| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang, R E Fischer, C E Jackson, A Y Lin, C Bäumler, E Siegert, A Marx, A K Vaishnaw, T Grodzicky, T A Fleisher, M J Lenard. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood. vol 98. issue 1. 2001-07-26. PMID:11418480. |
the development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline fas mutations and defective lymphocyte apoptosis. |
2001-07-26 |
2023-08-12 |
Not clear |
| S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang, R E Fischer, C E Jackson, A Y Lin, C Bäumler, E Siegert, A Marx, A K Vaishnaw, T Grodzicky, T A Fleisher, M J Lenard. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood. vol 98. issue 1. 2001-07-26. PMID:11418480. |
fas (cd95/apo-1) is a cell surface receptor that initiates programmed cell death, or apoptosis, of activated lymphocytes. |
2001-07-26 |
2023-08-12 |
Not clear |
| S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang, R E Fischer, C E Jackson, A Y Lin, C Bäumler, E Siegert, A Marx, A K Vaishnaw, T Grodzicky, T A Fleisher, M J Lenard. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood. vol 98. issue 1. 2001-07-26. PMID:11418480. |
lymphoma phenotype was determined by immunohistochemistry, frequency of cd3(+)cd4(-)cd8(-) t-cell-receptor alpha/beta cells by flow cytometry, nucleotide sequences of the gene encoding fas (apt1, tnfrsf6), and the percentage of lymphocytes undergoing apoptosis in vitro. |
2001-07-26 |
2023-08-12 |
Not clear |
| S E Straus, E S Jaffe, J M Puck, J K Dale, K B Elkon, A Rösen-Wolff, A M Peters, M C Sneller, C W Hallahan, J Wang, R E Fischer, C E Jackson, A Y Lin, C Bäumler, E Siegert, A Marx, A K Vaishnaw, T Grodzicky, T A Fleisher, M J Lenard. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood. vol 98. issue 1. 2001-07-26. PMID:11418480. |
investigation of these 10 patients and their relatives with fas mutations revealed that all had defective lymphocyte apoptosis and most had other features of alps. |
2001-07-26 |
2023-08-12 |
Not clear |
| S Urayama, A Kawakami, T Nakashima, S Yamasaki, A Hida, H Ida, M Kamachi, H Nakamura, T Origuchi, K Migita, Y Kawabe, K Eguch. New disease-modifying antirheumatic drug 2 acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid (KE-298) selectively augments activation-induced T cell death. The Journal of laboratory and clinical medicine. vol 138. issue 1. 2001-07-26. PMID:11433223. |
fas expression and caspase-3 activity in activated t cells were also examined by flow cytometry, and expression of fas ligand (fasl), bcl-2-related proteins, and x chromosome-linked inhibitor of apoptosis protein (xiap) was determined by western blot analysis. |
2001-07-26 |
2023-08-12 |
Not clear |
| E M Eves, C Skoczylas, K Yoshida, E S Alnemri, M R Rosne. FGF induces a switch in death receptor pathways in neuronal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 14. 2001-07-26. PMID:11438575. |
fgf suppresses the fas death pathway but also induces apoptosis by activation of a tnfalpha death pathway in both h19-7 and hippocampal progenitor cells. |
2001-07-26 |
2023-08-12 |
rat |
| D A Porter, R M Harman, R G Cowan, S M Quir. Relationship of Fas ligand expression and atresia during bovine follicle development. Reproduction (Cambridge, England). vol 121. issue 4. 2001-07-19. PMID:11277875. |
the fas antigen (fas) is a cell surface receptor that may be involved in the initiation and progression of follicle cell apoptosis during atresia. |
2001-07-19 |
2023-08-12 |
cattle |
| D A Porter, R M Harman, R G Cowan, S M Quir. Relationship of Fas ligand expression and atresia during bovine follicle development. Reproduction (Cambridge, England). vol 121. issue 4. 2001-07-19. PMID:11277875. |
fas initiates apoptosis in sensitive cells after binding fas ligand (fasl). |
2001-07-19 |
2023-08-12 |
cattle |
| D A Porter, R M Harman, R G Cowan, S M Quir. Relationship of Fas ligand expression and atresia during bovine follicle development. Reproduction (Cambridge, England). vol 121. issue 4. 2001-07-19. PMID:11277875. |
other experiments have shown that expression of fas mrna and responsiveness to fas-mediated apoptosis vary in bovine granulosa and theca cells during follicle development. |
2001-07-19 |
2023-08-12 |
cattle |
| D A Porter, R M Harman, R G Cowan, S M Quir. Relationship of Fas ligand expression and atresia during bovine follicle development. Reproduction (Cambridge, England). vol 121. issue 4. 2001-07-19. PMID:11277875. |
higher concentrations of fas and fasl in cells from atretic follicles, together with the previous demonstration of increased responsiveness of granulosa cells from subordinate follicles to fasl-induced apoptosis, support a potential role for fasl-mediated apoptosis during ovarian follicle atresia. |
2001-07-19 |
2023-08-12 |
cattle |
| V Bottero, F Rossi, M Samson, M Mari, P Hofman, J F Peyro. Ikappa b-alpha, the NF-kappa B inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator. The Journal of biological chemistry. vol 276. issue 24. 2001-07-19. PMID:11287411. |
ikappab-alpha.nf-kappab appeared to be released from mitochondria upon the induction of apoptosis by engagement of the fas receptor. |
2001-07-19 |
2023-08-12 |
Not clear |
| N H Kabra, C Kang, L C Hsing, J Zhang, A Winot. T cell-specific FADD-deficient mice: FADD is required for early T cell development. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 11. 2001-07-19. PMID:11353862. |
fadd/mort1, initially identified as a fas-associated death-domain containing protein, functions as an adapter molecule in apoptosis initiated by fas, tumor necrosis factor receptor-i, dr3, and trail-receptors. |
2001-07-19 |
2023-08-12 |
mouse |
| V Poulaki, N Mitsiades, G Mastorakos, R R Caspi, G P Chrousos, E Bouza. Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone. Experimental eye research. vol 72. issue 6. 2001-07-19. PMID:11384150. |
in this study, we examined the role of apoptosis in the destruction of the retina during experimental autoimmune uveoretinitis, and the role of corticotropin-releasing hormone as a local regulator of fas and fas ligand expression in this condition. |
2001-07-19 |
2023-08-12 |
mouse |
| V Poulaki, N Mitsiades, G Mastorakos, R R Caspi, G P Chrousos, E Bouza. Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone. Experimental eye research. vol 72. issue 6. 2001-07-19. PMID:11384150. |
we evaluated apoptosis by the terminal deoxynucleotidyl transferase dutp nick end labeling method and fas and fas ligand presence by immunohistochemistry. |
2001-07-19 |
2023-08-12 |
mouse |
| V Poulaki, N Mitsiades, G Mastorakos, R R Caspi, G P Chrousos, E Bouza. Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone. Experimental eye research. vol 72. issue 6. 2001-07-19. PMID:11384150. |
the percentage of retinal cells undergoing apoptosis and the expression of fas and fas ligand were increased in inflamed retinas in immunized lewis rats and b10.a mice, compared to controls. |
2001-07-19 |
2023-08-12 |
mouse |
| V Poulaki, N Mitsiades, G Mastorakos, R R Caspi, G P Chrousos, E Bouza. Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone. Experimental eye research. vol 72. issue 6. 2001-07-19. PMID:11384150. |
retinas from immunized b10.a mice treated with anti-corticotropin-releasing hormone antibody showed significantly lower apoptosis and fas and fas ligand expression than placebo-treated animals. |
2001-07-19 |
2023-08-12 |
mouse |
| V Poulaki, N Mitsiades, G Mastorakos, R R Caspi, G P Chrousos, E Bouza. Fas/Fas ligand-associated apoptosis in experimental autoimmune uveoretinitis in rodents: role of proinflammatory corticotropin-releasing hormone. Experimental eye research. vol 72. issue 6. 2001-07-19. PMID:11384150. |
in conclusion, retinal cells in experimental autoimmune uveoretinitis undergo apoptosis associated with concurrent upregulation of fas and fas ligand. |
2001-07-19 |
2023-08-12 |
mouse |
| B W Richter, S S Mir, L J Eiben, J Lewis, S B Reffey, A Frattini, L Tian, S Frank, R J Youle, D L Nelson, L D Notarangelo, P Vezzoni, H O Fearnhead, C S Ducket. Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family. Molecular and cellular biology. vol 21. issue 13. 2001-07-19. PMID:11390657. |
in contrast to ilp-1, overexpression of ilp-2 had no protective effect on apoptosis mediated by fas (also known as cd95) or tumor necrosis factor. |
2001-07-19 |
2023-08-12 |
human |
| V Daniel, C Süsal, R Weimer, R Zimmermann, A Huth-Kühne, G Opel. Increased soluble Fas in HIV-infected hemophilia patients with CD4+ and CD8+ cell count increases and viral load and immune complex decreases. AIDS research and human retroviruses. vol 17. issue 4. 2001-07-12. PMID:11242519. |
previous studies interpreted increases of soluble fas (sfas) in the plasma during disease progression in hiv-infected patients as evidence of increased apoptosis of cd4(+) lymphocytes. |
2001-07-12 |
2023-08-12 |
Not clear |
| G Dong, E Loukinova, Z Chen, L Gangi, T I Chanturita, E T Liu, C Van Wae. Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis, and the NF-kappaB signal pathway. Cancer research. vol 61. issue 12. 2001-07-12. PMID:11406555. |
alterations in the expression of several genes detected during tumor progression were consistent with their functional activities involving growth (p21, p27, and cyclin d1), resistance and apoptosis (glutathione-s-transferase, ciap-1, pea-15, and fas ligand), inflammation and angiogenesis [chemokine growth-regulated oncogene 1 (also called kc)], and signal transduction (c-met, yes-associated protein, and syk). |
2001-07-12 |
2023-08-12 |
mouse |