| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Moreau, M Leite-De-Moraes, S Ezine, J P Di Santo, M Dy, E Schneide. Natural killer cell-dependent apoptosis of peripheral murine hematopoietic progenitor cells in response to Fas cross-linking: involvement of tumor necrosis factor-alpha. Blood. vol 97. issue 10. 2001-06-14. PMID:11342432. |
natural killer cell-dependent apoptosis of peripheral murine hematopoietic progenitor cells in response to fas cross-linking: involvement of tumor necrosis factor-alpha. |
2001-06-14 |
2023-08-12 |
mouse |
| U Lopatin, X Yao, R K Williams, J J Bleesing, J K Dale, D Wong, J Teruya-Feldstein, S Fritz, M R Morrow, I Fuss, M C Sneller, M Raffeld, T A Fleisher, J M Puck, W Strober, E S Jaffe, S E Strau. Increases in circulating and lymphoid tissue interleukin-10 in autoimmune lymphoproliferative syndrome are associated with disease expression. Blood. vol 97. issue 10. 2001-06-14. PMID:11342444. |
autoimmune lymphoproliferative syndrome (alps) is an inherited disorder in which genetic defects in proteins that mediate lymphocyte apoptosis, most often fas, are associated with enlargement of lymph nodes and the spleen and a variety of autoimmune manifestations. |
2001-06-14 |
2023-08-12 |
Not clear |
| E A Lafleur, S F Jia, L L Worth, Z Zhou, L B Owen-Schaub, E S Kleinerma. Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells. Cancer research. vol 61. issue 10. 2001-06-14. PMID:11358827. |
expression of fas (cd95, apo-1), a cell surface receptor capable of inducing ligand-mediated apoptosis, is involved in tissue homeostasis and elimination of targeted cells by natural killer and t cells. |
2001-06-14 |
2023-08-12 |
mouse |
| J Estaquier, V Monceaux, M C Cumont, A M Aubertin, B Hurtrel, J C Ameise. Early changes in peripheral blood T cells during primary infection of rhesus macaques with a pathogenic SIV. Journal of medical primatology. vol 29. issue 3-4. 2001-06-07. PMID:11085574. |
the primary phase of infection was associated with changes in the t cells expressing cd25, cd69, or hla-dr and with a priming of the peripheral blood cd4 and cd8 t cells for a process of apoptosis in vitro that was enhanced by cd95 (fas) ligation, and was detected in two macaques as early as 7 days after infection. |
2001-06-07 |
2023-08-12 |
Not clear |
| P Contini, M Ghio, A Merlo, S Brenci, G Filaci, F Indiveri, F Pupp. Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction. Human immunology. vol 61. issue 12. 2001-06-07. PMID:11163092. |
in the present study, we report that allogeneic soluble hla class i (shla-i) molecules isolated from serum induce apoptosis on ebv-specific cd8(+) fas(+) cytotoxic t lymphocytes (ctl). |
2001-06-07 |
2023-08-12 |
Not clear |
| P Contini, M Ghio, A Merlo, S Brenci, G Filaci, F Indiveri, F Pupp. Soluble HLA class I/CD8 ligation triggers apoptosis in EBV-specific CD8+ cytotoxic T lymphocytes by Fas/Fas-ligand interaction. Human immunology. vol 61. issue 12. 2001-06-07. PMID:11163092. |
apoptosis is triggered by the interaction of fas(+) ctl with soluble fas-ligand, which is released following the binding of shla-i antigens to cd8 molecules. |
2001-06-07 |
2023-08-12 |
Not clear |
| A Bhoumik, V Ivanov, Z Rona. Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 7. issue 2. 2001-06-07. PMID:11234888. |
the ability of the peptide to increase apoptosis coincided with increased cell surface expression of fas, which is the primary death-signaling cascade in these late-stage melanoma cells. |
2001-06-07 |
2023-08-12 |
human |
| F J Northington, D M Ferriero, D L Flock, L J Marti. Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 6. 2001-06-07. PMID:11245678. |
increased levels of fas death receptor, bax, and cytochrome c, activation of caspase 8, and abnormalities in mitochondria in the thalamus significantly precede the activation of caspase 3 and the appearance of neuronal apoptosis at 24 hr. |
2001-06-07 |
2023-08-12 |
rat |
| R Geleziunas, W Xu, K Takeda, H Ichijo, W C Green. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature. vol 410. issue 6830. 2001-06-07. PMID:11298454. |
as hiv-1 also enhances fas expression on virally infected cells, it is unclear how these hosts avoid rapid cell-autonomous apoptosis mediated through cis ligation of fas by fasl. |
2001-06-07 |
2023-08-12 |
human |
| R Geleziunas, W Xu, K Takeda, H Ichijo, W C Green. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature. vol 410. issue 6830. 2001-06-07. PMID:11298454. |
here we show that hiv-1 nef associates with and inhibits apoptosis signal-regulating kinase 1 (ask1), a serine/threonine kinase that forms a common and key signalling intermediate in the fas and tumour-necrosis factor-alpha (tnfalpha) death-signalling pathways. |
2001-06-07 |
2023-08-12 |
human |
| X M Wang, S F Yu, Z P Yan. Apoptosis of osteoclast-like cells induced by alendronate is related to Fas gene expression. The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA). vol 3. issue 2. 2001-06-07. PMID:11314515. |
apoptosis of osteoclast-like cells induced by alendronate is related to fas gene expression. |
2001-06-07 |
2023-08-12 |
Not clear |
| X M Wang, S F Yu, Z P Yan. Apoptosis of osteoclast-like cells induced by alendronate is related to Fas gene expression. The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA). vol 3. issue 2. 2001-06-07. PMID:11314515. |
to detect the mechanism of alendronate during inhibition of bone resorption by inducing apoptosis of osteoclasts and its relationship with the fas gene. |
2001-06-07 |
2023-08-12 |
Not clear |
| A Suliman, A Lam, R Datta, R K Srivastav. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways. Oncogene. vol 20. issue 17. 2001-06-07. PMID:11360196. |
these data suggest that death receptors (dr4 and dr5) and fas receptors induced apoptosis through identical signaling pathway, and trail-induced apoptosis via both mitochondrial-dependent and -independent pathways. |
2001-06-07 |
2023-08-12 |
Not clear |
| H G Burgert, J H Blusc. Immunomodulatory functions encoded by the E3 transcription unit of adenoviruses. Virus genes. vol 21. issue 1-2. 2001-05-31. PMID:11022786. |
the early transcription unit e3 of ads encodes proteins that inhibit antigen presentation by mhc class i molecules as well as apoptosis induced by tumor necrosis factor alpha (tnf-alpha) and fas ligand (fasl). |
2001-05-31 |
2023-08-12 |
human |
| G B Carey, D Donjerković, C M Mueller, S Liu, J A Hinshaw, L Tonnetti, W Davidson, D W Scot. B-cell receptor and Fas-mediated signals for life and death. Immunological reviews. vol 176. 2001-05-31. PMID:11043771. |
anti-mu-treated cells then undergo g1 arrest and die by apoptosis independent of fas. |
2001-05-31 |
2023-08-12 |
Not clear |
| T L Rothstein, X Zhong, B R Schram, R S Negm, T J Donohoe, D S Cabral, L C Foote, T J Schneide. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological reviews. vol 176. 2001-05-31. PMID:11043772. |
receptor-specific regulation of b-cell susceptibility to fas-mediated apoptosis and a novel fas apoptosis inhibitory molecule. |
2001-05-31 |
2023-08-12 |
Not clear |
| T L Rothstein, X Zhong, B R Schram, R S Negm, T J Donohoe, D S Cabral, L C Foote, T J Schneide. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological reviews. vol 176. 2001-05-31. PMID:11043772. |
the susceptibility of primary b cells to fas (apo-1, cd95)-mediated apoptosis is modulated by signals derived from additional surface receptors: cd40 engagement produces upregulation of fas expression and marked sensitivity to fas-induced cell death, whereas antigen receptor engagement, or interleukin-4 receptor (il-4r) engagement, inhibits fas killing and thereby produces fas resistance, even in otherwise susceptible, cd40-stimulated targets. |
2001-05-31 |
2023-08-12 |
Not clear |
| T L Rothstein, X Zhong, B R Schram, R S Negm, T J Donohoe, D S Cabral, L C Foote, T J Schneide. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological reviews. vol 176. 2001-05-31. PMID:11043772. |
proximate mediators for fas resistance include the known anti-apoptotic gene products bcl-xl and flip (but not btk), and a novel anti-apoptotic gene that encodes fas apoptosis inhibitory molecule (faim). |
2001-05-31 |
2023-08-12 |
Not clear |
| T L Rothstein, X Zhong, B R Schram, R S Negm, T J Donohoe, D S Cabral, L C Foote, T J Schneide. Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological reviews. vol 176. 2001-05-31. PMID:11043772. |
inducible resistance to fas-mediated apoptosis is speculated to protect antigen-specific b cells during potentially dangerous interactions with fasl-bearing t cells; the elevated sig-signaling threshold for inducible fas resistance in autoreactive, tolerant b cells would insure against autoimmunity. |
2001-05-31 |
2023-08-12 |
Not clear |
| D K Kim, E S Cho, J H Yoo, H D U. FLIP is constitutively hyperexpressed in Fas-resistant U266 myeloma cells, but is not induced by IL-6 in Fas-sensitive RPM18226 cells. Molecules and cells. vol 10. issue 5. 2001-05-31. PMID:11101147. |
despite the expression of fas, some clones of myeloma cells are resistant to fas-mediated apoptosis. |
2001-05-31 |
2023-08-12 |
Not clear |