Blank, Yanina Bellizzi, Elsa Zotta, Patricia G Cornier, Carina M L Delpiccolo, Dora B Boggián, Ernesto G Mata, Leonor P Rogui. A novel penicillin derivative induces antitumor effect in melanoma cells. Anti-cancer drugs. vol 29. issue 5. 2019-05-08. PMID:29494356. |
apoptosis in vivo was assessed by detecting active caspase-3 in tumor slices from treated mice and the expression levels of fas, trail, and bcl-2 proteins in tumor lysates. |
2019-05-08 |
2023-08-13 |
mouse |
| Po-Kai Chuang, Michael Hsiao, Tsui-Ling Hsu, Chuan-Fa Chang, Chung-Yi Wu, Bo-Rui Chen, Han-Wen Huang, Kuo-Shiang Liao, Chen-Chun Chen, Chi-Long Chen, Shun-Min Yang, Chiung Wen Kuo, Peilin Chen, Ping-Tzu Chiu, I-Ju Chen, Jiann-Shiun Lai, Cheng-Der Tony Yu, Chi-Huey Won. Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 9. 2019-05-02. PMID:30808745. |
knockdown of β3galt5 disrupts the complex and induces apoptosis through dissociation of rip from the complex to interact with the fas death domain (fadd) and trigger the fas-dependent pathway. |
2019-05-02 |
2023-08-13 |
Not clear |
| Guodong Cai, Mengxue Si, Xi Li, Hui Zou, Jianhong Gu, Yan Yuan, Xuezhong Liu, Zongping Liu, Jianchun Bia. Zearalenone induces apoptosis of rat Sertoli cells through Fas-Fas ligand and mitochondrial pathway. Environmental toxicology. vol 34. issue 4. 2019-04-22. PMID:30600648. |
the results revealed that zea induced apoptosis of rat sertoli cells, significantly reduced the transcription and expression of the anti-apoptotic protein bcl-2, increased the transcription and expression of pro-apoptotic proteins bax and tbid, and fas, fasl, fadd, and caspase-8. |
2019-04-22 |
2023-08-13 |
rat |
| You-Cheng Hseu, Yi-Chun Shen, Ming-Ching Kao, Dony Chacko Mathew, Palaniyandi Karuppaiya, Mei-Ling Li, Hsin-Ling Yan. Ganoderma tsugae induced ROS-independent apoptosis and cytoprotective autophagy in human chronic myeloid leukemia cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 124. 2019-04-18. PMID:30465897. |
in addition, gt induced mitochondrial and death receptor mediated apoptosis, correlated with dna fragmentation, followed by cytochrome c release, caspase-3/8/9 activation, parp cleavage, fas activation, bid cleavage, and bax/bcl-2 dysregulation. |
2019-04-18 |
2023-08-13 |
human |
| Pei-Jun Ni, Lin Feng, Wei-Dan Jiang, Pei Wu, Yang Liu, Jun Jiang, Sheng-Yao Kuang, Ling Tang, Wu-Neng Tang, Xiao-Qiu Zho. Impairing of gill health through decreasing immune function and structural integrity of grass carp (Ctenopharyngodon idella) fed graded levels dietary lipids after challenged with Flavobacterium columnare. Fish & shellfish immunology. vol 86. 2019-04-16. PMID:30590156. |
in addition, low or excess levels of lipids decreased young grass carp physical barrier function through down-regulating the mrna levels of zo-1 (rather than zo-2b), claudin b, c, 3, 12, 15a, 15b, 7b, 7a and occludin through mapkk 6/p38 mapk/mlck signaling molecules, decreasing antioxidant ability via kelch-like ech-associating protein 1a (keap1a)/nf-e2-related factor 2 (nrf2) signaling molecules, and down-regulating the mrna levels of b-cell lymphoma-2 (bcl-2) and inhibitor of apoptosis protein (iap) and up-regulating the mrna levels of apoptotic protease activating factor-1 (apaf-1), caspase-3, -8 and -9 and fas ligand (fasl) in the gill of grass carp. |
2019-04-16 |
2023-08-13 |
Not clear |
| Antonella Santillo, Lucia Figliola, Mariangela Caroprese, Rosaria Marino, Maria dʼApolito, Ida Giardino, Marzia Albenzi. Effect of lipid fraction of digested milk from different sources in mature 3T3-L1 adipocyte. The Journal of dairy research. vol 86. issue 1. 2019-04-15. PMID:30729901. |
cellular viability, apoptosis, oxidative response and gene expression levels of nf-κb p65, hmgb1, srebp-1c and fas were evaluated. |
2019-04-15 |
2023-08-13 |
human |
| Kai Liu, Huichu Ye, Jin Zhou, Yue Tian, Hufeng Xu, Xuelian Sun, Dong Zhan. Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells. International immunopharmacology. vol 65. 2019-04-08. PMID:30268799. |
this suppression decline was caused by effects of ox40 on proliferation and apoptosis independent of perforin, granzyme b and fas ligand. |
2019-04-08 |
2023-08-13 |
Not clear |
| Tobias Boch, Thomas Luft, Georgia Metzgeroth, Maximilian Mossner, Johann-Christoph Jann, Daniel Nowak, Franziska La Meir, Christiane Schumann, Jennifer Klemmer, Susanne Brendel, Harald Fricke, Claudia Kunz, Christel Weiß, Wolf-Karsten Hofmann, Florian Nolt. Safety and efficacy of the CD95-ligand inhibitor asunercept in transfusion-dependent patients with low and intermediate risk MDS. Leukemia research. vol 68. 2019-04-05. PMID:29549809. |
in low risk mds, increased apoptosis of erythroid progenitors mediated via cd95 (fas) activation has been described to result in peripheral cytopenia. |
2019-04-05 |
2023-08-13 |
human |
| Michael J Berridg. Lymphocyte Activation in Health and Disease. Critical reviews in immunology. vol 37. issue 2-6. 2019-04-05. PMID:29773029. |
the il-2 and fas receptors employ additional signaling cassettes (e.g., the jak/stat and the sphingomyelinase/ceramide pathways) to mediate their effects on proliferation and apoptosis, respectively. |
2019-04-05 |
2023-08-13 |
human |
| Lukasz Szymanski, Aleksandra Cios, Sławomir Lewicki, Pawel Szymanski, Wanda Stankiewic. Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field. PloS one. vol 13. issue 10. 2019-04-03. PMID:30286163. |
for example, activation of the fas (cd95)/fasl (cd178) pathway in ad does not lead to extensive apoptosis in skin. |
2019-04-03 |
2023-08-13 |
Not clear |
| Lukasz Szymanski, Aleksandra Cios, Sławomir Lewicki, Pawel Szymanski, Wanda Stankiewic. Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field. PloS one. vol 13. issue 10. 2019-04-03. PMID:30286163. |
binding of the fas receptor to its protein ligand-fasl, which are present on the (ad)-modified keratinocytes, should result in the sequential induction of cell death, but there is no evidence of extensive apoptosis of these cells. |
2019-04-03 |
2023-08-13 |
Not clear |
| C L Guo, Y M Bi, Z Liu, Y Xu, Y X Sun, Q C Wan. [Elevated Fas expression is related to increased apoptosis of circulating CD8(+)T cell in patients with hepatocellular carcinoma]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 26. issue 2. 2019-04-01. PMID:29804379. |
[elevated fas expression is related to increased apoptosis of circulating cd8(+)t cell in patients with hepatocellular carcinoma]. |
2019-04-01 |
2023-08-13 |
Not clear |
| H W Wu, K Li, Y L Zeng, Y Kang, J P Liu, H B Ning, J Shan. [Influence of hepatitis B virus X gene on apoptosis of hepatic cells mediated by Fas]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 25. issue 6. 2019-03-27. PMID:28763859. |
[influence of hepatitis b virus x gene on apoptosis of hepatic cells mediated by fas]. |
2019-03-27 |
2023-08-13 |
Not clear |